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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CCRL2 Gene

protein-coding   GIFtS: 54
GCID: GC03P046448

chemokine (C-C motif) receptor-like 2

 Explore 6 diseases affiliated with
CCRL2 via our new
 Human Malady Compendium 
Biological research products
for CCRL2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Chemokine (C-C Motif) Receptor-Like 21 2     Chemokine Receptor X2 3
CKRX1 2 3     Putative MCP-1 Chemokine Receptor2 3
HCR1 2 3     CRAM2 3
CRAM-A1 2     C-C Chemokine Receptor-Like 22
CRAM-B1 2     CCR113
Chemokine Receptor CCR112 3     CCR63

External Ids:    HGNC: 16121   Entrez Gene: 90342   Ensembl: ENSG000001217977   OMIM: 6083795   UniProtKB: O004213   

Export aliases for CCRL2 gene to outside databases

Previous GC identifers: GC03P045689 GC03P046267 GC03P046409 GC03P9F0095


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CCRL2:
This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most
closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment
of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and
primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage
differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor
gene cluster is located. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CCRL2_HUMAN, O00421
Function: Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in
modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand
to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses

Gene Wiki entry for CCRL2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CCRL2 gene promoter:
         USF1   STAT1   USF-1   STAT5A   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCRL2 promoter sequence
   Search SABiosciences Chromatin IP Primers for CCRL2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCRL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21

CCRL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCRL2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P046448:  view genomic region     (about GC identifiers)

Start:
46,448,654 bp from pter      End:
46,451,014 bp from pter
Size:
2,361 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CCRL2_HUMAN, O00421 (See protein sequence)
Recommended Name: C-C chemokine receptor-like 2  
Size: 344 amino acids; 39513 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Miscellaneous: It was initially reported that CCRL2 responds functionally to CCL2, CCL5, CCL7, and CCL8 via
intracellular calcium mobilization and transwell chemotaxis although no evidence for a direct ligand-receptor
interaction was provided in this report. These results are now controversial, and other studies failed to confirm
CCRL2 recognition and transwell chemotaxis of these chemokines or a series of other CC- and CXC-chemokines using
CCRL2-transfected cells (PubMed:15188357)
Secondary accessions: B4DKQ8 O75307 Q4VBB0 Q6IPX0 Q7KYQ9 Q96KP5 Q9UPG0
Alternative splicing: 2 isoforms:  O00421-1   O00421-2   

Explore the universe of human proteins at neXtProt for CCRL2: NX_O00421

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O00421

  • CCRL2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001124382.1  NP_003956.2  

    ENSEMBL proteins: 
     ENSP00000381994   ENSP00000349967   ENSP00000383677   ENSP00000414957   ENSP00000383678  

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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CCRL2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral to plasma membrane IDA--
    GO:0016021integral to membrane ----


    CCRL2 for ontologies           About GeneDecksing



    CCRL2 Antibody Products: 
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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CCRL2 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR000355 Chemokine_rcpt
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry O00421

    ProtoNet protein and cluster: O00421

    1 Blocks protein family: IPB000355 Chemokine receptor signature

    UniProtKB/Swiss-Prot: CCRL2_HUMAN, O00421
    Domain: Lacks the conserved DRYLAIV motif in the second intracellular loop that is required for signaling of functional
    chemokine receptors
    Similarity: Belongs to the G-protein coupled receptor 1 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CCRL2_HUMAN, O00421
    Function: Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in
    modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand
    to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses
    Induction: Up-regulated by CCL5 on the pre-B-cell lines NALM-6 and G2

         Genatlas biochemistry entry for CCRL2:
    chemokine CC,beta receptor like 3,G protein coupled receptor superfamily

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    1 QIAGEN miScript miRNA Assays for microRNA that regulate CCRL2:
    hsa-miR-3919
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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCRL2

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004950chemokine receptor activity IEA--
    GO:0042379chemokine receptor binding IPI14530373
    GO:0048020CCR chemokine receptor binding IPI--


    CCRL2 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for CCRL2: Ccrl2tm1Ssoz Ccrl2tm1Lex Ccrl2tm1Dgen
         3 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Ccrl2):
     cellular  immune system  normal 

    CCRL2 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Akt Signaling
    Akt Signaling1.00
    Tec Kinases Signaling0.55
    p38 Signaling0.60
    2Chemokine Signaling
    Chemokine Signaling1.00
    3PAK Pathway
    Antioxidant Action of Vitamin-C0.56
    4Rho Family GTPases
    Molecular Mechanisms of Cancer0.51
    5PEDF Induced Signaling
    STAT3 Pathway0.47

    5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CCRL2 (see all 7)
        Chemokine Signaling
    STAT3 Pathway
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C
    p38 Signaling

    1 BioSystems Pathway for CCRL2 
        GPCRs, Class A Rhodopsin-like


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCRL2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for CCRL2 (O004213 ENSP000003499674) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCL19Q997313I2D: score=1 
    FAM107BENSP000001817964STRING: ENSP00000181796
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006935chemotaxis TAS9473515
    GO:0006954inflammatory response ISS--
    GO:0007186G-protein coupled receptor signaling pathway TAS9473515
    GO:0070098chemokine-mediated signaling pathway TAS9473515


    CCRL2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CCRL2
    Search CenterWatch for drugs/clinical trials and news about CCRL2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CCRL2 gene (2 alternative transcripts): 
    NM_001130910.1  NM_003965.4  

    Unigene Cluster for CCRL2:

    Chemokine (C-C motif) receptor-like 2
    Hs.535713  [show with all ESTs]
    Unigene Representative Sequence: AF015525
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000399036(uc003cpp.4) ENST00000495870 ENST00000357392(uc010hjg.3 uc010hjf.3)
    ENST00000400880 ENST00000433848 ENST00000400882(uc021wxc.1)

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    1 QIAGEN miScript miRNA Assays for microRNA that regulate CCRL2:
    hsa-miR-3919
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    Inhib. RNA
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    Additional cDNA sequence: 

    AF014958.1 AF015524.1 AF015525.1 AJ344142.1 AK296673.1 AK313312.1 AY337001.1 BC025717.1 
    BC071682.1 BC096075.1 BC096076.3 BC099623.3 

    2 DOTS entries:

    DT.105784  DT.100746890 

    24/25 AceView cDNA sequences (see all 25):

    CD370587 BC025717 AI954582 AF014958 AY337001 NM_003965 BE465578 BI819787 
    AW300833 CD520843 BQ892457 AF015524 BE871331 AJ344142 BV174724 BI834559 
    AI343408 AF015525 CF147784 BG386374 BX480211 AI288845 AW293465 AW236610 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for CCRL2    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b · 3c
    SP1:        -     -     -                     
    SP2:                    -                     
    SP3:                                          


    ECgene alternative splicing isoforms for CCRL2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CCRL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAATAAATGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See CCRL2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CCRL2

    SOURCE GeneReport for Unigene cluster: Hs.535713

    UniProtKB/Swiss-Prot: CCRL2_HUMAN, O00421
    Tissue specificity: Expressed abundantly in immunal tissues such as spleen, fetal liver, lymph node and bone marrow.
    Strong expression also in lung and heart. Expressed in almost all hematopoietic cells including monocytes,
    macrophages, PMNs, T-cells (both CD4+ and CD8+), monocyte-derived iDCs, NK cells, and CD34+ progenitor cells. B-cells
    expressed isoform 1 but not isoform 2. Up-regulated on synovial neutrophils of rheumatoid arthritis patients

        SABiosciences Expression via Pathway-Focused PCR Arrays including CCRL2: 
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              Chemokines & Receptors in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCRL2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CCRL2 gene from 3/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves F1NPK9_CHICK6
    F1NPK8_CHICK6
    chemokine (C-C motif) receptor 2
    34(a)
    33(a)
    many ↔ many
    many ↔ many
    2(42682320-42683396)
    2(42699264-42700328)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    --
    37(a)
    34(a)
    many ↔ many
    many ↔ many
    GL343324.1(448159-449136)
    GL343324.1(443935-445008)
    zebrafish
    (Danio rerio)
    Actinopterygii CU467889.16
    ccr8.16
    (see all 3)
    chemokine (C-C motif) receptor 8.1
    (see all 3)
    25(a)
    24(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    16(11002252-11005272)
    16(10749803-10752840)


    ENSEMBL Gene Tree for CCRL2 (if available)
    TreeFam Gene Tree for CCRL2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CCRL2 gene
    CCR62  CCR52  CXCR62  CXCR32  XCR12  CCR92  CCBP22  CCR72  
    CX3CR12  CCR82  CXCR22  CCRL12  CCR42  CCR12  CXCR12  CCR22  
    CXCR52  CCR102  CCR32  CXCR42  
    14 SIMAP similar genes for CCRL2 using alignment to 3 protein entries:     CCRL2_HUMAN (see all proteins):
    CCR3    GHSR    CCR2    CCR5    CCR-5    CCBP2
    CCR1    CX3CR1    CCR8    CCR4    CCR7    CXCR6
    XCR1    AGTR1

    CCRL2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/103 NCBI SNPs in CCRL2 are shown (see all 103    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs115744281,2
    C,F,H,--46446721(+) GAAGGT/ACATGC 1 -- us2k113Minor allele frequency- A:0.08NA NS EA CSA 1766
    rs1451383981,2
    --46446746(+) CAGGGC/TGATCC 1 -- us2k10--------
    rs115744291,2
    C,--46446810(+) GTTTTT/CACTTG 1 -- us2k12Minor allele frequency- C:0.24NA CSA 42
    rs1406612491,2
    --46446838(+) CATGAC/TTCTGT 1 -- us2k10--------
    rs1820117181,2
    --46446906(+) GTGTGC/TGTACT 1 -- us2k10--------
    rs1458256281,2
    --46447015(+) TTCAAC/GATCCT 1 -- us2k10--------
    rs1480026431,2
    --46447090(+) CTGTAA/GGGGGT 2 -- us2k10--------
    rs1416630221,2
    --46447123(+) ATGACA/CCCCAC 2 -- us2k10--------
    rs1501197491,2
    --46447254(+) GCACAA/CGTGGA 2 -- us2k10--------
    rs1860348671,2
    --46447326(+) ATAGTC/TCTCTC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for CCRL2 (46448654 - 46451014 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CCRL2: --
    Human Gene Mutation Database (HGMD): CCRL2

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CCRL2 for disorders           About GeneDecksing

    OMIM gene information: 608379    OMIM disorders: --

    6 diseases for CCRL2:    About MalaCards
    celiac disease    rheumatoid arthritis    hepatitis b    arthritis
    hepatitis    pneumonia

    Human Genome Epidemiology (HuGE) Navigator: CCRL2 (4 documents)

    Export disorders for CCRL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CCRL2 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with CCRL2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of a novel human chemokine receptor. (PubMed id 9473515)1, 2, 3 Fan P.... Li Y. (1998)
    2. Up-regulated expression and activation of the orphan chemokine receptor, CCRL2, in rheumatoid arthritis. (PubMed id 15188357)1, 2, 9 Galligan C.L....Yoshimura T. (2004)
    3. CCL19 is a specific ligand of the constitutively recy cling atypical human chemokine receptor CRAM-B. (PubMed id 20002784)1, 2, 9 Leick M....Burger M. (2010)
    4. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)1, 2 Muzny D.M....Gibbs R.A. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Human B cells express the orphan chemokine receptor CRAM-A/B in a maturation-stage-dependent and CCL5-modulated manner. (PubMed id 18397265)2, 9 Hartmann T.N....Burger M. (2008)
    7. Role of exonic variation in chemokine receptor genes on AIDS: CCRL2 F167Y association with pneumocystis pneumonia. (PubMed id 22046140)1 An P....Winkler C.A. (2011)
    8. Genome-wide association study implicates PARD3B-based AIDS restriction. (PubMed id 21502085)1 Troyer J.L....O'Brien S.J. (2011)
    9. Polymorphisms in innate immunity genes and patients r esponse to dendritic cell-based HIV immuno-treatment. (PubMed id 20056178)1 Segat L....Crovella S. (2010)
    10. Multiple common variants for celiac disease influenci ng immune gene expression. (PubMed id 20190752)1 Dubois P.C....van Heel D.A. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9034 HGNC: 1612 AceView: CCRL2 Ensembl:ENSG00000121797 euGenes: HUgn9034
    ECgene: CCRL2 H-InvDB: CCRL2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CCRL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CCRL2 gene:
    Search GeneIP for patents involving CCRL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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