Aliases for CCNB1 Gene
External Ids for CCNB1 Gene
Previous HGNC Symbols for CCNB1 Gene
Previous GeneCards Identifiers for CCNB1 Gene
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). The encoded protein is necessary for proper control of the G2/M transition phase of the cell cycle. [provided by RefSeq, Aug 2017]
GeneCards Summary for CCNB1 Gene
CCNB1 (Cyclin B1) is a Protein Coding gene. Diseases associated with CCNB1 include Thyroid Lymphoma and Adrenal Carcinoma. Among its related pathways are Arrhythmogenic right ventricular cardiomyopathy (ARVC) and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include protein kinase binding and patched binding. An important paralog of this gene is CCNB2.
UniProtKB/Swiss-Prot for CCNB1 Gene
Essential for the control of the cell cycle at the G2/M (mitosis) transition.