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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CCNB1IP1 Gene

protein-coding   GIFtS: 54
GCID: GC14M020779

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

(Previous names: chromosome 14 open reading frame 18, cyclin B1 interacting...)
(Previous symbol: C14orf18)
 Explore 3 diseases affiliated with
CCNB1IP1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CCNB1IP1    

Aliases
for CCNB1IP1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Cyclin B1 Interacting Protein 1, E3 Ubiquitin Protein Ligase1 2     Cyclin B1 Interacting Protein 11
C14orf181 2 3 5     E3 Ubiquitin-Protein Ligase CCNB1IP12
HEI101 2 3 5     EC 6.3.2.-3
Human Enhancer Of Invasion 102 3     Cyclin-B1-Interacting Protein 13
Chromosome 14 Open Reading Frame 181     

External Ids:    HGNC: 194371   Entrez Gene: 578202   Ensembl: ENSG000001008147   OMIM: 6082495   UniProtKB: Q9NPC33   

Export aliases for CCNB1IP1 gene to outside databases

Previous GC identifers: GC14M018770 GC14M018771 GC14M019849 GC14M000901


Summaries
for CCNB1IP1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CCNB1IP1:
HEI10 is a member of the E3 ubiquitin ligase family and functions in progression of the cell cycle through
G(2)/M.(supplied by OMIM, Apr 2004)

UniProtKB/Swiss-Prot: CIP1_HUMAN, Q9NPC3
Function: E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle
progression through the G2 phase. Overexpression causes delayed entry into mitosis

Gene Wiki entry for CCNB1IP1


Genomic Views
for CCNB1IP1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CCNB1IP1 gene promoter:
         N-Myc   GCNF-1   GCNF   STAT5A   GCNF-2   Evi-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CCNB1IP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CCNB1IP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCNB1IP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q11.2   Ensembl cytogenetic band:  14q11.2   HGNC cytogenetic band: 14q11.2

CCNB1IP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCNB1IP1 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M020779:  view genomic region     (about GC identifiers)

Start:
 20,779,527 bp from pter      End:
 20,801,471 bp from pter
Size:
 21,945 bases      Orientation:
 minus strand

Proteins
for CCNB1IP1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CIP1_HUMAN, Q9NPC3 (See protein sequence)
Recommended Name: E3 ubiquitin-protein ligase CCNB1IP1  
Size: 277 amino acids; 31544 Da
Subunit: Binds CCNB1 and UBE2L3
Subcellular location: Nucleus. Chromosome. Note=May associate with segregating chromosomes during metaphase and
anaphase

Explore the universe of human proteins at neXtProt for CCNB1IP1: NX_Q9NPC3

Post-translational modifications:

  • Ubiquitinated; autoubiquitinated1
  • Phosphorylated by CDK1 on serine or threonine residues (in vitro)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NPC3

    • CCNB1IP1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_067001.3  NP_878269.1  NP_878272.1  

    ENSEMBL proteins: 
     ENSP00000381226   ENSP00000381235   ENSP00000351810   ENSP00000381229   ENSP00000451122  
     ENSP00000452463   ENSP00000452486   ENSP00000450914   ENSP00000452312   ENSP00000452182  
     ENSP00000337396   ENSP00000409896  

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    Novus Biologicals CCNB1IP1 Proteins
    Novus Biologicals CCNB1IP1 Lysates
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CCNB1IP1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005694chromosome IEA--


    CCNB1IP1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for CCNB1IP1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q9NPC3

    1 Blocks protein family: IPB001841 Zn-finger

    UniProtKB/Swiss-Prot: CIP1_HUMAN, Q9NPC3
    Similarity: Contains 1 RING-type zinc finger


    Function
    for CCNB1IP1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CIP1_HUMAN, Q9NPC3
    Function: E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle
    progression through the G2 phase. Overexpression causes delayed entry into mitosis

    Enzyme Number (IUBMB): EC 6.3.2.-1

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    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12612082
    GO:0016874ligase activity IEA--
    GO:0046872metal ion binding IEA--


    CCNB1IP1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for CCNB1IP1:
     Synthetic lethal with c-Myc af 

    Animal Models:
         2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Ccnb1ip1):
     endocrine/exocrine gland  reproductive system 

    CCNB1IP1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for CCNB1IP1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Integrated Breast Cancer Pathway
    		Integrated Breast Cancer Pathway1.00


    1 BioSystems Pathway for CCNB1IP1 
        Integrated Breast Cancer Pathway


    UniProtKB/Swiss-Prot: CIP1_HUMAN, Q9NPC3
    Pathway: Protein modification; protein ubiquitination

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CCNB1IP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/33 Interacting proteins for CCNB1IP1 (Q9NPC31, 2, 3 ENSP000003373964) via UniProtKB, MINT, STRING, and/or I2D (see all 33)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCNB1P146351, 3, ENSP000002564424EBI-745269,EBI-495332 I2D: score=2 STRING: ENSP00000256442
    UBE2L3P680363, ENSP000003442594I2D: score=2 STRING: ENSP00000344259
    CCNB1IP1Q9NPC32MINT-66642
    PHF12ENSP000003299334STRING: ENSP00000329933
    POMPENSP000003702224STRING: ENSP00000370222
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001825blastocyst formation IEA--
    GO:0006915apoptotic process IEA--
    GO:0007132meiotic metaphase I IEA--
    GO:0007286spermatid development IEA--
    GO:0016567protein ubiquitination IEA--


    CCNB1IP1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CCNB1IP1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for CCNB1IP1

    4 HMDB Compounds for CCNB1IP1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine monophosphate5'-AMP (see all 28)61-19-8--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Phosphoric acidacide phosphorique (FRENCH) (see all 20)7664-38-2--
    Pyrophosphate(4-)Diphosphoric acid ion (see all 10)14000-31-8--
    Search CenterWatch for drugs/clinical trials and news about CCNB1IP1 / CIP1 

    Transcripts
    for CCNB1IP1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CCNB1IP1 gene (4 alternative transcripts): 
    NM_182851.1  NM_021178.4  NM_182849.2  NM_182852.3  

    Unigene Cluster for CCNB1IP1:

    Cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
    Hs.107003  [show with all ESTs]
    Unigene Representative Sequence: NM_182852
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000398160(uc001vwx.3) ENST00000556204 ENST00000398169 ENST00000358932(uc001vwz.3)
    ENST00000398163(uc001vwv.3) ENST00000554184 ENST00000556854(uc010ahh.1)
    ENST00000557665 ENST00000554047 ENST00000556563 ENST00000553291 ENST00000553516
    ENST00000555348 ENST00000557114 ENST00000555963 ENST00000353689(uc001vwy.3)
    ENST00000437553(uc021rnp.1)

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    Inhib. RNA
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    OriGene shRNA RFP: CCNB1IP1
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    Clone
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    Additional cDNA sequence: 

    AF216381.1 AK026233.1 AK225253.1 AK225451.1 AK226037.1 AL161994.1 BC000369.2 BC001218.1 
    BC004435.1 

    17 DOTS entries:

    DT.115981  DT.95211208  DT.100643350  DT.101986400  DT.101986399  DT.100879858  DT.100879857  DT.100879862 
    DT.91764188  DT.99946032  DT.100879867  DT.100879871  DT.86841881  DT.95104464  DT.97848327  DT.100659926 
    DT.100683438 

    24/373 AceView cDNA sequences (see all 373):

    CA418125 AI032812 NM_182851 AA406358 F10039 BQ053161 BQ642590 AW247345 
    AA873540 BU171076 AI367071 BQ223690 BM263179 BQ576273 AW007782 BQ575335 
    BM971724 CF541065 BM741413 CR593880 AA205107 AF216381 BX346767 NM_182852 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for CCNB1IP1 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b
    SP1:              -                                   -                                                         
    SP2:                                                  -                       -     -                           
    SP3:                                                  -                       -                                 
    SP4:                                                                                -                           
    SP5:                                                                                                            


    ECgene alternative splicing isoforms for CCNB1IP1

    Expression
    for CCNB1IP1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CCNB1IP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATTGCACAGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CCNB1IP1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Yolk SacDefinitive Yolk SacDefinitive Hematopoietic Stem CellsBlood
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See CCNB1IP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CCNB1IP1

    SOURCE GeneReport for Unigene cluster: Hs.107003

    UniProtKB/Swiss-Prot: CIP1_HUMAN, Q9NPC3
    Tissue specificity: Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels
    in placenta, brain and lung

        SABiosciences Expression via Pathway-Focused PCR Array including CCNB1IP1: 
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    In Situ
    Assay Products:     
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    Orthologs
    for CCNB1IP1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CCNB1IP1 gene from 5/17 species (see all 17)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Ccnb1ip11 , 5 cyclin B1 interacting protein 11, 5 87.2(n)1
    88.77(a)1    		   14 (26.25 cM)5
    2390831  NM_001111119.11  NP_001104589.11 
     507892495 
    lizard
    (Anolis carolinensis)    		 Reptilia CCNB1IP16
    		 --
    		 76(a)
    		 1 ↔ 1
    		 GL343220.1(1038704-1041432)
    zebrafish
    (Danio rerio)    		 Actinopterygii LOC5628251 e3 ubiquitin-protein ligase CCNB1IP1-like 58.26(n)
    56.2(a)    		   562825  XM_686198.4  XP_691290.3 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT1G534906
    		 RING/U-box domain-containing protein
    		 17(a)
    		 1 ↔ 1
    		 1(19963267-19966952)
    rice
    (Oryza sativa)    		 Liliopsida --
    		 DNA binding protein, putative, expressed
    		 18(a)
    		 1 ↔ 1
    		 2(7466238-7470926)


    ENSEMBL Gene Tree for CCNB1IP1 (if available)
    TreeFam Gene Tree for CCNB1IP1 (if available) 

    Paralogs
    for CCNB1IP1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CCNB1IP1 gene

    CCNB1IP1 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for CCNB1IP1
    PGOHUM00000244697 PGOHUM00000247547 PGOHUM00000241452


    Genomic Variants
    for CCNB1IP1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/426 NCBI SNPs in CCNB1IP1 are shown (see all 426)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 14 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs795621671,2
    		C,--904732(+) CAGGT-/GGATCT 1 -- int10--------
    rs1429188421,2
    		--20779141(+) CCAACC/TCTGTG 3 -- ds50010--------
    rs1511026451,2
    		C,--20779172(+) GTCCAC/TTCAGG 3 -- ds50010--------
    rs125882131,2
    		C,H,--20779176(+) ACTCAC/GGGTTA 3 -- ds50010--------
    rs2010946161,2
    		--20779287(+) GGACA-/CAAACA 3 -- ds50010--------
    rs124315721,2
    		H--20779436(+) aaaaaA/Taataa 3 -- ds50010--------
    rs1855669311,2
    		--20779497(+) AAATGA/TAATCA 3 -- ds50010--------
    rs748300241,2
    		C,F,--20779540(+) TAGCTA/GAATTA 3 -- ut311Minor allele frequency- G:0.05WA 118
    rs1903524661,2
    		--20779603(+) CAGTGA/GCATGA 3 -- ut310--------
    rs1817147951,2
    		C,--20779691(+) AGGTGC/TGTGAC 3 -- ut310--------

    HapMap Linkage Disequilibrium report for CCNB1IP1 (20779527 - 20801471 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for CCNB1IP1
         1 CNV: 71865
         1 Indel: 101891

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    Disorders / Diseases
    for CCNB1IP1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CCNB1IP1 for disorders           About GeneDecksing

    OMIM gene information: 608249    OMIM disorders: --

    3 diseases for CCNB1IP1:    About MalaCards
    smooth muscle tumor    intrahepatic cholangiocarcinoma    cholangiocarcinoma


    Export disorders for CCNB1IP1 gene to outside databases

    Publications
    for CCNB1IP1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CCNB1IP1 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with CCNB1IP1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel RING finger protein, human enhancer of invasion 10, alters mitotic progression through regulation of cyclin B levels. (PubMed id 12612082)1, 2, 3, 9 Toby G.G.... Golemis E.A. (2003)
    2. Evidence Implicating CCNB1IP1, a RING Domain-Containi ng Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase. (PubMed id 21779533)1, 3 Strong E.R. and Schimenti J.C. (2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    6. Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)1 Emanuele M.J....Elledge S.J. (2011)
    7. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. A functional association between merlin and HEI10, a cell cycle regulator. (PubMed id 16532029)1 Gronholm M....Carpen O. (2006)

    External Searches for CCNB1IP1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing CCNB1IP1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57820 HGNC: 19437 AceView: CCNB1IP1 Ensembl:ENSG00000100814 euGenes: HUgn57820
    ECgene: CCNB1IP1 H-InvDB: CCNB1IP1

    Other Databases showing CCNB1IP1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CCNB1IP1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CCNB1IP1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CCNB1IP1 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for CCNB1IP1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CCNB1IP1 gene:
    Search GeneIP for patents involving CCNB1IP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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