Aliases for CCL25 Gene
Aliases for CCL25 Gene
External Ids for CCL25 Gene
- HGNC: 10624
- Entrez Gene: 6370
- Ensembl: ENSG00000131142
- OMIM: 602565
- UniProtKB: O15444
Previous HGNC Symbols for CCL25 Gene
- SCYA25
Previous GeneCards Identifiers for CCL25 Gene
- GC19P008076
- GC19P008222
- GC19P008023
- GC19P007788
Summaries for CCL25 Gene
-
This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
GeneCards Summary for CCL25 Gene
CCL25 (C-C Motif Chemokine Ligand 25) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors and PEDF Induced Signaling. GO annotations related to this gene include hormone activity and chemokine receptor binding.
UniProtKB/Swiss-Prot for CCL25 Gene
-
Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCL25 Gene
Genomics for CCL25 Gene
Regulatory Elements for CCL25 Gene
Enhancers for CCL25 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CCL25 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CCL25 gene promoter:
Regulatory Element Products
Genomic Location for CCL25 Gene
- Chromosome:
- 19
- Start:
- 8,052,340 bp from pter
- End:
- 8,062,663 bp from pter
- Size:
- 10,324 bases
- Orientation:
- Plus strand
Genomic View for CCL25 Gene
Genes around CCL25 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.2 by Ensembl
- 19p13.2 by Entrez Gene
- 19p13.2 by HGNC
CCL25 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CCL25 Gene
Proteins for CCL25 Gene
-
Protein details for CCL25 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O15444-CCL25_HUMAN
- Recommended name:
- C-C motif chemokine 25
- Protein Accession:
- O15444
- A1L4J4
- A6NI52
- A8K9E7
- B5MCA5
- Q96KJ7
Protein attributes for CCL25 Gene
- Size:
- 150 amino acids
- Molecular mass:
- 16609 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for CCL25 Gene
Other Protein References for CCL25 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for CCL25 (CCL25/TECK)
-
Custom Antibody ServicesOriGene Antibodies for CCL25
- Novus Biologicals Antibodies for CCL25
-
Cloud-Clone Corp. Antibodies for CCL25
- Invitrogen Antibodies for CCL25
- antibodies-online Antibodies for CCL25: See all 83
- GeneTex CCL25 antibody for CCL25
-
Santa Cruz Biotechnology (SCBT) Antibodies for CCL25
Protein Products
- R&D Systems Proteins and Enzymes for CCL25 (CCL25/TECK)
-
OriGene Purified Proteins for CCL25
- Search Origene for MassSpec and Protein Over-expression Lysates for CCL25
- Origene Custom Protein Services for CCL25
- ProSpec Recombinant Proteins for CCL25
-
Cloud-Clone Corp. Proteins for CCL25
- antibodies-online Proteins for CCL25: See all 47
- Search antibodies-online for peptides
- GeneTex Proteins for CCL25
-
ProSci Proteins for CCL25
Assay Products
- R&D Systems ELISAs, Luminex Assays, and other biochemical assays for CCL25 (CCL25/TECK)
-
Cloud-Clone Corp Assay Kits for CCL25
- antibodies-online Kits for CCL25: See all 41
No data available for DME Specific Peptides for CCL25 Gene
Domains & Families for CCL25 Gene
Gene Families for CCL25 Gene
Protein Domains for CCL25 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CCL25 Gene
Graphical View of Domain Structure for InterPro Entry
O15444- Family:
-
- Belongs to the intercrine beta (chemokine CC) family.
Function for CCL25 Gene
Molecular function for CCL25 Gene
- UniProtKB/Swiss-Prot Function:
- Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005125 | cytokine activity | IEA | -- |
| GO:0005179 | hormone activity | TAS | 9285413 |
| GO:0008009 | chemokine activity | IDA,IEA | 18308860 |
| GO:0031735 | CCR10 chemokine receptor binding | IDA | 10706668 |
| GO:0042379 | chemokine receptor binding | IDA | 23341447 |
Phenotypes for CCL25 Gene
- MGI mutant phenotypes for CCL25:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for CCL25:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability
- Mildly decreased CFP-tsO45G cell surface transport
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Decreased NF-kappaB reporter expression
- Increased transferrin (TF) endocytosis
- Decreased IL-8 secretion
- Decreased shRNA abundance
- Downregulation of NFkappaB pathway
Animal Model Products
-
Taconic Biosciences Mouse Models for CCL25
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCL25
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CCL25 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCL25 gene
- Search ViGene Biosciences for CCL25
CRISPR Products
-
OriGene CRISPR knockouts for CCL25
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCL25
- GenScript: Design CRISPR guide RNA sequences for CCL25
miRNA for CCL25 Gene
- miRTarBase miRNAs that target CCL25
miRNA Products
- Search ViGene Biosciences for CCL25
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CCL25
- Browse OriGene Inhibitory RNA Products For CCL25
-
ViGene Biosciences ready-to-package AAV shRNAs for CCL25 gene
Clone Products
- Sino Biological Human cDNA Clone for CCL25
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CCL25
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCL25
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CCL25
-
ViGene Biosciences adenoviral particle packaged cDNA for CCL25 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CCL25 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCL25 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CCL25 Gene
Localization for CCL25 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CCL25 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| plasma membrane | 2 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA,TAS | -- |
| GO:0005615 | extracellular space | IEA,IBA | -- |
Pathways & Interactions for CCL25 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | PEDF Induced Signaling |
.61
|
.47
|
| 2 | TGF-Beta Pathway |
.60
.57
|
.51
.40
|
| 3 | Peptide ligand-binding receptors | ||
| 4 | Akt Signaling |
.60
.60
|
|
| 5 | ERK Signaling |
.61
|
|
Pathways by source for CCL25 Gene
8 Reactome pathways for CCL25 Gene
3 KEGG pathways for CCL25 Gene
1 R&D Systems pathway for CCL25 Gene
27 Qiagen pathways for CCL25 Gene
Interacting Proteins for CCL25 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001954 | positive regulation of cell-matrix adhesion | IDA | 18308860 |
| GO:0002548 | monocyte chemotaxis | IBA | -- |
| GO:0006935 | chemotaxis | TAS | 10640743 |
| GO:0006954 | inflammatory response | IBA,IEA | -- |
| GO:0006955 | immune response | IEA,TAS | 10640743 |
Transcripts for CCL25 Gene
mRNA/cDNA for CCL25 Gene
- (8) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (19) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CCL25 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CCL25
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCL25
- GenScript: Design CRISPR guide RNA sequences for CCL25
miRNA Products
- Search ViGene Biosciences for CCL25
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CCL25
- Browse OriGene Inhibitory RNA Products For CCL25
-
ViGene Biosciences ready-to-package AAV shRNAs for CCL25 gene
Clone Products
- Sino Biological Human cDNA Clone for CCL25
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CCL25
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCL25
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||
| SP2: |
Expression for CCL25 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for CCL25 Gene
This gene is overexpressed in Small Intestine - Terminal Ileum (x46.4).
