Aliases for CCNB1 Gene
External Ids for CCNB1 Gene
Previous HGNC Symbols for CCNB1 Gene
Previous GeneCards Identifiers for CCNB1 Gene
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008]
GeneCards Summary for CCNB1 Gene
CCNB1 (Cyclin B1) is a Protein Coding gene. Diseases associated with CCNB1 include Adrenal Carcinoma and Thyroid Lymphoma. Among its related pathways are DNA Damage Induced 14-3-3Sigma Signaling and Regulation of PLK1 Activity at G2/M Transition. GO annotations related to this gene include protein kinase binding and patched binding. An important paralog of this gene is CCNB2.
UniProtKB/Swiss-Prot for CCNB1 Gene
Essential for the control of the cell cycle at the G2/M (mitosis) transition.