CCNJL Gene
protein-coding GIFtS: 43
GCID: GC05M159678
|
|
cyclin J-like
| |
Aliases
for CCNJL gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cyclin J-Like1 2 | | FLJ141661 | | Cyclin-J-Like Protein2 |
Export aliases for CCNJL gene to outside databasesPrevious GC identifers: GC05M159612 GC05M154772 |
Summaries
for CCNJL gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCNJL gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_023133.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCNJL gene promoter:
AhR NF-1/L NF-1 Elk-1 RelA CUTL1 c-Ets-1 AREB6 HSF2 ARP-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCNJL
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCNJL |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q33.3 Ensembl cytogenetic band: 5q33.3 HGNC cytogenetic band: 5q33.3CCNJL Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M159678: view genomic region
(about GC identifiers)
Start:
|
159,678,659 bp from pter |
End:
|
159,772,403 bp from pter |
Size:
|
93,745 bases |
Orientation:
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minus strand |
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Proteins
for CCNJL gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CCNJL_HUMAN, Q8IV13 (See
protein sequence)Recommended Name: Cyclin-J-like protein Size: 435 amino acids; 48406 Da
Caution: It is uncertain whether Met-1 or Met-2 is the initiator
Sequence caution: Sequence=AAH13353.1; Type=Erroneous initiation; Sequence=BAB14856.1; Type=Erroneous initiation;
Secondary accessions: Q6ZN43 Q9H7W8Alternative splicing: 2 isoforms: Q8IV13-1 Q8IV13-2 Explore the universe of human proteins at neXtProt for CCNJL: NX_Q8IV13
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IV13
CCNJL Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_078841.3
ENSEMBL proteins: ENSP00000377547 ENSP00000257536 ENSP00000427960 ENSP00000428836 ENSP00000446367 ENSP00000444778
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
CCNJL for ontologies About GeneDecksing
CCNJL Antibody Products:
Assay Products for CCNJL: |
Protein
Domains /
Families
for CCNJL gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CCNJL for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IV13ProtoNet protein and cluster: Q8IV13 1 Blocks protein family: IPB006670 Cyclin
UniProtKB/Swiss-Prot: CCNJL_HUMAN, Q8IV13Similarity: Belongs to the cyclin family. Cyclin J subfamilySimilarity: Contains 1 cyclin N-terminal domain |
Function
for CCNJL gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCNJL
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCNJL (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: CCNJL (NM_024565) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCNJL |
|
Pathways & Interactions
for CCNJL gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCNJL
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
4 Interacting proteins for CCNJL (Q8IV133 ENSP000003775474) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for CCNJL gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCNJL
Search CenterWatch for drugs/clinical trials and news about CCNJL
|
Transcripts
for CCNJL gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCNJL gene: NM_024565.5 Unigene Cluster for CCNJL: Cyclin J-like Hs.14070 [show with all ESTs]Unigene Representative Sequence: NM_0245659 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000393977(uc003lyb.1 uc011dee.1) ENST00000377503(uc003lyc.1)
ENST00000257536(uc011def.1) ENST00000519673 ENST00000520748 ENST00000518764
ENST00000521643 ENST00000541762 ENST00000505287
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCNJL
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCNJL (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CCNJL (NM_024565) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCNJL | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCNJL |
Additional cDNA sequence: AK024228.1 AK294000.1 AK302823.1 BC013353.2 BC035871.1 4 DOTS entries: DT.440792 DT.95138072 DT.92017482 DT.40189495 24/55 AceView cDNA sequences (see all 55): BM701110 AW025049 AA355535 BC013353 AI139936 NM_024565 AK131381 AA894965 BM981490 C01507 BM715897 BC035871 AU126411 AI024927 BF111450 AW264676 BE797409 BE793555 BM051160 BE895628 BG764802 AI024934 AK024228 AA005221
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for CCNJL About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b |
|---|
|
| SP1: | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | - | | | | | | |
| SP3: | | | | | - | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CCNJL
|
Expression
for CCNJL gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCNJL expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGACAGTAA
About this image
See CCNJL Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCNJL
SOURCE GeneReport for Unigene cluster: Hs.14070
SABiosciences Custom PCR Arrays for CCNJL
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCNJL
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CCNJL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCNJL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCNJL | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCNJL |
Orthologs
for CCNJL gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CCNJL gene from 4/11 species (see all 11) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
F1NSC0_CHICK6 |
Uncharacterized protein |
50(a) |
1 ↔ 1 |
13(7611456-7630075) |
lizard
(Anolis carolinensis) |
Reptilia |
CCNJL6 |
-- |
47(a) |
1 ↔ 1 |
GL343286.1(1164643-1172431) |
zebrafish
(Danio rerio) |
Actinopterygii |
CU855895.26 |
-- |
46(a) |
1 ↔ 1 |
21(28798829-28825696) |
fruit fly
(Drosophila melanogaster) |
Insecta |
CycJ6 |
Cyclin J |
19(a) |
1 → many |
3L(3466414-3468098) |
Species with no ortholog for CCNJL
ENSEMBL Gene Tree for CCNJL (if available)
TreeFam Gene Tree for CCNJL (if available) |
Paralogs
for CCNJL gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CCNJL gene
- CCNJ2
11 SIMAP similar genes for CCNJL using alignment to 5 protein entries: CCNJL_HUMAN (see all proteins):C12orf76 NCKAP1L SH2B3 SNRPF MST132 COQ5
KIAA1651 CCNJ PFKFB3 TUBA1C ATF1
CCNJL for paralogs About GeneDecksing
|
Genomic Variants
for CCNJL gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCNJL (159678659 - 159772403 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CCNJL
1 CNV: 51607 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCNJL |
|
Disorders
/ Diseases
for CCNJL gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for CCNJL gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCNJL gene integrated from 9 sources:
(articles sorted by number of sources associating them with CCNJL) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for CCNJL gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCNJL gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCNJL gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCNJL gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCNJL | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CCNJL gene:
Search GeneIP for patents involving CCNJL
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCNJL gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CCNJL | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCNJL | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCNJL | | | OriGene Protein Over-expression Lysate for CCNJL | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCNJL | | OriGene 3'-UTR Clone for CCNJL | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCNJL | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCNJL | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CCNJL | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCNJL |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCNJL |
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