NURSA nuclear receptor signaling pathways regulating expression of CCL25 Gene:
CCL25SOURCE GeneReport for Unigene cluster for CCL25 Gene:
Hs.310511mRNA Expression by UniProt/SwissProt for CCL25 Gene:
O15444-CCL25_HUMAN
Tissue specificity:
Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
Evidence on tissue expression from TISSUES for CCL25 Gene
- Lung(4.2)
- Intestine(3.4)
Primer Products
-
OriGene qPCR primer pairs for CCL25
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCL25 Gene
Orthologs for CCL25 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CCL25 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CCL25 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | CCL25 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Ccl25 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ccl25 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CCL25 35 |
|
OneToOne |
- Species where no ortholog for CCL25 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for CCL25 Gene
(2) SIMAP similar genes for CCL25 Gene using alignment to 3 proteins:
No data available for Paralogs for CCL25 Gene
Variants for CCL25 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000070003 | -- | 8,050,835(+) | GTCAC(A/G)TCCCC | upstream-variant-2KB | |
| rs1000130196 | -- | 8,062,103(+) | TACTC(A/G)GAAAT | intron-variant | |
| rs1000481240 | -- | 8,062,289(+) | CCGTC(A/G)CCCTA | utr-variant-3-prime | |
| rs1000613529 | -- | 8,053,300(+) | GGAGA(C/T)GGAGA | intron-variant | |
| rs1000675719 | -- | 8,052,177(+) | TATAT(C/T)CATAG | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1497112 | CNV | deletion | 17803354 |
| nsv1123216 | CNV | deletion | 24896259 |
| nsv833734 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
81.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.68;
57.19% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CCL25 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CCL25
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCL25 Gene
Disorders for CCL25 Gene
Relevant External Links for CCL25
No disorders were found for CCL25 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCL25 Gene
Publications for CCL25 Gene
- TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development. (PMID: 9285413) Vicari A.P. … Zlotnik A. (Immunity 1997) 2 3 4 22 64
- Identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. (PMID: 10229797) Zaballos A. … Marquez G. (J. Immunol. 1999) 3 4 22 64
- The human CC chemokine TECK (SCYA25) maps to chromosome 19p13.2. (PMID: 9722960) Nomiyama H. … Matsuda Y. (Genomics 1998) 2 3 22 64
- I^-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR. (PMID: 23341447) Watts A.O. … Vischer H.F. (J. Biol. Chem. 2013) 3 4 64
- Abnormal regulation of chemokine TECK and its receptor CCR9 in the endometriotic milieu is involved in pathogenesis of endometriosis by way of enhancing invasiveness of endometrial stromal cells. (PMID: 20081876) Wang Y. … Li D. (Cell. Mol. Immunol. 2010) 3 22 64
Products for CCL25 Gene
- R&D Systems Antibodies for CCL25 (CCL25/TECK)
- R&D Systems Proteins and Enzymes for CCL25 (CCL25/TECK)
- R&D Systems ELISAs, Luminex Assays, and other biochemical assays for CCL25 (CCL25/TECK)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for CCL25
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for CCL25
- Search Origene for MassSpec and Protein Over-expression Lysates for CCL25
- Origene Custom Protein Services for CCL25
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CCL25
- Browse OriGene Inhibitory RNA Products For CCL25
- OriGene qPCR primer pairs for CCL25
- OriGene CRISPR knockouts for CCL25
- OriGene ORF clones in human for CCL25
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CCL25
- GenScript: Next-day shipping cDNA ORF clone for CCL25 in any vector
- GenScript Purified and Recombinant Proteins for CCL25
- GenScript Custom Purified and Recombinant Proteins Services for CCL25
- GenScript Custom Assay Services for CCL25
- GenScript Custom overexpressing Cell Line Services for CCL25
- GenScript: Design CRISPR guide RNA sequences for CCL25
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CCL25
- Sino Biological Human cDNA Clone for CCL25
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for CCL25
- Novus Biologicals proteins and lysates for CCL25
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ProSpec Recombinant Proteins for CCL25
- Cloud-Clone Corp. Antibodies for CCL25
- Cloud-Clone Corp. Proteins for CCL25
- Cloud-Clone Corp Assay Kits for CCL25
- Taconic Biosciences Mouse Models for CCL25
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for CCL25: See all 83
- antibodies-online Kits for CCL25: See all 41
- antibodies-online Proteins for CCL25: See all 47
- Search antibodies-online for peptides
- GeneTex CCL25 antibody for CCL25
- GeneTex Proteins for CCL25
- ViGene Biosciences adenoviral particle packaged cDNA for CCL25 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CCL25 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CCL25 gene
- Search ViGene Biosciences for CCL25
- Santa Cruz Biotechnology (SCBT) Antibodies for CCL25
- Search Santa Cruz Biotechnology (SCBT) for CCL25 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CCL25
- Search for CCL25 Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for CCL25
- Horizon Cell Lines for CCL25
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCL25
- VectorBuilder custom plasmid, inducible vectors for CCL25
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCL25
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CCL25 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer