Aliases for CCNY Gene
External Ids for CCNY Gene
Previous Symbols for CCNY Gene
Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 [PubMed 18060517]).[supplied by OMIM, May 2009]
GeneCards Summary for CCNY Gene
CCNY (Cyclin Y) is a Protein Coding gene. GO annotations related to this gene include protein kinase binding and cyclin-dependent protein serine/threonine kinase regulator activity. An important paralog of this gene is CCNYL1.
UniProtKB/Swiss-Prot for CCNY Gene
Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.