Aliases for CCNA1 Gene
External Ids for CCNA1 Gene
- HGNC: 1577
- Entrez Gene: 8900
- Ensembl: ENSG00000133101
- OMIM: 604036
- UniProtKB: P78396
Previous GeneCards Identifiers for CCNA1 Gene
- GC13P034993
- GC13P030993
- GC13P035942
- GC13P034804
- GC13P035904
- GC13P037005
- GC13P017817
Summaries for CCNA1 Gene
-
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for CCNA1 Gene
CCNA1 (Cyclin A1) is a Protein Coding gene. Diseases associated with CCNA1 include Myeloid Leukemia and Leukemia, Acute Promyelocytic, Somatic. Among its related pathways are Packaging Of Telomere Ends and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include protein kinase binding. An important paralog of this gene is CCND2.
UniProtKB/Swiss-Prot for CCNA1 Gene
-
May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCNA1 Gene
Genomics for CCNA1 Gene
Regulatory Elements for CCNA1 Gene
Enhancers for CCNA1 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around CCNA1 on UCSC Golden Path with GeneCards custom track
Promoters for CCNA1 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around CCNA1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CCNA1 gene promoter:
Regulatory Element Products
Genomic Location for CCNA1 Gene
- Chromosome:
- 13
- Start:
- 36,431,030 bp from pter
- End:
- 36,442,882 bp from pter
- Size:
- 11,853 bases
- Orientation:
- Plus strand
Genomic View for CCNA1 Gene
Genes around CCNA1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 13q13.3 by Ensembl
- 13q12.3-q13 by Entrez Gene
- 13q12.3-q13 by HGNC
CCNA1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CCNA1 Gene
Proteins for CCNA1 Gene
-
Protein details for CCNA1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P78396-CCNA1_HUMAN
- Recommended name:
- Cyclin-A1
- Protein Accession:
- P78396
- B7Z7E3
- Q5T3V0
- Q5U0G2
- Q8IY91
Protein attributes for CCNA1 Gene
- Size:
- 465 amino acids
- Molecular mass:
- 52358 Da
- Quaternary structure:
-
- Interacts with the CDK2 and the CDC2 protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. Does not bind CDK4 and CDK5 (in vitro). The cyclin A1-CDK2 complex interacts with transcription factor E2F-1 and RB proteins. Found in a complex with CDK2, CABLES1 and CCNE1 (By similarity). Interacts with INCA1 and KLHDC9.
Protein Expression for CCNA1 Gene
Post-translational modifications for CCNA1 Gene
- Polyubiquitinated via Lys-11-linked ubiquitin by the anaphase-promoting complex (APC/C), leading to its degradation by the proteasome. Deubiquitinated and stabilized by USP37 enables entry into S phase.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for CCNA1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for CCNA1
- R&D Systems Antibodies for CCNA1 (Cyclin A1)
- Novus Biologicals Antibodies for CCNA1
-
Cloud-Clone Corp. Antibodies for CCNA1
- Invitrogen Antibodies for CCNA1
- antibodies-online Antibodies for CCNA1: See all 93
- Search GeneTex for Antibodies for CCNA1
-
Santa Cruz Biotechnology (SCBT) Antibodies for CCNA1
Protein Products
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- Sino Biological Recombinant Proteins for CCNA1
-
Cloud-Clone Corp. Proteins for CCNA1
- antibodies-online Proteins for CCNA1: See all 8
- Search antibodies-online for peptides
- Search GeneTex for Proteins for CCNA1
- Abcam proteins for CDK1 + Cyclin-A1
No data available for DME Specific Peptides for CCNA1 Gene
Domains & Families for CCNA1 Gene
Gene Families for CCNA1 Gene
- HGNC:
Protein Domains for CCNA1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CCNA1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P78396- Family:
-
- Belongs to the cyclin family. Cyclin AB subfamily.
Function for CCNA1 Gene
Molecular function for CCNA1 Gene
- GENATLAS Biochemistry:
- cyclin A1,complexing with CDK2,expressed in meiotic cell in the testis and brain and in several leukemic cell lines,regulator of cell-cycle
- UniProtKB/Swiss-Prot Function:
- May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
Phenotypes for CCNA1 Gene
- MGI mutant phenotypes for CCNA1:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for CCNA1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for CCNA1 gene
-
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- Search ViGene Biosciences for CCNA1
CRISPR Products
-
OriGene CRISPR knockouts for CCNA1
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCNA1
- GenScript: Design CRISPR guide RNA sequences for CCNA1
miRNA for CCNA1 Gene
- miRTarBase miRNAs that target CCNA1
miRNA Products
- Search ViGene Biosciences for CCNA1
Clone Products
- OriGene clones in human for CCNA1
- OriGene ORF clones in human,mouse,rat for CCNA1
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Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for CCNA1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CCNA1 gene
-
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Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CCNA1 Gene
Localization for CCNA1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CCNA1 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| cytosol | 5 |
| nucleus | 5 |
| mitochondrion | 1 |
No data available for Gene Ontology (GO) - Cellular Components for CCNA1 Gene
Pathways & Interactions for CCNA1 Gene
More details on SuperPathways for CCNA1| Superpath | Contained pathways | ||
|---|---|---|---|
| 1 | CDK-mediated phosphorylation and removal of Cdc6 |
.92
.92
|
.78
|
| 2 | DNA Double-Strand Break Repair |
.53
|
|
| 3 | Cell cycle Cell cycle (generic schema) |
.31
1
|
|
| 4 | Cellular Senescence | ||
| 5 | Mitotic G1-G1/S phases |
.82
|
Pathways by source for CCNA1 Gene
1 GeneTex pathway for CCNA1 Gene
5 BioSystems pathways for CCNA1 Gene
51 Reactome pathways for CCNA1 Gene
- Activation of APC/C and APC/C-Cdc20 mediated degradation of mitotic proteins
- APC/C-Cdc20 mediated degradation of mitotic proteins
- APC/C-mediated degradation of cell cycle proteins
- APC-Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
- Cdc20-Phospho-APC/C mediated degradation of Cyclin A
9 KEGG pathways for CCNA1 Gene
9 GeneGo (Thomson Reuters) pathways for CCNA1 Gene
Interacting Proteins for CCNA1 Gene
Selected Interacting proteins:
P78396-CCNA1_HUMAN
ENSP00000255465
for CCNA1 Gene via
MINT
STRING
UniProtKB
I2D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | -- |
| GO:0000278 | mitotic cell cycle | TAS | -- |
| GO:0007141 | male meiosis I | TAS | 9843212 |
| GO:0007283 | spermatogenesis | TAS | 9843212 |
| GO:0051301 | cell division | IEA | -- |
Transcripts for CCNA1 Gene
mRNA/cDNA for CCNA1 Gene
- (8) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (68) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CCNA1
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCNA1
- GenScript: Design CRISPR guide RNA sequences for CCNA1
miRNA Products
- Search ViGene Biosciences for CCNA1
Clone Products
- OriGene clones in human for CCNA1
- OriGene ORF clones in human,mouse,rat for CCNA1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for CCNA1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||
| SP5: | - | - | - | - |
Expression for CCNA1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Inner Cell Mass (Early Embryonic Tissues)
- Endothelium (Cardiovascular System)
- Testis (Reproductive System)
- Bone (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for CCNA1 Gene
This gene is overexpressed in Testis (x15.6) and Whole Blood (x4.3).
This gene is overexpressed in Heart (35.9) and Testis (33.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CCNA1 Gene
SOURCE GeneReport for Unigene cluster for CCNA1 Gene Hs.417050
mRNA Expression by UniProt/SwissProt for CCNA1 Gene
P78396-CCNA1_HUMAN
Tissue specificity:
Very high levels in testis and very low levels in brain. Also found in myeloid leukemia cell lines.
- Elite partner
Primer Products
-
OriGene qPCR primer pairs and template standards for CCNA1
-
OriGene qPCR primer pairs for CCNA1
Orthologs for CCNA1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | CCNA1 35 |
|
||
| CCNA1 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | CCNA1 35 |
|
||
| CCNA1 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Ccna1 35 |
|
||
| Ccna1 16 |
|
||||
| Ccna1 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | CCNA1 35 |
|
||
| CCNA1 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Ccna1 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CCNA1 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CCNA1 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CCNA1 35 |
|
||
| CCNA1 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | CCNA1 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ccna1 35 |
|
||
| Str.4034 35 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | LOC397885 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ccna1 35 |
|
||
| ccna1 36 |
|
OneToOne | |||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.2245 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CycA 37 |
|
|
|
| CycA 36 |
|
OneToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | ZK507.6 37 |
|
|
|
| thale cress (Arabidopsis thaliana) |
eudicotyledons | CYCA3;2 35 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os03g0607600 35 |
|
||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.5837 35 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.10122 36 |
|
OneToMany |
- Species with no ortholog for CCNA1:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for CCNA1 Gene
Paralogs for CCNA1 Gene
(1) SIMAP similar genes for CCNA1 Gene using alignment to 2 proteins:
Variants for CCNA1 Gene
| SNP ID | Clin | Chr 13 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs947316 | -- | 36,440,375(-) | CCAAA(C/T)ATAGT | intron-variant | |
| rs947317 | -- | 36,437,907(-) | GGTAC(C/G)ATCAG | intron-variant | |
| rs2282411 | -- | 36,440,229(-) | TTTTA(C/T)GCTCC | intron-variant | |
| rs3814803 | -- | 36,430,827(-) | ATTGC(C/T)GCAAC | upstream-variant-2KB | |
| rs3814804 | -- | 36,430,650(-) | ACTCC(G/T)TCTGG | upstream-variant-2KB |
Residual Variation Intolerance Score:
23.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.16;
23.38% of all genes are more intolerant (likely to be disease-causing)
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for CCNA1 Gene
Disorders for CCNA1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| myeloid leukemia |
|
|
| leukemia, acute promyelocytic, somatic |
|
|
| leukemia, acute myeloid |
|
|
Search CCNA1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for CCNA1
No data available for UniProtKB/Swiss-Prot and Genatlas for CCNA1 Gene
Publications for CCNA1 Gene
- Characterization of a second human cyclin A that is highly expressed in testis and in several leukemic cell lines. (PMID: 9041194) Yang R. … Koeffler H.P. (Cancer Res. 1997) 2 3 4 23 67
- KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation. (PMID: 20457893) Hsia D.A. … Izumiya Y. (Proc. Natl. Acad. Sci. U.S.A. 2010) 3 23
- Post-translational modification of cyclin A1 is associated with staurosporine and TNFalpha induced apoptosis in leukemic cells. (PMID: 18787932) Ekberg J. … Persson J.L. (Mol. Cell. Biochem. 2009) 3 23
- Distinct properties of cyclin-dependent kinase complexes containing cyclin A1 and cyclin A2. (PMID: 19056339) Joshi A.R. … Wolgemuth D.J. (Biochem. Biophys. Res. Commun. 2009) 3 23
- [Expression of cyclin A1 mRNA in patients with myelodysplastic syndrome and its clinical significance]. (PMID: 19379570) Jia J.S. … Xu S.R. (Zhongguo Shi Yan Xue Ye Xue Za Zhi 2009) 3 23
Products for CCNA1 Gene
- R&D Systems Antibodies for CCNA1 (Cyclin A1)
- Browse R&D Systems for Human Recombinant Proteins
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- OriGene qPCR primer pairs for CCNA1
- OriGene qPCR primer pairs and template standards for CCNA1
- OriGene CRISPR knockouts for CCNA1
- OriGene clones in human for CCNA1
- OriGene ORF clones in human,mouse,rat for CCNA1
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- Protein Production Services
- Transfection Reagents
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- Novus Biologicals Antibodies for CCNA1
- Novus Biologicals proteins and lysates for CCNA1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for CCNA1
- Cloud-Clone Corp. Proteins for CCNA1
- Cloud-Clone Corp Assay Kits for CCNA1
- antibodies-online Antibodies for CCNA1: See all 93
- antibodies-online Kits for CCNA1: See all 6
- antibodies-online Proteins for CCNA1: See all 8
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for CCNA1
- Search GeneTex for Proteins for CCNA1
- ViGene Biosciences adenoviral particle packaged cDNA for CCNA1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CCNA1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CCNA1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CCNA1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CCNA1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CCNA1 gene
- Search ViGene Biosciences for CCNA1
- Search ViGene Biosciences for CCNA1
- Santa Cruz Biotechnology (SCBT) Antibodies for CCNA1
- Search Santa Cruz Biotechnology (SCBT) for CCNA1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CCNA1
Sources for CCNA1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon