Aliases for CCS Gene
Aliases for CCS Gene
External Ids for CCS Gene
- HGNC: 1613
- Entrez Gene: 9973
- Ensembl: ENSG00000173992
- OMIM: 603864
- UniProtKB: O14618
Previous GeneCards Identifiers for CCS Gene
- GC11P068894
- GC11P068043
- GC11P066610
- GC11P066136
- GC11P066117
- GC11P066360
- GC11P062688
Summaries for CCS Gene
-
Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008]
GeneCards Summary for CCS Gene
CCS (Copper Chaperone For Superoxide Dismutase) is a Protein Coding gene. Diseases associated with CCS include Entropion and Amyotrophic Lateral Sclerosis 1. Among its related pathways are Detoxification of Reactive Oxygen Species and Amyotrophic lateral sclerosis (ALS). Gene Ontology (GO) annotations related to this gene include copper ion binding and copper ion transmembrane transporter activity. An important paralog of this gene is SOD1.
UniProtKB/Swiss-Prot for CCS Gene
-
Delivers copper to copper zinc superoxide dismutase (SOD1).
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCS Gene
Genomics for CCS Gene
GeneHancer (GH) Regulatory Elements for CCS Gene
Promoters and enhancers for CCS Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CCS on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the CCS gene promoter:
Regulatory Element Products
Genomic Locations for CCS Gene
Genomic Locations for CCS Gene
- chr11:66,592,821-66,606,019
- (GRCh38/hg38)
- Size:
- 13,199 bases
- Orientation:
- Plus strand
- chr11:66,360,292-66,373,490
- (GRCh37/hg19)
Genomic View for CCS Gene
Genes around CCS on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q13.2 by Ensembl
- 11q13.2 by Entrez Gene
- 11q13.2 by HGNC
CCS Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CCS Gene
Proteins for CCS Gene
-
Protein details for CCS Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O14618-CCS_HUMAN
- Recommended name:
- Copper chaperone for superoxide dismutase
- Protein Accession:
- O14618
- Q2M366
- Q8NEV0
Protein attributes for CCS Gene
- Size:
- 274 amino acids
- Molecular mass:
- 29041 Da
- Cofactor:
- Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
- Cofactor:
- Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
- Quaternary structure:
-
- Homodimer, and heterodimer with SOD1. Interacts with COMMD1. Interacts with XIAP/BIRC4.
Protein Expression for CCS Gene
Post-translational modifications for CCS Gene
- Ubiquitinion by XIAP/BIRC4 leads to enhancement of its chaperone activity toward its physiologic target, SOD1, rather than proteasomal degradation. XIAP/BIRC4 preferentially ubiquitinates at Lys-241.
- Ubiquitination at Lys76, posLast=189189, Lys216, and Lys241
Other Protein References for CCS Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CCS
- Novus Biologicals Antibodies for CCS
-
Abcam antibodies for CCS
-
Cloud-Clone Corp. Antibodies for CCS
- Invitrogen Antibodies for CCS
- Search GeneTex for Antibodies for CCS
Protein Products
-
OriGene Purified Proteins for CCS
- Search Origene for MassSpec and Protein Over-expression Lysates for CCS
- Origene Custom Protein Services for CCS
- ProSpec Recombinant Proteins for CCS
-
Cloud-Clone Corp. Proteins for CCS
- Search GeneTex for Proteins for CCS
-
Abcam proteins for CCS
Assay Products
-
Cloud-Clone Corp. Assay Kits for CCS
No data available for DME Specific Peptides for CCS Gene
Domains & Families for CCS Gene
Gene Families for CCS Gene
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for CCS Gene
Suggested Antigen Peptide Sequences for CCS Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O14618UniProtKB/Swiss-Prot:
CCS_HUMAN :- In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.
- Family:
-
- In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.
Function for CCS Gene
Molecular function for CCS Gene
- GENATLAS Biochemistry:
- copper chaperone for superoxide dismutase,S cerevisiae LYS7 ortholog
- UniProtKB/Swiss-Prot Function:
- Delivers copper to copper zinc superoxide dismutase (SOD1).
Phenotypes From GWAS Catalog for CCS Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004784 | NOT superoxide dismutase activity | IBA | -- |
| GO:0005507 | copper ion binding | IDA | 9726962 |
| GO:0005515 | protein binding | IPI | 9726962 |
| GO:0008270 | zinc ion binding | IBA | -- |
| GO:0015035 | protein disulfide oxidoreductase activity | TAS | -- |
Phenotypes for CCS Gene
- MGI mutant phenotypes for CCS:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CCS:
-
- Increased vaccinia virus (VACV) infection
- Decreased hepcidin::fluc mRNA expression
- Dynamic nuclei (hole, folded or small irregular)
- Resistant to vaccinia virus (VACV-A4L) infection
- Negative genetic interaction between PTEN-/- and PTEN+/+
- Synthetic lethal with MLN4924 (a NAE inhibitor)
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Increased cilium length after serum starvation
Animal Models for CCS Gene
- MGI Knock Outs for CCS:
-
- Ccs tm1Pcw
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCS
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CCS gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCS gene
- Search ViGene Biosciences for CCS
CRISPR Products
-
OriGene CRISPR knockouts for CCS
- Applied Biological Materials CRISPR for CCS
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCS
- GenScript: Design CRISPR guide RNA sequences for CCS
miRNA for CCS Gene
- miRTarBase miRNAs that target CCS
-
- ath-mir398a-3p (MIRT005464)
- ath-mir398b-3p (MIRT005465)
- ath-mir398c-3p (MIRT005466)
- hsa-mir-484 (MIRT042263)
- hsa-mir-5698 (MIRT617435)
- hsa-mir-744-3p (MIRT617436)
- hsa-mir-4423-5p (MIRT617437)
- hsa-mir-6501-5p (MIRT617438)
- hsa-mir-891a-3p (MIRT617439)
- hsa-mir-143-5p (MIRT617440)
- hsa-mir-4430 (MIRT617441)
- hsa-mir-3652 (MIRT617442)
- hsa-mir-593-5p (MIRT617443)
- hsa-mir-122-5p (MIRT617444)
- hsa-mir-504-3p (MIRT617445)
- hsa-mir-3135b (MIRT617446)
- hsa-mir-6499-3p (MIRT617447)
- hsa-mir-767-5p (MIRT617448)
- hsa-mir-367-5p (MIRT617449)
- hsa-mir-1267 (MIRT617450)
- hsa-mir-4638-5p (MIRT617451)
- hsa-mir-1307-3p (MIRT617452)
- hsa-mir-6741-3p (MIRT617453)
- hsa-mir-5693 (MIRT617454)
- hsa-mir-1303 (MIRT617455)
- hsa-mir-5096 (MIRT617456)
- hsa-mir-6802-3p (MIRT617457)
- hsa-mir-411-5p (MIRT617458)
- hsa-mir-4662a-5p (MIRT617459)
- hsa-mir-6832-5p (MIRT617460)
- hsa-mir-193b-5p (MIRT617461)
- hsa-mir-3620-3p (MIRT617462)
- hsa-mir-6865-3p (MIRT617463)
- hsa-mir-575 (MIRT617464)
- hsa-mir-4676-5p (MIRT617465)
- hsa-mir-6858-3p (MIRT617466)
- hsa-mir-483-5p (MIRT617467)
- hsa-mir-10b-5p (MIRT617468)
- hsa-mir-10a-5p (MIRT617469)
- hsa-mir-129-5p (MIRT625164)
- hsa-mir-372-5p (MIRT625165)
- hsa-mir-371a-5p (MIRT625166)
- hsa-mir-616-5p (MIRT625167)
- hsa-mir-373-5p (MIRT625168)
- hsa-mir-371b-5p (MIRT625169)
- hsa-mir-3613-3p (MIRT625170)
- hsa-mir-4282 (MIRT625171)
- hsa-mir-3149 (MIRT642899)
- hsa-mir-7850-5p (MIRT661456)
- hsa-mir-620 (MIRT661457)
- hsa-mir-1270 (MIRT661458)
- hsa-mir-4531 (MIRT661459)
- hsa-mir-6812-3p (MIRT671243)
- hsa-mir-4284 (MIRT672737)
- hsa-mir-2276-3p (MIRT672738)
- hsa-mir-365b-5p (MIRT678034)
- hsa-mir-365a-5p (MIRT678035)
- hsa-mir-8052 (MIRT678036)
- hsa-mir-3199 (MIRT678037)
- hsa-mir-150-5p (MIRT678038)
- hsa-mir-6814-5p (MIRT678039)
- hsa-mir-122-3p (MIRT678040)
- hsa-mir-582-3p (MIRT678041)
- hsa-mir-5089-5p (MIRT683461)
- hsa-mir-6807-5p (MIRT683462)
- hsa-mir-7151-3p (MIRT683463)
- hsa-mir-5095 (MIRT683464)
- hsa-mir-5589-5p (MIRT683465)
- hsa-mir-4731-5p (MIRT683466)
- hsa-mir-6506-5p (MIRT683467)
- hsa-mir-619-5p (MIRT683468)
- hsa-mir-1292-3p (MIRT683469)
- hsa-mir-6504-3p (MIRT683470)
- hsa-mir-512-3p (MIRT683471)
- hsa-mir-4438 (MIRT683472)
- hsa-mir-597-5p (MIRT706597)
- hsa-mir-6778-3p (MIRT706598)
- hsa-mir-6747-3p (MIRT706599)
- hsa-mir-4740-3p (MIRT706600)
- hsa-mir-6715b-5p (MIRT706601)
- hsa-mir-4269 (MIRT706602)
- hsa-mir-3622a-5p (MIRT706603)
miRNA Products
- Search ViGene Biosciences for CCS
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CCS
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-
ViGene Biosciences ready-to-package AAV shRNAs for CCS gene
Clone Products
- Sino Biological Human cDNA Clone for CCS
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CCS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCS
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for 116 available Superoxide dismutase copper chaperone gene related products
- Overview of 116 available Superoxide dismutase copper chaperone gene related products
- orf clones - Search results for 116 available Superoxide dismutase copper chaperone gene related products
- Overview of 116 available Superoxide dismutase copper chaperone gene related products
- Applied Biological Materials Clones for CCS
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for CCS
-
ViGene Biosciences adenoviral particle packaged cDNA for CCS gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CCS gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCS gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CCS Gene
Localization for CCS Gene
Subcellular locations from UniProtKB/Swiss-Prot for CCS Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| extracellular | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005615 | NOT extracellular space | IBA | -- |
| GO:0005634 | nucleus | IDA | 9726962 |
| GO:0005737 | cytoplasm | IEA,IDA | 9726962 |
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CCS Gene
Pathways & Interactions for CCS Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Amyotrophic lateral sclerosis (ALS) | ||
| 2 | Cellular Senescence (REACTOME) | ||
| 3 | Detoxification of Reactive Oxygen Species | ||
| 4 | Copper homeostasis | ||
Pathways by source for CCS Gene
2 BioSystems pathways for CCS Gene
2 Reactome pathways for CCS Gene
1 KEGG pathway for CCS Gene
Interacting Proteins for CCS Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006801 | superoxide metabolic process | IEA | -- |
| GO:0015680 | intracellular copper ion transport | TAS | 9726962 |
| GO:0019430 | removal of superoxide radicals | IEA | -- |
| GO:0030001 | metal ion transport | IEA | -- |
| GO:0034599 | cellular response to oxidative stress | TAS | -- |
No data available for SIGNOR curated interactions for CCS Gene
Transcripts for CCS Gene
mRNA/cDNA for CCS Gene
- (1) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (217) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CCS Gene
CRISPR Products
-
OriGene CRISPR knockouts for CCS
- Applied Biological Materials CRISPR for CCS
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCS
- GenScript: Design CRISPR guide RNA sequences for CCS
miRNA Products
- Search ViGene Biosciences for CCS
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CCS
- Browse OriGene Inhibitory RNA Products For CCS
-
ViGene Biosciences ready-to-package AAV shRNAs for CCS gene
Clone Products
- Sino Biological Human cDNA Clone for CCS
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CCS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCS
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for 116 available Superoxide dismutase copper chaperone gene related products
- Overview of 116 available Superoxide dismutase copper chaperone gene related products
- orf clones - Search results for 116 available Superoxide dismutase copper chaperone gene related products
- Overview of 116 available Superoxide dismutase copper chaperone gene related products
- Applied Biological Materials Clones for CCS
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · | 8b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||
| SP7: | - | ||||||||||||||||||||||||||||||||
| SP8: | - |
Expression for CCS Gene
This gene is overexpressed in Peripheral blood mononuclear cells (6.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CCS Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CCS Gene:
CCSSOURCE GeneReport for Unigene cluster for CCS Gene:
Hs.502917mRNA Expression by UniProt/SwissProt for CCS Gene:
O14618-CCS_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for CCS Gene
- Nervous system(4.6)
- Liver(4.4)
Primer Products
-
OriGene qPCR primer pairs for CCS
-
OriGene qPCR primer pairs and template standards for CCS
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCS Gene
Orthologs for CCS Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CCS 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | CCS 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | CCS 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Ccs 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ccs 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CCS 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | CCS 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ccs 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ccs 33 34 |
|
||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.5828 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CCS 35 33 34 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP007026 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | sod-1 34 |
|
OneToMany | |
| sod-5 34 |
|
OneToMany | |||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0F26917g 33 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SOD1 34 |
|
OneToMany | |
| CCS1 33 36 |
|
||||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | CCS 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os04g0573200 33 |
|
||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU07851 33 |
|
- Species where no ortholog for CCS was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for CCS Gene
(1) SIMAP similar genes for CCS Gene using alignment to 5 proteins:
Variants for CCS Gene
| SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs142340643 | uncertain-significance, Neurodegeneration | 66,600,547(+) | C/T | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| rs1000310726 | -- | 66,596,825(+) | G/A | intron_variant | |
| rs1000727023 | -- | 66,594,179(+) | A/G | intron_variant | |
| rs1001785724 | -- | 66,601,782(+) | C/T | intron_variant | |
| rs1001857744 | -- | 66,603,630(+) | A/G | intron_variant |
Residual Variation Intolerance Score:
44.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.09;
38.26% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CCS Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCS Gene
Disorders for CCS Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| entropion |
|
|
| amyotrophic lateral sclerosis 1 |
|
|
| lateral sclerosis |
|
|
Search CCS in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CCS
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for CCS Gene
Publications for CCS Gene
- Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination. (PMID: 20154138) Brady GF … Duckett CS (Molecular and cellular biology 2010) 3 4 22 58
- Cysteine-to-serine mutants of the human copper chaperone for superoxide dismutase reveal a copper cluster at a domain III dimer interface. (PMID: 15736924) Stasser JP … Blackburn NJ (Biochemistry 2005) 3 4 22 58
- The copper chaperone CCS directly interacts with copper/zinc superoxide dismutase. (PMID: 9726962) Casareno RL … Gitlin JD (The Journal of biological chemistry 1998) 3 4 22 58
- The copper chaperone for superoxide dismutase. (PMID: 9295278) Culotta VC … Gitlin JD (The Journal of biological chemistry 1997) 2 3 4 58
- Molecular and biochemical characterization of a unique mutation in CCS, the human copper chaperone to superoxide dismutase. (PMID: 22508683) Huppke P … Gärtner J (Human mutation 2012) 3 4 58
Products for CCS Gene
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- Custom Antibody ServicesOriGene Antibodies for CCS
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- Sino Biological Human cDNA Clone for CCS
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for CCS
- Novus Biologicals proteins and lysates for CCS
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for CCS
- Abcam proteins for CCS
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ProSpec Recombinant Proteins for CCS
- Cloud-Clone Corp. Antibodies for CCS
- Cloud-Clone Corp. Proteins for CCS
- Cloud-Clone Corp. Assay Kits for CCS
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for CCS
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCS
- VectorBuilder custom plasmid, inducible vectors for CCS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCS
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for available Superoxide dismutase copper chaperone related products ranked by validation data
- antibodies-online: Search results for 16 available Superoxide dismutase copper chaperone Elisa Kits ranked by validation data
- Compare Top Superoxide dismutase copper chaperone Elisa Kits
- antibodies-online: Search results for 13 available Superoxide dismutase copper chaperone Proteins ranked by validation data
- Compare Top Superoxide dismutase copper chaperone Proteins
- Search GeneTex for Antibodies for CCS
- Search GeneTex for Proteins for CCS
- ViGene Biosciences adenoviral particle packaged cDNA for CCS gene
- ViGene Biosciences lentiviral particle packaged cDNA for CCS gene
- ViGene Biosciences ready-to-package AAV shRNAs for CCS gene
- Search ViGene Biosciences for CCS
- Search Santa Cruz Biotechnology (SCBT) for CCS siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CCS
- Horizon Cell Lines for CCS
- genomics-online: cdna clones - Search results for 116 available Superoxide dismutase copper chaperone gene related products
- Overview of 116 available Superoxide dismutase copper chaperone gene related products
- orf clones - Search results for 116 available Superoxide dismutase copper chaperone gene related products
- Overview of 116 available Superoxide dismutase copper chaperone gene related products
- genomics-online: gRNA clones - Search results for 116 available Superoxide dismutase copper chaperone gene related products
- Overview of 116 available Superoxide dismutase copper chaperone gene related products
- genomics-online: primer clones - Search results for 116 available Superoxide dismutase copper chaperone gene related products
- Overview of 116 available Superoxide dismutase copper chaperone gene related products
- genomics-online: shRNA clones - Search results for 116 available Superoxide dismutase copper chaperone gene related products
- Overview of 116 available Superoxide dismutase copper chaperone gene related products
Sources for CCS Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew