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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CCL4L1 Gene

protein-coding   GIFtS: 51
GCID: GC17P034538

chemokine (C-C motif) ligand 4-like 1

(Previous names: small inducible cytokine A4-like, chemokine (C-C motif)...)
(Previous symbols: SCYA4L, CCL4L)
 Explore 3 diseases affiliated with
CCL4L1 via our new
 Human Malady Compendium 
Biological research products
for CCL4L1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Chemokine (C-C Motif) Ligand 4-Like 11 2     MIP-1-Beta1
CCL4L1 2 3 5     Chemokine (C-C Motif) Ligand 4-Like1
LAG-11 2 3     Small Inducible Cytokine A4-Like1
SCYA4L1 2 5     C-C Motif Chemokine 4-Like2
LAG12 3 5     Macrophage Inflammatory Protein-1b22
AT744.21 2     SCYA4L13
Lymphocyte Activation Gene 1 Protein2 3     SCYA4L23
Macrophage Inflammatory Protein 1-Beta2 3     Small-Inducible Cytokine A4-Like3
Monocyte Adherence-Induced Protein 5-Alpha2 3     

External Ids:    HGNC: 106311   Entrez Gene: 95602   Ensembl: ENSG000002050207   OMIM: 6037825   UniProtKB: Q8NHW43   

Export aliases for CCL4L1 gene to outside databases

Previous GC identifers: GC17P034785 GC17P031664 GC17P031564 GC17P030726


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CCL4L1:
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted
proteins involved in immunoregulatory and inflammatory processes. This protein is similar to CCL4 which inhibits HIV
entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals; most
individuals have 1-5 copies in the diploid genome, although rare individuals do not contain this gene at all. The
human genome reference assembly contains two copies of this gene. This record represents the more centromeric gene.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CC4L_HUMAN, Q8NHW4
Function: Chemokine that induces chemotaxis of cells expressing CCR5 or CCR1. Inhibits HIV replication in peripheral
blood monocytes that express CCR5

Gene Wiki entry for CCL4L1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010799.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CCL4L1 gene promoter:
         HOXA9B   HOXA9   AML1a   Pbx1a   AP-1   LCR-F1   Ik-3   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCL4L1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CCL4L1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCL4L1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q12   Ensembl cytogenetic band:  17q12   HGNC cytogenetic band: 17q12

CCL4L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCL4L1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P034538:  view genomic region     (about GC identifiers)

Start:
34,538,310 bp from pter      End:
34,540,280 bp from pter
Size:
1,971 bases      Orientation:
plus strand

1 alternative location:
Chr17+,PATCHES 34,552,677-34,554,484     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CC4L_HUMAN, Q8NHW4 (See protein sequence)
Recommended Name: C-C motif chemokine 4-like precursor  
Size: 92 amino acids; 10166 Da
Subunit: Interacts with CCR5
Subcellular location: Secreted (By similarity)
Secondary accessions: B2RUZ3 B7ZMA8 Q50EM1 Q50EM2 Q50EM3 Q50EM4 Q50EM5 Q50EM6 Q50EM7 Q50EM8 Q569J2
Q6NSB0
Alternative splicing: 10 isoforms:  Q8NHW4-1   Q8NHW4-2   Q8NHW4-3   Q8NHW4-4   Q8NHW4-5   Q8NHW4-6   Q8NHW4-7   Q8NHW4-8   
Q8NHW4-9   Q8NHW4-10   

Explore the universe of human proteins at neXtProt for CCL4L1: NX_Q8NHW4

CCL4L1 Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).

REFSEQ proteins: NP_001001435.1  
ENSEMBL proteins: 
 ENSP00000367601   ENSP00000373720   ENSP00000465568   ENSP00000466720   ENSP00000467722  
 ENSP00000383538   ENSP00000467085   ENSP00000467658   ENSP00000468405   ENSP00000405533  
 ENSP00000367603   ENSP00000351606  

Human Recombinant Protein Products: 
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R&D Systems Recombinant & Natural Proteins for CCL4L1 (CCL4L1/LAG-1)
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein: CCL4L1
OriGene Protein Over-expression Lysate: CCL4L1
OriGene Custom Protein Services for CCL4L1 
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Novus Biologicals CCL4L1 Protein
Novus Biologicals CCL4L1 Lysate
Browse Sino Biological Recombinant Proteins
ProSpec Recombinant Protein for CCL4L1
Uscn Proteins for CCL4L1

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region ----
GO:0005615extracellular space IEA--


CCL4L1 for ontologies           About GeneDecksing



CCL4L1 Antibody Products: 
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Uscn ELISAs and CLIAs for CCL4L1


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CCL4L1 for domains           About GeneDecksing

2 InterPro domains/families:
 IPR000827 Chemokine_CC_CS
 IPR001811 Chemokine_IL8-like_dom

Graphical View of Domain Structure for InterPro Entry Q8NHW4

ProtoNet protein and cluster: Q8NHW4

1 Blocks protein family: IPB000827 Small chemokine

UniProtKB/Swiss-Prot: CC4L_HUMAN, Q8NHW4
Similarity: Belongs to the intercrine beta (chemokine CC) family


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

     UniProtKB/Swiss-Prot: CC4L_HUMAN, Q8NHW4
Function: Chemokine that induces chemotaxis of cells expressing CCR5 or CCR1. Inhibits HIV replication in peripheral
blood monocytes that express CCR5

miRNA
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Browse MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CCL4L1
1 QIAGEN miScript miRNA Assays for microRNA that regulate CCL4L1:
hsa-miR-3919
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
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OriGene siRNA: CCL4L1
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCL4L1

Gene Editing
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Sino Biological Human cDNA Clone for CCL4L1
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCL4L1 

Cell Line
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Search LifeMap BioReagents cell lines for CCL4L1

In Situ Assay
Products:
   

 
Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CCL4L1

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008009chemokine activity IEA--


CCL4L1 for ontologies           About GeneDecksing



(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/8 super-pathways (see all 8About this table 
See pathways by source

Super-pathwaycontained gene-specific pathways
1PEDF Induced Signaling
8/9 pathways (see all 9)
PEDF Induced Signaling1.00
RAR-Gamma-RXR-Alpha Degradation0.54
MIF Mediated Glucocorticoid Regulation0.73
STAT3 Pathway0.47
MIF Regulation of Innate Immune Cells0.71
Endothelin-1 Signaling Pathway0.44
IL-6 Pathway0.61
Cytokine-cytokine receptor interaction0.26
2Rho Family GTPases
Rho Family GTPases1.00
Molecular Mechanisms of Cancer0.51
ERK Signaling0.61
3PAK Pathway
PAK Pathway1.00
Antioxidant Action of Vitamin-C0.56
4Akt Signaling
Akt Signaling1.00
p38 Signaling0.60
5Chemokine Signaling
Chemokine Signaling1.00
Chemokine signaling pathway0.33

Pathway sources
See GeneCards unified pathways
Show all pathways

5/17 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CCL4L1 (see all 17)
    Endothelin-1 Signaling Pathway
Molecular Mechanisms of Cancer
Antioxidant Action of Vitamin-C
Transendothelial Migration of Leukocytes
MIF Mediated Glucocorticoid Regulation

1 BioSystems Pathway for CCL4L1 
    IL12-mediated signaling events


3         Kegg Pathways  (Kegg details for CCL4L1):
    Cytokine-cytokine receptor interaction
Chemokine signaling pathway
Cytosolic DNA-sensing pathway


CCL4L1 for pathways           About GeneDecksing

Interactions:

    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CCL4L1

STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

5/19 Interacting proteins for CCL4L1 (ENSP000004055334) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
InteractantInteraction Details
GeneCardExternal ID(s)
CCR1ENSP000002961404STRING: ENSP00000296140
CCR10ENSP000003325044STRING: ENSP00000332504
CCR2ENSP000002923014STRING: ENSP00000292301
CCR3ENSP000003500034STRING: ENSP00000350003
CCR4ENSP000003326594STRING: ENSP00000332659
About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006935chemotaxis IEA--
GO:0006954inflammatory response IEA--
GO:0006955immune response IEA--


CCL4L1 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CCL4L1
Search CenterWatch for drugs/clinical trials and news about CCL4L1 / CC4L 

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CCL4L1 gene: 
NM_001001435.2  

Unigene Cluster for CCL4L1:

Chemokine (C-C motif) ligand 4-like 1
Hs.515183  [show with all ESTs]
Unigene Representative Sequence: CD522041
12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000378350 ENST00000389068 ENST00000588929 ENST00000589079 ENST00000589336
ENST00000400702 ENST00000591167 ENST00000586598 ENST00000591637 ENST00000444414(uc010cuj.3 uc002hlh.1 uc002hlj.1 uc002hli.1 uc010cuk.1)
ENST00000378352 ENST00000358756

miRNA
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hsa-miR-3919
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
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OriGene shRNA RFP: CCL4L1
OriGene siRNA: CCL4L1
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCL4L1
Clone
Products:
     
OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCL4L1
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCL4L1 
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OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCL4L1
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  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCL4L1
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCL4L1

Additional cDNA sequence: 

AY766447.1 BC130456.1 BC146944.1 BC146958.1 

10 DOTS entries:

DT.100044914  DT.100044255  DT.100890240  DT.97766642  DT.100890230  DT.453194  DT.120948254  DT.95267994 
DT.100890234  DT.86854556 

24/158 AceView cDNA sequences (see all 158):

AA362183 AA382176 CD368437 BG236084 AI301910 BU626856 AI688323 BI833216 
T35987 NM_001001435 CD369184 AI436708 CD368561 AA362193 CD366138 BM458425 
AA362243 CD369529 AI928485 NM_207007 CD641361 CD640240 AI688619 CD559380 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CCL4L1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTTTTCATA

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)

About this image
See CCL4L1 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.515183

UniProtKB/Swiss-Prot: CC4L_HUMAN, Q8NHW4
Tissue specificity: Detected in B-cells

    SABiosciences Custom PCR Arrays for CCL4L1
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In Situ
Assay Products:
 

 
Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CCL4L1

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for CCL4L1 gene from 1/4 species (see all 4)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
zebrafish
(Danio rerio)
Actinopterygii zgc:1937066
si:dkeyp-59a8.36
(see all 6)
si:dkeyp-59a8.3
(see all 6)
36(a)
33(a)
(see all 6)
many ↔ many
many ↔ many
(see all 6)
25(25902180-25904281)
20(38310380-38311158)


ENSEMBL Gene Tree for CCL4L1 (if available)
TreeFam Gene Tree for CCL4L1 (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for CCL4L1 gene
CCL4L21 2  CCL152  CCL162  CCL22  CCL142  CCL242  CCL112  CCL72  
CCL3L12  CCL52  CCL232  CCL3L32  CCL42  CCL82  CCL132  CCL262  
CCL32  CCL182  
18/29 SIMAP similar genes for CCL4L1 using alignment to 3 protein entries:     CC4L_HUMAN (see all proteins) (see all similar genes):
LOC728835    CCL4L2    CCL4    CCL3L1    CCL3    CCL3L3
CCL14    CCL5    CCL11    CCL18    CCL2    CCL13
CCL26    CCL7    MCP-3    CCL16    CCL8    CCL15

CCL4L1 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

UniProtKB/Swiss-Prot: CC4L_HUMAN, Q8NHW4
Polymorphism: The copy number of the CC4L1 gene varies among individuals; most individuals have 1 to 6 copies in the
diploid genome


