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CCL4 Gene

protein-coding   GIFtS: 63
GCID: GC17P034431

Chemokine (C-C Motif) Ligand 4

(Previous name: small inducible cytokine A4 (homologous to mouse Mip-1b))
(Previous symbols: LAG1, SCYA4)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Chemokine (C-C Motif) Ligand 41 2     PAT 7442 3
SCYA41 2 3 5     T-Cell Activation Protein 22 3
LAG11 2 3     ACT22 5
MIP1B2 3 5     AT744.12 5
Small Inducible Cytokine A4 (Homologous To Mouse Mip-1b)1 2     G-262
Lymphocyte Activation Gene 1 Protein2 3     MIP1B12
Macrophage Inflammatory Protein 1-Beta2 3     SCYA22
HC212 3     C-C Motif Chemokine 42
LAG-12 3     Secreted Protein G-262
MIP-1-beta2 3     ACT-23
MIP-1-beta(1-69)2 3     Protein H4003
SIS-gamma2 3     Small-Inducible Cytokine A43
G-26 T-Lymphocyte-Secreted Protein2 3     

External Ids:    HGNC: 106301   Entrez Gene: 63512   Ensembl: ENSG000001292777   OMIM: 1822845   UniProtKB: P132363   
ORGUL members:         

Export aliases for CCL4 gene to outside databases

Previous GC identifers: GC17P034201 GC17P036466 GC17P034279 GC17P034576 GC17P031421 GC17P030617


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CCL4 Gene:
The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors
produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions.
(provided by RefSeq, Dec 2012)

GeneCards Summary for CCL4 Gene:
CCL4 (chemokine (C-C motif) ligand 4) is a protein-coding gene. Diseases associated with CCL4 include idiopathic steroid-sensitive nephrotic syndrome, and stachybotrys chartarum. GO annotations related to this gene include identical protein binding and chemokine activity. An important paralog of this gene is CCL15.

UniProtKB/Swiss-Prot: CCL4_HUMAN, P13236
Function: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive
factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains
of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the
abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the
CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B

Gene Wiki entry for CCL4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NC_018928.2  NT_010783.16  NT_187614.1  NT_187661.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the CCL4 gene promoter:
         CREB   AML1a   deltaCREB   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCL4 promoter sequence
   Search Chromatin IP Primers for CCL4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCL4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q12   Ensembl cytogenetic band:  17q12   HGNC cytogenetic band: 17q21-q23

CCL4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCL4 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P034431:  view genomic region     (about GC identifiers)

Start:
34,430,983 bp from pter      End:
34,433,014 bp from pter
Size:
2,032 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CCL4_HUMAN, P13236 (See protein sequence)
Recommended Name: C-C motif chemokine 4 precursor  
Size: 92 amino acids; 10212 Da
Subunit: Homodimer and heterodimer of MIP-1-alpha(4-69) and MIP-1-beta(3-69)
Caution: Was originally (PubMed:9521068) thought to be a ligand for CCR8
Selected PDB 3D structures from and Proteopedia for CCL4 (see all 7):
1HUM (3D)        1HUN (3D)        1JE4 (3D)        2FFK (3D)        2FIN (3D)        2X6L (3D)    
Secondary accessions: P22617 Q13704 Q3SXL8 Q6FGI8

Explore the universe of human proteins at neXtProt for CCL4: NX_P13236

Post-translational modifications: 

  • N-terminal processed form MIP-1-beta(3-69) is produced by proteolytic cleavage after secretion from peripheral
    blood lymphocytes1
  • Modification sites at neXtProt
  • REFSEQ proteins: NP_002975.1  
    ENSEMBL proteins: 
     ENSP00000250151   ENSP00000378004  
    Reactome Protein details: P13236

    CCL4 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for CCL4 (CCL4/MIP-1 beta)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for CCL4
    OriGene Protein Over-expression Lysate for CCL4
    OriGene MassSpec for CCL4
    OriGene Custom Protein Services for CCL4
    GenScript Purified and Recombinant Proteins for CCL4
    Novus Biologicals CCL4 Proteins
    Novus Biologicals CCL4 Lysates
    Sino Biological Recombinant Protein for CCL4
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for CCL4
    Browse Proteins at Cloud-Clone Corp.

    CCL4 Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of CCL4
    R&D Systems Antibodies for CCL4 (CCL4/MIP-1 beta)
    OriGene Antibodies for CCL4
    OriGene Custom Antibody Services for CCL4
    Novus Biologicals CCL4 Antibodies
    Abcam antibodies for CCL4 (P13236, Q8NHW4)
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for CCL4
    LSBio Antibodies in human, mouse, rat for CCL4

    CCL4 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CCL4
    R&D Systems Flow Cytometry Kits for CCL4 (CCL4/MIP-1 beta)         (see all)
    GenScript Custom Assay Services for CCL4
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ENDOLIG: Endogenous ligands
    CCL: Chemokine ligands

    2 InterPro protein domains:
     IPR000827 Chemokine_CC_CS
     IPR001811 Chemokine_IL8-like_dom

    Graphical View of Domain Structure for InterPro Entry P13236

    ProtoNet protein and cluster: P13236

    1 Blocks protein domain: IPB000827 Small chemokine

    UniProtKB/Swiss-Prot: CCL4_HUMAN, P13236
    Similarity: Belongs to the intercrine beta (chemokine CC) family


    CCL4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CCL4_HUMAN, P13236
    Function: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive
    factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains
    of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the
    abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the
    CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B
    Induction: By mitogens

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005125cytokine activity TAS2462251
    GO:0005515protein binding IPI--
    GO:0008009chemokine activity IEA--
    GO:0031726CCR1 chemokine receptor binding IPI7545673
    GO:0031730CCR5 chemokine receptor binding IPI10679098
         
    CCL4 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCL4
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCL4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCL4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CCL4

    miRNA
    Products:
        
    miRTarBase miRNAs that target CCL4:
    hsa-mir-195-5p (MIRT004669)

    Block miRNA regulation of human, mouse, rat CCL4 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate CCL4:
    hsa-miR-125a-3p hsa-miR-3919 hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidCCL4 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CCL4
    Predesigned siRNA for gene silencing in human, mouse, rat CCL4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CCL4

    Clone
    Products:
         
    OriGene clones in human, mouse for CCL4 (see all 6)
    OriGene ORF clones in mouse, rat for CCL4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CCL4 (NM_002984)
    Sino Biological Human cDNA Clone for CCL4
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCL4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCL4

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CCL4
    Browse ESI BIO Cell Lines and PureStem Progenitors for CCL4 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCL4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CCL4_HUMAN, P13236: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    nucleus2
    cytoskeleton1
    cytosol1
    plasma membrane1
    vacuole1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space IEA--

    CCL4 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CCL4 About   (see all 18)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1PEDF Induced Signaling
    MIF Regulation of Innate Immune Cells0.94
    NFAT Signaling and Lymphocyte Interactions0.57
    MIF Mediated Glucocorticoid Regulation0.94
    PGC1Alpha Pathway0.51
    PEDF Induced Signaling0.73
    STAT3 Pathway0.47
    all-trans-Retinoic Acid Signaling in Brain0.71
    Endothelin-1 Signaling Pathway0.46
    2Toll-like receptor signaling pathway
    Toll-like receptor signaling pathway0.94
    Regulation of toll-like receptor signaling pathway0.93
    Toll-like receptor signaling pathway0.94
    3Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions
    Chemokine receptors bind chemokines0.81
    Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions0.81
    4Chemokine Signaling
    Chemokine signaling pathway0.33
    Chemokine Signaling0.33
    5TGF-Beta Pathway
    TGF-Beta Pathway0.60
    JNK Pathway0.51
    MAPK Family Pathway0.60
    Regulation of eIF4 and p70S6K0.43
    JAK-STAT Pathway0.57
    SOCS Pathway0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 R&D Systems Pathways for CCL4
        Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions
    IL-15 Signaling and its Primary Biological Effects in Different Immune Cell Types

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for CCL4 (see all 28)
        Endothelin-1 Signaling Pathway
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C
    NFAT Signaling and Lymphocyte Interactions
    JNK Pathway

    1 GeneGo (Thomson Reuters) Pathway for CCL4
        Apoptosis and survival APRIL and BAFF signaling

    3 BioSystems Pathways for CCL4
        Toll-like receptor signaling pathway
    IL12-mediated signaling events
    Regulation of toll-like receptor signaling pathway


    1 Reactome Pathway for CCL4
        Chemokine receptors bind chemokines


    Selected Kegg Pathways  (Kegg details for CCL4) (see all 6):
        Cytokine-cytokine receptor interaction
    Chemokine signaling pathway
    NF-kappa B signaling pathway
    Toll-like receptor signaling pathway
    Cytosolic DNA-sensing pathway


    CCL4 for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Arrays including CCL4 (see all 14): 
              HIV Host Response in human mouse rat
              G-Protein-Coupled Receptor Signaling PathwayFinder in human mouse rat
              Antiviral Response in human mouse rat
              Inflammatory Response & Autoimmunity in human mouse rat
              T-cell & B-cell Activation in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for CCL4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for CCL4 (P132361, 2, 3 ENSP000002501514) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCR5P516811, 3, ENSP000002923034EBI-6625160,EBI-489374 I2D: score=3 STRING: ENSP00000292303
    IDEP147352, 3, ENSP000002659864MINT-8087616 I2D: score=1 STRING: ENSP00000265986
    CCR1P322463, ENSP000002961404I2D: score=5 STRING: ENSP00000296140
    ACKR2O005903, ENSP000002731454I2D: score=4 STRING: ENSP00000273145
    CCL3P101473, ENSP000002252454I2D: score=3 STRING: ENSP00000225245
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006928cellular component movement TAS9759849
    GO:0006935chemotaxis ----
    GO:0006954inflammatory response IEA--
    GO:0006955immune response IEA--
    GO:0007155cell adhesion TAS10929056

    CCL4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CCL4

    Selected Novoseek inferred chemical compound relationships for CCL4 gene (see all 67)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    rantes 97 722 10888363 (7), 11861332 (6), 9746565 (6), 16924394 (5) (see all 99)
    ccl3 90.8 130 12960284 (3), 15585374 (3), 16773571 (3), 19074730 (3) (see all 74)
    ccl4 84.6 232 14761932 (7), 15240137 (6), 15843566 (4), 14673550 (4) (see all 99)
    mip 1alpha 84.3 23 16518599 (5), 18403790 (4), 11097208 (2), 9343222 (1) (see all 12)
    groalpha 78.1 15 10437780 (2), 16542377 (2), 10419917 (1), 17228323 (1) (see all 13)
    tarc 76.6 17 10540332 (3), 9521068 (2), 15941911 (1), 9153236 (1) (see all 12)
    grogamma 71 3 10467937 (2), 11808935 (1)
    larc 68.8 9 18492658 (3), 9153236 (1), 9169480 (1), 10449163 (1) (see all 7)
    mcp 1 59.6 5 10559777 (2), 15660413 (1), 17993576 (1), 11683586 (1)
    mdms 58.3 7 16857988 (1), 9870313 (1), 10082122 (1), 11839143 (1)



    CCL4 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CCL4 gene: 
    NM_002984.2  

    Unigene Cluster for CCL4:

    Chemokine (C-C motif) ligand 4
    Hs.75703  [show with all ESTs]
    Unigene Representative Sequence: CD521853
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000250151(uc002hkw.1) ENST00000394495(uc002hkx.1) ENST00000591883

    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CCL4 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate CCL4:
    hsa-miR-125a-3p hsa-miR-3919 hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidCCL4 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CCL4
    Predesigned siRNA for gene silencing in human, mouse, rat CCL4
    Clone
    Products:
         
    OriGene clones in human, mouse for CCL4 (see all 6)
    OriGene ORF clones in mouse, rat for CCL4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CCL4 (NM_002984)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCL4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCL4
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CCL4
    OriGene qSTAR qPCR primer pairs in human, mouse for CCL4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCL4
      QuantiTect SYBR Green Assays in human, mouse, rat CCL4
      QuantiFast Probe-based Assays in human, mouse, rat CCL4

    Additional mRNA sequence: 

    AY312578.1 AY766446.1 AY766448.1 BC104226.1 BC104227.1 BC107433.1 CR542119.1 J04130.1 
    M23502.1 M25316.1 M57503.1 X16166.1 X53683.1 

    12 DOTS entries:

    DT.100044914  DT.100044255  DT.97766642  DT.100890234  DT.86854556  DT.100890235  DT.100762795  DT.120948312 
    DT.95267994  DT.95267995  DT.120948253  DT.453194 

    Selected AceView cDNA sequences (see all 177):

    AA362350 T29074 AA362359 BE326709 AI341064 CR610625 AI359523 AI862912 
    AA362287 AI343539 BM543715 AY312578 BU753465 AW059871 CD638976 BV203915 
    CA748764 CD522340 BV203909 BQ007461 CD521723 AI950224 CD521196 CD522904 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CCL4 expression in normal human tissues (normalized intensities)      CCL4 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATAACACAT
    CCL4 Expression
    About this image


    CCL4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 4 entries
             Bone Marrow
             Bone marrow-derived mesenchymal stem cells (Stempeucel)
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Natural Killer Cells Peripheral Blood
     
     Ovary (Reproductive System)
             Secondary follicles
     
     Mesenchymal Stem Cells
             Bone marrow-derived mesenchymal stem cells (Stempeucel)
     
     Lateral Plate Mesoderm (Gastrulation Derivatives)
             Hematopoietic Stem Cells Aorta-Gonad-Mesonephros
    CCL4 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

    SOURCE GeneReport for Unigene cluster: Hs.75703
        Pathway & Disease-focused RT2 Profiler PCR Arrays including CCL4 (see all 14): 
              HIV Host Response in human mouse rat
              G-Protein-Coupled Receptor Signaling PathwayFinder in human mouse rat
              Antiviral Response in human mouse rat
              Inflammatory Response & Autoimmunity in human mouse rat
              T-cell & B-cell Activation in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CCL4
    OriGene qSTAR qPCR primer pairs in human, mouse for CCL4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCL4
    QuantiTect SYBR Green Assays in human, mouse, rat CCL4
    QuantiFast Probe-based Assays in human, mouse, rat CCL4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCL4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

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    This gene was present in the common ancestor of chordates.

    Orthologs for CCL4 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccl41 , 5 chemokine (C-C motif) ligand 41, 5 81.88(n)1
    76.09(a)1
      11 (51.09 cM)5
    203031  NM_013652.21  NP_038680.11 
     836625845 
    chicken
    (Gallus gallus)
    Aves CCL41 chemokine (C-C motif) ligand 4 59.93(n)
    50.56(a)
      395468  NM_204720.1  NP_990051.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ZGC:1937066
    chemokine CCL-C25y-like (LOC100000034), mRNA
    33(a)
    1 → many
    25(25902180-25904281) ENSDARG00000070378


    ENSEMBL Gene Tree for CCL4 (if available)
    TreeFam Gene Tree for CCL4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CCL4 gene
    CCL152  CCL162  CCL142  CCL4L12  CCL3L12  CCL4L22  CCL262  CCL32  
    CCL52  CCL232  CCL3L32  CCL182  CCL15-CCL142  
    Selected SIMAP similar genes for CCL4 using alignment to 3 protein entries:     CCL4_HUMAN (see all proteins) (see all similar genes):
    CCL4L2    LOC728835    CCL4L1    CCL3L1    CCL3    CCL14
    CCL5    CCL3L3    CCL11    CCL18    CCL7    MCP-3
    CCL2    CCL16    CCL26    CCL8    CCL13    CCL22

    CCL4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

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    3 SNPs for CCL4    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs17191521,2,4
    ----see VAR_0592112 mis40--------
    rs96357711,2,4
    ----see VAR_0487022 mis40--------
    rs11307501,2,4
    ----see VAR_0487032 mis40--------

    HapMap Linkage Disequilibrium report for CCL4 (34430983 - 34433014 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CCL4 (see all 29):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2664544CNV Deletion23128226
    esv2715876CNV Deletion23290073
    esv2670934CNV Deletion23128226
    nsv471396CNV Duplication19718026
    nsv833427CNV Loss17160897
    esv33107CNV Loss17666407
    dgv178n21CNV Loss19592680
    dgv122e55CNV Gain17911159
    dgv522n67CNV Gain20364138
    dgv3144n71CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing CCL4
    DNA2.0 Custom Variant and Variant Library Synthesis for CCL4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 182284    OMIM disorders: --

    Selected diseases for CCL4 (see all 136):    About MalaCards
    idiopathic steroid-sensitive nephrotic syndrome    stachybotrys chartarum    retinal vasculitis    lyme disease
    idiopathic pulmonary alveolar proteinosis    erdheim-chester disease    meconium aspiration syndrome    alexithymia
    relapsing polychondritis    castleman's disease    toxic shock syndrome    crescentic glomerulonephritis
    periapical granuloma    pulmonary alveolar proteinosis    measles    eosinophilic pneumonia
    tuberculosis    breast cyst    cerebral malaria    endocervicitis

    1 disease from the University of Copenhagen DISEASES database for CCL4:
    Human immunodeficiency virus infectious disease

    CCL4 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Selected Novoseek inferred disease relationships for CCL4 gene (see all 74)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    necrosis 67.3 152 14726627 (2), 14586377 (2), 18622277 (2), 10496934 (2) (see all 99)
    immunodeficiency 66.9 34 10979927 (2), 9343222 (1), 9359702 (1), 12427015 (1) (see all 29)
    inflammation 63.1 15 9841832 (2), 11097208 (1), 12548712 (1), 14761932 (1) (see all 13)
    hiv infections 61.4 17 9732062 (2), 9649315 (1), 10461827 (1), 11120614 (1) (see all 14)
    virus infection 43.2 8 10501489 (1), 19155475 (1), 17547763 (1), 19846870 (1) (see all 8)
    tumors 43.2 132 15126779 (5), 14586377 (2), 18622277 (2), 12473593 (2) (see all 99)
    periapical granuloma 39.6 2 11683586 (2)
    aids 37.6 17 9466518 (3), 9420304 (2), 10618285 (1), 16773571 (1) (see all 10)
    fibrosis idiopathic pulmonary 32.6 5 11031344 (1), 10384061 (1), 19046553 (1)
    viremia 27.5 1 18234797 (1)

    Genetic Association Database (GAD): CCL4
    Human Genome Epidemiology (HuGE) Navigator: CCL4 (17 documents)

    Export disorders for CCL4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for CCL4 gene, integrated from 10 sources (see all 951) (see top 10):
    (articles sorted by number of sources associating them with CCL4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. CCL3L1 and CCL4L1: variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infection. (PubMed id 17330138)1, 4, 9 Shao W.... Kaslow R.A. (Genes Immun. 2007)
    2. Multiple products derived from two CCL4 loci: high incidence of a new polymorphism in HIV+ patients. (PubMed id 15843566)1, 2, 9 Colobran R.... Juan M. (J. Immunol. 2005)
    3. Macrophage inflammatory protein-1. (PubMed id 12401480)1, 2, 9 Menten P.... Van Damme J. (Cytokine Growth Factor Rev. 2002)
    4. Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor. (PubMed id 9521068)1, 2, 9 Bernardini G....Napolitano M. (Eur. J. Immunol. 1998)
    5. The assignment of chemokine-chemokine receptor pairs: TARC and MIP-1 beta are not ligands for human CC-chemokine receptor 8. (PubMed id 10540332)1, 2, 9 Garlisi C.G....Umland S.P. (Eur. J. Immunol. 1999)
    6. Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment. (PubMed id 20056178)1, 4 Segat L....Crovella S. (Vaccine 2010)
    7. Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. (PubMed id 20503287)1, 4 Schuurhof A....Janssen R. (Pediatr. Pulmonol. 2010)
    8. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923)1, 4 Siezen C.L....Janssen R. (Pediatr. Infect. Dis. J. 2009)
    9. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. (PubMed id 17703412)1, 4 Janssen R....Hoebee B. (J. Infect. Dis. 2007)
    10. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)1, 2 Zody M.C.... Nusbaum C. (Nature 2006)
    11. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    12. Natural truncation of the chemokine MIP-1beta/CCL4 affects receptor specificity but not anti-HIV-1 activity. (PubMed id 12070155)1, 2 Guan E.... Norcross M.A. (J. Biol. Chem. 2002)
    13. No association between presenilin 1 (PS1) intronic polymorphism and sporadic Alzheimer's disease in Koreans. (PubMed id 11129109)1, 4 Kim K.W....Woo J.I. (J Neural Transm 2000)
    14. Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. (PubMed id 8525373)1, 2 Cocchi F....Lusso P. (Science 1995)
    15. High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMR. (PubMed id 8134838)1, 2 Lodi P.J.... Clore G.M. (Science 1994)
    16. The gene encoding the Act-2 cytokine. Genomic structure, HTLV-I/Tax responsiveness of 5' upstream sequences, and chromosomal localization. (PubMed id 1894635)1, 2 Napolitano M....Leonard W.J. (J. Biol. Chem. 1991)
    17. Cloning and expression of a lymphocyte activation gene (LAG-1). (PubMed id 2247088)1, 2 Baixeras E.... Triebel F. (Mol. Immunol. 1990)
    18. Two inflammatory mediator cytokine genes are closely linked and variably amplified on chromosome 17q. (PubMed id 1972563)1, 3 Irving S.G.... Kelly K. (Nucleic Acids Res. 1990)
    19. Mitogenic activation of human T cells induces two closely related genes which share structural similarities with a new family of secreted factors. (PubMed id 2521882)1, 2 Zipfel P.F.... Siebenlist U. (J. Immunol. 1989)
    20. Isolation and characterization of a cDNA encoding a putative cytokine which is induced by stimulation via the CD2 structure on human T lymphocytes. (PubMed id 2568930)1, 2 Chang H.C. and Reinherz E.L. (Eur. J. Immunol. 1989)
    21. A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast- derived inflammatory agents, growth factors, and indicators of various activation processes. (PubMed id 2521353)1, 2 Brown K.D.... Zurawski G. (J. Immunol. 1989)
    22. A novel polypeptide secreted by activated human T lymphocytes. (PubMed id 2809212)1, 2 Miller M.D.... Krangel M.S. (J. Immunol. 1989)
    23. Identification, cloning, and characterization of an immune activation gene. (PubMed id 2462251)1, 2 Lipes M.A.... Leonard W.J. (Proc. Natl. Acad. Sci. U.S.A. 1988)
    24. Macrophage inflammatory protein-1beta induced cell adhesion with increased intracellular reactive oxygen species. (PubMed id 19328808)1, 9 Tatara Y....Rakugi H. (J. Mol. Cell. Cardiol. 2009)
    25. Beta-chemokine, macrophage inflammatory protein-1beta (MIP-1beta), is highly expressed in diffuse type human gastric cancers. (PubMed id 14582706)1, 9 Saito S....Nagawa H. (amp 2003)
    26. Characterization of the role of the N-loop of MIP-1 beta in CCR5 binding. (PubMed id 12427015)1, 9 Bondue A....LiWang P.J. (Biochemistry 2002)
    27. The human MIP-1beta chemokine is encoded by two paralogous genes, ACT-2 and LAG-1. (PubMed id 11685466)1, 9 Modi W.S.... Sanford M. (Immunogenetics 2001)
    28. Interleukin-1beta induces macrophage inflammatory protein-1beta expression in human hepatocytes. (PubMed id 14746807)1, 9 Zhang T....Ho W.Z. (Cell. Immunol. 2003)
    29. Expression of macrophage inflammatory protein-1beta in human endometrium: its role in endometrial recruitment of natural killer cells. (PubMed id 12679478)1, 9 Kitaya K....Honjo H. (J. Clin. Endocrinol. Metab. 2003)
    30. Cysteinyl leukotrienes induce macrophage inflammatory protein-1 in human monocytes/macrophages. (PubMed id 18802359)1, 9 Ichiyama T....Furukawa S. (Int. Arch. Allergy Immunol. 2009)
    31. Role of osteopontin in induction of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1beta through the NF-kappaB and MAPK pathways in rheumatoid arthritis. (PubMed id 19565503)1, 9 Zheng W....Zhang J.Z. (Arthritis Rheum. 2009)
    32. Independent expression of the two paralogous CCL4 genes in monocytes and B lymphocytes. (PubMed id 14673550)1, 9 Lu J.... Sloan S.R. (Immunogenetics 2004)
    33. Reduced GRK2 level in T cells potentiates chemotaxis and signaling in response to CCL4. (PubMed id 14761932)1, 9 Vroon A....Kavelaars A. (J. Leukoc. Biol. 2004)
    34. Role for macrophage inflammatory protein (MIP)-1alpha and MIP-1beta in the development of osteolytic lesions in multiple myeloma. (PubMed id 12200385)1, 9 Abe M....Matsumoto T. (Blood 2002)
    35. Genetic subtype-independent inhibition of human immunodeficiency virus type 1 replication by CC and CXC chemokines. (PubMed id 9420238)1, 9 Trkola A....Moore J.P. (J. Virol. 1998)
    36. Identification of human macrophage inflammatory proteins 1alpha and 1beta as a native secreted heterodimer. (PubMed id 11278300)1, 9 Guan E....Norcross M.A. (J. Biol. Chem. 2001)
    37. High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation. (PubMed id 19074730)1, 9 Burger J.A....Rosenwald A. (Blood 2009)
    38. Increased serum monocyte chemoattractant protein-1, macrophage inflammatory protein-1beta, and interleukin-8 concentrations in hemophagocytic lymphohistiocytosis. (PubMed id 18623207)1, 9 Tamura K....Morikawa A. (amp 2008)
    39. Genetic variation in the CCL18-CCL3-CCL4 chemokine gene cluster influences HIV Type 1 transmission and AIDS disease progression. (PubMed id 16773571)1, 9 Modi W.S....Winkler C. (Am. J. Hum. Genet. 2006)
    40. Serum cytokine profiles in relapsing polychondritis suggest monocyte/macrophage activation. (PubMed id 15529362)1, 9 Stabler T....Kraus V.B. (Arthritis Rheum. 2004)
    41. Blockade of CC chemokine receptor 5 (CCR5)-tropic human immunodeficiency virus-1 replication in human lymphoid tissue by CC chemokines. (PubMed id 9576751)1, 9 Margolis L.B....Murphy P.M. (J. Clin. Invest. 1998)
    42. Vicious cycle between myeloma cell binding to bone marrow stromal cells via VLA-4-VCAM-1 adhesion and macrophage inflammatory protein-1alpha and MIP-1beta production. (PubMed id 19057841)1, 9 Abe M....Matsumoto T. (J. Bone Miner. Metab. 2009)
    43. Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1beta. (PubMed id 16963564)1, 9 Zhang L....LiWang P.J. (Proc. Natl. Acad. Sci. U.S.A. 2006)
    44. Identification and characterization of two genes (MIP-1beta, VE-CADHERIN) implicated in acute rejection in human heart transplantation: use of murine models in tandem with cDNA arrays. (PubMed id 15897346)1, 9 RoussouliA"res A.L....McGregor J.L. (Circulation 2005)
    45. Allosteric regulation of CCR5 by guanine nucleotides and HIV-1 envelope. (PubMed id 11485305)1, 9 Staudinger R....BandrAcs J.C. (Biochem. Biophys. Res. Commun. 2001)
    46. An arrestin-dependent multi-kinase signaling complex mediates MIP- 1beta/CCL4 signaling and chemotaxis of primary human macrophages. (PubMed id 19620252)1, 9 Cheung R....Collman R.G. (J. Leukoc. Biol. 2009)
    47. ELISpot analysis of LPS-stimulated leukocytes: human granulocytes selectively secrete IL-8, MIP-1beta and TNF-alpha. (PubMed id 19358850)1, 9 Smedman C....Paulie S. (J. Immunol. Methods 2009)
    48. Constitutive production of proinflammatory cytokines RANTES, MIP-1beta and IL-18 characterizes LGL leukemia. (PubMed id 15645140)1, 9 Kothapalli R....Loughran T.P. (Int. J. Oncol. 2005)
    49. The presence of chemokine (MCP-1, MIP-1alpha, MIP-1beta, IP-10, RANTES)-positive cells and chemokine receptor (CCR5, CXCR3)-positive cells in inflamed human gingival tissues. (PubMed id 12445801)1, 9 Kabashima H....Maeda K. (Cytokine 2002)
    50. Involvement of both the V2 and V3 regions of the CCR5-tropic human immunodeficiency virus type 1 envelope in reduced sensitivity to macrophage inflammatory protein 1alpha. (PubMed id 10644351)1, 9 Maeda Y....Harada S. (J. Virol. 2000)
    51. In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression. (PubMed id 9359702)1, 9 Scarlatti G....Lusso P. (Nat. Med. 1997)
    52. Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha. (PubMed id 8663314)1, 9 Raport C.J.... Charo I.F. (J. Biol. Chem. 1996)
    53. Human late memory CD8+ T cells have a distinct cytokine signature characterized by CC chemokine production without IL-2 production. (PubMed id 19841187)1, 9 Kim T.K....Komanduri K.V. (J. Immunol. 2009)
    54. Expansion of functionally skewed CD56-negative NK cells in chronic hepatitis C virus infection: correlation with outcome of pegylated IFN-alpha and ribavirin treatment. (PubMed id 19846870)1, 9 Gonzalez V.D....Sandberg J.K. (J. Immunol. 2009)
    55. Chemokine markers predict biochemical recurrence of prostate cancer following prostatectomy. (PubMed id 19047106)1, 9 Blum D.L....Bhowmick N.A. (Clin. Cancer Res. 2008)
    56. Antigen stimulation induces HIV envelope gp120-specific CD4(+) T cells to secrete CCR5 ligands and suppress HIV infection. (PubMed id 17765942)1, 9 Kaur G....Hioe C.E. (Virology 2007)
    57. Short communication: Influence of active tuberculosis on chemokine and chemokine receptor expression in HIV-infected persons. (PubMed id 16379602)1, 9 Hanna L.E....Swaminathan S. (AIDS Res. Hum. Retroviruses 2005)
    58. Cathepsin D specifically cleaves the chemokines macrophage inflammatory protein-1 alpha, macrophage inflammatory protein-1 beta, and SLC that are expressed in human breast cancer. (PubMed id 12651610)1, 9 Wolf M....Mazzucchelli L. (Am. J. Pathol. 2003)
    59. Differential chemokine expression profiles in human peripheral blood T lymphocytes: dependence on T-cell coreceptor and calcineurin signaling. (PubMed id 12393716)1, 9 Cristillo A.D....Bierer B.E. (Blood 2003)
    60. Marked increase in CC chemokine gene expression in both human and mouse mast cell transcriptomes following Fcepsilon receptor I cross-linking: an interspecies comparison. (PubMed id 12393595)1, 9 Nakajima T....Saito H. (Blood 2002)
    61. Induction of rapid and extensive beta-chemokine synthesis in macrophages by human immunodeficiency virus type 1 and gp120, independently of their coreceptor phenotype. (PubMed id 11602715)1, 9 Choe W....Potash M.J. (J. Virol. 2001)
    62. Induction of interactions between CD44 and hyaluronic acid by a short exposure of human T cells to diverse pro-inflammatory mediators. (PubMed id 10929056)1, 9 Ariel A....Hershkoviz R. (Immunology 2000)
    63. gp120 induces cell death in human neuroblastoma cells through the CXCR4 and CCR5 chemokine receptors. (PubMed id 10820198)1, 9 Catani M.V....Melino G. (J. Neurochem. 2000)
    64. Bacterial superantigens induce down-modulation of CC chemokine responsiveness in human monocytes via an alternative chemokine ligand-independent mechanism. (PubMed id 9973507)1, 9 Rahimpour R....Kelvin D.J. (J. Immunol. 1999)
    65. CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5. (PubMed id 8906796)1, 9 Trkola A....Moore J.P. (Nature 1996)
    66. Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES. (PubMed id 8699119)1, 9 Combadiere C.... Murphy P.M. (J. Leukoc. Biol. 1996)
    67. The chemokines IL-8, monocyte chemoattractant protein-1, and I-309 are monomers at physiologically relevant concentrations. (PubMed id 8077676)1, 9 Paolini J.F....Krangel M.S. (J. Immunol. 1994)
    68. 27-Hydroxycholesterol and 7alpha-hydroxycholesterol trigger a sequence of events leading to migration of CCR5-expressing Th1 lymphocytes. (PubMed id 24370436)1 Kim S.M....Kim K. (Toxicol. Appl. Pharmacol. 2014)
    69. Human T cell leukaemia virus type 2 tax protein mediates CC-chemokine expression in peripheral blood mononuclear cells via the nuclear factor kappa B canonical pathway. (PubMed id 24116893)1 Barrios C.S....Beilke M.A. (Clin. Exp. Immunol. 2014)
    70. Autocrine CCL3 and CCL4 induced by the oncoprotein LMP1 promote Epstein-Barr virus-triggered B cell proliferation. (PubMed id 23760235)1 Tsai S.C....Tsai C.H. (J. Virol. 2013)
    71. Dipterinyl calcium pentahydrate inhibits intracellular mycobacterial growth in human monocytes via the C-C chemokine MIP-1I^ and nitric oxide. (PubMed id 23509148)1 Sakala I.G....Hoft D.F. (Infect. Immun. 2013)
    72. The association between CCL2 polymorphisms and drug-resistant epilepsy in Chinese children. (PubMed id 23996681)1 He X....Shao J. (Epileptic Disord 2013)
    73. IL-27 enhances LPS-induced proinflammatory cytokine production via upregulation of TLR4 expression and signaling in human monocytes. (PubMed id 22156348)1 Guzzo C....Gee K. (J. Immunol. 2012)
    74. Dysregulated CC receptor/ligand in monocytes/macrophages from tongue squamous cell carcinoma patients is partially rectified by interferon I+-2b. (PubMed id 22085486)1 Chakraborty K....Baral R. (Hum. Immunol. 2012)
    75. HIV-1 proteins preferentially activate anti-inflammatory M2-type macrophages. (PubMed id 22407921)1 Chihara T....Suzu S. (J. Immunol. 2012)
    76. Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth. (PubMed id 23152559)1 Schlecker E....Cerwenka A. (J. Immunol. 2012)
    77. Adiponectin stimulates release of CCL2, -3, -4 and -5 while the surface abundance of CCR2 and -5 is simultaneously reduced in primary human monocytes. (PubMed id 21890375)1 Neumeier M....Buechler C. (Cytokine 2011)
    78. Novel peptides based on HIV-1 gp120 sequence with homology to chemokines inhibit HIV infection in cell culture. (PubMed id 21264298)1 Chertov O....Rogers T.J. (PLoS ONE 2011)
    79. Epidemic of hepatitis B with high mortality in India: association of fulminant disease with lack of CCL4 and natural killer T cells. (PubMed id 21914058)1 Tripathy A.S....Arankalle V.A. (J. Viral Hepat. 2011)
    80. LPA5 is abundantly expressed by human mast cells and important for lysophosphatidic acid induced MIP-1I^ release. (PubMed id 21464938)1 Lundequist A. and Boyce J.A. (PLoS ONE 2011)
    81. Secretion of MIP-1I^ and MIP-1I+ by CD8(+) T-lymphocytes correlates with HIV-1 inhibition independent of coreceptor usage. (PubMed id 21030011)1 Saunders K.O....Tomaras G.D. (Cell. Immunol. 2011)
    82. The expansion ability but not the quality of HIV-specific CD8(+) T cells is associated with protective human leucocyte antigen class I alleles in long-term non-progressors. (PubMed id 21978000)1 LA^pez M....Benito J.M. (Immunology 2011)
    83. Macrophage signaling in HIV-1 infection. (PubMed id 20380698)1 Herbein G....Abbas W. (Retrovirology 2010)
    84. Endothelin-1-induced macrophage inflammatory protein-1beta expression in monocytic cells involves hypoxia-inducible factor-1alpha and AP-1 and is negatively regulated by microRNA-195. (PubMed id 20952681)1 Gonsalves C. and Kalra V.K. (J. Immunol. 2010)
    85. A novel motif in HIV-1 Nef that regulates MIP-1beta chemokine release in macrophages. (PubMed id 20504918)1 Dai L. and Stevenson M. (J. Virol. 2010)
    86. CCAAT/enhancer-binding protein I^ and NF-I_B mediate high level expression of chemokine genes CCL3 and CCL4 by human chondrocytes in response to IL-1I^. (PubMed id 20702408)1 Zhang Z....Sandell L.J. (J. Biol. Chem. 2010)
    87. Nef-specific CD45RA+ CD8+ T cells secreting MIP-1beta but not IFN-gamma are associated with nonprogressive HIV-1 infection. (PubMed id 20598119)1 Dembek C.J....Cosma A. (AIDS Res Ther 2010)
    88. Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme. (PubMed id 20959807)1 Ren M....Tang W.J. (EMBO J. 2010)
    89. Replication of previous genome-wide association studies of bone mineral density in premenopausal American women. (PubMed id 20200978)1 Ichikawa S....Econs M.J. (J. Bone Miner. Res. 2010)
    90. A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-I+ and MIP1-I^, a lack of IL-17, and a Th1-bias in males. (PubMed id 21082024)1 Snyder-Cappione J.E....Nixon D.F. (PLoS ONE 2010)
    91. beta-Chemokine production by neural and glial progenitor cells is enhanced by HIV-1 Tat: effects on microglial migration. (PubMed id 20403075)1 Hahn Y.K....Knapp P.E. (J. Neurochem. 2010)
    92. HIV-1 infection inhibits cytokine production in human thymic macrophages. (PubMed id 20817073)1 Rozmyslowicz T....Gaulton G.N. (Exp. Hematol. 2010)
    93. CCL4/MIP-1beta levels in tear fluid and serum of patients with cystic fibrosis. (PubMed id 20575639)1 Mrugacz M. (amp 2010)
    94. Activation of p38 MAPK is required in monocytic and neuronal cells for HIV glycoprotein 120-induced neurotoxicity. (PubMed id 20855878)1 Medders K.E....Kaul M. (J. Immunol. 2010)
    95. Exploration of disease mechanism in acute kidney injury using a multiplex bead array assay: a nested case-control pilot study. (PubMed id 20482449)1 Liangos O....Jaber B.L. (Biomarkers 2010)
    96. CCR5 ligands modulate CXCL12-induced chemotaxis, adhesion, and Akt phosphorylation of human cord blood CD34+ cells. (PubMed id 19917679)1 Basu S. and Broxmeyer H.E. (J. Immunol. 2009)
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    225. Inhibition of HIV type 1 BaL replication by MIP-1alpha, MIP-1beta, and RANTES in macrophages. (PubMed id 9491913)9 Capobianchi M.R....Dianzani F. (AIDS Res. Hum. Retroviruses 1998)
    226. Clustering of cytokine genes on mouse chromosome 11. (PubMed id 1969921)9 Wilson S.D....Dorf M.E. (J. Exp. Med. 1990)
    227. Diagnostic utility of cytokine biomarkers in the evaluation of acute knee pain. (PubMed id 19797564)9 Cuellar J.M....Yeomans D.C. (J Bone Joint Surg Am 2009)
    228. Expression of mRNA for chemokines and chemokine receptors in tissues of the myometrium and uterine leiomyoma. (PubMed id 19024011)9 Syssoev K.A....Totolian A.A. (Bull. Exp. Biol. Med. 2008)
    229. Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity. (PubMed id 18578883)9 Bozza F.A....Kubelka C.F. (BMC Infect. Dis. 2008)
    230. Intrathecal upregulation of IFN-gamma and MIP-1beta in juvenile muscular atrophy of the distal upper extremity. (PubMed id 18723190)9 Tanaka M....Kira J. (J. Neurol. Sci. 2008)
    231. Multiplex bead analysis of vitreous and serum concentrations of inflammatory and proangiogenic factors in diabetic patients. (PubMed id 18385799)9 Maier R....Haas A. (Mol. Vis. 2008)
    232. Expression of immunomodulatory genes in human monocytes induced by voriconazole in the presence of Aspergillus fumigatus. (PubMed id 17178797)9 Simitsopoulou M....Walsh T.J. (Antimicrob. Agents Chemother. 2007)
    233. CC and CXC chemokines in breastmilk are associated with mother-to-child HIV-1 transmission. (PubMed id 16250882)9 Farquhar C....John-Stewart G.C. (Curr. HIV Res. 2005)
    234. Differential expression of cytokines and chemokines in human monocytes induced by lipid formulations of amphotericin B. (PubMed id 15793118)9 Simitsopoulou M....Walsh T.J. (Antimicrob. Agents Chemother. 2005)
    235. Expression of the beta chemokines CCL3, CCL4, CCL5 and their receptors in idiopathic inflammatory myopathies. (PubMed id 15634233)9 Civatte M....Figarella-Branger D. (Neuropathol. Appl. Neurobiol. 2005)
    236. Gene expression profile analysis in human T lymphocytes from patients with Down Syndrome. (PubMed id 15598213)9 Giannone S....Zannotti M. (Ann. Hum. Genet. 2004)
    237. Prostaglandin E2 inhibits production of the inflammatory chemokines CCL3 and CCL4 in dendritic cells. (PubMed id 12960284)9 Jing H....Ganea D. (J. Leukoc. Biol. 2003)
    238. Serum levels of chemokines correlate with disease activity in patients with retinal vasculitis. (PubMed id 14611909)9 Wallace G.R....Stanford M.R. (Immunol. Lett. 2003)
    239. Altered intracellular expression of the chemokines MIP-1alpha, MIP-1beta and IL-8 by peripheral blood CD4+ and CD8+ T cells in mild allergic asthma. (PubMed id 12653799)9 Grob M....Bisset L.R. (Allergy 2003)
    240. Impact of NNRTI compared to PI-based highly active antiretroviral therapy on CCR5 receptor expression, beta-chemokines and IL-16 secretion in HIV-1 infection. (PubMed id 12390317)9 Burton C.T....Imami N. (Clin. Exp. Immunol. 2002)
    241. Autocrine role of macrophage inflammatory protein-1 beta in human T-cell lymphotropic virus type-I tax-transfected Jurkat T-cells. (PubMed id 11573951)9 Sharma V. and Lorey S.L. (Biochem. Biophys. Res. Commun. 2001)
    242. Ligation of CD11b and CD11c beta(2) integrins by antibodies or soluble CD23 induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta production in primary human monocytes through a pathway dependent on nuclear factor-kappaB. (PubMed id 11342414)9 Rezzonico R....Dayer J.M. (Blood 2001)
    243. The seventh transmembrane domain of cc chemokine receptor 5 is critical for MIP-1beta binding and receptor activation: role of MET 287. (PubMed id 11237703)9 Youn B.S....Kwon B.S. (Biochem. Biophys. Res. Commun. 2001)
    244. Cryptococcus neoformans induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta in human microglia: role of specific antibody and soluble capsular polysaccharide. (PubMed id 11179358)9 Goldman D....Lee S.C. (Infect. Immun. 2001)
    245. HIV-1 glycoprotein 120 induces the MMP-9 cytopathogenic factor production that is abolished by inhibition of the p38 mitogen-activated protein kinase signaling pathway. (PubMed id 11468147)9 MissAc D....Veas F. (Blood 2001)
