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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CCL3L1 Gene

protein-coding   GIFtS: 53
GCID: GC17M034623

chemokine (C-C motif) ligand 3-like 1

(Previous name: small inducible cytokine A3-like 1 )
(Previous symbols: D17S1718, SCYA3L, SCYA3L1)
 Explore 17 diseases affiliated with
CCL3L1 via our new
 Human Malady Compendium 
Biological research products
for CCL3L1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Chemokine (C-C Motif) Ligand 3-Like 11 2     Tonsillar Lymphocyte LD78 Beta Protein2 3
SCYA3L11 2 3 5     LD78-Beta(1-70)1
D17S17181 2 3     G0/G1 Switch Regulatory Protein 19-22 3
G0S19-21 2 3     PAT 464.22 3
LD78BETA1 2     LD782 5
SCYA3L1 2     464.22
Small Inducible Cytokine A3-Like 11 2     MIP1AP2
Small-Inducible Cytokine A3-Like 12 3     C-C Motif Chemokine 3-Like 12

External Ids:    HGNC: 106281   Entrez Gene: 63492   Ensembl: ENSG000002050217   OMIM: 6013955   UniProtKB: P166193   

Export aliases for CCL3L1 gene to outside databases

Previous GC identifers: GC17U990089 GC17M036564 GC17M034769 GC17M031635 GC17M034522


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CCL3L1:
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted
proteins involved in immunoregulatory and inflammatory processes. This protein binds to several chemokine receptors
including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and
binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals; most
individuals have 1-6 copies in the diploid genome, although rare individuals have zero or more than six copies. The
human genome reference assembly contains two full copies of the gene (CCL3L3 and CCL3L1) and a partial pseudogene.
This record represents the more telomeric full-length gene. (provided by RefSeq, Apr 2010)

UniProtKB/Swiss-Prot: CL3L1_HUMAN, P16619
Function: Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of
HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a
very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5

Gene Wiki entry for CCL3L1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010799.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CCL3L1 gene promoter:
         HOXA9B   AML1a   Pbx1a   AP-1   CUTL1   LCR-F1   MEF-2A   HSF2   c-Myb   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCL3L1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CCL3L1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCL3L1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.1   Ensembl cytogenetic band:  17q12   HGNC cytogenetic band: 17q12

CCL3L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCL3L1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M034623:  view genomic region     (about GC identifiers)

Start:
34,623,842 bp from pter      End:
34,625,731 bp from pter
Size:
1,890 bases      Orientation:
minus strand

1 alternative location:
Chr17-,PATCHES 34,536,480-34,538,368     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CL3L1_HUMAN, P16619 (See protein sequence)
Recommended Name: C-C motif chemokine 3-like 1 precursor  
Size: 93 amino acids; 10161 Da
Subcellular location: Secreted
Secondary accessions: A6NGK6 B2RUX4 Q3B7A8 Q53YA5 Q96I68

Explore the universe of human proteins at neXtProt for CCL3L1: NX_P16619

Post-translational modifications:

  • The N-terminal processed forms LD78-beta(3-70) and LD78-beta(5-70) are produced by proteolytic cleavage after secretion
  • from peripheral blood monocytes. The cleavage to yield LD78-beta(3-70) is probably achieved by DPP41
  • View neXtProt modification sites for NX_P16619

  • CCL3L1 Protein expression data from MOPED and PaxDb: --
    REFSEQ proteins: NP_066286.1  
    ENSEMBL proteins: 
     ENSP00000465806   ENSP00000408984   ENSP00000437533  
    Reactome Protein details: P16619
    Human Recombinant Protein Products: 
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    Novus Biologicals CCL3L1 Lysate
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for CCL3L1
    Uscn Proteins for CCL3L1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005615extracellular space ----


    CCL3L1 for ontologies           About GeneDecksing



    CCL3L1 Antibody Products: 
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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CCL3L1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR000827 Chemokine_CC_CS
     IPR001811 Chemokine_IL8-like_dom

    Graphical View of Domain Structure for InterPro Entry P16619

    ProtoNet protein and cluster: P16619

    1 Blocks protein family: IPB000827 Small chemokine

    UniProtKB/Swiss-Prot: CL3L1_HUMAN, P16619
    Similarity: Belongs to the intercrine beta (chemokine CC) family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CL3L1_HUMAN, P16619
    Function: Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of
    HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a
    very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5

    miRNA
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    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CCL3L1

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008009chemokine activity ----


    CCL3L1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for CCL3L1:
     Increased gamma-H2AX phosphory 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/9 super-pathways (see all 9About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1PEDF Induced Signaling
    8/12 pathways (see all 12)
    PEDF Induced Signaling1.00
    STAT3 Pathway0.47
    MIF Mediated Glucocorticoid Regulation0.73
    Endothelin-1 Signaling Pathway0.44
    MIF Regulation of Innate Immune Cells0.71
    NFAT Signaling and Lymphocyte Interactions0.37
    IL-6 Pathway0.61
    PGC1Alpha Pathway0.33
    2TGF-Beta Pathway
    TGF-Beta Pathway1.00
    JNK Pathway0.50
    MAPK Family Pathway0.60
    Regulation of eIF4 and p70S6K0.43
    JAK-STAT Pathway0.57
    SOCS Pathway0.29
    3Akt Signaling
    Akt Signaling1.00
    Tec Kinases Signaling0.55
    p38 Signaling0.60
    4Rho Family GTPases
    Rho Family GTPases1.00
    Molecular Mechanisms of Cancer0.51
    ERK Signaling0.61
    5PAK Pathway
    PAK Pathway1.00
    Antioxidant Action of Vitamin-C0.56

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5/27 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CCL3L1 (see all 27)
        Endothelin-1 Signaling Pathway
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C
    NFAT Signaling and Lymphocyte Interactions
    JNK Pathway

    5/6        Reactome Pathways for CCL3L1 (see all 6)
        Peptide ligand-binding receptors
    Chemokine receptors bind chemokines
    Signal Transduction
    Signaling by GPCR
    GPCR ligand binding


    4         Kegg Pathways  (Kegg details for CCL3L1):
        Cytokine-cytokine receptor interaction
    Chemokine signaling pathway
    Chagas disease (American trypanosomiasis)
    Rheumatoid arthritis


    CCL3L1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCL3L1

    5 Interacting proteins for CCL3L1 (P166193) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCR3P516773I2D: score=4 
    CCR5P516813I2D: score=4 
    CCBP2O005903I2D: score=3 
    CCR1P322463I2D: score=3 
    DPP4P274873I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006935chemotaxis ----
    GO:0006954inflammatory response ----
    GO:0006955immune response ----
    GO:0008285negative regulation of cell proliferation ----


    CCL3L1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CCL3L1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CCL3L1
    4 Novoseek chemical compound relationships for CCL3L1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    ccl3 78.1 6 12355456 (2), 17330138 (2), 20233400 (1)
    rantes 69.4 4 11287590 (2), 15662971 (1), 10449444 (1)
    ccl4 52.7 2 17330138 (2)
    calcium 0 2 10449444 (1), 11449371 (1)

    Search CenterWatch for drugs/clinical trials and news about CCL3L1 / CL3L1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CCL3L1 gene: 
    NM_021006.4  

    Unigene Cluster for CCL3L1:

    Chemokine (C-C motif) ligand 3-like 1
    Hs.512683  [show with all ESTs]
    Unigene Representative Sequence: BF662985
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000498676(uc002kif.1) ENST00000422211 ENST00000492788(uc002kig.1)
    ENST00000542124

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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCL3L1

    Additional cDNA sequence: 

    BC027888.1 BC107710.1 BC146914.1 X52149.1 

    6 DOTS entries:

    DT.100035793  DT.120948225  DT.449023  DT.97858828  DT.100759261  DT.95371117 

    24/42 AceView cDNA sequences (see all 42):

    BU626588 AA382113 AA362273 AA362364 NM_021006 CA430410 BC027888 BI839085 
    CF128666 N47995 AL543270 AA366594 AA361985 R54639 AA371389 X52149 
    AA380745 AA362365 AA382070 BM992482 AV647106 AW959359 BT006783 AW059858 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CCL3L1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    Genevestigator expression for CCL3L1

    SOURCE GeneReport for Unigene cluster: Hs.512683
        SABiosciences Expression via Pathway-Focused PCR Arrays including CCL3L1 (see all 15): 
              Nephrotoxicity in human mouse rat
              Fibrosis in human mouse rat
              Antiviral Response in human mouse rat
              Multiple Sclerosis in human mouse rat
              Leukemia in human mouse rat

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    In Situ
    Assay Products:
     

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CCL3L1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CCL3L1 gene from 2/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves CCL41 chemokine (C-C motif) ligand 4 70(n)
    55.56(a)
      395551  NM_001030360.2  NP_001025531.2 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1937066
    si:dkeyp-59a8.36
    (see all 6)
    si:dkeyp-59a8.3
    (see all 6)
    35(a)
    29(a)
    (see all 6)
    many ↔ many
    many ↔ many
    (see all 6)
    25(25902180-25904281)
    20(38310380-38311158)


    ENSEMBL Gene Tree for CCL3L1 (if available)
    TreeFam Gene Tree for CCL3L1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CCL3L1 gene
    CCL3L31 2  CCL152  CCL162  CCL22  CCL142  CCL242  CCL4L12  CCL112  
    CCL4L22  CCL72  CCL52  CCL232  CCL42  CCL82  CCL132  CCL262  
    CCL32  CCL182  
    18/30 SIMAP similar genes for CCL3L1 using alignment to 2 protein entries:     CL3L1_HUMAN (see all proteins) (see all similar genes):
    CCL3    CCL3L3    CCL4    CCL4L2    LOC728835    CCL4L1
    CCL14    CCL18    CCL5    CCL16    CCL11    CCL7
    MCP-3    CCL15    CCL2    CCL13    CCL24    CCL26

    CCL3L1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: CL3L1_HUMAN, P16619
    Polymorphism: The copy number of the CCL3L1 gene varies among individuals; most individuals have 1-6 copies in the
    diploid genome, although rare individuals have zero or more than 6 copies


    9 NCBI SNPs in CCL3L1 are shown     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1491159891,2
    F--34624269(+) CACTCA/GGCTCC 2 P L mis11Minor allele frequency- G:0.00NA 3872
    rs1484386761,2
    C--34624839(+) ATCTGC/TCGGGA 2 R syn10--------
    rs1406661821,2
    ----34626836(+) TCTAAA/CGTGAA 1 -- us2k10--------
    rs1466478141,2
    ----34627292(+) ATCCTA/GTACTA 1 -- us2k10--------
    rs1512936431,2
    ----34626677(+) TTCTGA/GGAAAG 1 -- us2k10--------
    rs2004868911,2
    ----34623978(+) TCGGTC/TGTCAC 1 -- ut310--------
    rs1412163901,2
    ----34627482(+) AAATAG/TATTTA 1 -- us2k10--------
    rs1444647531,2
    ----34626903(+) CATTAC/TACAAA 1 -- us2k10--------
    rs1425727691,2
    ----34625253(+) GTGAAC/GAACAG 1 -- int10--------

    HapMap Linkage Disequilibrium report for CCL3L1 (34623842 - 34625731 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 28 variations for CCL3L1
         15/28 CNVs (see all 28): 77573 37558 7154 72878 88435 8841 72884 88444 30824 35451 35450 88441 5003 77579 72882
    Human Gene Mutation Database (HGMD): CCL3L1

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CCL3L1 for disorders           About GeneDecksing

    OMIM gene information: 601395   
    OMIM disorders: 609423  
    17 diseases for CCL3L1:    About MalaCards
    papillon-lefevre disease    hiv/aids    human immunodeficiency virus infectious disease    hemophilia
    kawasaki disease    chagas disease    rheumatoid arthritis    hepatitis c
    trypanosomiasis    immunodeficiency    hematopoiesis    arthritis
    asthma    glioblastoma    hepatitis    neuronitis
    hiv type 1

    1 disease from the University of Copenhagen DISEASES database for CCL3L1:
    Human immunodeficiency virus infectious disease

    3 Novoseek disease relationships for CCL3L1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    immunodeficiency 24.5 3 11734558 (1), 17330138 (1), 11287590 (1)
    glioma 22.4 2 15662971 (2)
    aids 21.5 8 19287150 (3)

    Human Genome Epidemiology (HuGE) Navigator: CCL3L1 (18 documents)

    Export disorders for CCL3L1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CCL3L1 gene, integrated from 9 sources (see all 66):
    (articles sorted by number of sources associating them with CCL3L1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Two inflammatory mediator cytokine genes are closely linked and variably amplified on chromosome 17q. (PubMed id 1972563)1, 2, 3 Irving S.G.... Kelly K. (1990)
    2. CCL3L1 and CCL4L1: variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infection. (PubMed id 17330138)1, 2, 9 Shao W....Kaslow R.A. (2007)
    3. Diverging binding capacities of natural LD78beta isoforms of macrophage inflammatory protein-1alpha to the CC chemokine receptors 1, 3 and 5 affect their anti-HIV-1 activity and chemotactic potencies for neutrophils and eosinophils. (PubMed id 11449371)1, 2, 9 Struyf S.... Van Damme J. (2001)
    4. Structures of human genes coding for cytokine LD78 and their expression. (PubMed id 1694014)1, 2, 9 Nakao M.... Shimada K. (1990)
    5. Nucleotide sequence of the third cytokine LD78 gene and mapping of all three LD78 gene loci to human chromosome 17. (PubMed id 1296815)1, 3, 9 Hirashima M....Shimada K. (1992)
    6. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Cleavage by CD26/dipeptidyl peptidase IV converts the chemokine LD78beta into a most efficient monocyte attractant and CCR1 agonist. (PubMed id 10961862)1, 2 Proost P....Van Damme J. (2000)
    9. Three human homologs of a murine gene encoding an inhibitor of stem cell proliferation. (PubMed id 2271120)1, 2 Blum S.... Forsdyke D.R. (1990)
    10. Evidence for an influence of chemokine ligand 3-like 1 (CCL3L1) gene copy number on susceptibility to rheumatoid arthritis. (PubMed id 17604289)1, 9 McKinney C....Merriman T.R. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6349 HGNC: 10628 AceView: CCL3L1andCCL3L2 Ensembl:ENSG00000205021 euGenes: HUgn6349
    ECgene: CCL3L1 Kegg: 6349 H-InvDB: CCL3L1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CCL3L1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CCL3L1 gene:
    Search GeneIP for patents involving CCL3L1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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