12/14 NCBI SNPs in CCL4L1 are shown (see all 14    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 17 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1421006391,2
C--34538069(+) TTGTTC/TTTGGG 1 -- us2k10--------
rs1996294971,2
F--34539815(+) CACAGG/CCAAGG 1 -- int11Minor allele frequency- C:0.02EU 205
rs1488004371,2
C--34539900(+) AAAGAG/AGCAAG 2 /S /G mis11Minor allele frequency- A:0.00NA 3136
rs1415591591,2
C,F--34539901(+) AAGAGG/TCAAGC 2 G V mis11Minor allele frequency- T:0.00NA 3146
rs1508842571,2
C,F--34539915(+) TCTGCG/ACTGAC 2 /T /A mis12Minor allele frequency- A:0.00NA EU 3739
rs2013899241,2
----34536822(+) CAATTA/GTCCTC 1 -- us2k10--------
rs1450756451,2
----34537762(+) TGAGCA/GCCATC 1 -- us2k10--------
rs2015075101,2
----34538113(+) TGAACA/CCTCCA 1 -- us2k10--------
rs1475829271,2
----34537887(+) TGGTAC/TAAGGT 1 -- us2k10--------
rs1458863951,2
----34538680(+) TTCTAG/TTCATG 1 -- int10--------
rs2009753761,2
----34539235(+) TCCTCA/GCAACT 2 H R mis10--------
rs1453157501,2
----34539745(+) GCTCCA/GGGAAG 1 -- int10--------

HapMap Linkage Disequilibrium report for CCL4L1 (34538310 - 34540280 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 25 variations for CCL4L1
     15/25 CNVs (see all 25): 77573 37558 7154 88435 8841 72884 88444 30824 35451 35450 88441 5003 77579 77581 3142
Human Gene Mutation Database (HGMD): CCL4L1

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCL4L1
DNA2.0 Custom Variant and Variant Library Synthesis for CCL4L1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CCL4L1 for disorders           About GeneDecksing

OMIM gene information: 603782    OMIM disorders: --

3 diseases for CCL4L1:    About MalaCards
hiv/aids    psoriasis    immunodeficiency

Human Genome Epidemiology (HuGE) Navigator: CCL4L1 (5 documents)

Export disorders for CCL4L1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for CCL4L1 gene, integrated from 9 sources (see all 33):
(articles sorted by number of sources associating them with CCL4L1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. CCL3L1 and CCL4L1 chemokine genes are located in a segmental duplication at chromosome 17q12. (PubMed id 15028295)1, 2, 3 Modi W.S. (2004)
  2. CCL3L1 and CCL4L1: variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infection. (PubMed id 17330138)1, 2, 9 Shao W....Kaslow R.A. (2007)
  3. Multiple products derived from two CCL4 loci: high incidence of a new polymorphism in HIV+ patients. (PubMed id 15843566)1, 2, 9 Colobran R.... Juan M. (2005)
  4. Independent expression of the two paralogous CCL4 genes in monocytes and B lymphocytes. (PubMed id 14673550)1, 2 Lu J.... Sloan S.R. (2004)
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  6. The human MIP-1beta chemokine is encoded by two paralogous genes, ACT-2 and LAG-1. (PubMed id 11685466)1, 2 Modi W.S....Sanford M. (2001)
  7. A YAC contig of the human CC chemokine genes clustered on chromosome 17q11.2. (PubMed id 8661057)1, 3 Naruse K....Miura R. (1996)
  8. Two inflammatory mediator cytokine genes are closely linked and variably amplified on chromosome 17q. (PubMed id 1972563)1, 3 Irving S.G.... Kelly K. (1990)
  9. Functional redundancy of the human CCL4 and CCL4L1 chemokine genes. (PubMed id 15240137)2, 9 Howard O.M....Modi W.S. (2004)
  10. Copy number variation in the CCL4L gene is associated with susceptibility to acute rejection in lung transplantation. (PubMed id 19148142)1, 9 Colobran R....Palou E. (2009)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 9560 HGNC: 10631 AceView: LOC388440 Ensembl:ENSG00000205020 euGenes: HUgn9560
ECgene: CCL4L1 Kegg: 9560 H-InvDB: CCL4L1

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PharmGKB entry for CCL4L1 Pharmacogenomics, SNPs, Pathways

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