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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CCL24 Gene

protein-coding   GIFtS: 55
GCID: GC07M075440

chemokine (C-C motif) ligand 24

(Previous names: small inducible cytokine subfamily A (Cys-Cys), member...)
(Previous symbol: SCYA24)
 Explore 38 diseases affiliated with
CCL24 via our new
 Human Malady Compendium 
Biological research products
for CCL24
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Chemokine (C-C Motif) Ligand 241 2     Eosinophil Chemotactic Protein 22 3
MPIF21 2 3 5     Myeloid Progenitor Inhibitory Factor 22 3
SCYA241 2 3 5     Small-Inducible Cytokine A242 3
MPIF-21 2 3     CK-Beta-61
Ckb-61 2     C-C Motif Chemokine 242
Eotaxin-23     Eotaxin-23
Small Inducible Cytokine Subfamily A (Cys-Cys), Member 241 2     

External Ids:    HGNC: 106231   Entrez Gene: 63692   Ensembl: ENSG000001061787   OMIM: 6024955   UniProtKB: O001753   

Export aliases for CCL24 gene to outside databases

Previous GC identifers: GC07M073976 GC07M075039 GC07M075053 GC07M075085 GC07M075279 GC07M070527


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CCL24:
This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in
immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines.
The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on
neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of
colony formation by a multipotential hematopoietic progenitor cell line. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CCL24_HUMAN, O00175
Function: Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but
none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential
hematopoietic progenitor cell line. Binds to CCR3




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007933.15  NT_079595.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CCL24 gene promoter:
         TBP   STAT5B   AP-1   IRF-1   NF-AT   NF-AT4   NF-AT2   NF-AT3   Hlf   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCL24 promoter sequence
   Search SABiosciences Chromatin IP Primers for CCL24

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCL24


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q11.23   Ensembl cytogenetic band:  7q11.23   HGNC cytogenetic band: 7q11.23

CCL24 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCL24 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M075440:  view genomic region     (about GC identifiers)

Start:
75,440,983 bp from pter      End:
75,452,674 bp from pter
Size:
11,692 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 74,774,178-74,776,097     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CCL24_HUMAN, O00175 (See protein sequence)
Recommended Name: C-C motif chemokine 24 precursor  
Size: 119 amino acids; 13134 Da
Subcellular location: Secreted
2 PDB 3D structures from and Proteopedia for CCL24:
1EIG (3D)        1EIH (3D)    
Secondary accessions: B2R5K2

Explore the universe of human proteins at neXtProt for CCL24: NX_O00175

Post-translational modifications:

  • N-glycosylated1
  • View neXtProt modification sites for NX_O00175

  • CCL24 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_002982.2  
    ENSEMBL proteins: 
     ENSP00000222902   ENSP00000400533  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: CCL24
    OriGene Custom Protein Services for CCL24 
    GenScript Purified and Recombinant Proteins for CCL24
    Novus Biologicals CCL24 Proteins
    Novus Biologicals CCL24 Lysates
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for CCL24
    Uscn Proteins for CCL24

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IEA--


    CCL24 for ontologies           About GeneDecksing



    CCL24 Antibody Products: 
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    Uscn ELISAs and CLIAs for CCL24


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CCL24 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001811 Chemokine_IL8-like_dom

    Graphical View of Domain Structure for InterPro Entry O00175

    ProtoNet protein and cluster: O00175

    1 Blocks protein family: IPB000827 Small chemokine

    UniProtKB/Swiss-Prot: CCL24_HUMAN, O00175
    Similarity: Belongs to the intercrine beta (chemokine CC) family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CCL24_HUMAN, O00175
    Function: Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but
    none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential
    hematopoietic progenitor cell line. Binds to CCR3

    miRNA
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    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCL24 (see all 7)
    OriGene shRNA RFP: CCL24
    OriGene siRNA: CCL24
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCL24

    Gene Editing
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCL24 

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    In Situ Assay
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    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CCL24

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005125cytokine activity ----
    GO:0008009chemokine activity IDA10072545


    CCL24 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Ccl24tm1Mer for CCL24
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ccl24):
     hematopoietic system  immune system  respiratory system 

    CCL24 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/9 super-pathways (see all 9About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1PEDF Induced Signaling
    8/12 pathways (see all 12)
    PEDF Induced Signaling1.00
    STAT3 Pathway0.47
    MIF Mediated Glucocorticoid Regulation0.73
    Endothelin-1 Signaling Pathway0.44
    MIF Regulation of Innate Immune Cells0.71
    NFAT Signaling and Lymphocyte Interactions0.37
    IL-6 Pathway0.61
    PGC1Alpha Pathway0.33
    2TGF-Beta Pathway
    TGF-Beta Pathway1.00
    JNK Pathway0.50
    MAPK Family Pathway0.60
    Regulation of eIF4 and p70S6K0.43
    JAK-STAT Pathway0.57
    SOCS Pathway0.29
    3Akt Signaling
    Akt Signaling1.00
    Tec Kinases Signaling0.55
    p38 Signaling0.60
    4Rho Family GTPases
    Rho Family GTPases1.00
    Molecular Mechanisms of Cancer0.51
    ERK Signaling0.61
    5Immune response _CCR3 signaling in eosinophils
    Immune response _CCR3 signaling in eosinophils1.00
    Immune response CCR3 signaling in eosinophils1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for CCL24
        Immune response CCR3 signaling in eosinophils

    5/28 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CCL24 (see all 28)
        Endothelin-1 Signaling Pathway
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C
    NFAT Signaling and Lymphocyte Interactions
    JNK Pathway

    1 GeneGo (Thomson Reuters) Pathway for CCL24
        Immune response CCR3 signaling in eosinophils


    2         Kegg Pathways  (Kegg details for CCL24):
        Cytokine-cytokine receptor interaction
    Chemokine signaling pathway


    CCL24 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CCL24

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    5/18 Interacting proteins for CCL24 (O001753 ENSP000002229024) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCR3P516773, ENSP000003500034I2D: score=1 STRING: ENSP00000350003
    CCR1ENSP000002961404STRING: ENSP00000296140
    CCR10ENSP000003325044STRING: ENSP00000332504
    CCR2ENSP000002923014STRING: ENSP00000292301
    CCR4ENSP000003326594STRING: ENSP00000332659
    About this table

    Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001938positive regulation of endothelial cell proliferation IDA19525930
    GO:0006935chemotaxis TAS9104803
    GO:0006954inflammatory response IEA--
    GO:0006955immune response IEA--
    GO:0007010cytoskeleton organization IDA10072545


    CCL24 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CCL24 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CCL24
    9 Novoseek chemical compound relationships for CCL24 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    rantes 84.7 54 10570327 (4), 11306977 (3), 11467997 (3), 11286614 (3) (see all 29)
    tarc 67.3 4 9794440 (1), 15591886 (1), 11964742 (1)
    ccl3 42.2 2 17350279 (1)
    calcium 13.2 13 10069890 (2), 11237428 (2), 9365122 (1), 9692884 (1) (see all 5)
    actinomycin d 10.1 1 15863444 (1)
    histamine 2.9 1 9182688 (1)
    oxygen 0 7 9692884 (4), 12784909 (1), 11286614 (1)
    steroid 0 1 19522186 (1)
    superoxide 0 1 12192108 (1)

    Search CenterWatch for drugs/clinical trials and news about CCL24 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CCL24 gene: 
    NM_002991.2  

    Unigene Cluster for CCL24:

    Chemokine (C-C motif) ligand 24
    Hs.247838  [show with all ESTs]
    Unigene Representative Sequence: BP338501
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000222902(uc011kga.2) ENST00000416943

    miRNA
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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCL24 (see all 7)
    OriGene shRNA RFP: CCL24
    OriGene siRNA: CCL24
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    Clone
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    Additional cDNA sequence: 

    AJ223461.1 AK312216.1 BC069072.1 BC069391.1 U85768.1 

    1 DOTS entry:

    DT.91821775 

    8 AceView cDNA sequences:

    BP338501 NM_002991 BC069072 BC069391 AJ223461 BP338653 U85768 CB141759 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CCL24 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See CCL24 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CCL24

    SOURCE GeneReport for Unigene cluster: Hs.247838

    UniProtKB/Swiss-Prot: CCL24_HUMAN, O00175
    Tissue specificity: Activated monocytes and activated T lymphocytes

        SABiosciences Expression via Pathway-Focused PCR Arrays including CCL24 (see all 6): 
              Inflammatory Cytokines & Receptors in human mouse rat
              Cytokines & Chemokines in human mouse rat
              Inflammatory Response & Autoimmunity in human mouse rat
              Inflammatory Response & Autoimmunity 384HT in human mouse rat
              Chemokines & Receptors in human mouse rat

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    In Situ
    Assay Products:
     

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CCL24

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CCL24 gene from 1/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkeyp-59a8.16
    si:dkeyp-59a8.26
    (see all 6)
    si:dkeyp-59a8.2
    (see all 6)
    32(a)
    30(a)
    (see all 6)
    many ↔ many
    many ↔ many
    (see all 6)
    20(38282475-38302293)
    20(38304232-38305101)


    ENSEMBL Gene Tree for CCL24 (if available)
    TreeFam Gene Tree for CCL24 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CCL24 gene
    CCL152  CCL162  CCL22  CCL142  CCL4L12  CCL112  CCL72  CCL4L22  
    CCL3L12  CCL52  CCL232  CCL3L32  CCL42  CCL82  CCL132  CCL262  
    CCL32  CCL182  
    18/23 SIMAP similar genes for CCL24 using alignment to 1 protein entry:     CCL24_HUMAN(see all similar genes):
    CCL5    CCL14    CCL3L1    CCL3L3    CCL18    CCL23
    CCL3    CCL4    CCL11    CCL4L2    LOC728835    CCL26
    CCL4L1    CCL13    CCL15    CCL2    CCL7    MCP-3

    CCL24 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/113 NCBI SNPs in CCL24 are shown (see all 113    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs283743871,2
    C,F,--75440666(+) GTGGTG/ACACAC 1 -- ds50014Minor allele frequency- A:0.50NA WA 8
    rs607776061,2
    C,--75440704(+) AGGCAT/CGAGAA 1 -- ds50012Minor allele frequency- C:0.33NA CSA 3
    rs763645451,2
    C,--75440752(+) AGATTG/TTGCCA 1 -- ds50010--------
    rs1384667061,2
    --75440784(+) AGAGCA/GAGACT 1 -- ds50010--------
    rs1492822031,2
    --75440831(+) AACCAA/GGTCAG 1 -- ds50010--------
    rs1434965951,2
    --75440859(+) TTGCCA/CCTGCT 1 -- ds50010--------
    rs114653181,2
    C,F,H,--75440876(-) GAAGAT/ACCCAG 1 -- ds50018Minor allele frequency- A:0.02NA EU NS EA 632
    rs1808301101,2
    --75440908(+) AGGGGC/GCTTGG 1 -- ds50010--------
    rs114653171,2
    C,F,H,--75440940(-) GTTCCC/TGGGGG 1 -- ds50018Minor allele frequency- T:0.01NA EU NS EA WA 624
    rs1169106671,2
    --75440977(+) CATAGA/GAGAGA 1 -- ds50011Minor allele frequency- G:0.01EA 120

    HapMap Linkage Disequilibrium report for CCL24 (75440983 - 75452674 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for CCL24
         2 CNVs: 3686 22956

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCL24
    DNA2.0 Custom Variant and Variant Library Synthesis for CCL24

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CCL24 for disorders           About GeneDecksing

    OMIM gene information: 602495    OMIM disorders: --

    20/38 diseases for CCL24 (see all 38):    About MalaCards
    age related macular degeneration    giant papillary conjunctivitis    vernal keratoconjunctivitis    allergic rhinitis
    papillary conjunctivitis    macular degeneration    keratoconjunctivitis    eosinophilic meningitis
    angiostrongyliasis    eosinophilic esophagitis    acute promyelocytic leukemia    inflammatory bowel disease
    atopic dermatitis    rhinitis    conjunctivitis    eosinophilia
    allergic asthma    ulcerative colitis    asthma    bronchiolitis

    1 disease from the University of Copenhagen DISEASES database for CCL24:
    Asthma

    10/16 Novoseek disease relationships for CCL24 gene (see all 16)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    nasal polyps 64.6 23 19522186 (6), 17438849 (3), 11141953 (2), 16792175 (2) (see all 7)
    eosinophilia 64.3 13 15805998 (2), 15947325 (1), 10415058 (1), 10491000 (1) (see all 6)
    keratoconjunctivitis vernal 62.4 1 12623809 (1)
    asthma 59.5 18 16304252 (3), 17079258 (3), 15207712 (2), 15744457 (2) (see all 10)
    inflammation 55.4 14 16620281 (1), 15805998 (1), 10415058 (1), 12784909 (1) (see all 12)
    airways disease 46.8 5 14698143 (1), 15695929 (1), 19038554 (1)
    allergic reaction 38.4 4 10491000 (1), 12193745 (1), 15480317 (1)
    asthma allergic 37.5 1 19552640 (1)
    polyps 30.1 8 17438849 (4), 11141953 (2), 16792175 (1), 16682802 (1)
    colitis ulcerative 26.3 3 16391516 (2), 11346206 (1)

    Genetic Association Database (GAD): CCL24
    Human Genome Epidemiology (HuGE) Navigator: CCL24 (19 documents)

    Export disorders for CCL24 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CCL24 gene, integrated from 9 sources (see all 151):
    (articles sorted by number of sources associating them with CCL24)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors. (PubMed id 9104803)1, 2, 3, 9 Patel V.P.... Garotta G. (1997)
    2. Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils. (PubMed id 9365122)1, 2, 9 White J.R....Sarau H.M. (1997)
    3. The association of eotaxin-2 and eotaxin-3 gene polymorphisms in a Korean population with ulcerative colitis. (PubMed id 16391516)1, 4, 9 Park Y.R....Chung H.T. (2005)
    4. The suggestive association of eotaxin-2 and eotaxin-3 gene polymorphisms in Korean population with allergic rhinitis. (PubMed id 15580493)1, 4, 9 Chae S.C....Chung H.T. (2005)
    5. NMR solution structure and receptor peptide binding of the CC chemokine eotaxin-2. (PubMed id 10913244)1, 2, 9 Mayer K.L. and Stone M.J. (2000)
    6. Assignment of the human CC chemokine MPIF-2/eotaxin-2 (SCYA24) to chromosome 7q11.23. (PubMed id 9598329)1, 3, 9 Nomiyama H....Yoshie O. (1998)
    7. Association of eotaxin-2 gene polymorphisms with plasma eotaxin-2 concentration. (PubMed id 15744457)1, 4, 9 Min J.W....Shin H.D. (2005)
    8. Analysis of the polymorphisms in eotaxin gene family and their association with asthma, IgE, and eosinophil. (PubMed id 15207712)1, 4, 9 Chae S.C....Chung H.T. (2004)
    9. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6369 HGNC: 10623 AceView: CCL24 Ensembl:ENSG00000106178 euGenes: HUgn6369
    ECgene: CCL24 Kegg: 6369 H-InvDB: CCL24

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CCL24 Pharmacogenomics, SNPs, Pathways
    Wikipedia http://en.wikipedia.org/wiki/CCL24

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CCL24 gene:
    Search GeneIP for patents involving CCL24

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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