CCS Gene
protein-coding GIFtS: 62
GCID: GC11P066360
|
|
copper chaperone for superoxide dismutase
| |
Aliases
for CCS gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Copper Chaperone For Superoxide Dismutase1 2 | | Superoxide Dismutase Copper Chaperone2 3 |
Export aliases for CCS gene to outside databasesPrevious GC identifers: GC11P068894 GC11P068043 GC11P066610 GC11P066136 GC11P066117 GC11P062688 |
Summaries
for CCS gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CCS:
Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activatecopper/zinc superoxide dismutase through direct insertion of the Cu cofactor. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CCS_HUMAN, O14618Function: Delivers copper to copper zinc superoxide dismutase (SOD1)
Gene Wiki entry for CCS
|
Genomic Views
for CCS gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCS gene promoter:
c-Fos C/EBPbeta GATA-3 GATA-2 GATA-1 CREB PPAR-gamma1 deltaCREB c-Myb PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCS
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCS |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13 Ensembl cytogenetic band: 11q13.2 HGNC cytogenetic band: 11q13.2CCS Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P066360: view genomic region
(about GC identifiers)
Start:
|
66,360,292 bp from pter |
End:
|
66,373,490 bp from pter |
Size:
|
13,199 bases |
Orientation:
|
plus strand |
|
Proteins
for CCS gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CCS_HUMAN, O14618 (See
protein sequence)Recommended Name: Copper chaperone for superoxide dismutase Size: 274 amino acids; 29041 Da
Cofactor: Binds 2 copper ions per subunit
Cofactor: Binds 1 zinc ion per subunit
Subunit: Homodimer, and heterodimer with SOD1. Interacts with COMMD1. Interacts with XIAP/BIRC4
Subcellular location: Cytoplasm
2 PDB 3D structures from  and Proteopedia  for CCS:1DO5 (3D)
2CRL (3D)
Secondary accessions: Q2M366Explore the universe of human proteins at neXtProt for CCS: NX_O14618
Post-translational modifications:
Ubiquitinion by XIAP/BIRC4 leads to enhancement of its chaperone activity toward its physiologic target, SOD1, ratherthan proteasomal degradation. XIAP/BIRC4 preferentially ubiquitinates at Lys-2411
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O14618
CCS Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_005116.1
ENSEMBL proteins: ENSP00000436318 ENSP00000433609 ENSP00000307870 ENSP00000436379
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
CCS for ontologies About GeneDecksing
CCS Antibody Products:
Assay Products for CCS: |
Protein
Domains /
Families
for CCS gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CCS for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O14618ProtoNet protein and cluster: O14618 2 Blocks protein families: IPB001424 Copper/Zinc superoxide dismutase IPB006121 Heavy metal transport/detoxification protein
UniProtKB/Swiss-Prot: CCS_HUMAN, O14618Similarity: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase familySimilarity: Contains 1 HMA domain |
Function
for CCS gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CCS_HUMAN, O14618Function: Delivers copper to copper zinc superoxide dismutase (SOD1) Genatlas biochemistry entry for CCS:copper chaperone for superoxide dismutase,S cerevisiae LYS7 ortholog
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCS (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCS
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): CCS (NM_005333) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCS | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCS |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCS |
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8): About this table
CCS for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for CCS:
Animal Models:
Mouse knock-out Ccstm1Pcw for CCS
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Ccs):
CCS for phenotypes About GeneDecksing
|
Pathways & Interactions
for CCS gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Pathogenesis of ALS | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for CCS):
CCS for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CCS
STRING Interaction
Network Preview (showing 5 interactants - click image to see 18)
5/20 Interacting proteins for CCS (O146183 ENSP000003078704) via UniProtKB, MINT, STRING, and/or I2D (see all 20)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
CCS for ontologies About GeneDecksing
|
Drugs & Compounds
for CCS gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CCS for compounds About GeneDecksing
 Browse Tocris compounds for CCS
2 HMDB Compounds for CCS About this table
6 Novoseek chemical compound relationships for CCS gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| zinc superoxide |
77.4 |
3 |
9726962 (1), 9886096 (1), 16531609 (1) |
| copper |
77 |
103 |
12832419 (7), 16531609 (7), 12815046 (4), 11473116 (3) (see all 24) |
| superoxide |
65.8 |
20 |
20154138 (2), 15064408 (2), 15993338 (1), 17504097 (1) (see all 13) |
| zinc |
48.7 |
2 |
12832419 (1), 19227972 (1) |
| cysteine |
36.6 |
4 |
12832419 (1), 16531609 (1), 18703498 (1) |
| oxygen |
3.35 |
7 |
15064408 (3), 18703498 (2) |
Search CenterWatch for drugs/clinical trials and news about CCS
|
Transcripts
for CCS gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCS gene: NM_005125.1 Unigene Cluster for CCS: Copper chaperone for superoxide dismutase Hs.502917 [show with all ESTs]Unigene Representative Sequence: BM9231929 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000533244(uc001oir.3) ENST00000530384 ENST00000526066 ENST00000530961
ENST00000526058 ENST00000531990 ENST00000310190 ENST00000534763 ENST00000525435
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCS (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCS
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): CCS (NM_005333) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCS | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCS |
Additional cDNA sequence: AF002210.1 AY113179.1 BC105016.1 BC112055.1 CR541928.1 13 DOTS entries: DT.451899 DT.95218453 DT.95297325 DT.403494 DT.95297322 DT.95297334 DT.100789265 DT.120718131 DT.120718145 DT.120718151 DT.97845684 DT.100789268 DT.97778415 24/217 AceView cDNA sequences (see all 217): AI620531 BQ651373 BX089413 AF002210 BM725666 BQ082347 AA602749 NM_005125 BQ939809 CF131037 BI834271 CR618281 CD251514 BQ708701 BQ082527 CA454771 BQ447121 CB105001 BE549602 CR592698 BP428609 BQ082516 BX494931 AI300401
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CCS (see all 8) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · | 8b |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | - | | - | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CCS
|
Expression
for CCS gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCS expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGGCCCCCA
About this image
See CCS Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCS
SOURCE GeneReport for Unigene cluster: Hs.502917
UniProtKB/Swiss-Prot: CCS_HUMAN, O14618Tissue specificity: Ubiquitous
SABiosciences Expression via Pathway-Focused PCR Arrays including CCS:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCS
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CCS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCS | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCS |
Orthologs
for CCS gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for CCS gene from 7/24 species (see all 24) About this table
ENSEMBL Gene Tree for CCS (if available)
TreeFam Gene Tree for CCS (if available) |
Paralogs
for CCS gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CCS gene
- SOD12 SOD32
1 SIMAP similar gene for CCS using alignment to 5 protein entries: CCS_HUMAN (see all proteins):SOD1
CCS for paralogs About GeneDecksing
|
Genomic Variants
for CCS gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCS (66360292 - 66373490 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CCS: --
Human Gene Mutation Database (HGMD): CCS
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCS |
|
Disorders
/ Diseases
for CCS gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CCS for disorders About GeneDecksing
OMIM gene information: 603864
OMIM disorders: --
9  diseases for CCS: About MalaCardsamyotrophic lateral sclerosis amyotrophic lateral sclerosis (als) choledochal cyst lateral sclerosis
anus neoplasm hemopericardium alzheimer's disease cholangiocarcinoma
neuronitis
3 diseases from the University of Copenhagen DISEASES database for CCS:Cholangiocarcinoma Apical myocardial infarction Hemopericardium 2 Novoseek disease relationships for CCS gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| amyotrophic lateral sclerosis |
79.6 |
5 |
10793232 (2), 17504097 (1), 11585247 (1) |
| alzheimers disease |
1.1 |
1 |
17504097 (1) |
Human Genome Epidemiology (HuGE) Navigator: CCS (7 documents)
Export disorders for CCS gene to outside databases
|
Publications
for CCS gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCS gene, integrated from 9 sources (see all 51):
(articles sorted by number of sources associating them with CCS) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The copper chaperone for superoxide dismutase. (PubMed id 9295278)1, 2, 3 Culotta V.C....Gitlin J.D. (1997)
- The copper chaperone CCS directly interacts with copper/zinc superoxide dismutase. (PubMed id 9726962)1, 2, 9 Casareno R.L.B.... Gitlin J.D. (1998)
- Regulation of the copper chaperone CCS by XIAP-mediat ed ubiquitination. (PubMed id 20154138)1, 2, 9 Brady G.F....Duckett C.S. (2010)
- Cysteine-to-serine mutants of the human copper chaperone for superoxide dismutase reveal a copper cluster at a domain III dimer interface. (PubMed id 15736924)1, 2, 9 Stasser J.P.... Blackburn N.J. (2005)
- Molecular and biochemical characterization of a unique mutation in CCS, the human copper chaperone to superoxide dismutase. (PubMed id 22508683)1, 2 Huppke P.... Gartner J. (2012)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Crystal structure of the second domain of the human copper chaperone for superoxide dismutase. (PubMed id 10677207)1, 2 Lamb A.L....Rosenzweig A.C. (2000)
- The copper chaperone CCS is abundant in neurons and astrocytes in human and rodent brain. (PubMed id 9886096)1, 9 Rothstein J.D....Wong P.C. (1999)
- Mechanisms of the copper-dependent turnover of the copper chaperone for superoxide dismutase. (PubMed id 16531609)1, 9 Caruano-Yzermans A.L....Gitlin J.D. (2006)
- Copper modulates the degradation of copper chaperone for Cu,Zn superoxide dismutase by the 26 S proteosome. (PubMed id 12832419)1, 9 Bertinato J. and L'Abbe M.R. (2003)
|
External Searches for CCS gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCS gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCS gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCS gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCS | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CCS gene:
Search GeneIP for patents involving CCS
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCS gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CCS | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCS | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCS | | | OriGene Protein Over-expression Lysate for CCS | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCS | | OriGene 3'-UTR Clone for CCS | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCS | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCS | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCS | | OriGene Custom Protein Services for CCS | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCS | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCS | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCS | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCS |
| |
 |  |  |  | |
| | | | Search Tocris compounds for CCS |
| |  |  |  |  | | | | | | Recombinant Protein for CCS |
|
 |
 |
 |
 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCS |
|  |  |  | | | | ThermoFisher Antibodies for CCS |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCS |
|
|
|
|
