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Aliases for CCSER1 Gene

Aliases for CCSER1 Gene

  • Coiled-Coil Serine Rich Protein 1 2 3 5
  • Coiled-Coil Serine-Rich Protein 1 2 3 4
  • Family With Sequence Similarity 190, Member A 2 3
  • FAM190A 3 4
  • Protein FAM190A 3
  • KIAA1680 4

External Ids for CCSER1 Gene

Previous HGNC Symbols for CCSER1 Gene

  • FAM190A

Previous GeneCards Identifiers for CCSER1 Gene

  • GC04P091049

Summaries for CCSER1 Gene

GeneCards Summary for CCSER1 Gene

CCSER1 (Coiled-Coil Serine Rich Protein 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCSER1 Gene

Genomics for CCSER1 Gene

Regulatory Elements for CCSER1 Gene

Promoters for CCSER1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCSER1 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCSER1 Gene

Chromosome:
4
Start:
90,127,394 bp from pter
End:
91,602,219 bp from pter
Size:
1,474,826 bases
Orientation:
Plus strand

Genomic View for CCSER1 Gene

Genes around CCSER1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCSER1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCSER1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCSER1 Gene

Proteins for CCSER1 Gene

  • Protein details for CCSER1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9C0I3-CCSE1_HUMAN
    Recommended name:
    Serine-rich coiled-coil domain-containing protein 1
    Protein Accession:
    Q9C0I3
    Secondary Accessions:
    • Q4W5M0
    • Q86V57

    Protein attributes for CCSER1 Gene

    Size:
    900 amino acids
    Molecular mass:
    99510 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB21771.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CCSER1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCSER1 Gene

Proteomics data for CCSER1 Gene at MOPED

Post-translational modifications for CCSER1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCSER1 Gene

Domains & Families for CCSER1 Gene

Protein Domains for CCSER1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCSER1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9C0I3

UniProtKB/Swiss-Prot:

CCSE1_HUMAN :
  • Belongs to the CCSER family.
Family:
  • Belongs to the CCSER family.
genes like me logo Genes that share domains with CCSER1: view

No data available for Gene Families for CCSER1 Gene

Function for CCSER1 Gene

genes like me logo Genes that share phenotypes with CCSER1: view

Animal Model Products

CRISPR Products

miRNA for CCSER1 Gene

miRTarBase miRNAs that target CCSER1

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCSER1 Gene

Localization for CCSER1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CCSER1 Gene

Pathways & Interactions for CCSER1 Gene

SuperPathways for CCSER1 Gene

No Data Available

Interacting Proteins for CCSER1 Gene

Selected Interacting proteins: Q9C0I3-CCSE1_HUMAN for CCSER1 Gene via I2D

Symbol External ID(s) Details
NDEL1

Gene Ontology (GO) - Biological Process for CCSER1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCSER1 Gene

Drugs & Compounds for CCSER1 Gene

No Compound Related Data Available

Transcripts for CCSER1 Gene

Unigene Clusters for CCSER1 Gene

Coiled-coil serine-rich protein 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCSER1 Gene

No ASD Table

Relevant External Links for CCSER1 Gene

GeneLoc Exon Structure for
CCSER1
ECgene alternative splicing isoforms for
CCSER1

Expression for CCSER1 Gene

mRNA expression in normal human tissues for CCSER1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCSER1 Gene

This gene is overexpressed in Testis (x4.8).

Protein differential expression in normal tissues from HIPED for CCSER1 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCSER1 Gene



SOURCE GeneReport for Unigene cluster for CCSER1 Gene Hs.654735

genes like me logo Genes that share expression patterns with CCSER1: view

Protein tissue co-expression partners for CCSER1 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for CCSER1 Gene

Orthologs for CCSER1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCSER1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCSER1 36
  • 99 (a)
OneToOne
FAM190A 35
  • 99.41 (n)
  • 99.11 (a)
cow
(Bos Taurus)
Mammalia CCSER1 36
  • 87 (a)
OneToOne
CCSER1 35
  • 89.98 (n)
  • 89.1 (a)
dog
(Canis familiaris)
Mammalia FAM190A 35
  • 91.81 (n)
  • 90.56 (a)
CCSER1 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccser1 16
Ccser1 36
  • 79 (a)
OneToOne
Ccser1 35
  • 81.45 (n)
  • 79.44 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia CCSER1 36
  • 64 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccser1 35
  • 81.34 (n)
  • 80.23 (a)
chicken
(Gallus gallus)
Aves FAM190A 35
  • 70.34 (n)
  • 67.04 (a)
CCSER1 36
  • 63 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCSER1 36
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccser1 35
  • 63.03 (n)
  • 55.1 (a)
zebrafish
(Danio rerio)
Actinopterygii CCSER1 36
  • 45 (a)
OneToOne
si:dkey-53d10.1 35
  • 56.37 (n)
  • 53.68 (a)
Species with no ortholog for CCSER1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCSER1 Gene

ENSEMBL:
Gene Tree for CCSER1 (if available)
TreeFam:
Gene Tree for CCSER1 (if available)

Paralogs for CCSER1 Gene

No data available for Paralogs for CCSER1 Gene

Variants for CCSER1 Gene

Sequence variations from dbSNP and Humsavar for CCSER1 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs12647859 - 90,309,428(+) AAAAT(A/G)GTGAA nc-transcript-variant, reference, missense
rs908189 -- 90,654,391(+) TCTTC(C/T)TTTTA intron-variant
rs446661 -- 90,516,746(+) CATTA(A/G)AATTT intron-variant
rs919578 -- 90,234,941(+) TTGCT(C/G)TGCTC intron-variant, upstream-variant-2KB
rs189780 -- 90,551,483(-) CAAAA(A/G)ATGGG intron-variant

Variation tolerance for CCSER1 Gene

Residual Variation Intolerance Score: 62.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.30; 81.38% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCSER1 Gene

HapMap Linkage Disequilibrium report
CCSER1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCSER1 Gene

Disorders for CCSER1 Gene

Relevant External Links for CCSER1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCSER1

No disorders were found for CCSER1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCSER1 Gene

Publications for CCSER1 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11214970) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 67
  2. Genetic loci associated with circulating levels of very long-chain saturated fatty acids. (PMID: 25378659) Lemaitre R.N. … Friedlander Y. (J. Lipid Res. 2015) 3
  3. No evidence of gene-calcium interactions from genome-wide analysis of colorectal cancer risk. (PMID: 25192705) Du M. … Potter J.D. (Cancer Epidemiol. Biomarkers Prev. 2014) 3
  4. Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations. (PMID: 24529757) Xie T. … Xu R. (Neurobiol. Aging 2014) 3
  5. GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association. (PMID: 23725790) RenterA-a M.E. … Medland S.E. (Twin Res Hum Genet 2013) 3

Products for CCSER1 Gene

Sources for CCSER1 Gene

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