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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CCNDBP1 Gene

protein-coding   GIFtS: 51
GCID: GC15P043477

Cyclin D-Type Binding-Protein 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Cyclin D-Type Binding-Protein 11 2     HHM2 3
GCIP2 3 5     Grap2 Cyclin Interacting Protein1
D-Type Cyclin-Interacting Protein 11 2     HHM Protein1
Grap2 And Cyclin-D-Interacting Protein2 3     MAID Protein1
Human Homolog Of Maid2 3     Cyclin-D1-Binding Protein 12
DIP12 3     

External Ids:    HGNC: 15871   Entrez Gene: 235822   Ensembl: ENSG000001669467   OMIM: 6070895   UniProtKB: O952733   
ORGUL members:         
NONCODE14:n407929      

Export aliases for CCNDBP1 gene to outside databases

Previous GC identifers: GC15P038845 GC15P036373 GC15P041057 GC15P041193 GC15P041264 GC15P020326


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CCNDBP1 Gene:
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein
important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D.
Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin
D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to
interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene
expression. Several alternatively spliced variants have been found for this gene. (provided by RefSeq, Apr 2009)

GeneCards Summary for CCNDBP1 Gene: 
CCNDBP1 (cyclin D-type binding-protein 1) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with CCNDBP1 include optic disk drusen, and congenital dyserythropoietic anemia type i. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: CCDB1_HUMAN, O95273
Function: May negatively regulate cell cycle progression. May act at least in part via inhibition of the
cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription

Gene Wiki entry for CCNDBP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.2  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CCNDBP1 gene promoter:
         STAT5B   NF-kappaB1   NF-kappaB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCNDBP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CCNDBP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCNDBP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q14-q15   Ensembl cytogenetic band:  15q15.2   HGNC cytogenetic band: 15q14-q15

CCNDBP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCNDBP1 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P043477:  view genomic region     (about GC identifiers)

Start:
43,477,316 bp from pter      End:
43,488,229 bp from pter
Size:
10,914 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CCDB1_HUMAN, O95273 (See protein sequence)
Recommended Name: Cyclin-D1-binding protein 1  
Size: 360 amino acids; 40262 Da
Subunit: Interacts with CCND1 and GRAP2. May also interact with COPS5, RPLP0, SIRT6, SYF2 and TCF3
Subcellular location: Cytoplasm. Nucleus
Developmental stage: Expression may increase during differentiation
Sequence caution: Sequence=AAD11777.1; Type=Frameshift; Positions=8, 14, 18; Sequence=AAP97163.1; Type=Frameshift;
Positions=17, 40;
1 PDB 3D structure from and Proteopedia for CCNDBP1:
3AY5 (3D)    
Secondary accessions: A8K3Q0 A8K3U2 Q6ZQN9 Q7Z519 Q8NBS7 Q8NBY2 Q9NS19 Q9NYH3 Q9UHX9
Alternative splicing: 4 isoforms:  O95273-1   O95273-2   O95273-3   O95273-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CCNDBP1: NX_O95273

Explore proteomics data for CCNDBP1 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylated
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O95273

  • CCNDBP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CCNDBP1 Protein Expression
    REFSEQ proteins: NP_036274.3  
    ENSEMBL proteins: 
     ENSP00000300213   ENSP00000456797   ENSP00000456839   ENSP00000455687   ENSP00000457611  
     ENSP00000456041   ENSP00000455419   ENSP00000454420   ENSP00000349047  

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    Cloud-Clone Corp. Proteins for CCNDBP1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA12437976
    GO:0005737cytoplasm IEA--

    CCNDBP1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026907 CCNDBP1

    Graphical View of Domain Structure for InterPro Entry O95273

    ProtoNet protein and cluster: O95273

    UniProtKB/Swiss-Prot: CCDB1_HUMAN, O95273
    Similarity: Belongs to the CCNDBP1 family


    CCNDBP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CCDB1_HUMAN, O95273
    Function: May negatively regulate cell cycle progression. May act at least in part via inhibition of the
    cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription
    Induction: Expression is induced by sodium butyrate, an inhibitor of colon cancer cell proliferation

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI10915743
         
    CCNDBP1 for ontologies           About GeneDecksing


    Phenotypes:
         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ccndbp1):
     behavior/neurological  cellular  embryogenesis  liver/biliary system  tumorigenesis 

    CCNDBP1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Ccndbp1tm1Drmr for CCNDBP1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CCNDBP1 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCNDBP1 
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    SwitchGear 3'UTR luciferase reporter plasmidCCNDBP1 3' UTR sequence
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCNDBP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CCNDBP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/25 Interacting proteins for CCNDBP1 (O952731, 2, 3 ENSP000003002134) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COPS5Q929051, 3, ENSP000003505124EBI-748961,EBI-594661 I2D: score=1 STRING: ENSP00000350512
    ID2Q023632MINT-8396328 MINT-8396313 MINT-8396281 MINT-8396356
    CCND1P243852, 3, ENSP000002275074MINT-8396267 I2D: score=2 STRING: ENSP00000227507
    OLIG1Q8TAK62, 3, ENSP000003310664MINT-8396226 I2D: score=1 STRING: ENSP00000331066
    MRPS9P829332, 3, ENSP000002584554MINT-64674 I2D: score=4 STRING: ENSP00000258455
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007049cell cycle IEA--
    GO:0051726regulation of cell cycle IEA--

    CCNDBP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CCNDBP1 (CCDB1)

    1 HMDB Compound for CCNDBP1    About this table
    CompoundSynonyms CAS #PubMed Ids
    SodiumSodium (see all 2)7440-23-5--

    Search CenterWatch for drugs/clinical trials and news about CCNDBP1 / CCDB1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CCNDBP1 gene (2 alternative transcripts): 
    NM_012142.4  NM_037370.2  

    Unigene Cluster for CCNDBP1:

    Cyclin D-type binding-protein 1
    Hs.36794  [show with all ESTs]
    Unigene Representative Sequence: NM_012142
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000564630(uc021sjs.1) ENST00000300213(uc001zqv.3 uc010udl.2 uc021sjt.1 uc010bdb.3)
    ENST00000566515 ENST00000569745 ENST00000563065 ENST00000567434 ENST00000566833
    ENST00000568507 ENST00000565296(uc021sju.1) ENST00000562553 ENST00000567690
    ENST00000444658(uc001zqy.3) ENST00000566882 ENST00000568936 ENST00000565958
    ENST00000356633
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    hsa-miR-136 hsa-miR-1179 hsa-miR-3921 hsa-miR-340 hsa-miR-3144-3p hsa-miR-3922-3p hsa-miR-4287 hsa-miR-9
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCNDBP1
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    Additional mRNA sequence: 

    AF082569.1 AF087852.1 AF132034.1 AF246144.1 AK225143.1 AK225645.1 AK290665.1 AK290707.1 
    AK295017.1 BC009689.1 CR450331.1 NR_027513.2 NR_027514.2 NR_045998.1 NR_045999.1 

    24/25 DOTS entries (see all 25):

    DT.92443948  DT.100828950  DT.100828948  DT.100829729  DT.100751104  DT.95147136  DT.100828952  DT.100801128 
    DT.100654188  DT.100828946  DT.116592  DT.121051238  DT.101976190  DT.429308  DT.101983802  DT.95147142 
    DT.100828940  DT.100828949  DT.100761380  DT.100828938  DT.100828945  DT.91823930  DT.92443947  DT.95147148 

    24/344 AceView cDNA sequences (see all 344):

    AW090249 BI793217 AA373117 BQ022248 BU526764 AI805606 CA307190 AI050888 
    AA862628 CR605918 AA639542 BM928257 H53894 AI745037 CR623865 CB161702 
    BX365544 BG469516 CK299940 AA749283 CR607951 BU743229 BQ184673 CB243856 

    GeneLoc Exon Structure

    5/15 Alternative Splicing Database (ASD) splice patterns (SP) for CCNDBP1 (see all 15)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d · 8e · 8f ^ 9a · 9b ^
    SP1:                          -           -     -           -                 -                                                                             -   
    SP2:                          -           -     -           -                 -                                                                             -   
    SP3:                                                        -                 -                                                                             -   
    SP4:                          -           -     -     -     -                 -                                                                                 
    SP5:                          -           -     -           -                 -     -     -                                                                     

    ExUns: 10a · 10b ^ 11
    SP1:  -               
    SP2:                  
    SP3:  -               
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for CCNDBP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CCNDBP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTTCTCATT
    CCNDBP1 Expression
    About this image


    See CCNDBP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CCNDBP1

    SOURCE GeneReport for Unigene cluster: Hs.36794

    UniProtKB/Swiss-Prot: CCDB1_HUMAN, O95273
    Tissue specificity: Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including
    breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCNDBP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CCNDBP1 gene from 5/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccndbp11 , 5 cyclin D-type binding-protein 11, 5 84.08(n)1
    82.3(a)1
      2 (60.37 cM)5
    171511  NM_010761.21  NP_034891.21 
     1210084035 
    chicken
    (Gallus gallus)
    Aves CCNDBP11 cyclin D-type binding-protein 1 61.37(n)
    53.21(a)
      419217  XM_417394.3  XP_417394.1 
    lizard
    (Anolis carolinensis)
    Reptilia CCNDBP16
    cyclin D-type binding-protein 1
    41(a)
    1 ↔ 1
    GL343820.1(35886-46041)
    African clawed frog
    (Xenopus laevis)
    Amphibia BX853508.12   -- 76.06(n)    BX853508.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1620821 zgc:162082 54.47(n)
    42.68(a)
      553373  NM_001089365.1  NP_001082834.1 


    ENSEMBL Gene Tree for CCNDBP1 (if available)
    TreeFam Gene Tree for CCNDBP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/266 SNPs in CCNDBP1 are shown (see all 266)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1833381081,2
    --43477938(+) GCCGGA/GCTTGG 5 -- int10--------
    rs2021033441,2
    C--43478036(+) GGAGAC/G/TCACCG 10 T S I mis1 int10--------
    rs3696289391,2
    C--43478095(+) CCTTCC/TGGGCT 5 -- int10--------
    rs1419439081,2
    C--43478109(+) CTTGCC/TTCAGT 5 -- int10--------
    rs5405871,2
    C,F,A,H--43478113(+) CCTCAC/GTTCCT 5 -- int121Minor allele frequency- G:0.25NS EA NA MN WA CSA 2520
    rs2009728431,2
    C--43478119(+) TTCCTC/TCAGCG 5 -- int10--------
    rs1888459491,2
    --43478151(+) CTGTCC/TCCCAC 5 -- int10--------
    rs10782431,2
    C--43478156(-) CCTCCC/GTGGGG 5 -- int14Minor allele frequency- G:0.49NA MN CSA WA 306
    rs797521411,2
    C,F--43478170(+) CTGCTC/TTCCCC 5 -- int13Minor allele frequency- T:0.08CSA WA 122
    rs1458964621,2
    C--43478207(+) TACCCA/GCCTCA 5 -- int10--------

    HapMap Linkage Disequilibrium report for CCNDBP1 (43477316 - 43488229 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for CCNDBP1:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv2368n71CNV Loss21882294
    nsv525461CNV Loss19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607089    OMIM disorders: --

    10 diseases for CCNDBP1:    About MalaCards
    optic disk drusen    congenital dyserythropoietic anemia type i    congenital dyserythropoietic anemia    ischemic optic neuropathy
    anemia    neuropathy    colon cancer    hepatitis
    breast cancer    prostatitis

    1 disease from the University of Copenhagen DISEASES database for CCNDBP1:
    Optic disk drusen

    CCNDBP1 for disorders           About GeneDecksing


    Export disorders for CCNDBP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CCNDBP1 gene, integrated from 9 sources (see all 32):
    (articles sorted by number of sources associating them with CCNDBP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. GCIP, a novel human grap2 and cyclin D interacting protein, regulates E2F-mediated transcriptional activity. (PubMed id 10801854)1, 2, 3, 9 Xia C....Liu M. (2000)
    2. GCIP/CCNDBP1, a helix-loop-helix protein, suppresses tumorigenesis. (PubMed id 17131381)1, 2, 9 Ma W....Liu M. (2007)
    3. Ribosomal phosphoprotein P0 interacts with GCIP and overexpression of P0 is associated with cellular proliferation in breast and liver carcinoma cells. (PubMed id 17621266)1, 2, 9 Chang T.-W....Chang M.-C. (2008)
    4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    5. Human homologue of maid is a useful marker protein in hepatocarcinogenesis. (PubMed id 15887118)1, 2 Takami T.... Okita K. (2005)
    6. Human homologue of maid: a dominant inhibitory helix-loop-helix protein associated with liver-specific gene expression. (PubMed id 10915743)1, 2 Terai S.... Thorgeirsson S.S. (2000)
    7. Cloning and characterization of DIP1, a novel protein that is related to the Id family of proteins. (PubMed id 10854051)1, 2 Yao Y.... Weinstein I.B. (2000)
    8. p29, a novel GCIP-interacting protein, localizes in the nucleus. (PubMed id 11118353)1, 2 Chang M.-S.... Yang Y.-C. (2000)
    9. Human GCIP interacts with CT847, a novel Chlamydia trachomatis type III secretion substrate, and is degraded in a tissue-culture infection model. (PubMed id 17532760)1, 9 Chellas-Gery B....Fields K.A. (2007)
    10. Structure of a dominant-negative helix-loop-helix tran scriptional regulator suggests mechanisms of autoinhibition. (PubMed id 22453338)1 Ishii R....Nureki O. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23582 HGNC: 1587 AceView: CCNDBP1 Ensembl:ENSG00000166946 euGenes: HUgn23582
    ECgene: CCNDBP1 H-InvDB: CCNDBP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CCNDBP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CCNDBP1 gene:
    Search GeneIP for patents involving CCNDBP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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