Aliases for CCL20 Gene
Aliases for CCL20 Gene
- C-C Motif Chemokine Ligand 20 2 3 5
- Small Inducible Cytokine Subfamily A (Cys-Cys), Member 20 2 3
- Liver And Activation-Regulated Chemokine 3 4
- Macrophage Inflammatory Protein 3 Alpha 3 4
- Chemokine (C-C Motif) Ligand 20 2 3
- Small-Inducible Cytokine A20 3 4
- CC Chemokine LARC 3 4
- MIP-3-Alpha 3 4
- SCYA20 3 4
- MIP3A 3 4
External Ids for CCL20 Gene
- HGNC: 10619
- Entrez Gene: 6364
- Ensembl: ENSG00000115009
- OMIM: 601960
- UniProtKB: P78556
Previous HGNC Symbols for CCL20 Gene
- SCYA20
Previous GeneCards Identifiers for CCL20 Gene
- GC02P226699
- GC02P227410
- GC02P228642
- GC02P228881
- GC02P228504
- GC02P228386
- GC02P228678
- GC02P220520
Summaries for CCL20 Gene
-
This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
GeneCards Summary for CCL20 Gene
CCL20 (C-C Motif Chemokine Ligand 20) is a Protein Coding gene. Diseases associated with CCL20 include Rheumatoid Arthritis and Psoriasis. Among its related pathways are PEDF Induced Signaling and Bacterial infections in CF airways. Gene Ontology (GO) annotations related to this gene include cytokine activity and chemokine activity.
UniProtKB/Swiss-Prot for CCL20 Gene
-
Acts as a ligand for C-C chemokine receptor CCR6. Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed:11352563, PubMed:11035086, PubMed:20068036). The ligand-receptor pair CCL20-CCR6 is responsible for the chemotaxis of dendritic cells (DC), effector/memory T-cells and B-cells and plays an important role at skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathology, including cancer and various autoimmune diseases (PubMed:21376174). CCL20 acts as a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes (PubMed:9038201, PubMed:11352563). Involved in the recruitment of both the proinflammatory IL17 producing helper T-cells (Th17) and the regulatory T-cells (Treg) to sites of inflammation. Required for optimal migration of thymic natural regulatory T cells (nTregs) and DN1 early thymocyte progenitor cells (By similarity). C-terminal processed forms have been shown to be equally chemotactically active for leukocytes (PubMed:11035086). Positively regulates sperm motility and chemotaxis via its binding to CCR6 which triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:23765988, PubMed:25122636). Inhibits proliferation of myeloid progenitors in colony formation assays (PubMed:9129037). May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells (By similarity). Possesses antibacterial activity towards E.coli ATCC 25922 and S.aureus ATCC 29213 (PubMed:12149255).
Additional gene information for CCL20 Gene
- Monarch Initiative
- Search for CCL20 at DataMed
- Search for CCL20 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCL20 Gene
Genomics for CCL20 Gene
GeneHancer (GH) Regulatory Elements for CCL20 Gene
Promoters and enhancers for CCL20 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CCL20 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the CCL20 gene promoter:
Regulatory Element Products
Genomic Locations for CCL20 Gene
Genomic Locations for CCL20 Gene
- chr2:227,813,842-227,817,564
- (GRCh38/hg38)
- Size:
- 3,723 bases
- Orientation:
- Plus strand
- chr2:228,678,558-228,682,280
- (GRCh37/hg19)
Genomic View for CCL20 Gene
Genes around CCL20 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q36.3 by Ensembl
- 2q36.3 by Entrez Gene
- 2q36.3 by HGNC
CCL20 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CCL20 Gene
Proteins for CCL20 Gene
-
Protein details for CCL20 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P78556-CCL20_HUMAN
- Recommended name:
- C-C motif chemokine 20
- Protein Accession:
- P78556
- Q53S51
- Q99664
Protein attributes for CCL20 Gene
- Size:
- 96 amino acids
- Molecular mass:
- 10762 Da
- Quaternary structure:
- No Data Available
Protein Expression for CCL20 Gene
Post-translational modifications for CCL20 Gene
- C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Other Protein References for CCL20 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for CCL20 (CCL20/MIP-3 alpha)
-
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-
Abcam antibodies for CCL20
-
Cloud-Clone Corp. Antibodies for CCL20
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-
Custom Antibody ServicesProSci Antibodies for CCL20
-
Santa Cruz Biotechnology (SCBT) Antibodies for CCL20
- Sino Biological Antibodies for CCL20
Protein Products
- R&D Systems Proteins and Enzymes for CCL20 (CCL20/MIP-3 alpha)
-
OriGene Purified Proteins for CCL20
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-
Cloud-Clone Corp. Proteins for CCL20
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-
ProSci Proteins for CCL20
-
Abcam proteins for CCL20
Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for CCL20
- R&D Systems Proteome Profiler Antibody Arrays, Luminex Assays, ELISAs, and other biochemical assays for CCL20 (CCL20/MIP-3 alpha)
-
Cloud-Clone Corp. Assay Kits for CCL20
-
Abcam assays for CCL20
No data available for DME Specific Peptides for CCL20 Gene
Domains & Families for CCL20 Gene
Gene Families for CCL20 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted secreted proteins
Protein Domains for CCL20 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CCL20 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P78556- Family:
-
- Belongs to the intercrine beta (chemokine CC) family.
Function for CCL20 Gene
Molecular function for CCL20 Gene
- UniProtKB/Swiss-Prot Function:
- Acts as a ligand for C-C chemokine receptor CCR6. Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed:11352563, PubMed:11035086, PubMed:20068036). The ligand-receptor pair CCL20-CCR6 is responsible for the chemotaxis of dendritic cells (DC), effector/memory T-cells and B-cells and plays an important role at skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathology, including cancer and various autoimmune diseases (PubMed:21376174). CCL20 acts as a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes (PubMed:9038201, PubMed:11352563). Involved in the recruitment of both the proinflammatory IL17 producing helper T-cells (Th17) and the regulatory T-cells (Treg) to sites of inflammation. Required for optimal migration of thymic natural regulatory T cells (nTregs) and DN1 early thymocyte progenitor cells (By similarity). C-terminal processed forms have been shown to be equally chemotactically active for leukocytes (PubMed:11035086). Positively regulates sperm motility and chemotaxis via its binding to CCR6 which triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:23765988, PubMed:25122636). Inhibits proliferation of myeloid progenitors in colony formation assays (PubMed:9129037). May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells (By similarity). Possesses antibacterial activity towards E.coli ATCC 25922 and S.aureus ATCC 29213 (PubMed:12149255).
- UniProtKB/Swiss-Prot Induction:
- By bacterial lipopolysaccharides (LPS), TNF and IFNG/IFN-gamma. Induced by phorbol myristate acetate (PMA) in U-937 cell line and bowes melanoma. Repressed by IL10/interleukin-10.
Phenotypes From GWAS Catalog for CCL20 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005125 | cytokine activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 17703191 |
| GO:0008009 | chemokine activity | TAS,IBA | -- |
| GO:0031731 | CCR6 chemokine receptor binding | IDA,IEA | 12081481 |
Phenotypes for CCL20 Gene
- GenomeRNAi human phenotypes for CCL20:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCL20
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CCL20 gene
-
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- Search ViGene Biosciences for CCL20
CRISPR Products
-
OriGene CRISPR knockouts for CCL20
- genomics-online: gRNA clones - Search results for 133 available CD45R0 gene related products
- Overview of 133 available CD45R0 gene related products
- Applied Biological Materials CRISPR for CCL20
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCL20
- GenScript: Design CRISPR guide RNA sequences for CCL20
miRNA for CCL20 Gene
- miRTarBase miRNAs that target CCL20
miRNA Products
- Search ViGene Biosciences for CCL20
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CCL20
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- Overview of 133 available CD45R0 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CCL20 gene
Clone Products
- Sino Biological Human cDNA Clone for CCL20
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CCL20
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCL20
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for CCL20
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for CCL20
-
ViGene Biosciences adenoviral particle packaged cDNA for CCL20 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CCL20 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CCL20 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCL20 Gene
Localization for CCL20 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CCL20 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| plasma membrane | 2 |
