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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CCL20 Gene

protein-coding   GIFtS: 62
GCID: GC02P228678

chemokine (C-C motif) ligand 20

(Previous names: small inducible cytokine subfamily A (Cys-Cys), member...)
(Previous symbol: SCYA20)
 Explore 71 diseases affiliated with
CCL20 via our new
 Human Malady Compendium 
Biological research products
for CCL20
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Chemokine (C-C Motif) Ligand 201 2     Macrophage Inflammatory Protein 3 Alpha2 3
LARC1 2 3 5     Small-Inducible Cytokine A202 3
SCYA201 2 3 5     MIP-3-Alpha1
MIP3A2 3 5     CC Chemokine LARC2 3
CKb41 2     Exodus-11
MIP-3a1 2     Beta Chemokine Exodus-12
ST381 2     C-C Motif Chemokine 202
Small Inducible Cytokine Subfamily A (Cys-Cys), Member 201 2     Beta-Chemokine Exodus-13
Liver And Activation-Regulated Chemokine2 3     

External Ids:    HGNC: 106191   Entrez Gene: 63642   Ensembl: ENSG000001150097   OMIM: 6019605   UniProtKB: P785563   

Export aliases for CCL20 gene to outside databases

Previous GC identifers: GC02P226699 GC02P227410 GC02P228642 GC02P228881 GC02P228504 GC02P228386 GC02P220520


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CCL20_HUMAN, P78556
Function: Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits
proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the
mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed
forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli
ATCC 25922 and S.aureus ATCC 29213

Gene Wiki entry for CCL20


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CCL20 gene promoter:
         HFH-3   Pax-5   Nkx2-2   NF-kappaB   E47   C/EBPalpha   FOXI1   Chx10   NF-kappaB1   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCL20 promoter sequence
   Search SABiosciences Chromatin IP Primers for CCL20

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCL20


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q36.3   Ensembl cytogenetic band:  2q36.3   HGNC cytogenetic band: 2q36.3

CCL20 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCL20 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P228678:  view genomic region     (about GC identifiers)

Start:
228,678,558 bp from pter      End:
228,682,280 bp from pter
Size:
3,723 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CCL20_HUMAN, P78556 (See protein sequence)
Recommended Name: C-C motif chemokine 20 precursor  
Size: 96 amino acids; 10762 Da
Subunit: Binds to and activate CCR6
Subcellular location: Secreted
3 PDB 3D structures from and Proteopedia for CCL20:
1M8A (3D)        2HCI (3D)        2JYO (3D)    
Secondary accessions: Q53S51 Q99664
Alternative splicing: 2 isoforms:  P78556-1   P78556-2   

Explore the universe of human proteins at neXtProt for CCL20: NX_P78556

Post-translational modifications:

  • C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from
  • peripheral blood monocytes1
  • View neXtProt modification sites for NX_P78556

  • CCL20 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001123518.1  NP_004582.1  

    ENSEMBL proteins: 
     ENSP00000386273   ENSP00000351671  
    Reactome Protein details: P78556
    Human Recombinant Protein Products: 
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    ProSpec Recombinant Protein for CCL20
    Browse Proteins at Uscn

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space IEA--


    CCL20 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CCL20 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR000827 Chemokine_CC_CS
     IPR001811 Chemokine_IL8-like_dom

    Graphical View of Domain Structure for InterPro Entry P78556

    ProtoNet protein and cluster: P78556

    1 Blocks protein family: IPB000827 Small chemokine

    UniProtKB/Swiss-Prot: CCL20_HUMAN, P78556
    Similarity: Belongs to the intercrine beta (chemokine CC) family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CCL20_HUMAN, P78556
    Function: Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits
    proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the
    mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed
    forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli
    ATCC 25922 and S.aureus ATCC 29213
    Induction: By bacterial lipopolysaccharides (LPS), TNF and IFNG/IFN-gamma. Induced by phorbol myristate acetate (PMA)
    in U-937 cell line and bowes melanoma. Repressed by IL10/interleukin-10

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCL20

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005125cytokine activity ----
    GO:0005515protein binding ----
    GO:0008009chemokine activity IEA--


    CCL20 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for CCL20:
     Increased cell number in G2M,  


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/14 super-pathways (see all 14About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1PEDF Induced Signaling
    8/12 pathways (see all 12)
    PEDF Induced Signaling1.00
    STAT3 Pathway0.47
    MIF Mediated Glucocorticoid Regulation0.73
    Endothelin-1 Signaling Pathway0.44
    MIF Regulation of Innate Immune Cells0.71
    NFAT Signaling and Lymphocyte Interactions0.37
    IL-6 Pathway0.61
    PGC1Alpha Pathway0.33
    2TGF-Beta Pathway
    TGF-Beta Pathway1.00
    JNK Pathway0.50
    MAPK Family Pathway0.60
    Regulation of eIF4 and p70S6K0.43
    JAK-STAT Pathway0.57
    SOCS Pathway0.29
    3Class A/1 (Rhodopsin-like receptors)
    Class A/1 (Rhodopsin-like receptors)1.00
    Peptide ligand-binding receptors0.61
    GPCR ligand binding0.75
    G alpha (i) signalling events0.44
    4Akt Signaling
    Akt Signaling1.00
    Tec Kinases Signaling0.55
    p38 Signaling0.60
    5Rho Family GTPases
    Rho Family GTPases1.00
    Molecular Mechanisms of Cancer0.51
    ERK Signaling0.61

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for CCL20
        Immune response Toll-like receptor (TLR) ligands and common TLR signaling pathway leading to cell proinflammatory response

    5/27 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CCL20 (see all 27)
        Endothelin-1 Signaling Pathway
    Molecular Mechanisms of Cancer
    Antioxidant Action of Vitamin-C
    NFAT Signaling and Lymphocyte Interactions
    JNK Pathway

    2 GeneGo (Thomson Reuters) Pathways for CCL20
        Immune response TLR signaling pathways
    Bacterial infections in CF airways

    1 BioSystems Pathway for CCL20 
        EBV LMP1 signaling

    5/8        Reactome Pathways for CCL20 (see all 8)
        GPCR downstream signaling
    Peptide ligand-binding receptors
    Chemokine receptors bind chemokines
    Signal Transduction
    Signaling by GPCR


    3         Kegg Pathways  (Kegg details for CCL20):
        Cytokine-cytokine receptor interaction
    Chemokine signaling pathway
    Rheumatoid arthritis


    CCL20 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CCL20

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/158 Interacting proteins for CCL20 (P785562, 3 ENSP000003516714) via UniProtKB, MINT, STRING, and/or I2D (see all 158)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRAF6Q9Y4K32, 3MINT-6505246 I2D: score=1 
    RALBP1Q153112, 3, ENSP000000193174MINT-5226611 MINT-6505265 I2D: score=1 STRING: ENSP00000019317
    CCR6P516843, ENSP000003393934I2D: score=3 STRING: ENSP00000339393
    VCANP136113, ENSP000002650774I2D: score=3 STRING: ENSP00000265077
    CTSBP078583I2D: score=1 
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006935chemotaxis IEA--
    GO:0006954inflammatory response IEA--
    GO:0006955immune response IEA--
    GO:0007165signal transduction TAS9038201
    GO:0007267cell-cell signaling TAS9038201


    CCL20 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CCL20 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CCL20
    10/20 Novoseek chemical compound relationships for CCL20 gene (see all 20)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    larc 95.7 108 9038201 (8), 9169459 (8), 12239608 (7), 10064080 (6) (see all 32)
    mip-3alpha 86.4 9 15069060 (7), 11352563 (1), 17928889 (1)
    tarc 76.2 12 9365118 (3), 9153236 (1), 12799214 (1), 11001915 (1) (see all 9)
    ccl3 76.1 11 18565769 (2), 18625197 (1), 19001077 (1), 17369706 (1) (see all 9)
    rantes 68.8 25 18492658 (3), 11022002 (2), 11160208 (1), 11797102 (1) (see all 22)
    ccl4 60 15 18565769 (2), 18625197 (1), 19120450 (1), 17369706 (1) (see all 13)
    flagellin 51.8 8 15069060 (3), 19814810 (2), 11717433 (1), 20471126 (1) (see all 5)
    il-12 43.4 1 15860229 (1)
    poly(i-c) 33 1 16911361 (1)
    imac 32 7 16034074 (4)

    Search CenterWatch for drugs/clinical trials and news about CCL20 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CCL20 gene (2 alternative transcripts): 
    NM_001130046.1  NM_004591.2  

    Unigene Cluster for CCL20:

    Chemokine (C-C motif) ligand 20
    Hs.75498  [show with all ESTs]
    Unigene Representative Sequence: BC020698
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000409189(uc002vpl.2 uc002vpm.2) ENST00000489160 ENST00000358813
    ENST00000473642

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    Additional cDNA sequence: 

    BC020698.1 D86955.1 U64197.1 U77035.1 

    5 DOTS entries:

    DT.211225  DT.95102901  DT.100777315  DT.91717429  DT.100777317 

    24/76 AceView cDNA sequences (see all 76):

    AA297433 AA983599 D17012 BM833314 AW965098 AW168095 D17181 CD640247 
    BM955557 BM955559 BG534134 CD523297 CD521287 CD641783 AA514362 AI285199 
    AI718638 D86955 BM956129 BM955558 U77035 AU185348 NM_004591 AW084987 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for CCL20    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b
    SP1:              -                     
    SP2:              -                     
    SP3:                                    


    ECgene alternative splicing isoforms for CCL20

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CCL20 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAGGGTTTAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    CCL20 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ mesenchymal Progenitor SK11 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See CCL20 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CCL20

    SOURCE GeneReport for Unigene cluster: Hs.75498

    UniProtKB/Swiss-Prot: CCL20_HUMAN, P78556
    Tissue specificity: Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and
    fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon

        SABiosciences Expression via Pathway-Focused PCR Arrays including CCL20 (see all 8): 
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              Inflammatory Response & Autoimmunity 384HT in human mouse rat
              Antigen Presenting Cells in human mouse rat
              Th17 Response in human mouse rat
              Inflammatory Cytokines & Receptors in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCL20

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CCL20 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccl201 , 5 chemokine (C-C motif) ligand 201, 5 72.98(n)1
    64.21(a)1
      1 (42.69 cM)5
    202971  NM_016960.21  NP_058656.11 
     831167665 
    chicken
    (Gallus gallus)
    Aves CCL201 chemokine (C-C motif) ligand 20 61.65(n)
    55.91(a)
      395082  NM_204438.1  NP_989769.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ccl206
    zgc:1952096
    zgc:195209
    32(a)
    30(a)
    many → 1
    many → 1
    24(26803332-26806214)
    2(45241704-45243634)


    ENSEMBL Gene Tree for CCL20 (if available)
    TreeFam Gene Tree for CCL20 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/134 NCBI SNPs in CCL20 are shown (see all 134    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1838241781,2
    --228676559(+) GTTGGC/TCAGGT 2 -- us2k10--------
    rs784997631,2
    C,F,--228676591(+) CGGCTC/TGCCGT 2 -- us2k11Minor allele frequency- T:0.08EA 120
    rs101796001,2
    C,F,H,--228676594(+) CTCGCC/TGTAAC 2 -- us2k113Minor allele frequency- T:0.35NS EA NA WA CSA 784
    rs1460017321,2
    --228676769(+) CACCTC/TGGCCT 2 -- us2k10--------
    rs1892745961,2
    --228676770(+) ACCTCA/GGCCTC 2 -- us2k10--------
    rs1486805811,2
    --228676796(+) TACAGG/TCATGA 2 -- us2k10--------
    rs1150855381,2
    F,--228676856(+) CTTTCT/CGTCTG 2 -- us2k11Minor allele frequency- C:0.04WA 118
    rs621900051,2
    C,--228676922(+) CAGTCG/AGTTTA 2 -- us2k15Minor allele frequency- A:0.24NA WA EA 362
    rs1925789321,2
    --228676974(+) CCTAGA/GGAACA 2 -- us2k10--------
    rs1851337991,2
    --228676976(+) TAGAGA/TACATT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for CCL20 (228678558 - 228682280 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for CCL20
         1 CNV: 32395

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCL20
    DNA2.0 Custom Variant and Variant Library Synthesis for CCL20

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CCL20 for disorders           About GeneDecksing

    OMIM gene information: 601960    OMIM disorders: --

    20/71 diseases for CCL20 (see all 71):    About MalaCards
    middle ear cholesteatoma    inflammatory bowel disease    hordeolum    chronic obstructive pulmonary disease
    smallpox    intrauterine infections    obstructive jaundice    acute liver failure
    cystic fibrosis    allergic rhinitis    peripheral t-cell lymphoma    cholesteatoma
    atopic dermatitis    jaundice    rheumatoid arthritis    pulmonary disease
    hepatitis c    periodontal disease    ulcerative colitis    viral hepatitis

    3 diseases from the University of Copenhagen DISEASES database for CCL20:
    Psoriasis     Hordeolum     Inflammatory bowel disease

    10/32 Novoseek disease relationships for CCL20 gene (see all 32)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    inflammation 57.2 25 17272517 (3), 16215992 (2), 10974036 (2), 12821122 (1) (see all 19)
    necrosis 56.7 34 16232215 (1), 17068485 (1), 18492658 (1), 16045736 (1) (see all 32)
    inflammatory bowel diseases 49.3 11 12427784 (4), 14997037 (1), 16306769 (1), 17272517 (1) (see all 7)
    psoriasis 48.2 14 15315354 (3), 15315355 (2), 19295614 (2), 10843722 (1) (see all 5)
    tumors 38.9 63 19340288 (5), 15470034 (3), 15652956 (3), 18465142 (2) (see all 37)
    dermatitis atopic 35.6 2 11133838 (1), 17369706 (1)
    rheumatoid arthritis 34.1 10 19535263 (2), 17619881 (2), 17133360 (2), 19797510 (1) (see all 7)
    colitis ulcerative 30.1 4 12427784 (2), 16306769 (1), 18340639 (1)
    pathological processes 22.7 1 12356943 (1)
    skin lesion 19.9 2 15315355 (1), 19659772 (1)

    Human Genome Epidemiology (HuGE) Navigator: CCL20 (9 documents)

    Export disorders for CCL20 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CCL20 gene, integrated from 9 sources (see all 348) (see top 10):
    (articles sorted by number of sources associating them with CCL20)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of a novel human CC chemokine liver and activation- regulated chemokine (LARC) expressed in liver. Chemotactic activity for lymphocytes and gene localization on chromosome 2. (PubMed id 9038201)1, 2, 3, 9 Hieshima K.... Nomiyama H. (1997)
    2. Genomic organization of the CC chemokine mip-3alpha/CCL20/larc/ exodus/SCYA20, showing gene structure, splice variants, and chromosome localization. (PubMed id 11352563)1, 2, 3, 9 Nelson R.T.... McColl S.R. (2001)
    3. The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins. (PubMed id 12149255)1, 2, 9 Hoover D.M....Lubkowski J. (2002)
    4. Regulated production and molecular diversity of human liver and activation-regulated chemokine/macrophage inflammatory protein-3 alpha from normal and transformed cells. (PubMed id 11035086)1, 2, 9 Schutyser E.... Van Damme J. (2000)
    5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3beta. (PubMed id 9013939)1, 2 Rossi D.L.... Zlotnik A. (1997)
    8. Cloning and characterization of Exodus, a novel beta-chemokine. (PubMed id 9129037)1, 2 Hromas R.A.... Klemsz M.J. (1997)
    9. Proinflammatory cytokines synergistically enhance the production of chemokine ligand 20 (CCL20) from rheumatoid fibroblast-like syno vial cells in vitro and serum CCL20 is reduced in vivo by biologic disease-modi fying antirheumatic drugs. (PubMed id 19797510)1, 9 Kawashiri S.Y....Eguchi K. (2009)
    10. Macrophage inflammatory protein-3alpha is a novel serum marker for nasopharyngeal carcinoma detection and prediction of treatment outcomes. (PubMed id 18980993)1, 9 Chang K.P....Yu J.S. (2008)
    11. CCL20 chemokine induces both osteoblast proliferation and osteoclast differentiation: Increased levels of CCL20 are expressed in subchondral bone tissue of rheumatoid arthritis patients. (PubMed id 17133360)1, 9 Lisignoli G....Facchini A. (2007)
    12. Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells. (PubMed id 16215992)1, 9 Brand S....Dambacher J. (2006)
    13. Selective early production of CCL20, or macrophage inflammatory protein 3alpha, by human mast cells in response to Pseudomonas aeruginosa. (PubMed id 12496186)1, 9 Lin T.J....Marshall J.S. (2003)
    14. Increased serum levels of macrophage inflammatory protein-3alpha in hepatocellular carcinoma: relationship with clinical factors and prognostic importance during therapy. (PubMed id 12684696)1, 9 Yamauchi K....Onji M. (2003)
    15. Production of macrophage inflammatory protein-3alpha in human follicular fluid and cultured granulosa cells. (PubMed id 15474097)1, 9 Kawano Y....Miyakawa I. (2004)
    16. Prolactin enhances basal and IL-17-induced CCL20 production by human keratinocytes. (PubMed id 19350575)1, 9 Kanda N....Watanabe S. (2009)
    17. Hypoxic synovial environment and expression of macrophage inflammatory protein 3gamma/CCL20 in juvenile idiopathic arthritis. (PubMed id 18512817)1, 9 Bosco M.C....Varesio L. (2008)
    18. Physiological role of macrophage inflammatory protein-3 alpha induction during maturation of intestinal macrophages. (PubMed id 16034074)1, 9 Hausmann M....Rogler G. (2005)
    19. Colonic epithelial cells are a major site of macrophage inflammatory protein 3alpha (MIP-3alpha) production in normal colon and inflammatory bowel disease. (PubMed id 12427784)1, 9 Kwon J.H....Keates A.C. (2002)
    20. Expression of lymphocyte-specific chemokines in human malignant glioma: Essential role of LARC in cellular immunity of malignant glioma. (PubMed id 12239608)1, 9 Kimura T....Ushio Y. (2002)
    21. Identification of CCR6, the specific receptor for a novel lymphocyte- directed CC chemokine LARC. (PubMed id 9169459)1, 9 Baba M.... Yoshie O. (1997)
    22. Interaction between CXCR4 and CCL20 pathways regulates tumor growth. (PubMed id 19340288)1, 9 Beider K....Peled A. (2009)
    23. Chlamydophila pneumoniae triggers release of CCL20 an d vascular endothelial growth factor from human bronchial epithelial cells thro ugh enhanced intracellular oxidative stress and MAPK activation. (PubMed id 19479364)1, 9 Kim T.B....Cho Y.S. (2009)
    24. Human macrophage inflammatory protein 3alpha: protein and peptide nuclear magnetic resonance solution structures, dimerization, dynamics, and anti-infective properties. (PubMed id 18086840)1, 9 Chan D.I....Vogel H.J. (2008)
    25. Macrophage inflammatory protein-3alpha and beta-defensin-2 stimulate dentin sialophosphoprotein gene expression in human pulp cells. (PubMed id 12821122)1, 9 Shiba H....Kurihara H. (2003)
    26. Induction of CCL20 production by Kaposi sarcoma-assoc iated herpesvirus: role of viral FLICE inhibitory protein K13-induced NF-kappaB activation. (PubMed id 19324905)1, 9 Punj V....Chaudhary P.M. (2009)
    27. Seminal plasma promotes the attraction of Langerhans cells via the secretion of CCL20 by vaginal epithelial cells: involvement in the sexual transmission of HIV. (PubMed id 16531471)1, 9 Berlier W....Delezay O. (2006)
    28. MEK is a key modulator for TLR5-induced interleukin-8 and MIP3alpha gene expression in non-transformed human colonic epithelial cells. (PubMed id 15069060)1, 9 Rhee S.H....Pothoulakis C. (2004)
    29. ESE-1, an enterocyte-specific Ets transcription factor, regulates MIP-3alpha gene expression in Caco-2 human colonic epithelial cells. (PubMed id 12414801)1, 9 Kwon J.H....Keates A.C. (2003)
    30. Selective expression of liver and activation-regulated chemokine (LARC) in intestinal epithelium in mice and humans. (PubMed id 10064080)1, 9 Tanaka Y....Yoshie O. (1999)
    31. Upregulation of CCL20 and recruitment of CCR6+ gastric infiltrating lymphocytes in Helicobacter pylori gastritis. (PubMed id 17562763)1, 9 Wu Y.Y....Hsu P.N. (2007)
    32. A functional role for interleukin-21 in promoting the synthesis of the T-cell chemoattractant, MIP-3alpha, by gut epithelial cells. (PubMed id 17241869)1, 9 Caruso R....Monteleone G. (2007)
    33. Extracellular nucleotides regulate CCL20 release from human primary airway epithelial cells, monocytes and monocyte-derived dendritic cells. (PubMed id 17295217)1, 9 Marcet B....Communi D. (2007)
    34. Expression of macrophage inflammatory protein-3alpha in an endometrial epithelial cell line, HHUA, and cultured human endometrial stromal cells. (PubMed id 12356943)1, 9 Sun B....Miyakawa I. (2002)
    35. Increased serum levels of macrophage inflammatory protein-3alpha in chronic viral hepatitis: prognostic importance of macrophage inflammatory protein-3alpha during interferon therapy in chronic hepatitis C. (PubMed id 12010510)1, 9 Yamauchi K....Onji M. (2002)
    36. Macrophage inflammatory protein 3alpha is involved in the constitutive trafficking of epidermal langerhans cells. (PubMed id 10601351)1, 9 Charbonnier A.S....Maurer D. (1999)
    37. CCL20/CCR6 expression profile in pancreatic cancer. (PubMed id 20459729)1, 9 Rubie C....Schilling M.K. (2010)
    38. Enhanced expression of CCL20 in human Helicobacter pylori-associated gastritis. (PubMed id 19006683)1, 9 Yoshida A....Kohno S. (2009)
    39. Adipocyte culture medium stimulates invasiveness of M DA-MB-231 cell via CCL20 production. (PubMed id 19885605)1, 9 Kim K.Y....Yang Y. (2009)
    40. Macrophage-inflammatory protein-3alpha mediates epidermal growth factor receptor transactivation and ERK1/2 MAPK signaling in Caco-2 colonic epithelial cells via metalloproteinase-dependent release of amphiregulin. (PubMed id 17548638)1, 9 Keates S....Keates A.C. (2007)
    41. BCR ligation reprograms B cells for migration to the T zone and B-cell follicle sequentially. (PubMed id 11877260)1, 9 Casamayor-Palleja M....Defrance T. (2002)
    42. Differentiated keratinocytes are responsible for TNF-alpha regulated production of macrophage inflammatory protein 3alpha/CCL20, a potent chemokine for Langerhans cells. (PubMed id 11532377)1, 9 Tohyama M....Hashimoto K. (2001)
    43. Regulation of the psoriatic chemokine CCL20 by E3 lig ases Trim32 and Piasy in keratinocytes. (PubMed id 20054338)1, 9 Liu Y....Kulesz-Martin M.F. (2010)
    44. Enhanced expression and clinical significance of CC-chemokine MIP-3 alpha in hepatocellular carcinoma. (PubMed id 16764701)1, 9 Rubie C....Schilling M. (2006)
    45. Chemokine expression in hepatocellular carcinoma versus colorectal liver metastases. (PubMed id 17075975)1, 9 Rubie C....Schilling M. (2006)
    46. Induction of cytokine (interleukin-1alpha and tumor necrosis factor-alpha) and chemokine (CCL20, CCL27, and CXCL8) alarm signals after allergen and irritant exposure. (PubMed id 15679580)1, 9 Spiekstra S.W....Gibbs S. (2005)
    47. Cloning and characterization of a specific receptor for the novel CC chemokine MIP-3alpha from lung dendritic cells. (PubMed id 9294137)1, 9 Power C.A....Wells T.N. (1997)
    48. CCL20/CCR6 chemokine/receptor expression in bone tiss ue from osteoarthritis and rheumatoid arthritis patients: different response of osteoblasts in the two groups. (PubMed id 19492413)1, 9 Lisignoli G....Facchini A. (2009)
    49. HIV type 1 glycoprotein 120 inhibits human B cell che motaxis to CXC chemokine ligand (CXCL) 12, CC chemokine ligand (CCL)20, and CCL 21. (PubMed id 15972662)1, 9 Badr G....Richard Y. (2005)
    50. Calcium triggers beta-defensin (hBD-2 and hBD-3) and chemokine macrophage inflammatory protein-3 alpha (MIP-3alpha/CCL20) expression in monolayers of activated human keratinocytes. (PubMed id 14714554)1, 9 Pernet I....Viac J. (2003)
    51. Inducible expression of a CC chemokine liver- and activation-regulated chemokine (LARC)/macrophage inflammatory protein (MIP)-3 alpha/CCL20 by epidermal keratinocytes and its role in atopic dermatitis. (PubMed id 11133838)1, 9 Nakayama T....Yoshie O. (2001)
    52. Cutting edge: immature dendritic cells generated from monocytes in the presence of TGF-beta 1 express functional C-C chemokine receptor 6. (PubMed id 10438902)1, 9 Yang D....Oppenheim J.J. (1999)
    53. STRL22 is a receptor for the CC chemokine MIP-3alpha. (PubMed id 9223454)1, 9 Liao F....Farber J.M. (1997)
    54. Modulation of expression of innate immunity markers C XCL5/ENA-78 and CCL20/MIP3alpha by protease-activated receptors (PARs) in human gingival epithelial cells. (PubMed id 19567485)1, 9 Rohani M.G....Chung W.O. (2010)
    55. CCR6 regulation of the actin cytoskeleton orchestrates human beta defensin-2- and CCL20-mediated restitution of colonic epithelial cells. (PubMed id 19233848)1, 9 Vongsa R.A....Dwinell M.B. (2009)
    56. Th17 cytokines stimulate CCL20 expression in keratino cytes in vitro and in vivo: implications for psoriasis pathogenesis. (PubMed id 19295614)1, 9 Harper E.G....Blauvelt A. (2009)
    57. CC-Chemokine ligand 20/macrophage inflammatory protein-3alpha and CC-chemokine receptor 6 are overexpressed in myeloma microenvironment related to osteolytic bone lesions. (PubMed id 18703490)1, 9 Giuliani N....Rizzoli V. (2008)
    58. Chemokine redundancy in BOS pathogenesis. A possible role also for the CC chemokines: MIP3-beta, MIP3-alpha, MDC and their specific receptors. (PubMed id 18047937)1, 9 Meloni F....Fietta A.M. (2008)
    59. Expression of macrophage inflammatory protein 3alpha in human inflamed dental pulp tissue. (PubMed id 15671814)1, 9 Nakanishi T....Matsuo T. (2005)
    60. Expression of the C-C chemokine MIP-3 alpha/CCL20 in human epidermis with impaired permeability barrier function. (PubMed id 11994140)1, 9 Schmuth M....Heufler C. (2002)
    61. Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. (PubMed id 10521347)1, 9 Yang D....Oppenheim J.J. (1999)
    62. ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6. (PubMed id 23011799)1 Miller M....Broide D.H. (2012)
    63. The role of chemokine CC ligand 20 in patients with li ver cirrhosis and hepatocellular carcinoma. (PubMed id 22388957)1 Soliman H.H....Alm El-Din M.A. (2012)
    64. MIP-3a expression in macrophages is NOD dependent. (PubMed id 22286692)1 Hausmann M....Rogler G. (2012)
    65. miR-21 functionally interacts with the 3'UTR of chemok ine CCL20 and down-regulates CCL20 expression in miR-21 transfected colorectal c ancer cells. (PubMed id 22099878)1 Vicinus B....Schilling M.K. (2012)
    66. Human keratinocytes' response to injury upregulates C CL20 and other genes linking innate and adaptive immunity. (PubMed id 21881590)1 Kennedy-Crispin M....Krueger J.G. (2012)
    67. Human papillomavirus type 8 interferes with a novel C/ EBPb-mediated mechanism of keratinocyte CCL20 chemokine expression and Langerhan s cell migration. (PubMed id 22911498)1 Sperling T....Smola S. (2012)
    68. MiR-21 is involved in cervical squamous cell tumorigen esis and regulates CCL20. (PubMed id 22001440)1 Yao T. and Lin Z. (2012)
    69. CCL5 and CCL20 mediate immigration of Langerhans cells into the epidermis of full thickness human skin equivalents. (PubMed id 22857950)1 Ouwehand K....Gibbs S. (2012)
    70. PI16 is expressed by a subset of human memory Treg wit h enhanced migration to CCL17 and CCL20. (PubMed id 22533972)1 Nicholson I.C....Krumbiegel D. (2012)
    71. Brucella invasion of human intestinal epithelial cells elicits a weak proinflammatory response but a significant CCL20 secretion. (PubMed id 22553918)1 Ferrero M.C....Baldi P.C. (2012)
    72. Interleukin (IL)-17A synergistically enhances CC chemo kine ligand 20 production in IL-1b-stimulated human gingival fibroblasts. (PubMed id 22019504)1 Hosokawa Y....Matsuo T. (2012)
    73. Epigenetic regulation of human I^-defensin 2 and CC ch emokine ligand 20 expression in gingival epithelial cells in response to oral b acteria. (PubMed id 21248725)1 Yin L. and Chung W.O. (2011)
    74. IL-22, but not IL-17, dominant environment in cutaneou s T-cell lymphoma. (PubMed id 22048239)1 Miyagaki T....Sato S. (2011)
    75. CCL20 and I^-defensin-2 induce arrest of human Th17 ce lls on inflamed endothelium in vitro under flow conditions. (PubMed id 21178014)1 Ghannam S....PA"ne J. (2011)
    76. Fusobacterium nucleatum and human beta-defensins modu late the release of antimicrobial chemokine CCL20/macrophage inflammatory prote in 3I+. (PubMed id 21911466)1 Ghosh S.K....Weinberg A. (2011)
    77. Chemokine (C-C) motif ligand 20 is regulated by PGF(2 I+)-F-prostanoid receptor signalling in endometrial adenocarcinoma and promotes cell proliferation. (PubMed id 20816914)1 Wallace A.E....Jabbour H.N. (2011)
    78. Effect of preoperative FOLFOX chemotherapy on CCL20/C CR6 expression in colorectal liver metastases. (PubMed id 21912453)1 Rubie C....Schilling M.K. (2011)
    79. CCL20 stimulates proinflammatory mediator synthesis in human fibroblast-like synoviocytes through a MAP kinase-dependent process with transcriptional and posttranscriptional control. (PubMed id 21724701)1 Alaaeddine N....Di Battista J.A. (2011)
    80. Control of cell migration and inflammatory mediators p roduction by CORM-2 in osteoarthritic synoviocytes. (PubMed id 21961038)1 Garcia-Arnandis I....Alcaraz M.J. (2011)
    81. Selective recruitment of regulatory T cell through CCR 6-CCL20 in hepatocellular carcinoma fosters tumor progression and predicts poor prognosis. (PubMed id 21935436)1 Chen K.J....Zheng S.S. (2011)
    82. CCL20/CCR6 feedback exaggerates epidermal growth fact or receptor-dependent MUC5AC mucin production in human airway epithelial (NCI-H 292) cells. (PubMed id 21300824)1 Kim S....Nadel J.A. (2011)
    83. Involvement of CCR6/CCL20/IL-17 axis in NSCLC disease progression. (PubMed id 21949768)1 Kirshberg S....Wald O. (2011)
    84. Exogenous HIV-1 Nef upsets the IFN-g-induced impairmen t of human intestinal epithelial integrity. (PubMed id 21858117)1 Quaranta M.G....Viora M. (2011)
    85. Risk of meningioma and common variation in genes rela ted to innate immunity. (PubMed id 20406964)1 Rajaraman P....Inskip P.D. (2010)
    86. Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)1 Han S....Kang D. (2010)
    87. Chemokine-mediated distribution of dendritic cell sub sets in renal cell carcinoma. (PubMed id 20969772)1 Middel P....Radzun H.J. (2010)
    88. CCL3 and CCL20-recruited dendritic cells modified by melanoma antigen gene-1 induce anti-tumor immunity against gastric cancer ex vi vo and in vivo. (PubMed id 20420712)1 He S....Zhang Y. (2010)
    89. Response of corneal epithelial cells to Staphylococcu s aureus. (PubMed id 21178448)1 Heimer S.R....Gilmore M. (2010)
