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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CCNL2 Gene

protein-coding   GIFtS: 45
GCID: GC01M001321

cyclin L2

(Previous name: cyclin M )
(Previous symbol: CCNM)
 Explore 5 diseases affiliated with
CCNL2 via our new
 Human Malady Compendium 
Biological research products
for CCNL2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Cyclin L21 2     Paneth Cell-Enhanced Expression Protein2 3
CCNM1 2     Ania-6b1
HLA-ISO1 2     ANIA-6B2
PCEE1 2     HCLA-ISO2
SB1381 2     Cyclin-L21
Cyclin M1 2     

External Ids:    HGNC: 205701   Entrez Gene: 816692   Ensembl: ENSG000002219787   OMIM: 6134825   UniProtKB: Q96S943   

Export aliases for CCNL2 gene to outside databases

Previous GC identifers: GC01M001073 GC01M001247 GC01M001276 GC01P9A0164 GC01P8D0164 GC01M001312 GC01M000593


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CCNL2:
The protein encoded by this gene belongs to the cyclin family. Through its interaction with several proteins, such as
RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the
pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and
antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for
this gene. (provided by RefSeq, Aug 2011)

UniProtKB/Swiss-Prot: CCNL2_HUMAN, Q96S94
Function: Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Also modulates the
expression of critical apoptotic factor, leading to cell apoptosis

Gene Wiki entry for CCNL2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004350.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CCNL2 gene promoter:
         NCX/Ncx   MyoD   Lmo2   Tal-1beta   Gfi-1   E47   POU2F1   POU2F1a   c-Myc   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for CCNL2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCNL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.33   Ensembl cytogenetic band:  1p36.33   HGNC cytogenetic band: 1p36.33

CCNL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCNL2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M001321:  view genomic region     (about GC identifiers)

Start:
1,321,091 bp from pter      End:
1,334,718 bp from pter
Size:
13,628 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CCNL2_HUMAN, Q96S94 (See protein sequence)
Recommended Name: Cyclin-L2  
Size: 520 amino acids; 58147 Da
Subunit: Interacts with CDK11A, CDK11B, CDK12, CDK13, SFRS2, SFRS7 and POLR2A, the hyperphosphorylated C-terminal
domain (CTD) of RNA polymerase II
Subcellular location: Nucleus speckle
Sequence caution: Sequence=AAH71622.2; Type=Erroneous initiation; Sequence=BAB84938.1; Type=Erroneous initiation;
Secondary accessions: A8K8A3 B1B152 Q5T2N5 Q5T2N6 Q6IQ12 Q7Z4Z8 Q8N3C9 Q8N3D5 Q8NHE3 Q8TEL0 Q96B00
Alternative splicing: 3 isoforms:  Q96S94-1   Q96S94-2   Q96S94-3   (Ref.1 (AAM76789) sequence is in conflict in position: 226:K->IT)

Explore the universe of human proteins at neXtProt for CCNL2: NX_Q96S94

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96S94

  • CCNL2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001034666.1  NP_112199.2  

    ENSEMBL proteins: 
     ENSP00000462056   ENSP00000383611   ENSP00000423734   ENSP00000424647   ENSP00000386158  
     ENSP00000392899   ENSP00000464685   ENSP00000386132  

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    Uscn Proteins for CCNL2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA17494991
    GO:0016607nuclear speck IEA--


    CCNL2 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CCNL2 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR013763 Cyclin-like
     IPR006671 Cyclin_N
     IPR004367 Cyclin_C
     IPR017060 Cyclin_L
     IPR015429 Cyclin_C/H/T/L

    Graphical View of Domain Structure for InterPro Entry Q96S94

    ProtoNet protein and cluster: Q96S94

    1 Blocks protein family: IPB006670 Cyclin

    UniProtKB/Swiss-Prot: CCNL2_HUMAN, Q96S94
    Domain: Contains a RS region (arginine-serine dipeptide repeat) within the C-terminal domain which is the hallmark of
    the SR family of splicing factors. This region probably plays a role in protein-protein interactions (By similarity)
    Similarity: Belongs to the cyclin family. Cyclin L subfamily


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CCNL2_HUMAN, Q96S94
    Function: Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Also modulates the
    expression of critical apoptotic factor, leading to cell apoptosis

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    hsa-miR-596 hsa-miR-3194-5p hsa-miR-200a hsa-miR-29a hsa-miR-578 hsa-miR-138-2* hsa-miR-141 hsa-miR-548m
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCNL2

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0019901protein kinase binding IEA--


    CCNL2 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CCNL2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/8 Interacting proteins for CCNL2 (Q96S943 ENSP000003836114) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DYRK1AQ136273, ENSP000003819324I2D: score=2 STRING: ENSP00000381932
    POLR2AP249283, ENSP000003149494I2D: score=2 STRING: ENSP00000314949
    SRSF2Q011303, ENSP000003508774I2D: score=1 STRING: ENSP00000350877
    SRSF7Q166293, ENSP000003259054I2D: score=1 STRING: ENSP00000325905
    CDK11AQ9UQ883, ENSP000003844424I2D: score=1 STRING: ENSP00000384442
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000079regulation of cyclin-dependent protein kinase activity IEA--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0006396RNA processing IEA--


    CCNL2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CCNL2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CCNL2
    1 Novoseek chemical compound relationship for CCNL2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    arginine 43.9 3 14623875 (2), 17494991 (1)

    Search CenterWatch for drugs/clinical trials and news about CCNL2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CCNL2 gene (4 alternative transcripts): 
    NM_001039577.3  NM_030937.4  NM_001144867.1  NM_001144868.1  

    Unigene Cluster for CCNL2:

    Cyclin L2
    Hs.515704  [show with all ESTs]
    Unigene Representative Sequence: NM_030937
    18/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000480479(uc010nym.1 uc001afg.1 uc001afi.2 uc001afj.2)
    ENST00000482621 ENST00000463260 ENST00000400809 ENST00000496007(uc001aff.1 uc021oep.1)
    ENST00000482365 ENST00000481223 ENST00000418865 ENST00000505849 ENST00000488340
    ENST00000492998 ENST00000469113 ENST00000480646 ENST00000471930 ENST00000408918
    ENST00000473872 ENST00000425598 ENST00000463895

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    8/52 QIAGEN miScript miRNA Assays for microRNAs that regulate CCNL2 (see all 52):
    hsa-miR-596 hsa-miR-3194-5p hsa-miR-200a hsa-miR-29a hsa-miR-578 hsa-miR-138-2* hsa-miR-141 hsa-miR-548m
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    Additional cDNA sequence: 

    AF087903.1 AF251294.1 AK000685.1 AK026796.1 AK027770.1 AK056120.1 AK057133.1 AK225758.1 
    AK292268.1 AK293451.1 AL834432.1 AL834441.1 AY037150.1 BC016333.1 BC071622.1 

    24/40 DOTS entries (see all 40):

    DT.100649805  DT.91757120  DT.86780790  DT.99932236  DT.100757555  DT.121375226  DT.91866937  DT.101984606 
    DT.100827562  DT.97860614  DT.97811707  DT.121375185  DT.121375220  DT.121375124  DT.95161912  DT.101984605 
    DT.121375107  DT.121375134  DT.121375227  DT.121375188  DT.95161913  DT.95161932  DT.121375097  DT.121375132 

    24/187 AceView cDNA sequences (see all 187):

    BX422194 BE252968 BG764130 BQ707313 AI391702 AI568921 BU190459 AW197323 
    AI797782 BG481188 BM263342 AW005434 AI935233 CB216259 AI245711 AI312749 
    BU682875 BM791839 AW150352 AI335583 BM836041 AI700009 BU948748 AI183424 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CCNL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGTTTAATAC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See CCNL2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CCNL2

    SOURCE GeneReport for Unigene cluster: Hs.515704

    UniProtKB/Swiss-Prot: CCNL2_HUMAN, Q96S94
    Tissue specificity: Ubiquitously expressed, with a higher expression level observed in ovary, heart, liver and pancreas

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CCNL2 gene from 7/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves CCNL21 cyclin L2 74.58(n)
    82.82(a)
      395124  NM_204470.2  NP_989801.2 
    lizard
    (Anolis carolinensis)
    Reptilia CCNL26
    --
    74(a)
    1 ↔ 1
    GL343701.1(53344-66259)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.165422 Xenopus laevis transcribed sequence with moderate similarity more 78.95(n)    BQ727551.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG169036
    --
    36(a)
    1 → many
    X(1972376-1974438)
    worm
    (Caenorhabditis elegans)
    Secernentea cyl-16
    CYclin L family member (cyl-1)
    33(a)
    1 → many
    V(11990991-11993748)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons RCY16
    cyclin-L1-1
    30(a)
    1 → many
    2(11243219-11246035)
    rice
    (Oryza sativa)
    Liliopsida --
    cyclin-L1-1, putative, expressed
    33(a)
    1 → many
    1(15617195-15623540)


    ENSEMBL Gene Tree for CCNL2 (if available)
    TreeFam Gene Tree for CCNL2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CCNL2 gene
    CCNT22  CCNK2  CCNC2  CCNL12  CCNT12  FAM58A2  
    3 SIMAP similar genes for CCNL2 using alignment to 5 protein entries:     CCNL2_HUMAN (see all proteins):
    CCNL1    FAM58A    CYCT1b

    CCNL2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CCNL2
    PGOHUM00000263127


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/297 NCBI SNPs in CCNL2 are shown (see all 297    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1829596361,2
    --1320591(+) CCCGGC/GTTCAA 1 -- ds50010--------
    rs1121977111,2
    C,--1320616(+) TCAGCC/TTCCTG 1 -- ds50011Minor allele frequency- T:0.50WA 2
    rs1410938261,2
    --1320621(+) CTCCTC/GAGTAG 1 -- ds50010--------
    rs1858365491,2
    --1320737(+) GATCCA/GCCTGC 1 -- ds50010--------
    rs49704441,2
    C,F,A,--1320764(+) GCTGGA/GATTAC 1 -- ds50018Minor allele frequency- G:0.12NA WA CSA 17
    rs1902091091,2
    --1320774(+) CAGGCA/GTAAGC 1 -- ds50010--------
    rs288336211,2
    C--1320907(-) GCTCAG/CGCCTG 1 -- ds50011Minor allele frequency- C:0.50NA 2
    rs96612881,2
    C,--1320933(-) AGCGCT/CGTGGG 1 -- ds50014Minor allele frequency- C:0.00NA 10
    rs1824934081,2
    --1321007(+) ACCGCA/GCCCGG 1 -- ds50010--------
    rs1449939491,2
    --1321090(+) AAAATC/TTGGCC 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for CCNL2 (1321091 - 1334718 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for CCNL2
         2 CNVs: 30362 3276

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CCNL2 for disorders           About GeneDecksing

    OMIM gene information: 613482    OMIM disorders: --

    5 diseases for CCNL2:    About MalaCards
    embryonal carcinoma    hepatocellular carcinoma    lung cancer    carcinoma
    malaria

    1 Novoseek disease relationship for CCNL2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 2 14684736 (2)


    Export disorders for CCNL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CCNL2 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with CCNL2)
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    1. Cyclin L2, a novel RNA polymerase II-associated cyclin, is involved in pre-mRNA splicing and induces apoptosis of human hepatocellular carcinoma cells. (PubMed id 14684736)1, 2, 9 Yang L.... Cao X. (2004)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors. (PubMed id 14623875)1, 9 de Graaf K....Becker W. (2004)
    6. Characterization of cyclin L1 as an immobile component of the splicing factor compartment. (PubMed id 17494991)1, 9 Herrmann A....Becker W. (2007)
    7. The Brd4 extraterminal domain confers transcription a ctivation independent of pTEFb by recruiting multiple proteins, including NSD3. (PubMed id 21555454)1 Rahman S....Howley P.M. (2011)
    8. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    9. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 81669 HGNC: 20570 AceView: CCNL2 Ensembl:ENSG00000221978 euGenes: HUgn81669
    ECgene: CCNL2 H-InvDB: CCNL2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CCNL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CCNL2 gene:
    Search GeneIP for patents involving CCNL2

    GeneCards and IP:
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