| nucleus | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| cytosol | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005615 | extracellular space | TAS,IBA | -- |
| GO:0005622 | intracellular | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CCL20 Gene
Pathways & Interactions for CCL20 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | PEDF Induced Signaling |
.61
|
.47
|
| 2 | TGF-Beta Pathway |
.60
.57
|
.51
.40
|
| 3 | Peptide ligand-binding receptors | ||
| 4 | Akt Signaling |
.60
.60
|
|
| 5 | ERK Signaling |
.61
|
|
Pathways by source for CCL20 Gene
1 BioSystems pathway for CCL20 Gene
12 Reactome pathways for CCL20 Gene
5 KEGG pathways for CCL20 Gene
2 GeneGo (Thomson Reuters) pathways for CCL20 Gene
1 R&D Systems pathway for CCL20 Gene
27 Qiagen pathways for CCL20 Gene
Interacting Proteins for CCL20 Gene
Selected Interacting proteins:
P78556-CCL20_HUMAN
ENSP00000351671
for CCL20 Gene via
MINT
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002548 | monocyte chemotaxis | IBA | -- |
| GO:0006935 | chemotaxis | TAS,IDA | 20068036 |
| GO:0006954 | inflammatory response | TAS,IBA | -- |
| GO:0006955 | immune response | TAS | 10521347 |
| GO:0007165 | signal transduction | TAS | 9038201 |
No data available for SIGNOR curated interactions for CCL20 Gene
Transcripts for CCL20 Gene
mRNA/cDNA for CCL20 Gene
- (2) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (76) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CCL20 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CCL20
- genomics-online: gRNA clones - Search results for 133 available CD45R0 gene related products
- Overview of 133 available CD45R0 gene related products
- Applied Biological Materials CRISPR for CCL20
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCL20
- GenScript: Design CRISPR guide RNA sequences for CCL20
miRNA Products
- Search ViGene Biosciences for CCL20
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CCL20
- Browse OriGene Inhibitory RNA Products For CCL20
- genomics-online: shRNA clones - Search results for 133 available CD45R0 gene related products
- Overview of 133 available CD45R0 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CCL20 gene
Clone Products
- Sino Biological Human cDNA Clone for CCL20
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CCL20
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCL20
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for CCL20
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||
| SP2: | - | ||||||||||
| SP3: |
Expression for CCL20 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Epiblast (Early Embryonic Tissues)
- Epiblast Cells Epiblast
- Mesenchymal Stem Cells (Uncategorized)
- Umbilical Cord (Extraembryonic Tissues)
- Bone (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
- Lung (Respiratory System)
-
Colon (Gastrointestinal Tract)
-
Tonsil (Hematopoietic System)
mRNA differential expression in normal tissues according to GTEx for CCL20 Gene
This gene is overexpressed in Minor Salivary Gland (x12.4), Lung (x6.9), and Liver (x5.5).
This gene is overexpressed in Islet of Langerhans (30.9), Pancreas (23.1), and Plasma (14.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CCL20 Gene
NURSA nuclear receptor signaling pathways regulating expression of CCL20 Gene:
CCL20SOURCE GeneReport for Unigene cluster for CCL20 Gene:
Hs.75498mRNA Expression by UniProt/SwissProt for CCL20 Gene:
P78556-CCL20_HUMAN
Tissue specificity:
Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level). Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon.
Evidence on tissue expression from TISSUES for CCL20 Gene
- Liver(4.4)
- Pancreas(4.2)
- Intestine(3.4)
- Lymph node(2.9)
- Blood(2.6)
- Lung(2.6)
- Spleen(2.5)
- Skin(2.3)
- Gall bladder(2.1)
Primer Products
-
OriGene qPCR primer pairs for CCL20
-
OriGene qPCR primer pairs and template standards for CCL20
- genomics-online: primer clones - Search results for 133 available CD45R0 gene related products
- Overview of 133 available CD45R0 gene related products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for CCL20 Gene
Orthologs for CCL20 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CCL20 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | CCL20 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | CCL20 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Ccl20 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ccl20 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | CCL20 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | CCL20 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CCL20 33 |
|
||
| MIP-3ALPHA 34 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | CCL20 34 |
|
OneToOne |
- Species where no ortholog for CCL20 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for CCL20 Gene
(18) SIMAP similar genes for CCL20 Gene using alignment to 1 proteins:
No data available for Paralogs for CCL20 Gene
Variants for CCL20 Gene
| SNP ID | Clin | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000637413 | -- | 227,817,189(+) | C/G | 3_prime_UTR_variant | |
| rs1000749225 | -- | 227,812,991(+) | T/C | upstream_transcript_variant | |
| rs1000877730 | -- | 227,815,286(+) | G/A | intron_variant | |
| rs1001591137 | -- | 227,817,907(+) | C/T | downstream_transcript_variant | |
| rs1001622432 | -- | 227,817,579(+) | T/A | downstream_transcript_variant |
Residual Variation Intolerance Score:
66.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.24;
5.42% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CCL20 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CCL20
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCL20 Gene
Disorders for CCL20 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| rheumatoid arthritis |
|
|
| psoriasis |
|
|
| inflammatory bowel disease |
|
|
| bejel |
|
|
| pustulosis palmaris et plantaris |
|
|
Search CCL20 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CCL20
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for CCL20 Gene
Publications for CCL20 Gene
- Genomic organization of the CC chemokine mip-3alpha/CCL20/larc/exodus/SCYA20, showing gene structure, splice variants, and chromosome localization. (PMID: 11352563) Nelson RT … McColl SR (Genomics 2001) 2 3 4 22 58
- Molecular cloning of a novel human CC chemokine liver and activation-regulated chemokine (LARC) expressed in liver. Chemotactic activity for lymphocytes and gene localization on chromosome 2. (PMID: 9038201) Hieshima K … Nomiyama H (The Journal of biological chemistry 1997) 2 3 4 22 58
- The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins. (PMID: 12149255) Hoover DM … Lubkowski J (The Journal of biological chemistry 2002) 3 4 22 58
- Regulated production and molecular diversity of human liver and activation-regulated chemokine/macrophage inflammatory protein-3 alpha from normal and transformed cells. (PMID: 11035086) Schutyser E … Van Damme J (Journal of immunology (Baltimore, Md. : 1950) 2000) 3 4 22 58
- A role for the chemokine receptor CCR6 in mammalian sperm motility and chemotaxis. (PMID: 23765988) Caballero-Campo P … Gerton GL (Journal of cellular physiology 2014) 3 4 58
Products for CCL20 Gene
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- Cloud-Clone Corp. disease models service
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- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCL20
- VectorBuilder custom plasmid, inducible vectors for CCL20
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCL20
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 232 available CCL20 Antibodies ranked by validation data
- Compare Top CCL20 Antibodies
- antibodies-online: Search results for 96 available CCL20 Elisa Kits ranked by validation data
- Compare Top CCL20 Elisa Kits
- antibodies-online: Search results for 84 available CCL20 Proteins ranked by validation data
- Compare Top CCL20 Proteins
- GeneTex CCL20 antibody for CCL20
- GeneTex Proteins for CCL20
- ViGene Biosciences adenoviral particle packaged cDNA for CCL20 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CCL20 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CCL20 gene
- Search ViGene Biosciences for CCL20
- Santa Cruz Biotechnology (SCBT) Antibodies for CCL20
- Search Santa Cruz Biotechnology (SCBT) for CCL20 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CCL20
- Custom Antibody ServicesProSci Antibodies for CCL20
- ProSci Proteins for CCL20
- Horizon Cell Lines for CCL20
- genomics-online: cdna clones - Search results for 133 available CCL20 gene related products
- Overview of 133 available CCL20 gene related products
- orf clones - Search results for 133 available CCL20 gene related products
- Overview of 133 available CCL20 gene related products
- genomics-online: gRNA clones - Search results for 133 available CCL20 gene related products
- Overview of 133 available CCL20 gene related products
- genomics-online: primer clones - Search results for 133 available CCL20 gene related products
- Overview of 133 available CCL20 gene related products
- genomics-online: shRNA clones - Search results for 133 available CCL20 gene related products
- Overview of 133 available CCL20 gene related products
Sources for CCL20 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew