Aliases for CCNA1 Gene
External Ids for CCNA1 Gene
- HGNC: 1577
- Entrez Gene: 8900
- Ensembl: ENSG00000133101
- OMIM: 604036
- UniProtKB: P78396
Previous GeneCards Identifiers for CCNA1 Gene
- GC13P034993
- GC13P030993
- GC13P035942
- GC13P034804
- GC13P035904
- GC13P037005
- GC13P017817
Summaries for CCNA1 Gene
-
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for CCNA1 Gene
CCNA1 (Cyclin A1) is a Protein Coding gene. Diseases associated with CCNA1 include Myeloid Leukemia and Leukemia, Acute Promyelocytic, Somatic. Among its related pathways are DNA Double-Strand Break Repair and Regulation of TP53 Activity. GO annotations related to this gene include protein kinase binding. An important paralog of this gene is CCNA2.
UniProtKB/Swiss-Prot for CCNA1 Gene
-
May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCNA1 Gene
Genomics for CCNA1 Gene
Regulatory Elements for CCNA1 Gene
Enhancers for CCNA1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH13G036772 | 0.4 | ENCODE | 10.4 | +342.0 | 342044 | 0.8 | ATF2 | CCNA1 LOC102723490 TCEAL4P1 |
| GH13G036717 | 0.4 | ENCODE | 9.7 | +287.0 | 287046 | 0.7 | FOS | SERTM1 CCNA1 RFXAP GAPDHP34 |
| GH13G036373 | 0.6 | dbSUPER | 4.5 | -56.3 | -56307 | 1.6 | FOXA1 YY1 JUND SMARCA4 ATF3 FOS ZBTB33 HNF4A | CCDC169 SPG20-AS1 CCNA1 SPG20 |
| GH13G036074 | 0.6 | FANTOM5 ENCODE | 4 | -356.1 | -356089 | 0.7 | EP300 | CCNA1 DCLK1 CCDC169 NMTRQ-TTG10-1 |
| GH13G036279 | 0.3 | FANTOM5 | 2.9 | -151.9 | -151920 | 0.0 | RFXAP CCDC169 CCNA1 RNU6-71P CCDC169-SOHLH2 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CCNA1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CCNA1 gene promoter:
Regulatory Element Products
Genomic Location for CCNA1 Gene
- Chromosome:
- 13
- Start:
- 36,431,030 bp from pter
- End:
- 36,442,882 bp from pter
- Size:
- 11,853 bases
- Orientation:
- Plus strand
Genomic View for CCNA1 Gene
Genes around CCNA1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q13.3 by Ensembl
- 13q13.3 by Entrez Gene
- 13q13.3 by HGNC
CCNA1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CCNA1 Gene
Proteins for CCNA1 Gene
-
Protein details for CCNA1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P78396-CCNA1_HUMAN
- Recommended name:
- Cyclin-A1
- Protein Accession:
- P78396
- B7Z7E3
- Q5T3V0
- Q5U0G2
- Q8IY91
Protein attributes for CCNA1 Gene
- Size:
- 465 amino acids
- Molecular mass:
- 52358 Da
- Quaternary structure:
-
- Interacts with the CDK2 and the CDC2 protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. Does not bind CDK4 and CDK5 (in vitro). The cyclin A1-CDK2 complex interacts with transcription factor E2F-1 and RB proteins. Found in a complex with CDK2, CABLES1 and CCNE1 (By similarity). Interacts with INCA1 and KLHDC9.
Protein Expression for CCNA1 Gene
Post-translational modifications for CCNA1 Gene
- Polyubiquitinated via Lys-11-linked ubiquitin by the anaphase-promoting complex (APC/C), leading to its degradation by the proteasome. Deubiquitinated and stabilized by USP37 enables entry into S phase.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for CCNA1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for CCNA1 (Cyclin A1)
-
Custom Antibody ServicesOriGene Antibodies for CCNA1
- Novus Biologicals Antibodies for CCNA1
-
Cloud-Clone Corp. Antibodies for CCNA1
- Invitrogen Antibodies for CCNA1
- antibodies-online Antibodies for CCNA1: See all 93
- Search GeneTex for Antibodies for CCNA1
-
Santa Cruz Biotechnology (SCBT) Antibodies for CCNA1
Protein Products
-
OriGene Purified Proteins for CCNA1
- Search Origene for MassSpec and Protein Over-expression Lysates for CCNA1
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- Sino Biological Recombinant Proteins for CCNA1
- Sino Biological Cell Lysates for CCNA1
-
Cloud-Clone Corp. Proteins for CCNA1
- antibodies-online Proteins for CCNA1: See all 8
- Search antibodies-online for peptides
- Search GeneTex for Proteins for CCNA1
-
Abcam proteins for CCNA1
No data available for DME Specific Peptides for CCNA1 Gene
Domains & Families for CCNA1 Gene
Gene Families for CCNA1 Gene
- HGNC:
Protein Domains for CCNA1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CCNA1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P78396- Family:
-
- Belongs to the cyclin family. Cyclin AB subfamily.
Function for CCNA1 Gene
Molecular function for CCNA1 Gene
- GENATLAS Biochemistry:
- cyclin A1,complexing with CDK2,expressed in meiotic cell in the testis and brain and in several leukemic cell lines,regulator of cell-cycle
- UniProtKB/Swiss-Prot Function:
- May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 8756624 |
Phenotypes for CCNA1 Gene
- MGI mutant phenotypes for CCNA1:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for CCNA1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCNA1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CCNA1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCNA1 gene
- Search ViGene Biosciences for CCNA1
CRISPR Products
-
OriGene CRISPR knockouts for CCNA1
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCNA1
- GenScript: Design CRISPR guide RNA sequences for CCNA1
miRNA for CCNA1 Gene
- miRTarBase miRNAs that target CCNA1
miRNA Products
- Search ViGene Biosciences for CCNA1
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for CCNA1
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-
ViGene Biosciences ready-to-package AAV shRNAs for CCNA1 gene
Clone Products
- Sino Biological Human cDNA Clone for CCNA1
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- VectorBuilder custom plasmid, inducible vectors for CCNA1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCNA1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CCNA1
-
ViGene Biosciences adenoviral particle packaged cDNA for CCNA1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CCNA1 gene
-
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CCNA1 Gene
Localization for CCNA1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CCNA1 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| nucleus | 5 |
| cytosol | 5 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005829 | cytosol | TAS | 9041194 |
| GO:0015630 | microtubule cytoskeleton | IDA | -- |
| GO:0097123 | cyclin A1-CDK2 complex | IEA | -- |
Pathways & Interactions for CCNA1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | CDK-mediated phosphorylation and removal of Cdc6 |
.93
.93
.78
|
|
| 2 | DNA Double-Strand Break Repair |
.53
|
|
| 3 | Cell cycle Cell cycle (generic schema) |
.31
.01
|
|
| 4 | AMP-activated Protein Kinase (AMPK) Signaling | ||
| 5 | Cellular Senescence | ||
Pathways by source for CCNA1 Gene
1 Sino Biological pathway for CCNA1 Gene
1 GeneTex pathway for CCNA1 Gene
5 BioSystems pathways for CCNA1 Gene
55 Reactome pathways for CCNA1 Gene
- Activation of APC/C and APC/C-Cdc20 mediated degradation of mitotic proteins
- APC/C-Cdc20 mediated degradation of mitotic proteins
- APC/C-mediated degradation of cell cycle proteins
- APC-Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
- Cdc20-Phospho-APC/C mediated degradation of Cyclin A
9 KEGG pathways for CCNA1 Gene
9 GeneGo (Thomson Reuters) pathways for CCNA1 Gene
Interacting Proteins for CCNA1 Gene
Selected Interacting proteins:
ENSP00000255465
P78396-CCNA1_HUMAN
for CCNA1 Gene via
STRING
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle | TAS | -- |
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007067 | mitotic nuclear division | IEA | -- |
| GO:0007141 | male meiosis I | TAS | 9843212 |
| GO:0007283 | spermatogenesis | TAS | 9843212 |
Transcripts for CCNA1 Gene
mRNA/cDNA for CCNA1 Gene
- (7) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (68) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CCNA1
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCNA1
- GenScript: Design CRISPR guide RNA sequences for CCNA1
miRNA Products
- Search ViGene Biosciences for CCNA1
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for CCNA1
- Browse OriGene Inhibitory RNA Products For CCNA1
-
ViGene Biosciences ready-to-package AAV shRNAs for CCNA1 gene
Clone Products
- Sino Biological Human cDNA Clone for CCNA1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CCNA1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCNA1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||
| SP5: | - | - | - | - |
Expression for CCNA1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Inner Cell Mass (Early Embryonic Tissues)
- Endothelium (Cardiovascular System)
- Testis (Reproductive System)
- Bone (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for CCNA1 Gene
This gene is overexpressed in Testis (x15.6) and Whole Blood (x4.3).
This gene is overexpressed in Heart (35.9) and Testis (33.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CCNA1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CCNA1 Gene:
CCNA1SOURCE GeneReport for Unigene cluster for CCNA1 Gene:
Hs.417050mRNA Expression by UniProt/SwissProt for CCNA1 Gene:
P78396-CCNA1_HUMAN
Tissue specificity:
Very high levels in testis and very low levels in brain. Also found in myeloid leukemia cell lines.
Evidence on tissue expression from TISSUES for CCNA1 Gene
- Nervous system(4.4)
- Blood(4.3)
- Lymph node(4)
- Spleen(4)
Primer Products
-
OriGene qPCR primer pairs and template standards for CCNA1
-
OriGene qPCR primer pairs for CCNA1
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for CCNA1 Gene
Orthologs for CCNA1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CCNA1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | CCNA1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CCNA1 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ccna1 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Ccna1 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CCNA1 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CCNA1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CCNA1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CCNA1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ccna1 34 |
|
||
| Str.4034 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | LOC397885 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ccna1 34 35 |
|
||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.2245 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CycA 36 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | ZK507.6 36 |
|
|
|
| thale cress (Arabidopsis thaliana) |
eudicotyledons | CYCA3;2 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os03g0607600 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.10122 35 |
|
OneToMany | |
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.5837 34 |
|
- Species where no ortholog for CCNA1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for CCNA1 Gene
Variants for CCNA1 Gene
| SNP ID | Clin | Chr 13 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000039439 | -- | 36,436,998(+) | CACAG(A/T)TGTTC | intron-variant | |
| rs1000557771 | -- | 36,436,774(+) | TGGAA(C/T)CACCT | intron-variant | |
| rs1000618259 | -- | 36,433,309(+) | GTACC(C/T)ACAAC | intron-variant | |
| rs1000820410 | -- | 36,431,378(+) | AGGAG(C/T)CCCCC | upstream-variant-2KB, utr-variant-5-prime | |
| rs1000968174 | -- | 36,437,265(+) | ATAAA(A/G)TCTCA | intron-variant |
Residual Variation Intolerance Score:
23.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.16;
23.38% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CCNA1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CCNA1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCNA1 Gene
Disorders for CCNA1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| myeloid leukemia |
|
|
| leukemia, acute promyelocytic, somatic |
|
|
| leukemia, acute myeloid |
|
|
Search CCNA1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for CCNA1
No data available for UniProtKB/Swiss-Prot and Genatlas for CCNA1 Gene
Publications for CCNA1 Gene
- Characterization of a second human cyclin A that is highly expressed in testis and in several leukemic cell lines. (PMID: 9041194) Yang R. … Koeffler H.P. (Cancer Res. 1997) 2 3 4 22 64
- Mutations of the cyclin A1 gene are not a common cause of male infertility. (PMID: 19886767) Zhoucun A. … Yang Y. (Syst Biol Reprod Med 2009) 3 22 46 64
- Functions of cyclin A1 in the cell cycle and its interactions with transcription factor E2F-1 and the Rb family of proteins. (PMID: 10022926) Yang R. … Koeffler H.P. (Mol. Cell. Biol. 1999) 3 4 22 64
- KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation. (PMID: 20457893) Hsia D.A. … Izumiya Y. (Proc. Natl. Acad. Sci. U.S.A. 2010) 3 22 64
- Post-translational modification of cyclin A1 is associated with staurosporine and TNFalpha induced apoptosis in leukemic cells. (PMID: 18787932) Ekberg J. … Persson J.L. (Mol. Cell. Biochem. 2009) 3 22 64
Products for CCNA1 Gene
- R&D Systems Antibodies for CCNA1 (Cyclin A1)
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- OriGene qPCR primer pairs and template standards for CCNA1
- OriGene qPCR primer pairs for CCNA1
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- Novus Biologicals
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- Find your target
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- Cloud-Clone Corp. Antibodies for CCNA1
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- Invitrogen Antibodies for CCNA1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for CCNA1: See all 93
- antibodies-online Kits for CCNA1: See all 6
- antibodies-online Proteins for CCNA1: See all 8
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for CCNA1
- Search GeneTex for Proteins for CCNA1
- ViGene Biosciences adenoviral particle packaged cDNA for CCNA1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CCNA1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CCNA1 gene
- Search ViGene Biosciences for CCNA1
- Santa Cruz Biotechnology (SCBT) Antibodies for CCNA1
- Search Santa Cruz Biotechnology (SCBT) for CCNA1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CCNA1
- Horizon Cell Lines for CCNA1
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCNA1
- VectorBuilder custom plasmid, inducible vectors for CCNA1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCNA1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CCNA1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
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