    246. Examination of the function of RANTES, MIP-1alpha, and MIP-1beta following interaction with heparin-like glycosaminoglycans. (PubMed id 10766793)9 Ali S....Kirby J.A. (J. Biol. Chem. 2000)
    247. Beta-chemokine receptor CCR5 signals through SHP1, SHP2, and Syk. (PubMed id 10747947)9 Ganju R.K....Groopman J.E. (J. Biol. Chem. 2000)
    248. Macrophage inflammatory protein-1alpha (MIP-1alpha), MIP-1beta, and RANTES mRNA semiquantification and protein expression in active demyelinating multiple sclerosis (MS) lesions. (PubMed id 11091283)9 Boven L.A....De Groot C.J. (Clin. Exp. Immunol. 2000)
    249. Human vascular smooth muscle cells possess functional CCR5. (PubMed id 10681524)9 Schecter A.D....Taubman M.B. (J. Biol. Chem. 2000)
    250. Cocaine differentially modulates chemokine production by mononuclear cells from normal donors and human immunodeficiency virus type 1-infected patients. (PubMed id 10618285)9 Nair M.P....Schwartz S.A. (Clin. Diagn. Lab. Immunol. 2000)
    251. Expression of C-C chemokines in bronchoalveolar lavage cells from patients with granulomatous lung diseases. (PubMed id 10384061)9 Oshima M....Yamakido M. (Lung 1999)
    252. CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist. (PubMed id 10477718)9 Blanpain C....Parmentier M. (Blood 1999)
    253. Augmented production of chemokines (monocyte chemotactic protein-1 (MCP-1), macrophage inflammatory protein-1alpha (MIP-1alpha) and MIP-1beta) in patients with systemic sclerosis: MCP-1 and MIP-1alpha may be involved in the development of pulmonary fibrosis. (PubMed id 10403930)9 Hasegawa M....Takehara K. (Clin. Exp. Immunol. 1999)
    254. Molecular cloning of feline CC-chemokine cDNAs. (PubMed id 9839867)9 Endo Y....Hasegawa A. (Vet. Immunol. Immunopathol. 1998)
    255. Expression of macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES genes in lymph nodes from HIV+ individuals: correlation with a Th1-type cytokine response. (PubMed id 9566795)9 Trumpfheller C....Frosch S. (Clin. Exp. Immunol. 1998)
    256. Human astrocytoma cells are capable of producing macrophage inflammatory protein-1beta. (PubMed id 9525834)9 Ishii N....Abe H. (J. Neurooncol. 1998)
    257. Synthesis of the CC-chemokines MIP-1alpha, MIP-1beta, and RANTES is associated with a type 1 immune response. (PubMed id 8871660)9 Schrum S....Zipfel P.F. (J. Immunol. 1996)
    258. Plasma cells induce apoptosis of pre-B cells by interacting with bone marrow stromal cells. (PubMed id 8605355)9 Tsujimoto T....Kawano M.M. (Blood 1996)
    259. Serum chemokine levels in major depressive disorder. (PubMed id 19592174)9 Lehto S.M....Hintikka J. (Psychoneuroendocrinology 2010)
    260. Alteration of TLR3 pathways by glucocorticoids may be responsible for immunosusceptibility of human corneal epithelial cells to viral infections. (PubMed id 19452017)9 Hara Y....Ohashi Y. (Mol. Vis. 2009)
    261. Effects of oral and transdermal estrogen therapies on circulating cytokines and chemokines in postmenopausal women with hysterectomy. (PubMed id 19451213)9 Yasui T....Irahara M. (Eur. J. Endocrinol. 2009)
    262. Chemokines are secreted by monocytes following OK-432 (lyophilized Streptococcus pyogenes) stimulation. (PubMed id 19175917)9 Olsnes C....Aarstad H.J. (BMC Immunol. 2009)
    263. Expression of cytokine signaling genes in morbidly obese patients with non-alcoholic steatohepatitis and hepatic fibrosis. (PubMed id 19280268)9 Estep J.M....Younossi Z.M. (Obes Surg 2009)
    264. Serial changes of cytokines in active ulcerative colitis: effects of antibiotic combination therapy. (PubMed id 19760932)9 Sato K....Ohkusa T. (Hepatogastroenterology 2009)
    265. Sequential changes in serum cytokines reflect viral RNA kinetics in target organs of a coxsackievirus B infection in mice. (PubMed id 19430896)9 Lundgren M....IlbAock N.G. (J. Clin. Immunol. 2009)
    266. Fat-storing multilocular cells expressing CCR5 increase in the thymus with advancing age: potential role for CCR5 ligands on the differentiation and migration of preadipocytes. (PubMed id 20046229)9 Mello Coelho V.d....Taub D.D. (Int J Med Sci 2009)
    267. Co-cultures of multiple cell types mimic pulmonary cell communication in response to urban PM10. (PubMed id 18653652)9 Alfaro-Moreno E....Hoet P.H. (Eur. Respir. J. 2008)
    268. CD40 activation in human pancreatic islets and ductal cells. (PubMed id 18661119)9 Klein D....Pastori R.L. (Diabetologia 2008)
    269. Effect of CCR5 receptor antagonists on endocytosis of the human CCR5 receptor in CHO-K1 cells. (PubMed id 18223665)9 Longden J....Hill S.J. (Br. J. Pharmacol. 2008)
    270. Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical status. (PubMed id 18974782)9 Critchfield J.W....Shacklett B.L. (PLoS ONE 2008)
    271. Reduction of chemokine secretion in response to mycobacteria in infliximab-treated patients. (PubMed id 18160618)9 Newton S.M....Pasvol G. (Clin. Vaccine Immunol. 2008)
    272. Clinical importance of bronchoalveolar lavage fluid and blood cytokines, surfactant protein D, and Kerbs von Lungren 6 antigen in idiopathic pulmonary alveolar proteinosis. (PubMed id 19046553)9 Lin F.C....Chang S.C. (Mayo Clin. Proc. 2008)
    273. No major differences in the functional profile of HIV Gag and Nef-specific CD8+ responses between long-term nonprogressors and typical progressors. (PubMed id 18729773)9 LA^pez M....Benito J.M. (AIDS Res. Hum. Retroviruses 2008)
    274. Anti-proinflammatory effects of sirolimus on human islet preparations. (PubMed id 18622277)9 Mita A....Ichii H. (Transplantation 2008)
    275. Glycated human serum albumin enhances macrophage inflammatory protein-1beta mRNA expression through protein kinase C-delta and NADPH oxidase in macrophage-like differentiated U937 cells. (PubMed id 18155175)9 Higai K....Matsumoto K. (Biochim. Biophys. Acta 2008)
    276. Exuberant expression of chemokine genes by adult human articular chondrocytes in response to IL-1beta. (PubMed id 18565769)9 Sandell L.J....Patra D. (Osteoarthr. Cartil. 2008)
    277. Changes in extracellular concentrations of some cytokines, chemokines, and neurotrophic factors after insertion of intracerebral microdialysis catheters in neurosurgical patients. (PubMed id 18300902)9 MellergAYrd P....Hillman J. (Neurosurgery 2008)
    278. Biomarker profile in off-pump and on-pump coronary artery bypass grafting surgery in low-risk patients. (PubMed id 18498809)9 Castellheim A....Mollnes T.E. (Ann. Thorac. Surg. 2008)
    279. Phenotypic dichotomies in the foreign body reaction. (PubMed id 17706278)9 Anderson J.M. and Jones J.A. (Biomaterials 2007)
    280. LPS induces secretion of chemokines by human syncytiotrophoblast cells in a MAPK-dependent manner. (PubMed id 16870263)9 Lucchi N.W. and Moore J.M. (J. Reprod. Immunol. 2007)
    281. Immunopathogenesis of respiratory syncytial virus bronchiolitis. (PubMed id 17436234)9 Bennett B.L....Piedra P.A. (J. Infect. Dis. 2007)
    282. High production of RANTES and MIP-1alpha in the tropical spastic paraparesis/HTLV-1-associated myelopathy (TSP/HAM). (PubMed id 17588676)9 Montanheiro P....Casseb J. (J. Neuroimmunol. 2007)
    283. Impaired renal function and duration of dialysis therapy are associated with oxidative stress and proatherogenic cytokine levels in patients with end-stage renal disease. (PubMed id 17046733)9 Pawlak K....Mysliwiec M. (Clin. Biochem. 2007)
    284. Low-intensity pulsed ultrasound (LIPUS) induces RANKL, MCP-1, and MIP-1beta expression in osteoblasts through the angiotensin II type 1 receptor. (PubMed id 17167786)9 Bandow K....Matsuguchi T. (J. Cell. Physiol. 2007)
    285. The chemokines, CX3CL1, CCL14, and CCL4, promote human trophoblast migration at the feto-maternal interface. (PubMed id 16452465)9 Hannan N.J....Salamonsen L.A. (Biol. Reprod. 2006)
    286. Vitreous Chemokines and Sho (Zheng in Chinese) of Chinese-Korean-Japanese medicine in patients with diabetic vitreoretinopathy. (PubMed id 16883625)9 Hayasaka S....Shimada Y. (Am. J. Chin. Med. 2006)
    287. Multiplexed flow cytometric analyses of pro- and anti-inflammatory cytokines in the culture media of oxysterol-treated human monocytic cells and in the sera of atherosclerotic patients. (PubMed id 16604541)9 Prunet C....Lizard G. (Cytometry A 2006)
    288. CD40-CD40 ligand interaction activates proinflammatory pathways in pancreatic islets. (PubMed id 16936191)9 BarbAc-Tuana F.M....Pastori R.L. (Diabetes 2006)
    289. Long-term erythropoietin therapy decreases CC-chemokine levels and intima-media thickness in hemodialyzed patients. (PubMed id 17119331)9 Pawlak K....Mysliwiec M. (Am. J. Nephrol. 2006)
    290. Molecular mechanisms for the release of chemokines from human leukemic mast cell line (HMC)-1 cells activated by SCF and TNF-alpha: roles of ERK, p38 MAPK, and NF-kappaB. (PubMed id 16436136)9 Wong C.K....Lam C.W. (Allergy 2006)
    291. Increased expression and secretion of interleukin-6 in human parvovirus B19 non-structural protein (NS1) transfected COS-7 epithelial cells. (PubMed id 16542377)9 Hsu T.C....Tsay G.J. (Clin. Exp. Immunol. 2006)
    292. Inflammation but not oxidative stress is associated with beta-chemokine levels and prevalence of cardiovascular disease in uraemic patients. (PubMed id 17070067)9 Pawlak K....MyA9liwiec M. (Cytokine 2006)
    293. Intestinal neuro-epithelial interactions modulate neuronal chemokines production. (PubMed id 16620783)9 Tixier E....Neunlist M. (Biochem. Biophys. Res. Commun. 2006)
    294. Toll-like receptor (TLR) 2-9 agonists-induced cytokines and chemokines: I. Comparison with T cell receptor-induced responses. (PubMed id 17250816)9 Ghosh T.K....Alkan S.S. (Cell. Immunol. 2006)
    295. Multiplex bead array assay for detection of 25 soluble cytokines in blister fluid of patients with complex regional pain syndrome type 1. (PubMed id 16864900)9 Heijmans-Antonissen C....Zijlstra F.J. (Mediators Inflamm. 2006)
    296. Chemokine expression in the monocytic cell line THP-1 in response to purified shiga toxin 1 and/or lipopolysaccharides. (PubMed id 15618178)9 Harrison L.M....Tesh V.L. (Infect. Immun. 2005)
    297. Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment. (PubMed id 16053532)9 Ishii H....van Eeden S.F. (Respir. Res. 2005)
    298. Cytokines and fibrinolytic enzymes in tuberculous and parapneumonic effusions. (PubMed id 15897010)9 Lin F.C....Chang S.C. (Clin. Immunol. 2005)
    299. Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis. (PubMed id 15743872)9 Ishizu T....Kira J. (Brain 2005)
    300. Muscle damage is linked to cytokine changes following a 160-km race. (PubMed id 16061149)9 Nieman D.C....Lind R.H. (Brain Behav. Immun. 2005)
    301. Circulating beta-chemokines and matrix metalloproteinase-9/tissue inhibitor of metalloproteinase-1 system in hemodialyzed patients--role of oxidative stress. (PubMed id 15896974)9 Pawlak K....Mysliwiec M. (Cytokine 2005)
    302. Investigation of CC and CXC chemokine quaternary state mutants. (PubMed id 16256937)9 Jin H....LiWang P.J. (Biochem. Biophys. Res. Commun. 2005)
    303. Kinetic analysis of cytokine response to cigarette smoke condensate by human endothelial and monocytic cells. (PubMed id 15885868)9 Nordskog B.K....Hellmann G.M. (Toxicology 2005)
    304. Impact of the placental cytokine-chemokine balance on regulation of cell-cell contact-induced human immunodeficiency virus type 1 translocation across a trophoblastic barrier in vitro. (PubMed id 16160157)9 Derrien M....Menu E. (J. Virol. 2005)
    305. Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5-mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor. (PubMed id 15569263)9 Giri R.K....Kalra V.K. (J. Neurochem. 2004)
    306. Semiquantitative analysis of intrahepatic CC-chemokine mRNas in chronic hepatitis C. (PubMed id 15770052)9 Nischalke H.D....Dumoulin F.L. (Mediators Inflamm. 2004)
    307. Selective induction of Th2-attracting chemokines CCL17 and CCL22 in human B cells by latent membrane protein 1 of Epstein-Barr virus. (PubMed id 14747532)9 Nakayama T....Yoshie O. (J. Virol. 2004)
    308. Induction of alpha and beta chemokines by intestinal epithelial cells stimulated with Campylobacter jejuni. (PubMed id 15001302)9 Bakhiet M....Botta G.A. (J. Infect. 2004)
    309. Recall antigen activation induces prompt release of CCR5 ligands from PBMC: implication in memory responses and immunization. (PubMed id 15466454)9 Sun L....Garzino-Demo A. (Int. Immunol. 2004)
    310. Induction of various immune modulatory molecules in CD34(+) hematopoietic cells. (PubMed id 14742640)9 Umland O....Ulmer A.J. (J. Leukoc. Biol. 2004)
    311. Chemokine mRNA levels in mononucleated cells of HIV-infected patients before and after initiation of PI- versus NNRTI-containing HAART. (PubMed id 15168802)9 Wasmuth J.C....Dumoulin F.L. (Antiviral Res. 2004)
    312. Desialylation of glycoconjugates on the surface of monocytes activates the extracellular signal-related kinases ERK 1/2 and results in enhanced production of specific cytokines. (PubMed id 14634064)9 Stamatos N.M....Cross A.S. (J. Leukoc. Biol. 2004)
    313. A new pharmacological effect of salicylates: inhibition of NFAT-dependent transcription. (PubMed id 15494524)9 Aceves M....GarcA-a-RodrA-guez C. (J. Immunol. 2004)
    314. The effects of pre-B-cell colony-enhancing factor on the human fetal membranes by microarray analysis. (PubMed id 14586377)9 Ognjanovic S....Bryant-Greenwood G.D. (Am. J. Obstet. Gynecol. 2003)
    315. Helicobacter pylori water soluble surface proteins prime human neutrophils for enhanced production of reactive oxygen species and stimulate chemokine production. (PubMed id 12719454)9 Shimoyama T....Sugawara K. (J. Clin. Pathol. 2003)
    316. The relative activity of CXCR3 and CCR5 ligands in T lymphocyte migration: concordant and disparate activities in vitro and in vivo. (PubMed id 12960247)9 Stanford M.M. and Issekutz T.B. (J. Leukoc. Biol. 2003)
    317. Early up-regulation of chemokine expression in fulminant hepatic failure. (PubMed id 12579535)9 Leifeld L....Spengler U. (J. Pathol. 2003)
    318. Macrophages and lymphocytes differentially modulate the ability of RANTES to inhibit HIV-1 infection. (PubMed id 12960233)9 Gross E....Schmidtmayerova H. (J. Leukoc. Biol. 2003)
    319. CC-chemokine activation in acute pancreatitis: enhanced release of monocyte chemoattractant protein-1 in patients with local and systemic complications. (PubMed id 12589535)9 Rau B....Beger H.G. (Intensive Care Med 2003)
    320. Evidence for CD4-enchanced signaling through the chemokine receptor CCR5. (PubMed id 12531905)9 Staudinger R....Zolla-Pazner S. (J. Biol. Chem. 2003)
    321. Heterologous desensitization of T cell functions by CCR5 and CXCR4 ligands: inhibition of cellular signaling, adhesion and chemotaxis. (PubMed id 12502723)9 Hecht I....Lider O. (Int. Immunol. 2003)
    322. Proinflammatory cytokines induce NF-kappaB-dependent/NO-independent chemokine gene expression in MIN6 beta cells. (PubMed id 12697414)9 Baker M.S....Kaufman D.B. (J. Surg. Res. 2003)
    323. Relative importance of CCR5 and antineutrophil cytoplasmic antibodies in patients with Wegener's granulomatosis. (PubMed id 12858455)9 Zhou Y....Hoffman G.S. (J. Rheumatol. 2003)
    324. An anti-inflammatory oligopeptide produced by Entamoeba histolytica down-regulates the expression of pro-inflammatory chemokines. (PubMed id 15157024)9 Utrera-Barillas D....Kretschmer R.R. (Parasite Immunol. 2003)
    325. Antiinflammatory effect of retrovirally transfected interleukin-10 on monosodium urate monohydrate crystal-induced acute inflammation in murine air pouches. (PubMed id 12355499)9 Murakami Y....Kitasato H. (Arthritis Rheum. 2002)
    326. Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors. (PubMed id 11932423)9 Zaiss A.K....Muruve D.A. (J. Virol. 2002)
    327. The increased expression of an array of C-X-C and C-C chemokines in the colonic mucosa of patients with ulcerative colitis: regulation by corticosteroids. (PubMed id 11808935)9 Yang S.K....Min Y.I. (Am. J. Gastroenterol. 2002)
    328. Chemokine activation within 24 hours after blunt accident trauma. (PubMed id 11900333)9 Liener U.C....Gebhard F. (Shock 2002)
    329. Inflammatory responses in Ebola virus-infected patients. (PubMed id 11982604)9 Baize S....Mavoungou E. (Clin. Exp. Immunol. 2002)
    330. RANTES expression is a predictor of survival in stage I lung adenocarcinoma. (PubMed id 12473593)9 Moran C.J....Beer D.G. (Clin. Cancer Res. 2002)
    331. CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor. (PubMed id 12239139)9 Honczarenko M....Silberstein L.E. (Blood 2002)
    332. Stimulation and inhibition of uveal melanoma invasion by HGF, GRO, IL-1alpha and TGF-beta. (PubMed id 12356817)9 Woodward J.K....Sisley K. (amp 2002)
    333. Glomerular chemokine expression and the effect of steroid and cyclophosphamide pulse therapy in human crescentic glomerulonephritis. (PubMed id 12411099)9 Chen S....Li L. (Chin. Med. J. 2002)
    334. Mycobacterium avium complex promotes recruitment of monocyte hosts for HIV-1 and bacteria. (PubMed id 12244182)9 Hale-Donze H....Wahl S.M. (J. Immunol. 2002)
    335. Numerous growth factors, cytokines, and chemokines are secreted by human CD34(+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner. (PubMed id 11342433)9 Majka M....Ratajczak M.Z. (Blood 2001)
    336. beta1 Integrin-extracellular matrix protein interaction modulates the migratory response to chemokine stimulation. (PubMed id 11527209)9 Shenoy P.S....Chan B.M. (Biochem. Cell Biol. 2001)
    337. Expression of cytokine and chemokine genes by human middle ear epithelial cells induced by formalin-killed Haemophilus influenzae or its lipooligosaccharide htrB and rfaD mutants. (PubMed id 11349030)9 Tong H.H....DeMaria T.F. (Infect. Immun. 2001)
    338. CC chemokines and the receptors CCR3 and CCR5 are differentially expressed in the nonneoplastic leukocytic infiltrates of Hodgkin disease. (PubMed id 11238088)9 Buri C....Mazzucchelli L. (Blood 2001)
    339. Systemic cytokine response in children bitten by snakes in Costa Rica. (PubMed id 11753186)9 Avila-AgA1ero M.L....Faingezicht I. (Pediatr Emerg Care 2001)
    340. Multiplex analysis of cytokines in the blood of cynomolgus macaques naturally infected with Ebola virus (Reston serotype). (PubMed id 11596094)9 Hutchinson K.L....Rollin P.E. (J. Med. Virol. 2001)
    341. Human peripheral blood T cells, monocytes, and macrophages secrete macrophage inflammatory proteins 1alpha and 1beta following stimulation with heat-inactivated Brucella abortus. (PubMed id 11349047)9 Zaitseva M....Golding B. (Infect. Immun. 2001)
    342. In vivo modulation of the allogeneic immune response by human fetal kidneys: the role of cytokines, chemokines, and cytolytic effector molecules. (PubMed id 10798773)9 Dekel B....Reisner Y. (Transplantation 2000)
    343. Elevated chemokine levels in bronchoalveolar lavage fluid of patients with eosinophilic pneumonia. (PubMed id 11031344)9 Katoh S....Matsukura S. (J. Allergy Clin. Immunol. 2000)
    344. Influenza A and sendai viruses induce differential chemokine gene expression and transcription factor activation in human macrophages. (PubMed id 11022002)9 Matikainen S....Julkunen I. (Virology 2000)
    345. Increases in intrahepatic CD68 positive cells, MAC387 positive cells, and proinflammatory cytokines (particularly interleukin 18) in chronic hepatitis C infection. (PubMed id 10644323)9 McGuinness P.H....McCaughan G.W. (Gut 2000)
    346. Stimulation of macrophage inflammatory protein-1alpha, macrophage inflammatory protein-1beta, and RANTES by Candida albicans and Cryptococcus neoformans in peripheral blood mononuclear cells from persons with and without human immunodeficiency virus infection. (PubMed id 10669379)9 Huang C. and Levitz S.M. (J. Infect. Dis. 2000)
    347. Circulating levels and ex vivo production of beta-chemokines, interferon gamma, and interleukin 2 in advanced human immunodeficiency virus type 1 infection: the effect of protease inhibitor therapy. (PubMed id 10875609)9 De Luca A....Antinori A. (AIDS Res. Hum. Retroviruses 2000)
    348. Activation of C-C beta-chemokines in human peripheral blood gammadelta T cells by isopentenyl pyrophosphate and regulation by cytokines. (PubMed id 10607682)9 Cipriani B....Brosnan C.F. (Blood 2000)
    349. Differential induction of chemokines in human microglia by type I and II interferons. (PubMed id 10642753)9 McManus C.M....Lee S.C. (Glia 2000)
    350. In vitro studies on the trafficking of dendritic cells through endothelial cells and extra-cellular matrix. (PubMed id 11097208)9 Bianchi G....Allavena P. (Dev. Immunol. 2000)
    351. Endogenous levels of C-C chemokines MIP-1alpha, MIP-1beta, and RANTES do not reflect the disease course in HIV-seropositive individuals. (PubMed id 11289705)9 Kreuzer K.A....Spengler U. (amp 2000)
    352. Higher macrophage inflammatory protein (MIP)-1alpha and MIP-1beta levels from CD8+ T cells are associated with asymptomatic HIV-1 infection. (PubMed id 11095721)9 Cocchi F....Gallo R.C. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    353. The limited infectability by R5 HIV of CD34(+) cells from thymus, cord, and peripheral blood and bone marrow is explained by their ability to produce beta-chemokines. (PubMed id 11146155)9 Majka M....Ratajczak M.Z. (Exp. Hematol. 2000)
    354. C-C chemokine profile of cord blood mononuclear cells: selective defect in RANTES production. (PubMed id 10627485)9 Hariharan D....Douglas S.D. (Blood 2000)
    355. Inhibition of human immunodeficiency virus type 1 replication prior to reverse transcription by influenza virus stimulation. (PubMed id 10775586)9 Pinto L.A....Shearer G.M. (J. Virol. 2000)
    356. CXCR4 and CCR5 expression by H9 T-cells is downregulated by a peptide-nucleic acid immunomodulator. (PubMed id 11064099)9 Lazzarino D.A....Alexander R.J. (Immunol. Lett. 2000)
    357. Amphotericin B induces expression of genes encoding chemokines and cell adhesion molecules in the human monocytic cell line THP-1. (PubMed id 10979935)9 Rogers P.D....Cleary J.D. (J. Infect. Dis. 2000)
    358. Limited expression of R5-tropic HIV-1 in CCR5-positive type 1-polarized T cells explained by their ability to produce RANTES, MIP-1alpha, and MIP-1beta. (PubMed id 10666186)9 Annunziato F....Romagnani S. (Blood 2000)
    359. Defective chemokine production in T-leukemia cell lines and its possible functional role. (PubMed id 11097202)9 Ivanoff J....Sundqvist K.G. (Dev. Immunol. 2000)
    360. Role of MIP-1beta and RANTES in HIV-1 infection of microglia: inhibition of infection and induction by IFNbeta. (PubMed id 11024554)9 Kitai R....Lee S.C. (J. Neuroimmunol. 2000)
    361. Differential regulation of CC chemokine gene expression in human immunodeficiency virus-infected myeloid cells. (PubMed id 10497106)9 GAcnin P....Hiscott J. (Virology 1999)
    362. Longitudinal analysis of serum chemokine levels in the course of HIV-1 infection. (PubMed id 10197372)9 Polo S....Lusso P. (AIDS 1999)
    363. Sensitivity of human immunodeficiency virus infection to various alpha, beta and gamma chemokines. (PubMed id 10501489)9 Greco G....Levy J.A. (J. Gen. Virol. 1999)
    364. CCR5 and CXCR4 chemokine receptor expression and beta-chemokine production during early T cell repopulation induced by highly active anti-retroviral therapy. (PubMed id 10540164)9 Giovannetti A....Aiuti F. (Clin. Exp. Immunol. 1999)
    365. Chemokine modulation of matrix metalloproteinase and TIMP production in adult rat brain microglia and a human microglial cell line in vitro. (PubMed id 10559777)9 Cross A.K. and Woodroofe M.N. (Glia 1999)
    366. Chemokines induce the cellular migration of MCF-7 human breast carcinoma cells: subpopulations of tumour cells display positive and negative chemotaxis and differential in vivo growth potentials. (PubMed id 10651305)9 Prest S.J....Ali S.A. (amp 1999)
    367. Elevated chemokine concentrations in sera of human immunodeficiency virus (HIV)-seropositive and HIV-seronegative patients with tuberculosis: a possible role for mycobacterial lipoarabinomannan. (PubMed id 10417209)9 Juffermans N.P....van der Poll T. (Infect. Immun. 1999)
    368. Proinflammatory cytokines and chemokine production and expression by human osteoblasts isolated from patients with rheumatoid arthritis and osteoarthritis. (PubMed id 10229398)9 Lisignoli G....Facchini A. (J. Rheumatol. 1999)
    369. Flow cytometric analysis of intracellular chemokines in chondrocytes in vivo: constitutive expression and enhancement in osteoarthritis and rheumatoid arthritis. (PubMed id 10437780)9 Borzi R.M....Facchini A. (FEBS Lett. 1999)
    370. Expression and function of CXC and CC chemokines in human malignant liver tumors: a role for human monokine induced by gamma-interferon in lymphocyte recruitment to hepatocellular carcinoma. (PubMed id 10385645)9 Yoong K.F....Adams D.H. (Hepatology 1999)
    371. Circulating levels of beta-chemokines in systemic lupus erythematosus. (PubMed id 10090164)9 Kaneko H....Hashimoto H. (J. Rheumatol. 1999)
    372. Chemokine gene expression in human oral mucosa. (PubMed id 10467937)9 Zehnder M....Bickel M. (Eur. J. Oral Sci. 1999)
    373. Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein. (PubMed id 10574939)9 Blanpain C....Parmentier M. (J. Biol. Chem. 1999)
    374. Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP- 1beta, and RANTES. Characterization of active disaggregated chemokine variants. (PubMed id 10347159)9 Czaplewski L.G.... Hunter M.G. (J. Biol. Chem. 1999)
    375. Localization of C-X-C and C-C chemokines to renal tubular epithelial cells in human kidney transplants is not confined to acute cellular rejection. (PubMed id 10342733)9 Sibbring J.S....Christmas S.E. (Transpl. Immunol. 1998)
    376. Chemokine expression and leucocyte infiltration in SjAPgren's syndrome. (PubMed id 9714357)9 Cuello C....Wakefield D. (Br. J. Rheumatol. 1998)
    377. Immunocytochemical detection of cytokines and chemokines in Langerhans cells and in vitro derived dendritic cells. (PubMed id 9692862)9 LorAc K....Andersson J. (J. Immunol. Methods 1998)
    378. Regulated production of type I collagen and inflammatory cytokines by peripheral blood fibrocytes. (PubMed id 9551999)9 Chesney J....Bucala R. (J. Immunol. 1998)
    379. Dynamic regulation of alpha- and beta-chemokine expression in the central nervous system during mouse hepatitis virus-induced demyelinating disease. (PubMed id 9551936)9 Lane T.E....Buchmeier M.J. (J. Immunol. 1998)
    380. Concentrations of circulating beta-chemokines do not correlate with viral load in human immunodeficiency virus-infected individuals. (PubMed id 9665956)9 Kakkanaiah V.N....Peter J.B. (Clin. Diagn. Lab. Immunol. 1998)
    381. Erratum to &quot;Immunocytochemical detection of cytokines and chemokines in Langerhans cells and in vitro derived dendritic cells&quot;. (PubMed id 9819134)9 LorAc K....Andersson J. (J. Immunol. Methods 1998)
    382. Delta9 tetrahydrocannabinol and cannabidiol alter cytokine production by human immune cells. (PubMed id 9858061)9 Srivastava M.D....Brouhard B. (Immunopharmacology 1998)
    383. Transendothelial chemotaxis of human alpha/beta and gamma/delta T lymphocytes to chemokines. (PubMed id 9485190)9 Roth S.J....Springer T.A. (Eur. J. Immunol. 1998)
    384. Cervical human immunodeficiency virus type 1 shedding is associated with genital beta-chemokine secretion. (PubMed id 9780253)9 Iversen A.K....Skinhoj P. (J. Infect. Dis. 1998)
    385. Induction of beta-family chemokines mRNA in human embryonic astrocytes by inflammatory cytokines and measles virus protein. (PubMed id 10405024)9 Xiao B.G....Link H. (J. Neurocytol. 1998)
    386. In vivo production of cytokines and beta (C-C) chemokines in human recurrent herpes simplex lesions--do herpes simplex virus-infected keratinocytes contribute to their production? (PubMed id 9534953)9 Mikloska Z....Cunningham A.L. (J. Infect. Dis. 1998)
    387. Inhibition of simian immunodeficiency virus (SIV) replication by CD8(+) T lymphocytes from macaques immunized with live attenuated SIV. (PubMed id 9658070)9 Gauduin M.C....Johnson R.P. (J. Virol. 1998)
    388. Beta-chemokine expression and distribution in paraffin-embedded transplant renal biopsy sections: analysis by scanning laser confocal microscopy. (PubMed id 9720994)9 Robertson H....Kirby J.A. (Histochem. Cell Biol. 1998)
    389. Primary CD8+ cells from HIV-infected individuals can suppress productive infection of macrophages independent of beta-chemokines. (PubMed id 9465084)9 Barker E....Levy J.A. (Proc. Natl. Acad. Sci. U.S.A. 1998)
    390. Evidence for RANTES, monocyte chemotactic protein-1, and macrophage inflammatory protein-1 beta expression in Kawasaki disease. (PubMed id 9195529)9 Wong M....Fish E.N. (J. Rheumatol. 1997)
    391. Migration responses of human monocytic cell lines to alpha- and beta-chemokines. (PubMed id 9237815)9 Cross A.K....Rees R.C. (Cytokine 1997)
    392. Suppression of HIV-1 transcription by beta-chemokines RANTES, MIP1-alpha, and MIP-1beta is not mediated by the NFAT-1 enhancer element. (PubMed id 9237650)9 Handen J.S. and Rosenberg H.F. (FEBS Lett. 1997)
    393. Anti-MIP-1alpha and anti-RANTES antibodies: new allies of HIV-1? (PubMed id 9281393)9 Kissler S....Opelz G. (Clin. Immunol. Immunopathol. 1997)
    394. The second extracellular loop of CCR5 is the major determinant of ligand specificity. (PubMed id 9312096)9 Samson M....Parmentier M. (J. Biol. Chem. 1997)
    395. Cloning and characterization of a novel murine macrophage inflammatory protein-1 alpha receptor. (PubMed id 8662890)9 Meyer A....Power C.A. (J. Biol. Chem. 1996)
    396. Constitutive expression of various chemokine genes in human T-cell lines infected with human T-cell leukemia virus type 1: role of the viral transactivator Tax. (PubMed id 8608955)9 Baba M....Yoshie O. (Int. J. Cancer 1996)
    397. Cytokines induced by Sendai virus in human peripheral blood leukocytes. (PubMed id 8699116)9 Hua J....Rashidbaigi A. (J. Leukoc. Biol. 1996)
    398. Pulmonary infection of mice with human metapneumovirus induces local cytotoxic T-cell and immunoregulatory cytokine responses similar to those seen with human respiratory syncytial virus. (PubMed id 20053825)9 Herd K.A....Tindle R.W. (J. Gen. Virol. 2010)
    399. Suppressive effect of insulin infusion on chemokines and chemokine receptors. (PubMed id 20200310)9 Ghanim H....Dandona P. (Diabetes Care 2010)
    400. T-cell receptor gene-modified T cells with shared renal cell carcinoma specificity for adoptive T-cell therapy. (PubMed id 20371691)9 Leisegang M....Noessner E. (Clin. Cancer Res. 2010)
    401. Meconium-induced release of cytokines is mediated by the TRL4/MD-2 complex in a CD14-dependent manner. (PubMed id 20092898)9 Salvesen B....Mollnes T.E. (Mol. Immunol. 2010)
    402. Rapamycin protects mice from staphylococcal enterotoxin B-induced toxic shock and blocks cytokine release in vitro and in vivo. (PubMed id 20086156)9 Krakauer T....Fox S.D. (Antimicrob. Agents Chemother. 2010)
    403. IL-2-driven regulation of NK cell receptors with regard to the distribution of CD16+ and CD16- subpopulations and in vivo influence after haploidentical NK cell infusion. (PubMed id 20145545)9 Huenecke S....Koehl U. (J. Immunother. 2010)
    404. Targeted knock down of CCL22 and CCL17 by siRNA during DC differentiation and maturation affects the recruitment of T subsets. (PubMed id 19450895)9 Kang S....Luo R. (Immunobiology 2010)
    405. Human peritoneal macrophages from ascitic fluid can be infected by a broad range of HIV-1 isolates. (PubMed id 20065862)9 Chang T.L....Branch A. (J. Acquir. Immune Defic. Syndr. 2010)
    406. IL-8 in cerebrospinal fluid from children with acute encephalopathy is higher than in that from children with febrile seizure. (PubMed id 20500697)9 Asano T....Fukunaga Y. (Scand. J. Immunol. 2010)
    407. Administered CpG oligodeoxynucleotide induces mRNA expression of CXC and CC chemokines at the intestinal mucosa and PBMCs in piglets. (PubMed id 20202485)9 Cheng Q....Zhang M. (Int. Immunopharmacol. 2010)
    408. Effect of non-nucleoside reverse transcriptase inhibitors on cytokine, chemokine, and immunoglobulin profiles in serum and genital secretions of HIV-infected women. (PubMed id 20187769)9 Sachdeva R.K....Sharma M. (amp 2010)
    409. Local production of inflammatory mediators during childhood parainfluenza virus infection. (PubMed id 20182399)9 El Feghaly R.E....Domachowske J.B. (Pediatr. Infect. Dis. J. 2010)
    410. Regulation of human NK-cell cytokine and chemokine production by target cell recognition. (PubMed id 19965656)9 Fauriat C....Bryceson Y.T. (Blood 2010)
    411. Phospholipase D1 mediates TNFalpha-induced inflammation in a murine model of TNFalpha-induced peritonitis. (PubMed id 20463923)9 Sethu S....Melendez A.J. (PLoS ONE 2010)
    412. Off-pump coronary artery bypass surgery is associated with fewer gene expression changes in the human myocardium in comparison with on-pump surgery. (PubMed id 20332183)9 Ghorbel M.T....Angelini G.D. (Physiol. Genomics 2010)
    413. Resistance to Simian HIV infection is associated with high plasma interleukin-8, RANTES and Eotaxin in a macaque model of repeated virus challenges. (PubMed id 20164782)9 Promadej-Lanier N....Kersh E.N. (J. Acquir. Immune Defic. Syndr. 2010)
    414. Improved survival of mice deficient in secretory immunoglobulin M following systemic infection with Cryptococcus neoformans. (PubMed id 19901068)9 Subramaniam K.S....Pirofski L.A. (Infect. Immun. 2010)
    415. The association of luteinizing hormone and follicle-stimulating hormone with cytokines and markers of disease activity in rheumatoid arthritis: a case-control study. (PubMed id 20337546)9 KAYss A.S....rre A.9.T. (Scand. J. Rheumatol. 2010)
    416. Human eosinophils recognize endogenous danger signal crystalline uric acid and produce proinflammatory cytokines mediated by autocrine ATP. (PubMed id 20483787)9 Kobayashi T....Kita H. (J. Immunol. 2010)
    417. The role of adenosine receptors in regulating production of tumour necrosis factor-alpha and chemokines by human lung macrophages. (PubMed id 20136829)9 Buenestado A....Devillier P. (Br. J. Pharmacol. 2010)
    418. Cytokine expression in placenta-derived mesenchymal stem cells in patients with pre-eclampsia and normal pregnancies. (PubMed id 19819721)9 Hwang J.H....Oh M.J. (Cytokine 2010)
    419. IL-17 is elevated in cerebrospinal fluids in bacterial meningitis in children. (PubMed id 20350814)9 Asano T....Fukunaga Y. (Cytokine 2010)
    420. Multiple osteolytic bone lesions with high serum levels of interleukin-6 and CCL chemokines in a patient with adult T cell leukemia. (PubMed id 18177436)9 Chiba K....Asaka M. (Int J Lab Hematol 2009)
    421. Inflammation in methotrexate-induced pulmonary toxicity occurs via the p38 MAPK pathway. (PubMed id 19100307)9 Kim Y.J....Ryu J.C. (Toxicology 2009)
    422. Secretory products from human adipocytes stimulate proinflammatory cytokine secretion from human endothelial cells. (PubMed id 19173302)9 Sommer G....Fasshauer M. (J. Cell. Biochem. 2009)
    423. Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cells. (PubMed id 19308771)9 Berg M....Childs R. (Cytotherapy 2009)
    424. Increased levels of inflammatory chemokines in amyotrophic lateral sclerosis. (PubMed id 19236470)9 Kuhle J....Czaplinski A. (Eur. J. Neurol. 2009)
    425. Effect of an extract based on the medicinal mushroom Agaricus blazei murill on release of cytokines, chemokines and leukocyte growth factors in human blood ex vivo and in vivo. (PubMed id 19281536)9 Johnson E....Hetland G. (Scand. J. Immunol. 2009)
    426. Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza. (PubMed id 20003352)9 Bermejo-Martin J.F....Kelvin D.J. (Crit Care 2009)
    427. Systemic cytokine response profiles associated with respiratory virus-induced acute otitis media. (PubMed id 19352211)9 Patel J.A....Chonmaitree T. (Pediatr. Infect. Dis. J. 2009)
    428. Intracellular protein phosphorylation in eosinophils and the functional relevance in cytokine production. (PubMed id 19494504)9 Yamamura K....Ohta K. (Int. Arch. Allergy Immunol. 2009)
    429. C5a enhances dysregulated inflammatory and angiogenic responses to malaria in vitro: potential implications for placental malaria. (PubMed id 19308263)9 Conroy A....Kain K.C. (PLoS ONE 2009)
    430. Wound age estimation by simultaneous detection of 9 cytokines in human dermal wounds with a multiplex bead-based immunoassay: an estimative method using outsourced examinations. (PubMed id 19419898)9 Takamiya M....Aoki Y. (Leg Med (Tokyo) 2009)
    431. Modified vaccinia virus ankara triggers chemotaxis of monocytes and early respiratory immigration of leukocytes by induction of CCL2 expression. (PubMed id 19129447)9 Lehmann M.H....Sutter G. (J. Virol. 2009)
    432. Cytokine and autoantibody profiling related to histopathological features in primary Sjogren's syndrome. (PubMed id 19574472)9 Reksten T.R....Brokstad K.A. (Rheumatology (Oxford) 2009)
    433. Odontoblasts in the dental pulp immune response. (PubMed id 19067439)9 Farges J.C....Staquet M.J. (J. Exp. Zool. B Mol. Dev. Evol. 2009)
    434. Kinetics of plasma cytokines and chemokines during primary HIV-1 infection and after analytical treatment interruption. (PubMed id 19200172)9 Barqasho B....SAPnnerborg A. (HIV Med. 2009)
    435. Purification method using iodixanol (OptiPrep)-based density gradient significantly reduces cytokine chemokine production from human islet preparations, leading to prolonged beta-cell survival during pretransplantation culture. (PubMed id 19249543)9 Mita A....Ichii H. (Transplant. Proc. 2009)
    436. M1 and M2a polarization of human monocyte-derived macrophages inhibits HIV-1 replication by distinct mechanisms. (PubMed id 19414777)9 Cassol E....Poli G. (J. Immunol. 2009)
    437. Host markers in QuantiFERON supernatants differentiate active TB from latent TB infection: preliminary report. (PubMed id 19445695)9 Chegou N.N....Walzl G. (BMC Pulm Med 2009)
    438. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced chemokine release in both TRAIL-resistant and TRAIL-sensitive cells via nuclear factor kappa B. (PubMed id 19120450)9 Tang W....Zheng D. (FEBS J. 2009)
    439. Lipomatosis-associated inflammation and excess collagen may contribute to lower relative resting energy expenditure in women with adiposis dolorosa. (PubMed id 19621017)9 Herbst K.L....Boyle D.L. (Int J Obes (Lond) 2009)
    440. Gene expression in HIV-1/Mycobacterium tuberculosis co-infected macrophages is dominated by M. tuberculosis. (PubMed id 19520608)9 Maddocks S....Britton W.J. (Tuberculosis (Edinb) 2009)
    441. Cytokine profiles in toxoplasmic and viral uveitis. (PubMed id 19302012)9 Lahmar I....Candolfi E. (J. Infect. Dis. 2009)
    442. Varicose veins show enhanced chemokine expression. (PubMed id 19729323)9 SolA! L.d.e.l. .R....GarcA-a-RodrA-guez C. (Eur J Vasc Endovasc Surg 2009)
    443. The effect of topical amphotericin B on inflammatory markers in patients with chronic rhinosinusitis: a multicenter randomized controlled study. (PubMed id 19160404)9 Ebbens F.A....Fokkens W.J. (Laryngoscope 2009)
    444. Differentiated human alveolar type II cells secrete antiviral IL-29 (IFN-lambda 1) in response to influenza A infection. (PubMed id 19155475)9 Wang J....Mason R.J. (J. Immunol. 2009)
    445. Differential cytokine secretion and early treatment response in patients with pulmonary tuberculosis. (PubMed id 19196252)9 Djoba Siawaya J.F....Walzl G. (Clin. Exp. Immunol. 2009)
    446. Early cytokine production risk stratifies trauma patients for multiple organ failure. (PubMed id 19717036)9 Jastrow K.M....Mercer D.W. (J. Am. Coll. Surg. 2009)
    447. Local and systemic chemokine patterns in a human musculoskeletal trauma model. (PubMed id 19274438)9 Bastian D....ReikerAYs O. (Inflamm. Res. 2009)
    448. Attenuated D2 16681-PDK53 vaccine: defining humoral and cell-mediated immunity. (PubMed id 19355961)9 Rabablert J. and Yoksan S. (Curr. Pharm. Des. 2009)
    449. Cytokine production by human herpesvirus 8-infected dendritic cells. (PubMed id 19088276)9 Hensler H.R....Jenkins F.J. (J. Gen. Virol. 2009)
    450. Borrelia burgdorferi stimulates macrophages to secrete higher levels of cytokines and chemokines than Borrelia afzelii or Borrelia garinii. (PubMed id 19909078)9 Strle K....Steere A.C. (J. Infect. Dis. 2009)
    451. Effect of head and neck cancer supernatant and CpG-oligonucleotides on migration and IFN-alpha production of plasmacytoid dendritic cells. (PubMed id 19661310)9 Thiel A....Wollenberg B. (Anticancer Res. 2009)
    452. Polybrominated diphenyl ether exposure suppresses cytokines important in the defence to coxsackievirus B3 infection in mice. (PubMed id 19022362)9 Lundgren M....IlbAock N.G. (Toxicol. Lett. 2009)
    453. Bronchoalveolar lavage fluid cellular characteristics, functional parameters and cytokine and chemokine levels in interstitial lung diseases. (PubMed id 19281539)9 Vasakova M....Striz I. (Scand. J. Immunol. 2009)
    454. Fibroblasts regulate monocyte response to ECM-derived matrix: the effects on monocyte adhesion and the production of inflammatory, matrix remodeling, and growth factor proteins. (PubMed id 19437738)9 Chung A.S. and Kao W.J. (J Biomed Mater Res A 2009)
    455. Leishmania infantum amastigotes enhance HIV-1 production in cocultures of human dendritic cells and CD4 T cells by inducing secretion of IL-6 and TNF-alpha. (PubMed id 19468304)9 Garg R....Tremblay M.J. (PLoS Negl Trop Dis 2009)
    456. Differential patterns of 27 cord blood immune biomarkers across gestational age. (PubMed id 19403498)9 Matoba N....Wang X. (Pediatrics 2009)
    457. Differential cytokine/chemokines and KL-6 profiles in patients with different forms of tuberculosis. (PubMed id 19570688)9 Djoba Siawaya J.F....Walzl G. (Cytokine 2009)
    458. TRAIL receptor mediates inflammatory cytokine release in an NF-kappaB-dependent manner. (PubMed id 19434100)9 Tang W....Zheng D. (Cell Res. 2009)
    459. Polyfunctional CD4+ T-cell induction in neutralizing antibody-triggered control of simian immunodeficiency virus infection. (PubMed id 19297503)9 Yamamoto T....Matano T. (J. Virol. 2009)
    460. Expression of markers of regulatory CD4+CD25+foxp3+ cells in atherosclerotic plaques of human coronary arteries. (PubMed id 19902068)9 Sokolov V.O....Arefieva T.I. (Bull. Exp. Biol. Med. 2009)
    461. Cellular injury and neuroinflammation in children with chronic intractable epilepsy. (PubMed id 20021679)9 Choi J....Koh S. (J Neuroinflammation 2009)
    462. Modification of cell-surface thiols elicits activation of human monocytic cell line THP-1: possible involvement in effect of haptens 2,4-dinitrochlorobenzene and nickel sulfate. (PubMed id 19336971)9 Hirota M....Itagaki H. (J Toxicol Sci 2009)
    463. Association of cord blood cytokine levels with wheezy infants in the first year of life. (PubMed id 19438981)9 Tadaki H....Morikawa A. (Pediatr Allergy Immunol 2009)
    464. Differential innate immune responses of a living skin equivalent model colonized by Staphylococcus epidermidis or Staphylococcus aureus. (PubMed id 19054079)9 Holland D.B....Holland K.T. (FEMS Microbiol. Lett. 2009)
    465. The balance between pro- and anti-inflammatory cytokines is associated with platelet aggregability in acute coronary syndrome patients. (PubMed id 18486134)9 Gori A.M....Abbate R. (Atherosclerosis 2009)
    466. CXC and CC chemokines induced in human renal epithelial cells by inflammatory cytokines. (PubMed id 19594487)9 Thorburn E....Striz I. (APMIS 2009)
    467. GB virus type C interactions with HIV: the role of envelope glycoproteins. (PubMed id 19758271)9 Mohr E.L. and Stapleton J.T. (J. Viral Hepat. 2009)
    468. Ovarian cancer-associated ascites demonstrates altered immune environment: implications for antitumor immunity. (PubMed id 19661290)9 Giuntoli R.L....Oelke M. (Anticancer Res. 2009)
    469. Interleukin-8 and RANTES are signature cytokines made by HOZOT, a new type of regulatory T cells. (PubMed id 19699525)9 Harashima A....Kibata M. (Mol. Immunol. 2009)
    470. Allergic reaction induced by dermal and/or respiratory exposure to low-dose phenoxyacetic acid, organophosphorus, and carbamate pesticides. (PubMed id 19467290)9 Fukuyama T....Kosaka T. (Toxicology 2009)
    471. Changes in circulating cytokine levels in midlife women with psychological symptoms with selective serotonin reuptake inhibitor and Japanese traditional medicine. (PubMed id 19179025)9 Yasui T....Irahara M. (Maturitas 2009)
    472. Systemic inflammatory response and downmodulation of peripheral CD25+Foxp3+ T-regulatory cells in patients undergoing radiofrequency thermal ablation for lung cancer. (PubMed id 19332094)9 Fietta A.M....Meloni F. (Hum. Immunol. 2009)
    473. Paracrine and juxtacrine lymphocyte enhancement of adherent macrophage and foreign body giant cell activation. (PubMed id 18437695)9 Chang D.T....Anderson J.M. (J Biomed Mater Res A 2009)
    474. Circulating chemokine levels in febrile infants with serious bacterial infections. (PubMed id 19951848)9 Chen H.L....Yang R.C. (Kaohsiung J. Med. Sci. 2009)
    475. Effect of dexamethasone on respiratory syncytial virus-induced lung inflammation in children: results of a randomized, placebo controlled clinical trial. (PubMed id 19397752)9 Somers C.C....Jafri H.S. (Pediatr Allergy Immunol 2009)
    476. Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment. (PubMed id 19293190)9 Harlin H....Gajewski T.F. (Cancer Res. 2009)
    477. Role of cytokines and chemokines in idiopathic inflammatory myopathies. (PubMed id 19726994)9 De Paepe B....De Bleecker J.L. (Curr Opin Rheumatol 2009)
    478. CCR1 and CCR5 promote hepatic fibrosis in mice. (PubMed id 19603542)9 Seki E....Schwabe R.F. (J. Clin. Invest. 2009)
    479. Novel cellular and molecular mechanisms of induction of immune responses by aluminum adjuvants. (PubMed id 19439372)9 Aimanianda V....Bayry J. (Trends Pharmacol. Sci. 2009)
    480. Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages. (PubMed id 18774390)9 Goleva E....Leung D.Y. (J. Allergy Clin. Immunol. 2008)
    481. Suppression of viral replication with highly active antiretroviral therapy has no impact on the functional profile of HIV-specific CD8(+) T cells. (PubMed id 18421792)9 LA^pez M....Benito J.M. (Eur. J. Immunol. 2008)
    482. Activation of T-cells from allergic patients and volunteers by p-phenylenediamine and Bandrowski's base. (PubMed id 17914451)9 Coulter E.M....Naisbitt D.J. (J. Invest. Dermatol. 2008)
    483. Cryopreserved peripheral blood mononuclear cells are suitable for the assessment of immunological markers in type 1 diabetic children. (PubMed id 18761006)9 Axelsson S....Casas R. (Cryobiology 2008)
    484. Myeloma cell expression of 10 candidate genes for osteolytic bone disease. Only overexpression of DKK1 correlates with clinical bone involvement at diagnosis. (PubMed id 18005268)9 Haaber J....Rasmussen T. (Br. J. Haematol. 2008)
    485. Ex vivo simulation of IgG Fc and T-cell receptor functions: an application to inflammatory bowel disease. (PubMed id 18340639)9 Mitsuhashi M. and Targan S.R. (Inflamm. Bowel Dis. 2008)
    486. CC family chemokines directly regulate myoblast responses to skeletal muscle injury. (PubMed id 18566004)9 Yahiaoui L....Petrof B.J. (J. Physiol. (Lond.) 2008)
    487. Activation of an immunoregulatory and antiviral gene expression program in poly(I:C)-transfected human neutrophils. (PubMed id 18941247)9 Tamassia N....Cassatella M.A. (J. Immunol. 2008)
    488. Host inflammatory response profiling in preeclampsia using an in vitro whole blood stimulation model. (PubMed id 18293200)9 Brewster J.A....Walker J.J. (Hypertens Pregnancy 2008)
    489. Clinical efficacy and cytokine network-modulating effects of tacrolimus in myasthenia gravis. (PubMed id 18262659)9 Furukawa Y....Yamada M. (J. Neuroimmunol. 2008)
    490. Oxytocin alleviates the neuroendocrine and cytokine response to bacterial endotoxin in healthy men. (PubMed id 18593851)9 Clodi M....Luger A. (Am. J. Physiol. Endocrinol. Metab. 2008)
    491. Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis. (PubMed id 18955666)9 Kaya Z....Katus H.A. (Circulation 2008)
    492. [Chronic HCV-infection and expression of mRNA of CC-chemokines and their receptors]. (PubMed id 18822499)9 Zhdanov K.V....Totolian A.A. (Zh. Mikrobiol. Epidemiol. Immunobiol. 2008)
    493. Simultaneous detection of eight analytes in human serum by two commercially available platforms for multiplex cytokine analysis. (PubMed id 18003817)9 Toedter G....Brodmerkel C. (Clin. Vaccine Immunol. 2008)
    494. Differences in amniotic fluid and maternal serum cytokine levels in early midtrimester women without evidence of infection. (PubMed id 18703348)9 Chow S.S....Rawlinson W.D. (Cytokine 2008)
    495. Impaired CD4 and CD8 T cell phenotype and reduced chemokine secretion in recent-onset type 1 diabetic children. (PubMed id 18803760)9 Hedman M....Casas R. (Clin. Exp. Immunol. 2008)
    496. Combination of recombinant human growth hormone and propranolol decreases hypermetabolism and inflammation in severely burned children. (PubMed id 18477935)9 Jeschke M.G....Herndon D.N. (Pediatr Crit Care Med 2008)
    497. Polyfunctional T cell responses are a hallmark of HIV-2 infection. (PubMed id 18200635)9 Duvall M.G....Koup R.A. (Eur. J. Immunol. 2008)
    498. Multicentric Castleman disease is associated with polyfunctional effector memory HHV-8-specific CD8+ T cells. (PubMed id 18000163)9 Guihot A....Carcelain G. (Blood 2008)
    499. A pilot study to explore the usefulness of antibody array in childhood atopic dermatitis. (PubMed id 18507202)9 Hon K.L....Leung A.K. (J Natl Med Assoc 2008)
    500. Virological outcome after structured interruption of antiretroviral therapy for human immunodeficiency virus infection is associated with the functional profile of virus-specific CD8+ T cells. (PubMed id 18234797)9 Daucher M....Douek D.C. (J. Virol. 2008)
    501. Cellular and molecular mechanisms of fibrosis. (PubMed id 18161745)9 Wynn T.A. (J. Pathol. 2008)
    502. Combined inhibition of complement and CD14 abolish E. coli-induced cytokine-, chemokine- and growth factor-synthesis in human whole blood. (PubMed id 18606453)9 Brekke O.L....Mollnes T.E. (Mol. Immunol. 2008)
    503. [Expression of chemokines and cytokines in atherosclerotic plaques and internal membrane of the arteries in patients with coronary artery disease]. (PubMed id 18491584)9 Kukhtina N.B....Krasnikova T.L. (Ter. Arkh. 2008)
    504. Rational design of novel HIV-1 entry inhibitors by RANTES engineering. (PubMed id 18243436)9 Vangelista L....Lusso P. (Vaccine 2008)
    505. A new dendritic cell type suitable as sentinel of contact allergens. (PubMed id 18547706)9 Schreiner M....Wanner R. (Toxicology 2008)
    506. Seven week culture of functional human mast cells from buffy coat preparations. (PubMed id 18547584)9 Holm M....tz P.O. (J. Immunol. Methods 2008)
    507. Expression and functional significance of SOCS-1 and SOCS-3 in astrocytes. (PubMed id 18713987)9 Qin H....Benveniste E.N. (J. Immunol. 2008)
    508. [Mechanisms for formation of myeloma bone disease]. (PubMed id 18379024)9 Yata K....Matsumoto T. (Clin Calcium 2008)
    509. Local and systemic release of cytokines, nerve growth factor, prostaglandin E2, and substance P in incisional wounds and serum following cesarean delivery. (PubMed id 18394968)9 Carvalho B....Angst M.S. (J Pain 2008)
    510. Complement is an essential component of the immune response to adeno-associated virus vectors. (PubMed id 18199646)9 Zaiss A.K....Muruve D.A. (J. Virol. 2008)
    511. The adjuvants aluminum hydroxide and MF59 induce monocyte and granulocyte chemoattractants and enhance monocyte differentiation toward dendritic cells. (PubMed id 18390722)9 Seubert A....Wack A. (J. Immunol. 2008)
    512. DNA gag/adenovirus type 5 (Ad5) gag and Ad5 gag/Ad5 gag vaccines induce distinct T-cell response profiles. (PubMed id 18524823)9 Cox K.S....Casimiro D.R. (J. Virol. 2008)
    513. Serum cytokine and chemokine profiles in neonates with meconium aspiration syndrome. (PubMed id 18346989)9 Okazaki K....Kimura H. (Pediatrics 2008)
    514. Simvastatin reduces Chlamydophila pneumoniae-mediated histone modifications and gene expression in cultured human endothelial cells. (PubMed id 18309103)9 Schmeck B....Hippenstiel S. (Circ. Res. 2008)
    515. Decreased cytokine and chemokine mRNA expression in bronchoalveolar lavage in asymptomatic smoking subjects. (PubMed id 18230951)9 Meuronen A....Laitinen A. ( international review of thoracic diseases 2008)
    516. [Effects of hMIP-1beta gene modification on in vivo tumorigenicity and vaccine efficacy of tumor cells]. (PubMed id 18646689)9 Luo X.L....Liang A.M. (Zhonghua Zhong Liu Za Zhi 2008)
    517. Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents pulmonary inflammation in patients without preexisting lung injury. (PubMed id 18156881)9 Wolthuis E.K....Schultz M.J. (Anesthesiology 2008)
    518. Retinoid acid inhibits IL-1-induced iNOS, COX-2 and chemokine production in human chondrocytes. (PubMed id 18821215)9 Hung L.F....Ho L.J. (Immunol. Invest. 2008)
    519. Expression analysis of CCL27 and CCL28 mRNA in lesional and non-lesional skin of dogs with atopic dermatitis. (PubMed id 18250572)9 Maeda S....Kitagawa H. (J. Vet. Med. Sci. 2008)
    520. Anti-inflammatory effects of besifloxacin, a novel fluoroquinolone, in primary human corneal epithelial cells. (PubMed id 19085374)9 Zhang J.Z....Ward K.W. (Curr. Eye Res. 2008)
    521. NF-kappa B modulates sensitivity to apoptosis, proinflammatory and migratory potential in short- versus long-term cultured human gamma delta lymphocytes. (PubMed id 18941174)9 Ferrarini M....Biswas P. (J. Immunol. 2008)
    522. Associations of circulating adiponectin with estradiol and monocyte chemotactic protein-1 in postmenopausal women. (PubMed id 18347511)9 Miyatani Y....Irahara M. (Menopause 2008)
    523. Bromelain treatment decreases secretion of pro-inflammatory cytokines and chemokines by colon biopsies in vitro. (PubMed id 18160345)9 Onken J.E....Hale L.P. (Clin. Immunol. 2008)
    524. The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent. (PubMed id 18085644)9 LappegAYrd K.T....Mollnes T.E. (J Biomed Mater Res A 2008)
    525. Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India. (PubMed id 18489763)9 Jain V....Stiles J.K. (Malar. J. 2008)
    526. Cytokine secretion depends on Galalpha(1,3)Gal expression in a pig-to-human whole blood model. (PubMed id 18424758)9 Saethre M....Mollnes T.E. (J. Immunol. 2008)
    527. Macrophage inflammatory protein-3alpha influences growth of K562 leukemia cells in co-culture with anticancer drug-pretreated HS-5 stromal cells. (PubMed id 18538911)9 Lee Y.C....Chu S.T. (Toxicology 2008)
    528. Upregulation of chemokine expression in murine cornea due to mechanical trauma or endotoxin. (PubMed id 17993576)9 Pillai R.G....George A.J. (Br J Ophthalmol 2008)
    529. Liver X receptor is a key regulator of cytokine release in human monocytes. (PubMed id 17724434)9 Myhre A.E....Wang J.E. (Shock 2008)
    530. Kinetic profiles of 18 systemic pro- and anti-inflammatory mediators during and following exercise in children. (PubMed id 18341089)9 Rosa J.S....Galassetti P.R. (amp 2007)
    531. Identification of a human CD8+ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4. (PubMed id 17483450)9 Joosten S.A....Ottenhoff T.H. (Proc. Natl. Acad. Sci. U.S.A. 2007)
    532. Attenuating characteristics of DEN-2 PDK53 in flavivirus-naA^ve peripheral blood mononuclear cells. (PubMed id 17316931)9 Rabablert J....Ubol S. (Vaccine 2007)
    533. Preserved central memory and activated effector memory CD4+ T-cell subsets in human immunodeficiency virus controllers: an ANRS EP36 study. (PubMed id 17928341)9 Potter S.J....Chakrabarti L.A. (J. Virol. 2007)
    534. Gene expression changes in peripheral blood mononuclear cells during measles virus infection. (PubMed id 17538120)9 Zilliox M.J....Griffin D.E. (Clin. Vaccine Immunol. 2007)
    535. Efficient replication of pneumonia virus of mice (PVM) in a mouse macrophage cell line. (PubMed id 17547763)9 Dyer K.D....Rosenberg H.F. (Virol. J. 2007)
    536. Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone. (PubMed id 17517970)9 Coutanceau E....Demangel C. (J. Exp. Med. 2007)
    537. Eosinophil recruiting chemokines are down-regulated in peripheral blood mononuclear cells of allergic patients treated with deflazacort or desloratadine. (PubMed id 18179747)9 Di Sciascio M.B....Di Gioacchino M. (Int J Immunopathol Pharmacol 2007)
    538. Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children. (PubMed id 17997848)9 Armah H.B....Stiles J.K. (Malar. J. 2007)
    539. [The utility of exhaled breath condensate analysis for asthma management]. (PubMed id 17511269)9 Matsunaga K. (Rinsho Byori 2007)
    540. Seminal plasma cytokines and chemokines in prostate inflammation: interleukin 8 as a predictive biomarker in chronic prostatitis/chronic pelvic pain syndrome and benign prostatic hyperplasia. (PubMed id 16905241)9 Penna G....Adorini L. (Eur. Urol. 2007)
    541. Effects of maternal exposure to LPS on the inflammatory response in the offspring. (PubMed id 17706793)9 Lasala N. and Zhou H. (J. Neuroimmunol. 2007)
    542. Multiplex analysis of serum cytokines in melanoma patients treated with interferon-alpha2b. (PubMed id 17438101)9 Yurkovetsky Z.R....Lokshin A.E. (Clin. Cancer Res. 2007)
    543. Expression of interferon-gamma- inducible protein-10 and its receptor CXCR3 in chronic pancreatitis. (PubMed id 17912012)9 Singh L....Wig J.D. (Pancreatology 2007)
    544. Modulation of chemokines by staphylococcal superantigen in atopic dermatitis. (PubMed id 17369706)9 Homey B....Lauerma A. (Chem Immunol Allergy 2007)
    545. Therapeutic T cells induce tumor-directed chemotaxis of innate immune cells through tumor-specific secretion of chemokines and stimulation of B16BL6 melanoma to secrete chemokines. (PubMed id 18001476)9 Winter H....Hu H.M. (J Transl Med 2007)
    546. Tyrosine kinase Syk associates with toll-like receptor 4 and regulates signaling in human monocytic cells. (PubMed id 17228323)9 Chaudhary A....Naranjo M.J. (Immunol. Cell Biol. 2007)
    547. Chemokine production predominates in human monocytes infected with Tula virus. (PubMed id 17425435)9 Cebalo L. and MarkotiA8 A. (Viral Immunol. 2007)
    548. Early posttransplant inflammation promotes the development of alloimmunity and chronic human lung allograft rejection. (PubMed id 17264811)9 Bharat A....Mohanakumar T. (Transplantation 2007)
    549. Cytokine and chemokine expression in humans infected with Sudan Ebola virus. (PubMed id 17940971)9 Hutchinson K.L. and Rollin P.E. (J. Infect. Dis. 2007)
    550. Protein microarrays and quantum dot probes for early cancer detection. (PubMed id 17408931)9 Zajac A....Zhukov T. (Colloids Surf B Biointerfaces 2007)
    551. Trophoblast-macrophage interactions: a regulatory network for the protection of pregnancy. (PubMed id 17156192)9 Fest S....Mor G. (Am. J. Reprod. Immunol. 2007)
    552. Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs. (PubMed id 16943231)9 Malvitte L....Lizard G. (Br J Ophthalmol 2007)
    553. Predominance of Th2 cytokines, CXC chemokines and innate immunity mediators at the mucosal level during severe respiratory syncytial virus infection in children. (PubMed id 17823085)9 Bermejo-Martin J.F....Blanco-Quiros A. (Eur. Cytokine Netw. 2007)
    554. Influence of the fungal NF-kappaB inhibitor panepoxydone on inflammatory gene expression in MonoMac6 cells. (PubMed id 17386409)9 Erkel G....Anke T. (Int. Immunopharmacol. 2007)
    555. Concentrations and significance of cytokines and other immunologic factors in semen of healthy fertile men. (PubMed id 17855405)9 Politch J.A....Anderson D.J. (Hum. Reprod. 2007)
    556. Early-life risk factors for occurrence of atopic dermatitis during the first year. (PubMed id 17332188)9 Sugiyama M....Morikawa A. (Pediatrics 2007)
    557. Minocycline and sulforaphane inhibited lipopolysaccharide-mediated retinal microglial activation. (PubMed id 17653053)9 Yang L.P....Tso M.O. (Mol. Vis. 2007)
    558. Adipokines oversecreted by omental adipose tissue in human obesity. (PubMed id 17578888)9 Maury E....Brichard S.M. (Am. J. Physiol. Endocrinol. Metab. 2007)
    559. Inverse association of plasma IL-13 and inflammatory chemokines with lung function impairment in stable COPD: a cross-sectional cohort study. (PubMed id 17868461)9 Lee J.S....Sciurba F.C. (Respir. Res. 2007)
    560. Cytokines in human breast cyst fluid. (PubMed id 17467271)9 Parish D.C....Reed M.J. (J. Steroid Biochem. Mol. Biol. 2007)
    561. Complement activation and cytokine response by BioProtein, a bacterial single cell protein. (PubMed id 17302729)9 Sikkeland L.I....Mollnes T.E. (Clin. Exp. Immunol. 2007)
    562. Mediators and cytokines in allergic and viral-triggered rhinitis. (PubMed id 17883911)9 Klemens C....Kramer M.F. (Allergy Asthma Proc 2007)
    563. Circulating cytokines in Norwegian patients with psoriatic arthritis determined by a multiplex cytokine array system. (PubMed id 16936328)9 Szodoray P....Centola M. (Rheumatology (Oxford) 2007)
    564. Hev b 6.01 and Hev b 5 induce pro-inflammatory cytokines and chemokines from peripheral blood mononuclear cells in latex allergy. (PubMed id 17210051)9 Lehto M....Alenius H. (Clin. Exp. Allergy 2007)
    565. Serum chemokine profiles in patients with alopecia areata. (PubMed id 17489976)9 Kuwano Y....Tamaki K. (Br. J. Dermatol. 2007)
    566. Mucosal safety of PHI-443 and stampidine as a combination microbicide to prevent genital transmission of HIV-1. (PubMed id 17498709)9 D'Cruz O.J. and Uckun F.M. (Fertil. Steril. 2007)
    567. High levels of inflammatory chemokines and cytokines in joint fluid and synovial tissue throughout the course of antibiotic-refractory lyme arthritis. (PubMed id 17393419)9 Shin J.J....Steere A.C. (Arthritis Rheum. 2007)
    568. Multiplex bead analysis of vitreous humor of patients with vitreoretinal disorders. (PubMed id 17460280)9 Banerjee S....Murray P.I. (amp 2007)
    569. Chemokines and chemokine receptors in renal transplantation--from bench to bedside. (PubMed id 17444276)9 Fischereder M. (Acta Physiol Hung 2007)
    570. Relationship between adipocyte size and adipokine expression and secretion. (PubMed id 17164304)9 Skurk T....Hauner H. (J. Clin. Endocrinol. Metab. 2007)
    571. Chemokines and chemokine receptors in multiple sclerosis. Potential targets for new therapies. (PubMed id 17295707)9 SzczuciA8ski A. and Losy J. (Acta Neurol. Scand. 2007)
    572. Escape from immune surveillance by Capnocytophaga canimorsus. (PubMed id 17205476)9 Shin H....Cornelis G.R. (J. Infect. Dis. 2007)
    573. Infection of human primary hepatocytes with dengue virus serotype 2. (PubMed id 17245728)9 Suksanpaisan L....Smith D.R. (J. Med. Virol. 2007)
    574. Serum chemokine profile in patients with bullous pemphigoid. (PubMed id 17300233)9 Nakashima H....Tamaki K. (Br. J. Dermatol. 2007)
    575. Secretion of cytokines in breast cancer cells: the molecular mechanism of procathepsin D proliferative effects. (PubMed id 17348817)9 Fusek M....Vetvicka V. (amp 2007)
    576. Airway inflammation in paper mill workers. (PubMed id 18000418)9 Sikkeland L.I....Kongerud J. (J. Occup. Environ. Med. 2007)
    577. The immunomodulatory effect of sevoflurane in endotoxin-injured alveolar epithelial cells. (PubMed id 17312223)9 Suter D....Beck-Schimmer B. (Anesth. Analg. 2007)
    578. Successful HAART is associated with high B-chemokine levels in chronic HIV type 1-infected patients. (PubMed id 17678475)9 Brito A....Casseb J. (AIDS Res. Hum. Retroviruses 2007)
    579. Preclinical evaluation of synthetic -2 RANTES as a candidate vaginal microbicide to target CCR5. (PubMed id 16569870)9 Kish-Catalone T.M....DeVico A.L. (Antimicrob. Agents Chemother. 2006)
    580. Type-2 dominant cytokine gene expression following hepatic surgery. (PubMed id 17013720)9 Khatri V.P....Rodriguez-Bigas M.A. (J Hepatobiliary Pancreat Surg 2006)
    581. Functional genomics of innate host defense molecules in normal human monocytes in response to Aspergillus fumigatus. (PubMed id 16552065)9 Cortez K.J....Walsh T.J. (Infect. Immun. 2006)
    582. Ibuprofen use, endotoxemia, inflammation, and plasma cytokines during ultramarathon competition. (PubMed id 16554145)9 Nieman D.C....Morrow J.D. (Brain Behav. Immun. 2006)
    583. Interferon-beta modulates bone-associated cytokines and osteoclast precursor activity in multiple sclerosis patients. (PubMed id 17086898)9 Weinstock-Guttman B....Ramanathan M. (Mult. Scler. 2006)
    584. Suppressed cellular alloimmune responses in HIV-exposed seronegative female sex workers. (PubMed id 16487242)9 Jennes W....Kestens L. (Clin. Exp. Immunol. 2006)
    585. Natural killer cell function is well preserved in asymptomatic human immunodeficiency virus type 2 (HIV-2) infection but similar to that of HIV-1 infection when CD4 T-cell counts fall. (PubMed id 16474159)9 Nuvor S.V....Jaye A. (J. Virol. 2006)
    586. Immolina, a high-molecular-weight polysaccharide fraction of Spirulina, enhances chemokine expression in human monocytic THP-1 cells. (PubMed id 16813506)9 Grzanna R....Frondoza C.G. (J Altern Complement Med 2006)
    587. Cytokines and chemokines in uveitis: is there a correlation with clinical phenotype? (PubMed id 17210978)9 Ooi K.G....Lightman S.L. (amp 2006)
    588. Intrathecal upregulation of granulocyte colony stimulating factor and its neuroprotective actions on motor neurons in amyotrophic lateral sclerosis. (PubMed id 16896315)9 Tanaka M....Kira J. (J. Neuropathol. Exp. Neurol. 2006)
    589. Identification of proteins differentially expressed in human monocytes exposed to Porphyromonas gingivalis and its purified components by high-throughput immunoblotting. (PubMed id 16428770)9 Zhou Q. and Amar S. (Infect. Immun. 2006)
    590. Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages. (PubMed id 16321392)9 Veillard N.R....Mach F. (Atherosclerosis 2006)
    591. TCR-independent cytokine stimulation induces non-MHC-restricted T cell activity and is negatively regulated by HLA class I. (PubMed id 16909431)9 von Geldern M....Falk C.S. (Eur. J. Immunol. 2006)
    592. HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. (PubMed id 16467198)9 Betts M.R....Koup R.A. (Blood 2006)
    593. Induction of chemokine receptor expression during early stages of T cell development. (PubMed id 16406125)9 Maerki S....Rolink A. (Immunol. Lett. 2006)
    594. Ethyl pyruvate exerts combined anti-inflammatory and anticoagulant effects on human monocytic cells. (PubMed id 17139374)9 van Zoelen M.A....van der Poll T. (Thromb. Haemost. 2006)
    595. Induction of multifunctional human immunodeficiency virus type 1 (HIV-1)-specific T cells capable of proliferation in healthy subjects by using a prime-boost regimen of DNA- and modified vaccinia virus Ankara-vectored vaccines expressing HIV-1 Gag coupled to CD8+ T-cell epitopes. (PubMed id 16641265)9 Goonetilleke N....McMichael A.J. (J. Virol. 2006)
    596. Cytokine profile in synovial fluid from patients with internal derangement of the temporomandibular joint: a preliminary study. (PubMed id 17082335)9 Matsumoto K....Otsuka K. (Dentomaxillofac Radiol 2006)
    597. Extracellular HIV-1 Nef increases migration of monocytes. (PubMed id 16978607)9 Lehmann M.H....Erfle V. (Exp. Cell Res. 2006)
    598. [Bone disease in multiple myeloma and its mechanism]. (PubMed id 16582506)9 Abe M. (Clin Calcium 2006)
    599. The molecular cloning and functional expression of the dog CCR5. (PubMed id 16806494)9 Mosley M....Holbrook M. (Vet. Immunol. Immunopathol. 2006)
    600. Immunohistochemical evidence of a cytokine and chemokine network in three patients with Erdheim-Chester disease: implications for pathogenesis. (PubMed id 17133532)9 Stoppacciaro A....Sabbadini M.G. (Arthritis Rheum. 2006)
    601. Lentivirus vectors expressing short hairpin RNAs against the U3-overlapping region of HIV nef inhibit HIV replication and infectivity in primary macrophages. (PubMed id 16857988)9 Yamamoto T....Tsunetsugu-Yokota Y. (Blood 2006)
    602. TWEAK is a novel arthritogenic mediator. (PubMed id 16888023)9 Perper S.J....Hess H. (J. Immunol. 2006)
    603. Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers. (PubMed id 16467191)9 Springael J.Y....Parmentier M. (Mol. Pharmacol. 2006)
    604. Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-gamma- and CD40L-mediated costimulation. (PubMed id 16330536)9 Verreck F.A....Ottenhoff T.H. (J. Leukoc. Biol. 2006)
    605. [Assessment of a microarray of solid-phase antibodies to the study of chemokines secreted by the chorioamniotic membrane]. (PubMed id 17539322)9 GA^mez LA^pez N.Y....Vadillo Ortega F. (Ginecol Obstet Mex 2006)
    606. Control of cytokine gene expression by PG101, a water-soluble extract prepared from Lentinus lepideus. (PubMed id 16344041)9 Choi J.J....Kim S. (Biochem. Biophys. Res. Commun. 2006)
    607. Strain differences influence murine pulmonary responses to Stachybotrys chartarum. (PubMed id 16690987)9 Rosenblum Lichtenstein J.H....Brain J.D. (Am. J. Respir. Cell Mol. Biol. 2006)
    608. Cytokine assay of the epidural space lavage in patients with lumbar intervertebral disk herniation and radiculopathy. (PubMed id 16778661)9 Scuderi G.J....Hallab N. (amp 2006)
    609. Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. (PubMed id 16782408)9 Gounni Abdelilah S....Lamkhioued B. (Clin. Immunol. 2006)
    610. The Src kinase Lyn is required for CCR5 signaling in response to MIP-1beta and R5 HIV-1 gp120 in human macrophages. (PubMed id 16621960)9 Tomkowicz B....Collman R.G. (Blood 2006)
    611. Cytokine mapping of sera from women with preeclampsia and normal pregnancies. (PubMed id 16388854)9 Jonsson Y....Ekerfelt C. (J. Reprod. Immunol. 2006)
    612. Inhibition by triptolide of chemokine, proinflammatory cytokine, and adhesion molecule expression induced by lipopolysaccharide in corneal fibroblasts. (PubMed id 16936090)9 Lu Y....Nishida T. (amp 2006)
    613. Cytokine expression profile over time in severely burned pediatric patients. (PubMed id 16783192)9 Finnerty C.C....Jeschke M.G. (Shock 2006)
    614. CSF cytokine and chemokine profiles in acute disseminated encephalomyelitis. (PubMed id 16697050)9 Ishizu T....Kira J. (J. Neuroimmunol. 2006)
    615. Mucosal innate immune factors in the female genital tract are associated with vaginal HIV-1 shedding independent of plasma viral load. (PubMed id 16910835)9 Cummins J.E....Dezzutti C.S. (AIDS Res. Hum. Retroviruses 2006)
    616. Involvement of CCR5 in the passage of Th1-type cells across the blood-retina barrier in experimental autoimmune uveitis. (PubMed id 16365158)9 Crane I.J....Forrester J.V. (J. Leukoc. Biol. 2006)
    617. Effect of clarithromycin on cytokines and chemokines in children with an acute exacerbation of recurrent wheezing: a double-blind, randomized, placebo-controlled trial. (PubMed id 17069099)9 Fonseca-Aten M....Hardy R.D. (amp 2006)
    618. Functional and genomic changes induced by alveolar transmigration in human neutrophils. (PubMed id 16861384)9 Coldren C.D....Geraci M.W. (Am. J. Physiol. Lung Cell Mol. Physiol. 2006)
    619. Signaling events involved in cytokine and chemokine production induced by secretory phospholipase A2 in human lung macrophages. (PubMed id 16761312)9 Granata F....Triggiani M. (Eur. J. Immunol. 2006)
    620. Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation. (PubMed id 16713992)9 Liu Q....Cao X. (Biochem. Biophys. Res. Commun. 2006)
    621. Monocyte chemotactic protein-1 is a potential player in the negative cross-talk between adipose tissue and skeletal muscle. (PubMed id 16439461)9 Sell H....Eckel J. (Endocrinology 2006)
    622. CCR5 expression and duration of high risk sexual activity among HIV-seronegative men who have sex with men. (PubMed id 16954729)9 Thomas S.M....Marmor M. (AIDS 2006)
    623. Polymorphonuclear leucocytes selectively produce anti-inflammatory interleukin-1 receptor antagonist and chemokines, but fail to produce pro-inflammatory mediators. (PubMed id 17067311)9 SchrAPder A.K....Rink L. (Immunology 2006)
    624. Immunomonitoring of renal transplant recipients in the early posttransplant period by sequential analysis of chemokine and chemokine receptor gene expression in peripheral blood mononuclear cells. (PubMed id 15848520)9 Dalton R.S....Howell W.M. (Transplant. Proc. 2005)
    625. Molecular cloning and radioligand binding characterization of the chemokine receptor CCR5 from rhesus macaque and human. (PubMed id 16298345)9 Napier C....Holbrook M. (Biochem. Pharmacol. 2005)
    626. Simultaneous detection of multiple cytokines and chemokines from nonhuman primates using luminex technology. (PubMed id 15896800)9 Giavedoni L.D. (J. Immunol. Methods 2005)
    627. Hsp70-like protein 1 fusion protein enhances induction of carcinoembryonic antigen-specific CD8+ CTL response by dendritic cell vaccine. (PubMed id 15930317)9 Wu Y.... Cao X. (Cancer Res. 2005)
    628. Delayed leukocytosis and cytokine response to high-force eccentric exercise. (PubMed id 16286856)9 Paulsen G....Raastad T. (Med Sci Sports Exerc 2005)
    629. Cytokine profiling for prediction of symptomatic radiation-induced lung injury. (PubMed id 16115739)9 Hart J.P....Anscher M.S. (Int. J. Radiat. Oncol. Biol. Phys. 2005)
    630. Innate immune responses in Lyme borreliosis: enhanced tumour necrosis factor-alpha and interleukin-12 in asymptomatic individuals in response to live spirochetes. (PubMed id 15958074)9 SjAPwall J....Ekerfelt C. (Clin. Exp. Immunol. 2005)
    631. Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion. (PubMed id 16103156)9 Medin C.L....Rothman A.L. (J. Virol. 2005)
    632. Influence of the R22H variant of macrophage inflammatory protein 1beta/Lag-1 in HIV-1 survival. (PubMed id 15867499)9 Capoulade-MActay C....Theodorou I. (AIDS 2005)
    633. Absence of favourable changes in circulating levels of interleukin-16 or beta-chemokine concentration following structured intermittent interruption treatment of chronic human immunodeficiency virus infection. (PubMed id 15649305)9 Montes de Oca Arjona M....GirA^n-GonzA!lez J.A. (Clin. Microbiol. Infect. 2005)
    634. Up-regulation of interleukin-8, interleukin-10, monocyte chemotactic protein-1, and monocyte chemotactic protein-3 in peripheral blood monocytes in stable lung transplant recipients: are immunosuppression regimens working? (PubMed id 15729163)9 Hodge G....Holmes M. (Transplantation 2005)
    635. Transgenic mouse expressing human CCR5 as a model for in vivo assessments of human selective CCR5 antagonists. (PubMed id 16076464)9 Saita Y....Shimizu Y. (Eur. J. Pharmacol. 2005)
    636. Astrocytes produce dendritic cell-attracting chemokines in vitro and in multiple sclerosis lesions. (PubMed id 16106219)9 Ambrosini E....Coccia E.M. (J. Neuropathol. Exp. Neurol. 2005)
    637. Expression of chemokine receptors CCR5 and CXCR4 on CD4+ T cells and plasma chemokine levels during treatment of active tuberculosis in HIV-1-coinfected patients. (PubMed id 15980685)9 Wolday D....Miedema F. (J. Acquir. Immune Defic. Syndr. 2005)
    638. Triptolide attenuates endotoxin- and staphylococcal exotoxin-induced T-cell proliferation and production of cytokines and chemokines. (PubMed id 15803859)9 Krakauer T....Young H.A. (Immunopharmacol Immunotoxicol 2005)
    639. Dendritic cells differentiated in the presence of IFN-{beta} and IL-3 are potent inducers of an antigen-specific CD8+ T cell response. (PubMed id 16037410)9 Breckpot K....Thielemans K. (J. Leukoc. Biol. 2005)
    640. Human gammadelta T cells from G-CSF-mobilized donors retain strong tumoricidal activity and produce immunomodulatory cytokines after clinical-scale isolation. (PubMed id 15614047)9 Otto M....Handgretinger R. (J. Immunother. 2005)
    641. Soluble chemokine CCR5 receptor is present in human plasma. (PubMed id 15585308)9 Tsimanis A....Bentwich Z. (Immunol. Lett. 2005)
    642. Secretion of cytokines and chemokines by polarized human epithelial cells from the female reproductive tract. (PubMed id 15734755)9 Fahey J.V....Wira C.R. (Hum. Reprod. 2005)
    643. Chemokines in human colorectal carcinoma. (PubMed id 16101183)9 Baier P.K....Hopt U.T. (Anticancer Res. 2005)
    644. Macrophage inflammatory protein 1alpha inhibits postentry steps of human immunodeficiency virus type 1 infection via suppression of intracellular cyclic AMP. (PubMed id 15827177)9 Amella C.A....Schmidtmayerova H. (J. Virol. 2005)
    645. Differential expression of chemokines and chemokine receptors in inflammatory periapical diseases. (PubMed id 16101967)9 Silva T.A....Cunha F.Q. (Oral Microbiol. Immunol. 2005)
    646. Not all tetramer binding CD8+ T cells can produce cytokines and chemokines involved in the effector functions of virus-specific CD8+ T lymphocytes in HIV-1 infected children. (PubMed id 15742158)9 Scott-Algara D....Riviere Y. (J. Clin. Immunol. 2005)
    647. Decreased IgG production but increased MIP-1beta expression in collagen-induced arthritis in C-C chemokine receptor 5-deficient mice. (PubMed id 15967376)9 Bao L....Lindgren J.U. (Cytokine 2005)
    648. Bacillus anthracis edema toxin inhibits Staphylococcus aureus enterotoxin B effects in vitro: a potential protein therapeutic? (PubMed id 16177395)9 Krakauer T....Stiles B.G. (Infect. Immun. 2005)
    649. Th1 shift in CIDP versus Th2 shift in vasculitic neuropathy in CSF. (PubMed id 15607214)9 Mei F.J....Kira J. (J. Neurol. Sci. 2005)
    650. Functional expression of beta-chemokine receptors in osteoblasts: role of regulated upon activation, normal T cell expressed and secreted (RANTES) in osteoblasts and regulation of its secretion by osteoblasts and osteoclasts. (PubMed id 15718270)9 Yano S....Chattopadhyay N. (Endocrinology 2005)
    651. Chemokines and their receptors in the pathogenesis of allergic asthma: progress and perspective. (PubMed id 15591886)9 Bisset L.R. and Schmid-Grendelmeier P. (Curr Opin Pulm Med 2005)
    652. CCL3 (MIP-1alpha) induces in vitro migration of GM-CSF-primed human neutrophils via CCR5-dependent activation of ERK 1/2. (PubMed id 15567066)9 Ottonello L....Dallegri F. (Cell. Signal. 2005)
    653. Myeloma bone disease. (PubMed id 16188625)9 Sezer O. (Hematology 2005)
    654. Transcriptomic and proteomic patterns of systemic inflammation in on-pump and off-pump coronary artery bypass grafting. (PubMed id 16275880)9 Tomic V....Bauer M. (Circulation 2005)
    655. Mucosal alloimmunization elicits T-cell proliferation, CC chemokines, CCR5 antibodies and inhibition of simian immunodeficiency virus infectivity. (PubMed id 16033970)9 Bergmeier L.A....Lehner T. (J. Gen. Virol. 2005)
    656. Novel aspects of osteoclast activation and osteoblast inhibition in myeloma bone disease. (PubMed id 16216218)9 Heider U....Sezer O. (Biochem. Biophys. Res. Commun. 2005)
    657. Impaired FcepsilonRI-dependent gene expression and defective eicosanoid and cytokine production as a consequence of Fyn deficiency in mast cells. (PubMed id 16301670)9 Gomez G....Rivera J. (J. Immunol. 2005)
    658. Fas signal links innate and adaptive immunity by promoting dendritic-cell secretion of CC and CXC chemokines. (PubMed id 15941911)9 Guo Z....Cao X. (Blood 2005)
    659. Virus overrides the propensity of human CD40L-activated plasmacytoid dendritic cells to produce Th2 mediators through synergistic induction of IFN-{gamma} and Th1 chemokine production. (PubMed id 16081597)9 Bendriss-Vermare N....BriA"re F. (J. Leukoc. Biol. 2005)
    660. Patterns of cytokine production in human immunodeficiency virus type 1 (HIV-1)-specific human CD8+ T cells after stimulation with HIV-1-infected CD4+ T cells. (PubMed id 16160181)9 Fujiwara M....Takiguchi M. (J. Virol. 2005)
    661. Elimination of innate immune responses and liver inflammation by PEGylation of adenoviral vectors and methylprednisolone. (PubMed id 16390275)9 De Geest B....Collen D. (Hum. Gene Ther. 2005)
    662. Involvement of Th1 cells and heat shock protein 60 in the pathogenesis of intestinal Behcet's disease. (PubMed id 15654837)9 Imamura Y....Suzuki N. (Clin. Exp. Immunol. 2005)
    663. Distinct profiles of SjAPgren's syndrome patients with ectopic salivary gland germinal centers revealed by serum cytokines and BAFF. (PubMed id 16126006)9 Szodoray P....Centola M. (Clin. Immunol. 2005)
    664. The cotton rat provides a useful small-animal model for the study of influenza virus pathogenesis. (PubMed id 16186238)9 Ottolini M.G....Prince G.A. (J. Gen. Virol. 2005)
    665. Spirodiketopiperazine-based CCR5 inhibitor which preserves CC-chemokine/CCR5 interactions and exerts potent activity against R5 human immunodeficiency virus type 1 in vitro. (PubMed id 15280474)9 Maeda K....Mitsuya H. (J. Virol. 2004)
    666. Leprosy patients with lepromatous disease have an up-regulated IL-8 response that is unlinked to TNF-alpha responses. (PubMed id 15217317)9 Hasan Z....Hussain R. (Int. J. Lepr. Other Mycobact. Dis. 2004)
    667. Novel heat shock protein Hsp70L1 activates dendritic cells and acts as a Th1 polarizing adjuvant. (PubMed id 14592822)9 Wan T.... Cao X. (Blood 2004)
    668. Induction of C chemokine XCL1 (lymphotactin/single C motif-1 alpha/activation-induced, T cell-derived and chemokine-related cytokine) expression by HIV-1 Tat protein. (PubMed id 14734774)9 Kim B.O....He J.J. (J. Immunol. 2004)
    669. New molecular markers of early and progressive CJD brain infection. (PubMed id 15660413)9 Lu Z.Y....Manuelidis L. (J. Cell. Biochem. 2004)
    670. Cytokine networks are pre-activated in T cells from HIV-infected patients on HAART and are under the control of cAMP. (PubMed id 15075533)9 Johansson C.C....TaskAcn K. (AIDS 2004)
    671. Circulating cytokines in primary SjAPgren's syndrome determined by a multiplex cytokine array system. (PubMed id 15182255)9 Szodoray P....Jonsson R. (Scand. J. Immunol. 2004)
    672. The chemokine receptor, CCR5. (PubMed id 14592532)9 Mueller A. and Strange P.G. (amp 2004)
    673. Impairment of beta chemokine and cytokine production in patients with HIV related Pneumocystis jerovici pneumonia. (PubMed id 14985564)9 IsraAl-Biet D....Cadranel J. (Thorax 2004)
    674. Vaccination in humans generates broad T cell cytokine responses. (PubMed id 15494483)9 De Rosa S.C....Roederer M. (J. Immunol. 2004)
    675. Expression of chemokines by human fetal microglia after treatment with the human immunodeficiency virus type 1 protein Tat. (PubMed id 15204927)9 D'Aversa T.G....Berman J.W. (J. Neurovirol. 2004)
    676. Advanced glycation end products induce secretion of chemokines and apoptosis in human first trimester trophoblasts. (PubMed id 15243005)9 Konishi H....Hiramatsu Y. (Hum. Reprod. 2004)
    677. Oxidative stress - a link between endothelial injury, coagulation activation, and atherosclerosis in haemodialysis patients. (PubMed id 14726627)9 Pawlak K....MyA9liwiec M. (Am. J. Nephrol. 2004)
    678. Adenine nucleotides inhibit cytokine generation by human mast cells through a Gs-coupled receptor. (PubMed id 15585881)9 Feng C....Boyce J.A. (J. Immunol. 2004)
    679. Yin zi huang, an injectable multicomponent chinese herbal medicine, is a potent inhibitor of T-cell activation. (PubMed id 15253857)9 Chen X....Howard O.M. (J Altern Complement Med 2004)
    680. The scope and activation mechanisms of chemokine gene expression in primary astrocytes following infection with Theiler's virus. (PubMed id 15020072)9 Palma J.P. and Kim B.S. (J. Neuroimmunol. 2004)
    681. Cytokine and chemokine expression profiles of maturing dendritic cells using multiprotein platform arrays. (PubMed id 14687583)9 Nagorsen D....Panelli M.C. (Cytokine 2004)
    682. Trafficking of natural killer cells. (PubMed id 15354873)9 Morris M.A. and Ley K. (Curr. Mol. Med. 2004)
    683. Optimizing anti-TNF treatment in inflammatory bowel disease. (PubMed id 15168370)9 Rutgeerts P....Vermeire S. (Gastroenterology 2004)
    684. Concentrations of macrophage inflammatory proteins MIP-1alpha and MIP-1beta and interleukin 8 (il-8) in lyme borreliosis. (PubMed id 15597225)9 Grygorczuk S....Hermanowska-Szpakowicz T. (Infection 2004)
    685. Hypoxia selectively inhibits monocyte chemoattractant protein-1 production by macrophages. (PubMed id 14734750)9 Bosco M.C....Varesio L. (J. Immunol. 2004)
    686. Chemokine receptor 5 is dispensable for innate and adaptive immune responses to Listeria monocytogenes infection. (PubMed id 14742553)9 Zhong M.X....Serbina N.V. (Infect. Immun. 2004)
    687. New CCR5 variants associated with reduced HIV coreceptor function in southeast Asia. (PubMed id 15577536)9 Capoulade-Metay C.... Theodorou I. (AIDS 2004)
    688. Interaction of endotoxins with Toll-like receptor 4 correlates with their endotoxic potential and may explain the proinflammatory effect of Brucella spp. LPS. (PubMed id 15339879)9 DueA+as A.I....GarcA-a-RodrA-guez C. (Int. Immunol. 2004)
    689. Diffuse large B-cell lymphoma presenting with hypercalcemia and multiple osteolysis. (PubMed id 15101731)9 Matsuhashi Y....Ishida T. (amp 2004)
    690. Identification of chemokines important for leukocyte recruitment to the human endometrium at the times of embryo implantation and menstruation. (PubMed id 15579772)9 Jones R.L....Salamonsen L.A. (J. Clin. Endocrinol. Metab. 2004)
    691. The inflammatory side of human chondrocytes unveiled by antibody microarrays. (PubMed id 15381094)9 De Ceuninck F....Anract P. (Biochem. Biophys. Res. Commun. 2004)
    692. Mycobacterium tuberculosis-induced CXCR4 and chemokine expression leads to preferential X4 HIV-1 replication in human macrophages. (PubMed id 15128813)9 Hoshino Y....Weiden M. (J. Immunol. 2004)
    693. Characterization of a highly inducible novel CC chemokine from differentiated rainbow trout (Oncorhynchus mykiss) macrophages. (PubMed id 15503008)9 Mackenzie S....Goetz F.W. (Immunogenetics 2004)
    694. Transcriptional analysis of human peripheral blood mononuclear cells after influenza immunization. (PubMed id 15364265)9 Diaz-Mitoma F....Giulivi A. (J. Clin. Virol. 2004)
    695. Intratumoral expression of MIP-1beta induces antitumor responses in a pre-established tumor model through chemoattracting T cells and NK cells. (PubMed id 16219168)9 Luo X....Cao X. (amp 2004)
    696. Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. (PubMed id 14736420)9 Copeland S....Remick D. (J. Immunol. Methods 2004)
    697. Lack of good correlation of serum CC-chemokine levels with human immunodeficiency virus-1 disease stage and response to treatment. (PubMed id 15122175)9 Ye P....Kirschner D.E. (J. Lab. Clin. Med. 2004)
    698. HIV co-receptors as targets for antiviral therapy. (PubMed id 15134547)9 Schols D. (Curr Top Med Chem 2004)
    699. Elevated expression of GM3 in receptor-bearing targets confers resistance to human immunodeficiency virus type 1 fusion. (PubMed id 15220409)9 Rawat S.S....Puri A. (J. Virol. 2004)
    700. CC-chemokine receptor 5 (CCR5) in hepatitis C--at the crossroads of the antiviral immune response? (PubMed id 15128728)9 Ahlenstiel G....Spengler U. (J. Antimicrob. Chemother. 2004)
    701. Hydroxymethylglutaryl coenzyme a reductase inhibitors down-regulate chemokines and chemokine receptors in patients with coronary artery disease. (PubMed id 12742282)9 Waehre T....Aukrust P. (J. Am. Coll. Cardiol. 2003)
    702. Inhibition of chemokine receptor function by membrane cholesterol oxidation. (PubMed id 14597406)9 Nguyen D.H. and Taub D.D. (Exp. Cell Res. 2003)
    703. Genotypes of CCR2 and CCR5 chemokine receptors in human myasthenia gravis. (PubMed id 14533004)9 Zhao X....Ghaderi M. (Int. J. Mol. Med. 2003)
    704. Heat-induced superaggregation of amphotericin B attenuates its ability to induce cytokine and chemokine production in the human monocytic cell line THP-1. (PubMed id 12562711)9 Rogers P.D....Jacob M. (J. Antimicrob. Chemother. 2003)
    705. Chemokine bioactivity of RANTES is elevated in the sera of infertile women with past Chlamydia trachomatis infection. (PubMed id 12797523)9 Shibahara H....Sato I. (Am. J. Reprod. Immunol. 2003)
    706. Treatment with an anti-CD14 monoclonal antibody delays and inhibits lipopolysaccharide-induced gene expression in humans in vivo. (PubMed id 12757265)9 Spek C.A....Reitsma P.H. (J. Clin. Immunol. 2003)
    707. Aberrated levels of cerebrospinal fluid chemokines in Guillain-BarrAc syndrome and chronic inflammatory demyelinating polyradiculoneuropathy. (PubMed id 12959218)9 Press R....Link H. (J. Clin. Immunol. 2003)
    708. Changes in the levels of chemokines and cytokines in the placentas of women with Plasmodium falciparum malaria. (PubMed id 14513430)9 Suguitan A.L....Taylor D.W. (J. Infect. Dis. 2003)
    709. Membrane incorporation of 22-hydroxycholesterol inhibits chemokine receptor activity. (PubMed id 12706121)9 Nguyen D.H. and Taub D.D. (Exp. Cell Res. 2003)
    710. Characterization of drug-specific T cells in lamotrigine hypersensitivity. (PubMed id 12789244)9 Naisbitt D.J....Park B.K. (J. Allergy Clin. Immunol. 2003)
    711. Cutting edge: increased NK cell activity in HIV-1-exposed but uninfected Vietnamese intravascular drug users. (PubMed id 14634071)9 Scott-Algara D....Pancino G. (J. Immunol. 2003)
    712. Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2. (PubMed id 12837756)9 Alvarez Arias D....Peiper S.C. (J. Biol. Chem. 2003)
    713. Human neuronal cells (NT2-N) express functional substance P and neurokinin-1 receptor coupled to MIP-1 beta expression. (PubMed id 12548712)9 Li Y....Ho W. (J. Neurosci. Res. 2003)
    714. Chemokine receptor expression in human endometrium. (PubMed id 12606476)9 Mulayim N....Arici A. (Biol. Reprod. 2003)
    715. Smooth and rough lipopolysaccharide phenotypes of Brucella induce different intracellular trafficking and cytokine/chemokine release in human monocytes. (PubMed id 12960272)9 Rittig M.G....Dornand J. (J. Leukoc. Biol. 2003)
    716. Morphine enhances HIV infection of neonatal macrophages. (PubMed id 12736382)9 Li Y....Ho W.Z. (Pediatr. Res. 2003)
    717. Cellular human immunodeficiency virus (HIV)-protective factors: a comparison of HIV-exposed seronegative female sex workers and female blood donors in Abidjan, CA'te d'Ivoire. (PubMed id 12552445)9 Jennes W....Kestens L. (J. Infect. Dis. 2003)
    718. Amyloid peptide-induced cytokine and chemokine expression in THP-1 monocytes is blocked by small inhibitory RNA duplexes for early growth response-1 messenger RNA. (PubMed id 12734378)9 Giri R.K....Kalra V.K. (J. Immunol. 2003)
    719. New insights in myeloma-induced osteolysis. (PubMed id 14565645)9 BarillAc-Nion S. and Bataille R. (amp 2003)
    720. [Serum and cerebrospinal fluid concentration of inflammatory proteins MIP-1-alpha and MIP-1-beta and of interleukin 8 in the course of borreliosis]. (PubMed id 12910831)9 Grygorczuk S....Hermanowska-Szpakowicz T. (Neurol. Neurochir. Pol. 2003)
    721. Current perspectives on cytokines for anti-retroviral therapy in AIDS related B-cell lymphomas. (PubMed id 12769791)9 Sharma V. (Curr Drug Targets Infect Disord 2003)
    722. Evaluation of SDF-1/CXCR4-induced Ca2+ signaling by fluorometric imaging plate reader (FLIPR) and flow cytometry. (PubMed id 12500303)9 Princen K....Schols D. (Cytometry A 2003)
    723. Avocado/soybean unsaponifiables increase aggrecan synthesis and reduce catabolic and proinflammatory mediator production by human osteoarthritic chondrocytes. (PubMed id 12913942)9 Henrotin Y.E....Reginster J.Y. (J. Rheumatol. 2003)
    724. Pneumolysin-dependent and -independent gene expression identified by cDNA microarray analysis of THP-1 human mononuclear cells stimulated by Streptococcus pneumoniae. (PubMed id 12654830)9 Rogers P.D....McDaniel L.S. (Infect. Immun. 2003)
    725. Delayed leukocytosis after hard strength and endurance exercise: aspects of regulatory mechanisms. (PubMed id 14667246)9 RisA...Benestad H.B. (BMC Physiol. 2003)
    726. Induction of protective immune responses against R5 human immunodeficiency virus type 1 (HIV-1) infection in hu-PBL-SCID mice by intrasplenic immunization with HIV-1-pulsed dendritic cells: possible involvement of a novel factor of human CD4(+) T-cell origin. (PubMed id 12885891)9 Yoshida A....Tanaka Y. (J. Virol. 2003)
    727. An association of autoantibody status and serum cytokine levels in type 1 diabetes. (PubMed id 12716743)9 Hanifi-Moghaddam P....Kolb H. (Diabetes 2003)
    728. Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor. (PubMed id 12689930)9 Selvaraj S.K....Kalra V.K. (Blood 2003)
    729. In vivo proteomic analysis of cytokine expression in laser capture-microdissected urothelial cells of obstructed ureteropelvic junction procured by laparoscopic dismembered pyeloplasty. (PubMed id 12885361)9 Tadros Y....Abdel-Mageed A.B. (J. Endourol. 2003)
    730. HIV-1-suppressive factors are secreted by CD4+ T cells during primary immune responses. (PubMed id 14657379)9 Abdelwahab S.F....Lewis G.K. (Proc. Natl. Acad. Sci. U.S.A. 2003)
    731. Alternative conformations of HIV-1 V3 loops mimic beta hairpins in chemokines, suggesting a mechanism for coreceptor selectivity. (PubMed id 12575942)9 Sharon M....Anglister J. (Structure 2003)
    732. HIV type 1 infection alters cytokine mRNA expression in thymus. (PubMed id 12581511)9 Koka P.S....Zack J.A. (AIDS Res. Hum. Retroviruses 2003)
    733. Interleukin-7-dependent production of RANTES that correlates with human immunodeficiency virus disease progression. (PubMed id 12634395)9 Llano A....EstAc J.A. (J. Virol. 2003)
    734. In situ study of chemokine and chemokine-receptor expression in Kaposi sarcoma. (PubMed id 14501286)9 Uccini S....Ruco L. (Am J Dermatopathol 2003)
    735. Upregulation of expression of the chemokine receptor CCR5 by hydrogen peroxide in human monocytes. (PubMed id 12745546)9 Lehoux G....Rola-Pleszczynski M. (Mediators Inflamm. 2003)
    736. Potential interaction between CCR1 and its ligand, CCL3, induced by endogenously produced interleukin-1 in human hepatomas. (PubMed id 12651617)9 Lu P....Mukaida N. (Am. J. Pathol. 2003)
    737. Infection of human mononuclear phagocytes and macrophage-like THP1 cells with Leishmania donovani results in modulation of expression of a subset of chemokines and a chemokine receptor. (PubMed id 12662300)9 Dasgupta B....Roy S. (Scand. J. Immunol. 2003)
    738. Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways. (PubMed id 12960231)9 Lee C....Collman R.G. (J. Leukoc. Biol. 2003)
    739. Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gamma delta T lymphocytes. (PubMed id 12355447)9 Dagna L....Ferrarini M. (Eur. J. Immunol. 2002)
    740. Chemokine receptor CCR5: polymorphism at protein level. (PubMed id 12163044)9 Suzuki S....Chuang R.Y. (Biochem. Biophys. Res. Commun. 2002)
    741. Chemokines as natural HIV antagonists. (PubMed id 12462390)9 Verani A. and Lusso P. (Curr. Mol. Med. 2002)
    742. IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling. (PubMed id 11884467)9 Zhu Z....Elias J.A. (J. Immunol. 2002)
    743. Improvement of interleukin 2 production, clonogenic capability and restoration of stromal cell function in human immunodeficiency virus-type-1 patients after highly active antiretroviral therapy. (PubMed id 12181060)9 IsgrA^ A....Aiuti F. (Br. J. Haematol. 2002)
    744. Non-peptidic chemokine receptors antagonists as emerging anti-HIV agents. (PubMed id 12420752)9 Scozzafava A....Supuran C.T. (J Enzyme Inhib Med Chem 2002)
    745. Different chemokines are expressed in human arthritic bone biopsies: IFN-gamma and IL-6 differently modulate IL-8, MCP-1 and rantes production by arthritic osteoblasts. (PubMed id 12550108)9 Lisignoli G....Facchini A. (Cytokine 2002)
    746. Multiplexed protein profiling on microarrays by rolling-circle amplification. (PubMed id 11923841)9 Schweitzer B....Kingsmore S.F. (Nat. Biotechnol. 2002)
    747. Chemotaxis of human tonsil B lymphocytes to CC chemokine receptor (CCR) 1, CCR2 and CCR4 ligands is restricted to non-germinal center cells. (PubMed id 12147625)9 Corcione A....Pistoia V. (Int. Immunol. 2002)
    748. Peripheral blood mononuclear cells from infants hospitalized because of respiratory syncytial virus infection express T helper-1 and T helper-2 cytokines and CC chemokine messenger RNA. (PubMed id 11992272)9 Tripp R.A....Anderson L.J. (J. Infect. Dis. 2002)
    749. Expression patterns of cytokines and chemokines genes in human hepatoma cells. (PubMed id 12402381)9 Shin E.C....Park J.H. (Yonsei Med. J. 2002)
    750. CD40-activated macrophages become highly susceptible to X4 strains of human immunodeficiency virus type 1. (PubMed id 11839143)9 Bakri Y....Benjouad A. (AIDS Res. Hum. Retroviruses 2002)
    751. Adhesion of B cell lines to endothelial cells from human lymphoid tissue modulates tyrosine phosphorylation and endothelial cell activation. (PubMed id 12421971)9 Reyes L.I....Rosemblatt M. (J. Immunol. 2002)
    752. CXCR4/CCR5 down-modulation and chemotaxis are regulated by the proteasome pathway. (PubMed id 11877445)9 Fernandis A.Z....Ganju R.K. (J. Biol. Chem. 2002)
    753. CC chemokine receptor 5 and interleukin-1 receptor antagonist gene polymorphisms in patients with primary SjAPgren's syndrome. (PubMed id 12412204)9 Petrek M....BosA!k V. (Clin. Exp. Rheumatol. 2002)
    754. CCR5 genotype and plasma beta-chemokine concentration of Brazilian HIV-infected individuals. (PubMed id 12426633)9 Mikawa A.Y....Costa P.I. (Braz. J. Med. Biol. Res. 2002)
    755. Effects of Shuanghuanglian and Qingkailing, two multi-components of traditional Chinese medicinal preparations, on human leukocyte function. (PubMed id 12269401)9 Chen X....Krakauer T. (Life Sci. 2002)
    756. Gene copy number regulates the production of the human chemokine CCL3-L1. (PubMed id 12355456)9 Townson J.R....Nibbs R.J. (Eur. J. Immunol. 2002)
    757. Kinetics of gene induction after FcepsilonRI ligation of atopic monocytes identified by suppression subtractive hybridization. (PubMed id 12444121)9 Von Bubnoff D....De La Salle H. (J. Immunol. 2002)
    758. Regulation of CC chemokine receptor 5 and CD4 expression and human immunodeficiency virus type 1 replication in human macrophages and microglia by T helper type 2 cytokines. (PubMed id 11920312)9 Wang J....Gabuzda D. (J. Infect. Dis. 2002)
    759. Interactions of opioid and chemokine receptors: oligomerization of mu, kappa, and delta with CCR5 on immune cells. (PubMed id 12413885)9 Suzuki S.... Chuang R.Y. (Exp. Cell Res. 2002)
    760. The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways. (PubMed id 12387745)9 Dejardin E....Green D.R. (Immunity 2002)
    761. Cytokine and adhesion molecule expression in primary human endothelial cells stimulated with fever-range hyperthermia. (PubMed id 12537753)9 Shah A....Evans S.S. (Int J Hyperthermia 2002)
    762. Expression of beta-chemokines and chemokine receptors in human fetal astrocyte and microglial co-cultures: potential role of chemokines in the developing CNS. (PubMed id 11746784)9 Rezaie P....Male D.K. (Glia 2002)
    763. Expression, hormonal regulation, and cyclic variation of chemokines in the rat ovary: key determinants of the intraovarian residence of representatives of the white blood cell series. (PubMed id 11861498)9 Wong K.H....Adashi E.Y. (Endocrinology 2002)
    764. Selective suppression of neutrophil accumulation in ongoing pulmonary inflammation by systemic inhibition of p38 mitogen-activated protein kinase. (PubMed id 12391245)9 Nick J.A....Worthen G.S. (J. Immunol. 2002)
    765. Reduced expression of Th1-associated chemokine receptors on peripheral blood lymphocytes at diagnosis of type 1 diabetes. (PubMed id 12145160)9 Lohmann T....Kiess W. (Diabetes 2002)
    766. HIV and chemokines: implications for therapy and vaccine. (PubMed id 11983255)9 Lusso P. (Vaccine 2002)
    767. Characterization of the phenotypic and lymphokine profile associated with strong CD8+ anti-HIV-1 suppressor activity (CASA). (PubMed id 11882045)9 Wilkinson J....Cooper D.A. (Clin. Exp. Immunol. 2002)
    768. Morphine regulates gene expression of alpha- and beta-chemokines and their receptors on astroglial cells via the opioid mu receptor. (PubMed id 12244149)9 Mahajan S.D....Nair M.P. (J. Immunol. 2002)
    769. The effect of X4 and R5 HIV-1 on C, C-C, and C-X-C chemokines during the early stages of infection in human PBMCs. (PubMed id 11878903)9 Wetzel M.A....Rogers T.J. (Virology 2002)
    770. Proinflammatory response during Ebola virus infection of primate models: possible involvement of the tumor necrosis factor receptor superfamily. (PubMed id 11803049)9 Hensley L.E....Geisbert T.W. (Immunol. Lett. 2002)
    771. Comprehensive gene expression profile of human activated T(h)1- and T(h)2-polarized cells. (PubMed id 11222506)9 Nagai S....Matsushima K. (Int. Immunol. 2001)
    772. A cSNP map and database for human chromosome 21. (PubMed id 11157793)9 Deutsch S....Scott H.S. (Genome Res. 2001)
    773. Role of Fc gamma receptors in triggering host cell activation and cytokine release by Borrelia burgdorferi. (PubMed id 11119532)9 Talkington J. and Nickell S.P. (Infect. Immun. 2001)
    774. Noncytolytic inhibition of X4 virus by bulk CD8(+) cells from human immunodeficiency virus type 1 (HIV-1)-infected persons and HIV-1-specific cytotoxic T lymphocytes is not mediated by beta-chemokines. (PubMed id 11483776)9 Geiben-Lynn R....Walker B.D. (J. Virol. 2001)
    775. A cofactor of tRNA synthetase, p43, is secreted to up-regulate proinflammatory genes. (PubMed id 11292833)9 Ko Y.G....Kim S. (J. Biol. Chem. 2001)
    776. Inhibition of endotoxin-induced macrophage chemokine production by vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide in vitro and in vivo. (PubMed id 11441105)9 Delgado M. and Ganea D. (J. Immunol. 2001)
    777. A distinct expression of CC chemokines by macrophages in nasopharyngeal carcinoma: implication for the intense tumor infiltration by T lymphocytes and macrophages. (PubMed id 11172294)9 Tang K.F....Hu H. (Hum. Pathol. 2001)
    778. Chemokines and their receptors in whiplash injury: elevated RANTES and CCR-5. (PubMed id 11506197)9 Kivioja J....Link H. (J. Clin. Immunol. 2001)
    779. Hantavirus infection induces the expression of RANTES and IP-10 without causing increased permeability in human lung microvascular endothelial cells. (PubMed id 11390609)9 Sundstrom J.B....Rollin P.E. (J. Virol. 2001)
    780. Binding of recombinant feline immunodeficiency virus surface glycoprotein to feline cells: role of CXCR4, cell-surface heparans, and an unidentified non-CXCR4 receptor. (PubMed id 11312323)9 de Parseval A. and Elder J.H. (J. Virol. 2001)
    781. Calcium signaling inhibits interleukin-12 production and activates CD83(+) dendritic cells that induce Th2 cell development. (PubMed id 11588047)9 Faries M.B....Czerniecki B.J. (Blood 2001)
    782. The flavonoid baicalin inhibits superantigen-induced inflammatory cytokines and chemokines. (PubMed id 11434925)9 Krakauer T....Young H.A. (FEBS Lett. 2001)
    783. Isolated human astrocytes are not susceptible to infection by M- and T-tropic HIV-1 strains despite functional expression of the chemokine receptors CCR5 and CXCR4. (PubMed id 11329179)9 Boutet A....Tardieu M. (Glia 2001)
    784. The presence of chemokine receptor (CCR5, CXCR3, CCR3)-positive cells and chemokine (MCP1, MIP-1alpha, MIP-1beta, IP-10)-positive cells in human periapical granulomas. (PubMed id 11683586)9 Kabashima H....Maeda K. (Cytokine 2001)
    785. The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells. (PubMed id 11553854)9 Kijowski J....Ratajczak M.Z. (Stem Cells 2001)
    786. Enhanced gene expression of chemokines and their corresponding receptors in mononuclear blood cells in chronic heart failure--modulatory effect of intravenous immunoglobulin. (PubMed id 11451272)9 DamAYs J.K....Aukrust P. (J. Am. Coll. Cardiol. 2001)
    787. Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4. (PubMed id 11509636)9 Smiley S.T....Hancock W.W. (J. Immunol. 2001)
    788. &quot;In vitro&quot; spontaneous production of B-chemokines by endocervical and endometrial short-term bioptic cultures. (PubMed id 11209849)9 Favia A....Pastore G. (New Microbiol. 2001)
    789. Up-regulation of IL-10R1 expression is required to render human neutrophils fully responsive to IL-10. (PubMed id 11490020)9 Crepaldi L....Cassatella M.A. (J. Immunol. 2001)
    790. A menstrual cycle pattern for cytokine levels exists in HIV-positive women: implication for HIV vaginal and plasma shedding. (PubMed id 11504986)9 Al-Harthi L....Landay A. (AIDS 2001)
    791. Chemokine receptor expression and function in CD4+ T lymphocytes with regulatory activity. (PubMed id 11145678)9 Sebastiani S....Cavani A. (J. Immunol. 2001)
    792. Inhibition of HIV infection by CXCR4 and CCR5 chemokine receptor antagonists. (PubMed id 11594685)9 De Clercq E. and Schols D. (amp 2001)
    793. Expression of mucosal cyto-chemokine mRNAs in patients with Helicobacter pylori infection. (PubMed id 11855151)9 Park S.M....Yoo B.C. (Korean J. Intern. Med. 2001)
    794. HIV-1 gp120 and chemokine activation of Pyk2 and mitogen-activated protein kinases in primary macrophages mediated by calcium-dependent, pertussis toxin-insensitive chemokine receptor signaling. (PubMed id 11698270)9 Del Corno M....Collman R.G. (Blood 2001)
    795. Changes in gene expression in macrophages infected with Mycobacterium tuberculosis: a combined transcriptomic and proteomic approach. (PubMed id 11576227)9 Ragno S....Colston M.J. (Immunology 2001)
    796. The role of C-C chemokines and their receptors in osteoarthritis. (PubMed id 11352237)9 Yuan G.H....Nishioka K. (Arthritis Rheum. 2001)
    797. Immunomodulatory effects of etanercept (TNFR:Fc) and its use in a patient with Crohn's disease. (PubMed id 11458980)9 Srivastava M.D. (Res. Commun. Mol. Pathol. Pharmacol. 2001)
    798. Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosis. (PubMed id 11532378)9 Sato S....Takehara K. (J. Dermatol. Sci. 2001)
    799. No difference in in vitro susceptibility to HIV type 1 between high-risk HIV-negative Ethiopian commercial sex workers and low-risk control subjects. (PubMed id 11282012)9 Messele T....Hamann D. (AIDS Res. Hum. Retroviruses 2001)
    800. Detection of elevated serum beta-chemokine levels in seronegative Chinese individuals exposed to human immunodeficiency virus type 1. (PubMed id 11438889)9 Shieh B....Li C. (Clin. Infect. Dis. 2001)
    801. Expression of beta chemokines in explants and trophoblasts from early and term human placentae. (PubMed id 11712758)9 Moussa M....Chaouat G. (Am. J. Reprod. Immunol. 2001)
    802. Enhanced maturation and functional capacity of monocyte-derived immature dendritic cells by the synthetic immunomodulator Murabutide. (PubMed id 11529939)9 Vidal V....Bahr G.M. (Immunology 2001)
    803. Histamine induces CD86 expression and chemokine production by human immature dendritic cells. (PubMed id 11342615)9 Caron G....Jeannin P. (J. Immunol. 2001)
    804. Human neutrophils produce macrophage inhibitory protein-1beta but not type i interferons in response to viral stimulation. (PubMed id 11359655)9 von der Ohe M....Rink L. (amp 2001)
    805. mRNA expression of cytokines and chemokines in the normal gastric surface mucous epithelial cell line GSM06 during bacterial infection with Helicobacter felis. (PubMed id 11595476)9 Debreceni A....Chiba T. (J. Physiol. Paris 2001)
    806. Molecular and cellular mediators of interleukin-1-dependent acute inflammatory arthritis. (PubMed id 11229476)9 Lawlor K.E....Wicks I.P. (Arthritis Rheum. 2001)
    807. Expression and regulation of chemokine receptors in human natural killer cells. (PubMed id 11154210)9 Inngjerdingen M....Maghazachi A.A. (Blood 2001)
    808. Local inflammatory responses following bronchial endotoxin instillation in humans. (PubMed id 11401879)9 O'Grady N.P....Suffredini A.F. (Am. J. Respir. Crit. Care Med. 2001)
    809. Expression of chemokines and chemokine receptors during human renal transplant rejection. (PubMed id 11228176)9 Segerer S....Alpers C.E. (Am. J. Kidney Dis. 2001)
    810. A molecular analysis of NKT cells: identification of a class-I restricted T cell-associated molecule (CRTAM). (PubMed id 10811014)9 Kennedy J.... Zlotnik A. (J. Leukoc. Biol. 2000)
    811. Inhibition of human immunodeficiency virus transmission to CD4+ T cells after gene transfer of constitutively expressed interferon beta to dendritic cells. (PubMed id 10954903)9 Cremer I....De Maeyer E. (Hum. Gene Ther. 2000)
    812. Cytokine gene expression and T-cell proliferative responses in lymph node mononuclear cells from children with early stage human immunodeficiency virus infection. (PubMed id 11114129)9 Airoldi I....Pistoia V. (Haematologica 2000)
    813. Human immunodeficiency virus type 1 infection is associated with significant mucosal inflammation characterized by increased expression of CCR5, CXCR4, and beta-chemokines. (PubMed id 11069233)9 Olsson J....Anton P. (J. Infect. Dis. 2000)
    814. Cyclooxygenase inhibition increases interleukin 5 and interleukin 13 production and airway hyperresponsiveness in allergic mice. (PubMed id 10934105)9 Peebles R.S....Sheller J.R. (Am. J. Respir. Crit. Care Med. 2000)
    815. Comprehensive gene expression profile of LPS-stimulated human monocytes by SAGE. (PubMed id 11001915)9 Suzuki T....Matsushima K. (Blood 2000)
    816. Up-regulation of beta-chemokines and down-modulation of CCR5 co-receptors inhibit simian immunodeficiency virus transmission in non-human primates. (PubMed id 10792505)9 Lehner T....Bergmeier L. (Immunology 2000)
    817. High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. (PubMed id 10952726)9 Andersson U....Tracey K.J. (J. Exp. Med. 2000)
    818. Effect of thalidomide on chemokine production by human microglia. (PubMed id 10950803)9 Lokensgard J.R....Peterson P.K. (J. Infect. Dis. 2000)
    819. The role of HIV-related chemokine receptors and chemokines in human erythropoiesis in vitro. (PubMed id 10742385)9 Majka M....Ratajczak M.Z. (Stem Cells 2000)
    820. Differential desensitization of lipopolysaccharide-inducible chemokine gene expression in human monocytes and macrophages. (PubMed id 10898491)9 Kaufmann A....Sprenger H. (Eur. J. Immunol. 2000)
    821. CD14+CD16++ cells derived in vitro from peripheral blood monocytes exhibit phenotypic and functional dendritic cell-like characteristics. (PubMed id 10940876)9 Ancuta P....Haeffner-Cavaillon N. (Eur. J. Immunol. 2000)
    822. Semi-quantification of human C-C chemokine mRNAs with reverse transcription/real-time PCR using multi-specific standards. (PubMed id 10915853)9 Dumoulin F.L....Spengler U. (J. Immunol. Methods 2000)
    823. Reduction of chemokine levels and leukocyte traffic to joints by tumor necrosis factor alpha blockade in patients with rheumatoid arthritis. (PubMed id 10643698)9 Taylor P.C....Maini R.N. (Arthritis Rheum. 2000)
    824. Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes. (PubMed id 10934220)9 Tilton B....Thelen M. (J. Exp. Med. 2000)
    825. Control of chemokine production at the blood-retina barrier. (PubMed id 11106948)9 Crane I.J....Forrester J.V. (Immunology 2000)
    826. HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation. (PubMed id 10758170)9 Liu Q.H....Freedman B.D. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    827. Toxoplasma gondii induces the secretion of monocyte chemotactic protein-1 in human fibroblasts, in vitro. (PubMed id 10942204)9 Brenier-Pinchart M.P....Ambroise-Thomas P. (Mol. Cell. Biochem. 2000)
    828. Chemokine signaling and HIV-1 fusion mediated by macrophage CXCR4: implications for target cell tropism. (PubMed id 10985246)9 Collman R.G....Freedman B.D. (J. Leukoc. Biol. 2000)
    829. Characterization of binding sites for chemokines MCP-1 and MIP-1alpha on human brain microvessels. (PubMed id 11032879)9 Andjelkovic A.V. and Pachter J.S. (J. Neurochem. 2000)
    830. High levels of IL-10 and determination of other cytokines and chemokines in HIV-associated haemophagocytic syndrome. (PubMed id 10931148)9 Benveniste O....Dormont D. (Clin. Exp. Immunol. 2000)
    831. Chemokines are the main proinflammatory mediators in human monocytes activated by Staphylococcus aureus, peptidoglycan, and endotoxin. (PubMed id 10751418)9 Wang Z.M....Dziarski R. (J. Biol. Chem. 2000)
    832. Cholera toxin induces maturation of human dendritic cells and licences them for Th2 priming. (PubMed id 10940931)9 Gagliardi M.C....De Magistris M.T. (Eur. J. Immunol. 2000)
    833. Pseudomonas aeruginosa exoenzyme S induces transcriptional expression of proinflammatory cytokines and chemokines. (PubMed id 10899895)9 Epelman S....Mody C.H. (Infect. Immun. 2000)
    834. Cryptosporidium parvum infection stimulates the secretion of TGF-beta, IL-8 and RANTES by Caco-2 cell line. (PubMed id 11133108)9 Maillot C....Favennec L. (Parasitol. Res. 2000)
    835. Role for CD40-CD40 ligand interactions in the immune response to solid tumours. (PubMed id 11163401)9 Alexandroff A.B....Taub D.D. (Mol. Immunol. 2000)
    836. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. (PubMed id 10742149)9 Otterbein L.E....Choi A.M. (Nat. Med. 2000)
    837. The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. (PubMed id 10996027)9 Li B.Q....Wang J.M. (Immunopharmacology 2000)
    838. Sequential expression of chemokines in experimental autoimmune neuritis. (PubMed id 11024541)9 Kieseier B.C....Hartung H.P. (J. Neuroimmunol. 2000)
    839. RANTES activates antigen-specific cytotoxic T lymphocytes in a mitogen-like manner through cell surface aggregation. (PubMed id 10917892)9 Appay V....Rowland-Jones S. (Int. Immunol. 2000)
    840. Distinct patterns of stimulus-inducible chemokine mRNA accumulation in human fetal astrocytes and microglia. (PubMed id 10696146)9 Hua L.L. and Lee S.C. (Glia 2000)
    841. Soluble CD40 ligand induces beta-chemokine production by macrophages and resistance to HIV-1 entry. (PubMed id 11023663)9 di Marzio P....Landau N.R. (Cytokine 2000)
    842. CKbeta-8 [CCL23], a novel CC chemokine, is chemotactic for human osteoclast precursors and is expressed in bone tissues. (PubMed id 10737895)9 Votta B.J....Gowen M. (J. Cell. Physiol. 2000)
    843. Redox regulation of chemokine receptor expression. (PubMed id 10716998)9 Saccani A....Sica A. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    844. Chemokine- and cytokine-induced expression of endothelin 1 and endothelin-converting enzyme 1 in endothelial cells. (PubMed id 10669855)9 Molet S....Giaid A. (J. Allergy Clin. Immunol. 2000)
    845. Constitutive expression of stromal derived factor-1 by mucosal epithelia and its role in HIV transmission and propagation. (PubMed id 10744978)9 Agace W.W....Parker C.M. (Curr. Biol. 2000)
    846. Macrophage infiltration in human non-small-cell lung cancer: the role of CC chemokines. (PubMed id 10823415)9 Arenberg D.A....Strieter R.M. (Cancer Immunol. Immunother. 2000)
    847. Biological parameters of HIV-1 infection in primary intestinal lymphocytes and macrophages. (PubMed id 10985252)9 Smith P.D....Shaw G.M. (J. Leukoc. Biol. 2000)
    848. The neutrophil as a cellular source of chemokines. (PubMed id 11138776)9 Scapini P....Cassatella M.A. (Immunol. Rev. 2000)
    849. Ablation of tumor necrosis factor receptor type I (p55) alters oxygen-induced lung injury. (PubMed id 10781441)9 Pryhuber G.S....Nahm M.H. (Am. J. Physiol. Lung Cell Mol. Physiol. 2000)
    850. Biological significance of the expression of HIV-related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines. (PubMed id 11021758)9 Majka M....Ratajczak M.Z. (Leukemia 2000)
    851. Distinct patterns and kinetics of chemokine production regulate dendritic cell function. (PubMed id 10359116)9 Sallusto F....Lanzavecchia A. (Eur. J. Immunol. 1999)
    852. Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees. (PubMed id 9952371)9 Lauw F.N....van der Poll T. (J. Infect. Dis. 1999)
    853. The epithelial cell response to rotavirus infection. (PubMed id 10510386)9 Rollo E.E....Shaw R.D. (J. Immunol. 1999)
    854. Chemokines: signal lamps for trafficking of T and B cells for development and effector function. (PubMed id 9886241)9 Kim C.H. and Broxmeyer H.E. (J. Leukoc. Biol. 1999)
    855. Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates. (PubMed id 9847323)9 Albright A.V....GonzA!lez-Scarano F. (J. Virol. 1999)
    856. Chemokines induce migration and changes in actin polymerization in adult rat brain microglia and a human fetal microglial cell line in vitro. (PubMed id 9890430)9 Cross A.K. and Woodroofe M.N. (J. Neurosci. Res. 1999)
    857. Human thymocytes express CCR-3 and are activated by eotaxin. (PubMed id 10233874)9 Franz-Bacon K....Bacon K.B. (Blood 1999)
    858. Induction of CC chemokines in human peripheral blood mononuclear cells by staphylococcal exotoxins and its prevention by pentoxifylline. (PubMed id 10411004)9 Krakauer T. (J. Leukoc. Biol. 1999)
    859. Interferon-gamma upregulates CCR5 expression in cord and adult blood mononuclear phagocytes. (PubMed id 9949155)9 Hariharan D....Ho W.Z. (Blood 1999)
    860. Abundant expression of chemokines in malignant and infective human lymphadenopathies. (PubMed id 10419655)9 Tedla N....Lloyd A. (Cytokine 1999)
    861. Chemokine receptor expression and signaling in macaque and human fetal neurons and astrocytes: implications for the neuropathogenesis of AIDS. (PubMed id 10415069)9 Klein R.S....Luster A.D. (J. Immunol. 1999)
    862. Structure and function of the CC chemokine receptor (CCR) 8. (PubMed id 10611408)9 Napolitano M. and Santoni A. (Forum (Genova) 1999)
    863. The B-oligomer of pertussis toxin deactivates CC chemokine receptor 5 and blocks entry of M-tropic HIV-1 strains. (PubMed id 10477545)9 Alfano M....Bukrinsky M. (J. Exp. Med. 1999)
    864. Negative feedback between prostaglandin and alpha- and beta-chemokine synthesis in human microglial cells and astrocytes. (PubMed id 9973432)9 Janabi N....Tardieu M. (J. Immunol. 1999)
    865. Acute cellular rejection of human renal tissue by adoptive transfer of allogeneic human peripheral blood mononuclear cells into chimeric rats: sequential gene expression of cytokines, chemokines and cytolytic effector molecules, and their regulation by CTLA-4-Ig. (PubMed id 10508185)9 Dekel B....Reisner Y. (Int. Immunol. 1999)
    866. Islet-specific Th1, but not Th2, cells secrete multiple chemokines and promote rapid induction of autoimmune diabetes. (PubMed id 10072490)9 Bradley L.M....Sarvetnick N. (J. Immunol. 1999)
    867. Chemokine-induced phosphorylation of CC chemokine receptor 5 (CCR5). (PubMed id 10080528)9 Olbrich H....Oppermann M. (J. Leukoc. Biol. 1999)
    868. LD78beta, a non-allelic variant of human MIP-1alpha (LD78alpha), has enhanced receptor interactions and potent HIV suppressive activity. (PubMed id 10364178)9 Nibbs R.J....Graham G.J. (J. Biol. Chem. 1999)
    869. Chemokine and chemokine receptor expression in a novel human mesangial cell line. (PubMed id 10541290)9 Banas B....SchlAPndorff D. (J. Am. Soc. Nephrol. 1999)
    870. Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity. (PubMed id 10383387)9 Blanpain C....Parmentier M. (J. Biol. Chem. 1999)
    871. Differential effects of human immunodeficiency virus isolates on beta-chemokine and gamma interferon production and on cell proliferation. (PubMed id 9882358)9 Greco G....Levy J.A. (J. Virol. 1999)
    872. Signaling through CD43 induces natural killer cell activation, chemokine release, and PYK-2 activation. (PubMed id 10515880)9 Nieto M....SA!nchez-Madrid F. (Blood 1999)
    873. Regulation of dendritic cell trafficking: a process that involves the participation of selective chemokines. (PubMed id 10449163)9 Dieu-Nosjean M.C....Caux C. (J. Leukoc. Biol. 1999)
    874. Calcium responses elicited in human T cells and dendritic cells by cell-cell interaction and soluble ligands. (PubMed id 10323209)9 Montes M....Trautmann A. (Int. Immunol. 1999)
    875. Differential cytokine and chemokine gene expression by human NK cells following activation with IL-18 or IL-15 in combination with IL-12: implications for the innate immune response. (PubMed id 10201989)9 Fehniger T.A....Caligiuri M.A. (J. Immunol. 1999)
    876. Aminooxypentane-RANTES, an inhibitor of R5 human immunodeficiency virus type 1, increases the interferon gamma to interleukin 10 ratio without impairing cellular proliferation. (PubMed id 10408722)9 Rusconi S....Clerici M. (AIDS Res. Hum. Retroviruses 1999)
    877. Induction of cytokines and chemokines in human monocytes by Mycoplasma fermentans-derived lipoprotein MALP-2. (PubMed id 10569741)9 Kaufmann A....Sprenger H. (Infect. Immun. 1999)
    878. Dendritic cells and MPIF-1: chemotactic activity and inhibition of endogenous chemokine production by IFN-gamma and CD40 ligation. (PubMed id 10380905)9 Nardelli B....Garotta G. (J. Leukoc. Biol. 1999)
    879. Peptide T blocks GP120/CCR5 chemokine receptor-mediated chemotaxis. (PubMed id 10527688)9 Redwine L.S....Ruff M.R. (Clin. Immunol. 1999)
    880. Chemical synthesis and characterization of chemokine RANTES and its analogues. (PubMed id 10080874)9 Boykins R.A....Syin C. (Cytokine 1999)
    881. Semiquantitation of human chemokine mRNA levels with a newly constructed multispecific competitor fragment. (PubMed id 10357207)9 Dumoulin F.L....Spengler U. (J. Immunol. Methods 1999)
    882. Highly potent RANTES analogues either prevent CCR5-using human immunodeficiency virus type 1 infection in vivo or rapidly select for CXCR4-using variants. (PubMed id 10196243)9 Mosier D.E....Wilken J. (J. Virol. 1999)
    883. H-Ras signals to cytoskeletal machinery in induction of integrin-mediated adhesion of T cells. (PubMed id 10570313)9 Tanaka Y....Eto S. (J. Immunol. 1999)
    884. Lineage-specific expression of human immunodeficiency virus (HIV) receptor/coreceptors in differentiating hematopoietic precursors: correlation with susceptibility to T- and M-tropic HIV and chemokine-mediated HIV resistance. (PubMed id 10477684)9 Chelucci C....Peschle C. (Blood 1999)
    885. Sequential measurements of chemokines in urosepsis and experimental endotoxemia. (PubMed id 10634213)9 Olszyna D.P....Van Der Poll T. (J. Clin. Immunol. 1999)
    886. The V3 loop-mimicking pseudopeptide 5[Kpsi(CH2N)PR]-TASP inhibits HIV infection in primary macrophage cultures. (PubMed id 10082122)9 Seddiki N....Hovanessian A.G. (AIDS Res. Hum. Retroviruses 1999)
    887. Chemokine receptor expression by human intestinal epithelial cells. (PubMed id 10419917)9 Dwinell M.B....Kagnoff M.F. (Gastroenterology 1999)
    888. Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease. (PubMed id 10190688)9 Xia M.Q. and Hyman B.T. (J. Neurovirol. 1999)
    889. A synthetic peptide derived from human immunodeficiency virus type 1 gp120 downregulates the expression and function of chemokine receptors CCR5 and CXCR4 in monocytes by activating the 7-transmembrane G-protein-coupled receptor FPRL1/LXA4R. (PubMed id 10438703)9 Deng X....Wang J.M. (Blood 1999)
    890. Blocking HIV co-receptors by chemokines. (PubMed id 10463536)9 Virelizier J.L. (Dev. Biol. Stand. 1999)
    891. Bone marrow CD34(+) cells and megakaryoblasts secrete beta-chemokines that block infection of hematopoietic cells by M-tropic R5 HIV. (PubMed id 10606628)9 Majka M....Ratajczak M.Z. (J. Clin. Invest. 1999)
    892. Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells. (PubMed id 10382767)9 Sallusto F....Lanzavecchia A. (Eur. J. Immunol. 1999)
    893. Identification of a T cell chemotactic factor in the cerebrospinal fluid of HIV-1-infected individuals as interferon-gamma inducible protein 10. (PubMed id 10378881)9 Kolb S.A....Fontana A. (J. Neuroimmunol. 1999)
    894. Dendritic cell chemotaxis and transendothelial migration are induced by distinct chemokines and are regulated on maturation. (PubMed id 9862347)9 Lin C.L....Roake J.A. (Eur. J. Immunol. 1998)
    895. Antigen-specific release of beta-chemokines by anti-HIV-1 cytotoxic T lymphocytes. (PubMed id 9512422)9 Price D.A....Phillips R.E. (Curr. Biol. 1998)
    896. Prostaglandin E2 induces resistance to human immunodeficiency virus-1 infection in monocyte-derived macrophages: downregulation of CCR5 expression by cyclic adenosine monophosphate. (PubMed id 9639497)9 Thivierge M....Rola-Pleszczynski M. (Blood 1998)
    897. Inhibition of HIV type 1 infection with a RANTES-IgG3 fusion protein. (PubMed id 9870314)9 Challita-Eid P.M....Planelles V. (AIDS Res. Hum. Retroviruses 1998)
    898. Heparan sulfate proteoglycan on endothelium efficiently induces integrin-mediated T cell adhesion by immobilizing chemokines in patients with rheumatoid synovitis. (PubMed id 9704634)9 Tanaka Y....Eto S. (Arthritis Rheum. 1998)
    899. Human herpesvirus 6 open reading frame U12 encodes a functional beta-chemokine receptor. (PubMed id 9621074)9 Isegawa Y....Yamanishi K. (J. Virol. 1998)
    900. Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4. (PubMed id 9430724)9 Imai T.... Gray P.W. (J. Biol. Chem. 1998)
    901. Natural truncation of RANTES abolishes signaling through the CC chemokine receptors CCR1 and CCR3, impairs its chemotactic potency and generates a CC chemokine inhibitor. (PubMed id 9565366)9 Struyf S....Van Damme J. (Eur. J. Immunol. 1998)
    902. In situ analysis of C-C chemokine mRNA in human glomerulonephritis. (PubMed id 9734607)9 Cockwell P....Savage C.O. (Kidney Int. 1998)
    903. Induction of human immunodeficiency virus type 1 replication in human glial cells after proinflammatory cytokines stimulation: effect of IFNgamma, IL1beta, and TNFalpha on differentiation and chemokine production in glial cells. (PubMed id 9671961)9 Janabi N....Tardieu M. (Glia 1998)
    904. Immunohistochemical study of the beta-chemokine receptors CCR3 and CCR5 and their ligands in normal and Alzheimer's disease brains. (PubMed id 9665462)9 Xia M.Q....Hyman B.T. (Am. J. Pathol. 1998)
    905. In vitro p24 antigen-stimulated lymphocyte proliferation and beta-chemokine production in human immunodeficiency virus type 1 (HIV-1)-seropositive subjects after immunization with an inactivated gp120-depleted HIV-1 immunogen (Remune). (PubMed id 9605982)9 Moss R.B....Carlo D.J. (Clin. Diagn. Lab. Immunol. 1998)
    906. A trauma-like elevation of plasma cytokines in humans in response to treadmill running. (PubMed id 9824725)9 Ostrowski K....Pedersen B.K. (J. Physiol. (Lond.) 1998)
    907. Beta-chemokines MCP-1 and RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus-associated dementia. (PubMed id 9818943)9 Kelder W....Griffin D.E. (Ann. Neurol. 1998)
    908. Chemokine receptor expression on resident and inflammatory cells in the brain of macaques with simian immunodeficiency virus encephalitis. (PubMed id 9502406)9 Westmoreland S.V....Sasseville V.G. (Am. J. Pathol. 1998)
    909. Effect of N-terminal truncation and solution conditions on chemokine dimer stability: nuclear magnetic resonance structural analysis of macrophage inflammatory protein 1 beta mutants. (PubMed id 9649315)9 Laurence J.S....LiWang P.J. (Biochemistry 1998)
    910. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. (PubMed id 9466968)9 Qin S....Mackay C.R. (J. Clin. Invest. 1998)
    911. Interaction of human immunodeficiency virus type 1 envelope glycoprotein V3 loop with CCR5 and CD4 at the membrane of human primary macrophages. (PubMed id 9870313)9 Rabehi L....Gattegno L. (AIDS Res. Hum. Retroviruses 1998)
    912. Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions. (PubMed id 9628469)9 Simpson J.E....Woodroofe M.N. (J. Neuroimmunol. 1998)
    913. Interleukin-6 induces monocyte chemotactic protein-1 in peripheral blood mononuclear cells and in the U937 cell line. (PubMed id 9414293)9 Biswas P....Poli G. (Blood 1998)
    914. gp120 envelope glycoproteins of human immunodeficiency viruses competitively antagonize signaling by coreceptors CXCR4 and CCR5. (PubMed id 9653130)9 Madani N....Kabat D. (Proc. Natl. Acad. Sci. U.S.A. 1998)
    915. Chemokines and chemotaxis of leukocytes in infectious meningitis. (PubMed id 9626995)9 Lahrtz F....Fontana A. (J. Neuroimmunol. 1998)
    916. Constitutive chemokine production results in activation of leukocyte function-associated antigen-1 on adult T-cell leukemia cells. (PubMed id 9573029)9 Tanaka Y....Eto S. (Blood 1998)
    917. Beta-chemokine receptor CCR5 signals via the novel tyrosine kinase RAFTK. (PubMed id 9446638)9 Ganju R.K....Groopman J.E. (Blood 1998)
    918. Chemokine sequestration by viral chemoreceptors as a novel viral escape strategy: withdrawal of chemokines from the environment of cytomegalovirus-infected cells. (PubMed id 9730887)9 Bodaghi B....Michelson S. (J. Exp. Med. 1998)
    919. Small molecule inhibitor of HIV-1 cell fusion blocks chemokine receptor-mediated function. (PubMed id 9665268)9 Howard O.M....Oppenheim J.J. (J. Leukoc. Biol. 1998)
    920. CCR5 has an expanded ligand-binding repertoire and is the primary receptor used by MCP-2 on activated T cells. (PubMed id 9790730)9 Ruffing N....Wu L. (Cell. Immunol. 1998)
    921. Ischemic stroke is associated with a systemic increase of blood mononuclear cells expressing interleukin-8 mRNA. (PubMed id 9472890)9 Kostulas N....Link H. ( a journal of cerebral circulation 1998)
    922. Cytokine and chemokine regulation of proMMP-9 and TIMP-1 production by human peripheral blood lymphocytes. (PubMed id 9036981)9 Johnatty R.N....Rees R.C. (J. Immunol. 1997)
    923. Do beta-chemokines have clinical relevance in HIV infection? (PubMed id 9259592)9 Mackewicz C.E....Levy J.A. (J. Clin. Invest. 1997)
    924. Chemokine and matrix metalloproteinase secretion by myelin proteolipid protein-specific CD8+ T cells: potential roles in inflammation. (PubMed id 9120256)9 Biddison W.E....Honma K. (J. Immunol. 1997)
    925. Chemokines induce migrational responses in human breast carcinoma cell lines. (PubMed id 9139852)9 Youngs S.J....Rees R.C. (Int. J. Cancer 1997)
    926. Beta-chemokines that inhibit HIV-1 infection of human macrophages stimulate uptake and promote destruction of Trypanosoma cruzi by human macrophages. (PubMed id 9449540)9 Lima M.F....Villalta F. (Cell. Mol. Biol. (Noisy-le-grand) 1997)
    927. Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7. (PubMed id 9153236)9 Yoshida R.... Yoshie O. (J. Biol. Chem. 1997)
    928. Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: a counterregulatory mechanism that restrains the immune response. (PubMed id 9151701)9 Zhang M....Tracey K.J. (J. Exp. Med. 1997)
    929. Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses. (PubMed id 9343222)9 Kuhmann S.E.... Kabat D. (J. Virol. 1997)
    930. Identification of CCR6, the specific receptor for a novel lymphocyte- directed CC chemokine LARC. (PubMed id 9169459)9 Baba M.... Yoshie O. (J. Biol. Chem. 1997)
    931. RSV infection of human airway epithelial cells causes production of the beta-chemokine RANTES. (PubMed id 9124609)9 Becker S....Noah T.L. (Am. J. Physiol. 1997)
    932. The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. (PubMed id 9169480)9 Imai T.... Yoshie O. (J. Biol. Chem. 1997)
    933. Regulation of anti-HIV-1 activity of RANTES by heparan sulfate proteoglycans. (PubMed id 9379060)9 Oravecz T....Norcross M.A. (J. Immunol. 1997)
    934. Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4. (PubMed id 9334378)9 Schols D....De Clercq E. (J. Exp. Med. 1997)
    935. Interaction of chemokine receptor CCR5 with its ligands: multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding. (PubMed id 9334377)9 Wu L....Mackay C.R. (J. Exp. Med. 1997)
    936. Differential production of and migratory response to beta chemokines by human microglia and astrocytes. (PubMed id 9203678)9 Peterson P.K....Chao C.C. (J. Infect. Dis. 1997)
    937. The human CC chemokine receptor 5 (CCR5) gene. Multiple transcripts with 5'-end heterogeneity, dual promoter usage, and evidence for polymorphisms within the regulatory regions and noncoding exons. (PubMed id 9388201)9 Mummidi S.... Ahuja S.K. (J. Biol. Chem. 1997)
    938. CKbeta8, a novel CC chemokine that predominantly acts on monocytes. (PubMed id 9187369)9 Forssmann U....Baggiolini M. (FEBS Lett. 1997)
    939. C3a and C5a stimulate chemotaxis of human mast cells. (PubMed id 9108406)9 Hartmann K....Zuberbier T. (Blood 1997)
    940. Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines. (PubMed id 9257866)9 Sozzani S....Mantovani A. (J. Immunol. 1997)
    941. Molecular cloning and characterization of a cDNA, CHEMR1, encoding a chemokine receptor with a homology to the human C-C chemokine receptor, CCR-4. (PubMed id 9192769)9 Youn B.S....Kwon B.S. (Blood 1997)
    942. Human immunodeficiency virus-1 entry into purified blood dendritic cells through CC and CXC chemokine coreceptors. (PubMed id 9269754)9 Ayehunie S....Ruprecht R.M. (Blood 1997)
    943. HIV-1 entry and macrophage inflammatory protein-1beta-mediated signaling are independent functions of the chemokine receptor CCR5. (PubMed id 9054370)9 Farzan M....Gerard C. (J. Biol. Chem. 1997)
    944. [The in vitro induction of monocyte chemotactic protein-1 and interleukin-8 in whole human blood by low molecular weight thymus peptides]. (PubMed id 8992963)9 Mayer G....Schmitz H. (Arzneimittelforschung 1996)
    945. Molecular cloning and functional expression of a novel CC chemokine receptor cDNA from a human basophilic cell line. (PubMed id 7642634)9 Power C.A.... Wells T.N.C. (J. Biol. Chem. 1995)
    946. Direct exposure to nitrogen dioxide fails to induce the expression of some inflammatory cytokines in an IC-21 murine macrophage cell model. (PubMed id 8560494)9 Tu B....Cotgreave I.A. (Toxicology 1995)

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    Entrez Gene: 6351 HGNC: 10630 AceView: CCL4 Ensembl:ENSG00000129277 euGenes: HUgn6351
    ECgene: CCL4 Kegg: 6351 H-InvDB: CCL4

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    PharmGKB entry for CCL4 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CCL4 Genetics and Cytogenetics in Oncology and Haematology
    Wikipedia http://en.wikipedia.org/wiki/Macrophage_Inflammatory_Protein

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