Aliases for CCSAP Gene
External Ids for CCSAP Gene
Previous HGNC Symbols for CCSAP Gene
Previous GeneCards Identifiers for CCSAP Gene
GeneCards Summary for CCSAP Gene
CCSAP (Centriole, Cilia And Spindle Associated Protein) is a Protein Coding gene. Diseases associated with CCSAP include Colonic Benign Neoplasm.
UniProtKB/Swiss-Prot for CCSAP Gene
Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle (PubMed:26562023). May play a role in embryonic development. May be required for proper cilia beating (By similarity).