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Aliases for CCNYL2 Gene

Aliases for CCNYL2 Gene

  • Cyclin Y-Like 2 (Pseudogene) 2 3 5
  • C10orf21 3 4
  • Chromosome 10 Open Reading Frame 21 2
  • Cyclin-Y-Like Protein 2 3
  • Cyclin Y-Like 2 2
  • BA178A10.2 3
  • CCNYL2P 3

External Ids for CCNYL2 Gene

Previous HGNC Symbols for CCNYL2 Gene

  • C10orf21

Previous GeneCards Identifiers for CCNYL2 Gene

  • GC10M042225
  • GC10M042903
  • GC10M039430
  • GC10M042418
  • GC10M042421
  • GC10M042423
  • GC10M042426

Summaries for CCNYL2 Gene

GeneCards Summary for CCNYL2 Gene

CCNYL2 (Cyclin Y-Like 2 (Pseudogene)) is a Pseudogene. GO annotations related to this gene include protein kinase binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCNYL2 Gene

Genomics for CCNYL2 Gene

Regulatory Elements for CCNYL2 Gene

Enhancers for CCNYL2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F042826 0.6 ENCODE 3.9 -352.0 -351999 1.4 CTCF KLF1 RFX1 PKNOX1 BMI1 RAD21 POLR2A ZNF512 TARDBP LOC441666 CCNYL2 RNU6-885P PIR61313
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCNYL2 on UCSC Golden Path with GeneCards custom track

Promoters for CCNYL2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001422859 -752 1399 CTCF ZNF223 IRF3 SIN3A MAX ZIC2 GLIS2 POLR2A PATZ1 SCRT2

Genomic Location for CCNYL2 Gene

Chromosome:
10
Start:
42,408,168 bp from pter
End:
42,475,349 bp from pter
Size:
67,182 bases
Orientation:
Minus strand

Genomic View for CCNYL2 Gene

Genes around CCNYL2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCNYL2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCNYL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCNYL2 Gene

Proteins for CCNYL2 Gene

  • Protein details for CCNYL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T2Q4-CCYL2_HUMAN
    Recommended name:
    Cyclin-Y-like protein 2
    Protein Accession:
    Q5T2Q4

    Protein attributes for CCNYL2 Gene

    Size:
    361 amino acids
    Molecular mass:
    41278 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI12446.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for CCNYL2 Gene

Post-translational modifications for CCNYL2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCNYL2 Gene

Domains & Families for CCNYL2 Gene

Gene Families for CCNYL2 Gene

Protein Domains for CCNYL2 Gene

Suggested Antigen Peptide Sequences for CCNYL2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5T2Q4

UniProtKB/Swiss-Prot:

CCYL2_HUMAN :
  • Contains 1 cyclin N-terminal domain.
  • Belongs to the cyclin family. Cyclin Y subfamily.
Domain:
  • Contains 1 cyclin N-terminal domain.
Family:
  • Belongs to the cyclin family. Cyclin Y subfamily.
genes like me logo Genes that share domains with CCNYL2: view

Function for CCNYL2 Gene

Gene Ontology (GO) - Molecular Function for CCNYL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0019901 protein kinase binding IEA --
genes like me logo Genes that share ontologies with CCNYL2: view

Phenotypes for CCNYL2 Gene

genes like me logo Genes that share phenotypes with CCNYL2: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCNYL2 Gene

Localization for CCNYL2 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCNYL2 gene
Compartment Confidence
extracellular 1
mitochondrion 1
peroxisome 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCNYL2 Gene

Pathways & Interactions for CCNYL2 Gene

SuperPathways for CCNYL2 Gene

No Data Available

Interacting Proteins for CCNYL2 Gene

Gene Ontology (GO) - Biological Process for CCNYL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity IEA --
genes like me logo Genes that share ontologies with CCNYL2: view

No data available for Pathways by source and SIGNOR curated interactions for CCNYL2 Gene

Transcripts for CCNYL2 Gene

mRNA/cDNA for CCNYL2 Gene

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CCNYL2 Gene

No ASD Table

Relevant External Links for CCNYL2 Gene

GeneLoc Exon Structure for
CCNYL2
ECgene alternative splicing isoforms for
CCNYL2

Expression for CCNYL2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CCNYL2 Gene

mRNA differential expression in normal tissues according to GTEx for CCNYL2 Gene

This gene is overexpressed in Testis (x25.8).

Protein differential expression in normal tissues from HIPED for CCNYL2 Gene

This gene is overexpressed in Pancreas (51.3) and Brain (17.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCNYL2 Gene



Protein tissue co-expression partners for CCNYL2 Gene

NURSA nuclear receptor signaling pathways regulating expression of CCNYL2 Gene:

CCNYL2
genes like me logo Genes that share expression patterns with CCNYL2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CCNYL2 Gene

Orthologs for CCNYL2 Gene

Evolution for CCNYL2 Gene

ENSEMBL:
Gene Tree for CCNYL2 (if available)
TreeFam:
Gene Tree for CCNYL2 (if available)

No data available for Orthologs for CCNYL2 Gene

Paralogs for CCNYL2 Gene

(8) SIMAP similar genes for CCNYL2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CCNYL2: view

No data available for Paralogs for CCNYL2 Gene

Variants for CCNYL2 Gene

Sequence variations from dbSNP and Humsavar for CCNYL2 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs10508867 -- 42,461,021(+) CCATC(A/G)GAAGA intron-variant
rs10561381 -- 42,465,292(+) ACACA(-/CACACA)TACAC intron-variant
rs10900177 -- 42,409,609(+) GACTG(C/T)TCCTA nc-transcript-variant
rs10900184 -- 42,412,563(+) TGATT(A/G)TGGCA intron-variant
rs10900188 -- 42,414,247(+) TGTGT(A/G)TATAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCNYL2 Gene

Variant ID Type Subtype PubMed ID
nsv947881 CNV duplication 23825009
nsv947880 CNV duplication 23825009
nsv825348 CNV loss 20364138
nsv550680 CNV loss 21841781
nsv550672 CNV gain 21841781
nsv471665 CNV gain 15918152
nsv470932 CNV gain 18288195
nsv469725 CNV gain 16826518
nsv466877 CNV gain 19166990
nsv433411 CNV gain 18776910
nsv1119805 CNV deletion 24896259
nsv1051346 CNV gain 25217958
nsv1042764 CNV gain 25217958
esv3891795 CNV gain 25118596
esv3891791 CNV gain 25118596
esv3891790 CNV gain 25118596
esv3891789 CNV gain 25118596
esv3623011 CNV loss 21293372
esv3623008 CNV gain 21293372
esv3623007 CNV loss 21293372
esv3623002 CNV gain 21293372
esv3576449 CNV gain 25503493
esv3428772 CNV duplication 20981092
esv2759746 CNV loss 17122850
esv2328272 CNV deletion 18987734
dgv79n27 CNV gain 19166990
dgv78n27 CNV gain 19166990
dgv719n100 CNV gain 25217958
dgv113e214 CNV gain 21293372
dgv1103n54 CNV gain 21841781
dgv1102n54 CNV gain 21841781
dgv1098n54 CNV gain 21841781
dgv1097n54 CNV gain 21841781

Relevant External Links for CCNYL2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCNYL2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CCNYL2 Gene

Disorders for CCNYL2 Gene

Relevant External Links for CCNYL2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCNYL2

No disorders were found for CCNYL2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCNYL2 Gene

Publications for CCNYL2 Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 4 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for CCNYL2 Gene

Sources for CCNYL2 Gene

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