External Ids for CCNA2 Gene
Previous HGNC Symbols for CCNA2 Gene
Previous GeneCards Identifiers for CCNA2 Gene
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members function as regulators of the cell cycle. This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M. [provided by RefSeq, Aug 2016]
GeneCards Summary for CCNA2 Gene
CCNA2 (Cyclin A2) is a Protein Coding gene. Diseases associated with CCNA2 include Lung Clear Cell Carcinoma and Valproate Embryopathy, Susceptibility To. Among its related pathways are Regulation of retinoblastoma protein and Regulation of activated PAK-2p34 by proteasome mediated degradation. GO annotations related to this gene include protein kinase binding. An important paralog of this gene is CCNA1.
UniProtKB/Swiss-Prot for CCNA2 Gene
Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.