CCR6 Gene
protein-coding GIFtS: 65
GCID: GC06P167525
|
|
chemokine (C-C motif) receptor 6
(Previous symbol: STRL22)
| |
Aliases
for CCR6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chemokine (C-C Motif) Receptor 61 2 | | CC-CKR-62 3 | | CMKBR61 2 3 5 | | CCR-62 3 | | GPR291 2 3 5 | | DRY62 3 | | CKR-L31 2 3 | | C-C CKR-62 3 | | STRL221 2 3 | | G-Protein Coupled Receptor 292 3 | | CKRL32 3 5 | | LARC Receptor2 3 | | GPRCY42 3 5 | | DRY-61 | | BN-11 2 | | C-C Chemokine Receptor Type 62 | | CD1961 2 | | Chemokine (C-C) Receptor 62 | | DCR21 2 | | G Protein-Coupled Receptor 292 | | GPR-CY41 3 | | Seven-Transmembrane Receptor, Lymphocyte, 222 | | Chemokine Receptor-Like 32 3 | | CD196 Antigen3 |
Export aliases for CCR6 gene to outside databasesPrevious GC identifers: GC06P166889 GC06P167409 GC06P167445 GC06P167383 GC06P164997 |
Summaries
for CCR6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CCR6:
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembraneprotein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells andmemory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptorhas been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulatethe migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternativelyspliced transcript variants that encode the same protein have been described for this gene. (provided by RefSeq, Jul2008)
UniProtKB/Swiss-Prot: CCR6_HUMAN, P51684Function: Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal byincreasing the intracellular calcium ions level
Gene Wiki entry for CCR6 (C-C chemokine receptor type 6)
|
Genomic Views
for CCR6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_025741.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCR6 gene promoter:
GR AML1a Pbx1a GR-beta FOXO4 GR-alpha Arnt
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCR6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCR6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q27 Ensembl cytogenetic band: 6q27 HGNC cytogenetic band: 6q27CCR6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P167525: view genomic region
(about GC identifiers)
Start:
|
167,525,295 bp from pter |
End:
|
167,553,184 bp from pter |
Size:
|
27,890 bases |
Orientation:
|
plus strand |
|
Proteins
for CCR6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CCR6_HUMAN, P51684 (See
protein sequence)Recommended Name: C-C chemokine receptor type 6 Size: 374 amino acids; 42494 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Caution: It is uncertain whether Met-1 or Met-6 is the initiator
Sequence caution: Sequence=CAB02144.1; Type=Erroneous initiation;
Secondary accessions: E1P5C6 P78553 Q92846Explore the universe of human proteins at neXtProt for CCR6: NX_P51684
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P51684
CCR6 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_004358.2 NP_113597.2
ENSEMBL proteins: ENSP00000343952 ENSP00000339393 ENSP00000383715 Reactome Protein details: P51684
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
CCR6 for ontologies About GeneDecksing
CCR6 Antibody Products:
Assay Products for CCR6: |
Protein
Domains /
Families
for CCR6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CCR6 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P51684ProtoNet protein and cluster: P51684 2 Blocks protein families: IPB000355 Chemokine receptor signature IPB004067 C-C chemokine receptor type 6 signature
UniProtKB/Swiss-Prot: CCR6_HUMAN, P51684Similarity: Belongs to the G-protein coupled receptor 1 family |
Function
for CCR6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CCR6_HUMAN, P51684Function: Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal byincreasing the intracellular calcium ions levelInduction: By IL2/interleukin-2 Genatlas biochemistry entry for CCR6:chemokine CC beta receptor,expressed in lymphocyte and monocyte,highly homolog to EBI1,IL8RA,IL8RB,G protein coupledreceptor superfamily
Clone
Products: |  | EMD Millipore Clones for the Expression of CCR6 | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCR6 (see all 10)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCR6 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CCR6 (NM_031409) | |  | Sino Biological Human cDNA Clone for CCR6 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCR6 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCR6 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCR6 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
CCR6 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for CCR6:
Animal Models:
Mouse knock-outs for CCR6: Ccr6tm1Lira Ccr6tm1Gma
6 MGI mutant phenotypes (inferred from 5 alleles ) (MGI details for Ccr6):
CCR6 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CCR6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/12 super-pathways (see all 12) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Class A/1 (Rhodopsin-like receptors) | | | 2 | Akt Signaling | | | 3 | Signaling by GPCR | | | 4 | Immune System | | | 5 | Beta defensins | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for CCR6
5/8 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CCR6 (see all 8)
2  BioSystems Pathways for CCR6
5/12 
Reactome Pathways for CCR6 (see all 12)
2 
Kegg Pathways (Kegg details for CCR6):
CCR6 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CCR6
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/187 Interacting proteins for CCR6 (P516843 ENSP000003393934) via UniProtKB, MINT, STRING, and/or I2D (see all 187)About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table
CCR6 for ontologies About GeneDecksing
|
Drugs & Compounds
for CCR6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CCR6 for compounds About GeneDecksing
 Browse Tocris compounds for CCR6
1 HMDB Compound for CCR6 About this table
8 Novoseek chemical compound relationships for CCR6 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| larc |
89.5 |
20 |
9169459 (4), 11120783 (3), 11035086 (1), 9365118 (1) (see all 11) |
| mip-3alpha |
88 |
4 |
18490742 (1), 17617631 (1) |
| rantes |
65.3 |
6 |
10679062 (2), 17133532 (1), 11994442 (1), 9169459 (1) |
| tarc |
42.8 |
2 |
9365118 (1), 9169459 (1) |
| ccl4 |
32.7 |
1 |
17133532 (1) |
| calcium |
9.12 |
4 |
9886385 (2), 10577517 (1), 16365449 (1) |
| lipid |
5.43 |
3 |
19928914 (2) |
| vegf |
5.24 |
2 |
15334073 (1), 16232215 (1) |
Search CenterWatch for drugs/clinical trials and news about CCR6
|
Transcripts
for CCR6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCR6 gene (2 alternative transcripts): NM_004367.5 NM_031409.3 Unigene Cluster for CCR6: Chemokine (C-C motif) receptor 6 Hs.46468 [show with all ESTs]Unigene Representative Sequence: NM_0314093 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000341935(uc003qvn.4 uc003qvm.4) ENST00000349984 ENST00000400926(uc003qvl.3 uc010kkm.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCR6 (see all 10)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCR6 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CCR6 (NM_031409) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCR6 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCR6 |
Additional cDNA sequence: AK223494.1 AK293015.1 AY242126.1 BC037960.1 U60000.1 U68030.1 U68031.1 5 DOTS entries: DT.121386105 DT.100749397 DT.95359744 DT.121386128 DT.432235 24/78 AceView cDNA sequences (see all 78): AA720658 BU193028 BM874378 AA292126 AI566733 BG289619 BC037960 NM_004367 BE550052 AY242126 NM_031409 AA884755 AW160364 AL043487 AI872081 AW404691 AA292127 AW627471 BP337163 BQ427775 BQ082444 BX279700 AI627284 BM999497
GeneLoc Exon Structure
|
Expression
for CCR6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCR6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAAAATGTGG
About this image
See CCR6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCR6
SOURCE GeneReport for Unigene cluster: Hs.46468
UniProtKB/Swiss-Prot: CCR6_HUMAN, P51684Tissue specificity: Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells butnot in natural killer cells, monocytes or granulocytes
SABiosciences Expression via Pathway-Focused PCR Arrays including CCR6 (see all 8):
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCR6
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CCR6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCR6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCR6 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCR6 |
Orthologs
for CCR6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CCR6 gene from 4/10 species (see all 10) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CCR61 |
chemokine (C-C motif) receptor 6 |
63.7(n)
60.06(a) |
|
769278 NM_001114081.1 NP_001107553.1 |
lizard
(Anolis carolinensis) |
Reptilia |
CCR66 |
-- |
54(a) |
1 ↔ 1 |
1(225500770-225501873) |
zebrafish
(Danio rerio) |
Actinopterygii |
ccr6a1 |
chemokine (C-C motif) receptor 6a |
55.68(n)
46.48(a) |
|
558616 NM_001099991.1 NP_001093461.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.152852 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
80.46(n) |
|
AK120580.1 |
ENSEMBL Gene Tree for CCR6 (if available)
TreeFam Gene Tree for CCR6 (if available) |
Paralogs
for CCR6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CCR6 gene
- CCR52 CXCR62 CXCR32 XCR12 CCR92 CCBP22 CCRL22 CCR72
- CX3CR12 CCR82 CXCR22 CCRL12 CCR42 CXCR12 CCR12 CCR22
- CXCR52 CCR102 CCR32 CXCR42
18/35 SIMAP similar genes for CCR6 using alignment to 1 protein entry: CCR6_HUMAN(see all similar genes):CXCR1 CCR4 CXCR2 IL8RB CCR7 CCR2
CCR5 CCR8 CCR10 CCR9 CCBP2 AGTR1
CCR1 CCR3 CCRL1 CXCR4 BLR1 CXCR3
CCR6 for paralogs About GeneDecksing
|
Genomic Variants
for CCR6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCR6 (167525295 - 167553184 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for CCR6
5 CNVs: 94209 8538 64715 2098 3653
3 Indels: 94210 81730 33826
Human Gene Mutation Database (HGMD): CCR6
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCR6 |
|
Disorders
/ Diseases
for CCR6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CCR6 for disorders About GeneDecksing
OMIM gene information: 601835
OMIM disorders: --
20/60  diseases for CCR6 (see all 60): About MalaCardserdheim-chester disease b-cell non-hodgkin lymphoma langerhans-cell histiocytosis non-hodgkin lymphoma
chronic obstructive pulmonary disease hodgkin's lymphoma ankylosing spondylitis squamous cell carcinoma of the head and neck
systemic lupus erythematosus squamous cell carcinoma lupus erythematosus histiocytosis
inflammatory bowel disease atopic dermatitis rheumatoid arthritis pulmonary sarcoidosis
ulcerative colitis insulin resistance kaposi's sarcoma spondylitis
2 diseases from the University of Copenhagen DISEASES database for CCR6:Rheumatoid arthritis Psoriasis 10/28 Novoseek disease relationships for CCR6 gene (see all 28) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| rheumatoid arthritis |
42.7 |
8 |
20453841 (3), 12695561 (2), 16207316 (1) |
| inflammation |
41.7 |
7 |
16215992 (2), 17379855 (1), 19928914 (1), 17178254 (1) (see all 5) |
| necrosis |
41.5 |
2 |
19295614 (1), 11090084 (1) |
| psoriasis |
38.9 |
7 |
15315355 (3), 10843722 (1), 15550147 (1), 19659772 (1) |
| b-all |
36.7 |
1 |
11368435 (1) |
| skin lesion |
29 |
2 |
15315355 (1), 19659772 (1) |
| tumors |
27.6 |
19 |
18465142 (4), 16622267 (3), 15334073 (1), 19340288 (1) (see all 12) |
| autoimmunity |
26 |
2 |
20453841 (1), 18706444 (1) |
| lymphoma |
20.7 |
3 |
12514792 (2), 11368435 (1) |
| lymphoproliferative disorders |
19.8 |
3 |
12614207 (1), 15621766 (1), 11368435 (1) |
Human Genome Epidemiology (HuGE) Navigator: CCR6 (20 documents)
Export disorders for CCR6 gene to outside databases
|
Publications
for CCR6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCR6 gene, integrated from 9 sources (see all 269):
(articles sorted by number of sources associating them with CCR6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and RNA expression of two new human chemokine receptor-like genes. (PubMed id 8886020)1, 2, 3, 9 Zaballos A.... Marquez G. (1996)
- Identification of CCR6, the specific receptor for a novel lymphocyte- directed CC chemokine LARC. (PubMed id 9169459)1, 2, 9 Baba M.... Yoshie O. (1997)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Cloning of STRL22, a new human gene encoding a G-protein-coupled receptor related to chemokine receptors and located on chromosome 6q27. (PubMed id 9070937)1, 2 Liao F.... Farber J.M. (1997)
- Chemokine receptor CCR6 expression level and liver metastases in colorectal cancer. (PubMed id 16622267)1, 9 Ghadjar P....Keilholz U. (2006)
- Chemokine receptor CCR6 expression level and aggressiveness of prostate cancer. (PubMed id 18465142)1, 9 Ghadjar P....Keilholz U. (2008)
- Molecular characterization of CCR6: involvement of multiple domains in ligand binding and receptor signaling. (PubMed id 15591779)1, 9 Ai L.S....Liao F. (2004)
- CCR6 colocalizes with CD18 and enhances adhesion to activated endothelial cells in CCR6-transduced Jurkat T cells. (PubMed id 12193700)1, 9 Maki W....Hwang S.T. (2002)
- CCR6 is a functional chemokine receptor that serves to identify select B-cell non-Hodgkin's lymphomas. (PubMed id 12514792)1, 9 Rodig S.J....Dorfman D.M. (2002)
|
External Searches for CCR6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCR6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCR6 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCR6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCR6 | Pharmacogenomics, SNPs, Pathways | | Wikipedia | http://en.wikipedia.org/wiki/CC_chemokine_receptors |
|
| | |
About This Section
| Patent Information for CCR6 gene:
Search GeneIP for patents involving CCR6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCR6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CCR6 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCR6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCR6 | | | OriGene Protein Over-expression Lysate for CCR6 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCR6 | | OriGene 3'-UTR Clone for CCR6 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCR6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCR6 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCR6 | | OriGene Custom Protein Services for CCR6 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCR6 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCR6 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCR6 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCR6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCR6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCR6 |
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| | | | Search Tocris compounds for CCR6 |
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 | | | CCR6 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCR6 |
|  |  |  | | | | ThermoFisher Antibodies for CCR6 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCR6 |
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