    90. CCR6 ligands inhibit HIV by inducing APOBEC3G. (PubMed id 20023216)1 Lafferty M.K....Garzino-Demo A. (2010)
    91. Oxidative stress enhances IL-8 and inhibits CCL20 pro duction from intestinal epithelial cells in response to bacterial flagellin. (PubMed id 20595617)1 Ivison S.M....Steiner T.S. (2010)
    92. Expression of chemokine receptor CCR6 as a molecular determinant of adrenal metastatic relapse in patients with primary lung cancer. (PubMed id 20439195)1 Raynaud C.M....Soria J.C. (2010)
    93. Mesenchymal stem cells inhibit human Th17 cell differ entiation and function and induce a T regulatory cell phenotype. (PubMed id 20511548)1 Ghannam S....Yssel H. (2010)
    94. Chemokine control of HIV-1 infection: beyond a binding competition. (PubMed id 20942936)1 Wu Y. (2010)
    95. OX40 induces CCL20 expression in the context of antig en stimulation: an expanding role of co-stimulatory molecules in chemotaxis. (PubMed id 20400327)1 Zhong W....Rosenbaum J.T. (2010)
    96. Higher levels of CCL20 expression on peripheral blood mononuclear cells of chinese patients with inflammatory bowel disease. (PubMed id 20064082)1 He C....Li Y.Z. (2010)
    97. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
    98. CCL20 is overexpressed in Mycobacterium tuberculosis- infected monocytes and inhibits the production of reactive oxygen species (ROS) . (PubMed id 20819093)1 Rivero-Lezcano O.M....Diez-TascA^n C. (2010)
    99. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
    100. Upregulation of chemokine (C-C motif) ligand 20 in ad ult epidermal keratinocytes in direct current electric fields. (PubMed id 19784662)1 Jennings J.A....Feldman D.S. (2010)
    101. Toll-like receptor 5- and lymphotoxin beta receptor-d ependent epithelial Ccl20 expression involves the same NF-kappaB binding site b ut distinct NF-kappaB pathways and dynamics. (PubMed id 19303953)1 Sirard J.C....Rumbo M. (2009)
    102. Common variation in genes related to innate immunity and risk of adult glioma. (PubMed id 19423540)1 Rajaraman P....Chanock S.J. (2009)
    103. C-C chemokine receptor 6-regulated entry of TH-17 cel ls into the CNS through the choroid plexus is required for the initiation of EA E. (PubMed id 19305396)1 Reboldi A....Sallusto F. (2009)
    104. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    105. CARMA3 mediates lysophosphatidic acid-stimulated cytokine secretion by bronchial epithelial cells. (PubMed id 18757306)1 Medoff B.D....Xavier R.J. (2009)
    106. Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulator s. (PubMed id 19644053)1 Duffaut C....BouloumiAc A. (2009)
    107. Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. (PubMed id 18240029)1 Luttrell L.M. (2008)
    108. Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3alpha. (PubMed id 18684866)1 Lamprecht B....Mathas S. (2008)
    109. Exodus-1 (CCL20): evidence for the participation of this chemokine in spontaneous labor at term, preterm labor, and intrauterine infection. (PubMed id 18576931)1 Hamill N....Hassan S.S. (2008)
    110. Dissociation of heterotrimeric g proteins in cells. (PubMed id 18577758)1 Lambert N.A. (2008)
    111. Effects of MIP-1 alpha, MIP-3 alpha, and MIP-3 beta on the induction of HIV Gag-specific immune response with DNA vaccines. (PubMed id 17356539)1 Song R....Leong K.W. (2007)
    112. Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness. (PubMed id 17903302)1 Levy D....Mitchell G.F. (2007)
    113. High glucose induces macrophage inflammatory protein-3 alpha in renal proximal tubule cells via a transforming growth factor-beta 1 dependent mechanism. (PubMed id 17664181)1 Qi W....Pollock C.A. (2007)
    114. [Expression of CCL20 and CXCR4 in epidermal condyloma acuminatum lesions] (PubMed id 17545018)1 Feng J.Y....Liu Y.P. (2007)
    115. Structure of human MIP-3alpha chemokine. (PubMed id 16820679)1 Malik Z.A. and Tack B.F. (2006)
    116. MIP-3alpha/CCL20 in renal transplantation and its possible involvement as dendritic cell chemoattractant in allograft rejection. (PubMed id 16095490)1 Woltman A.M....van Kooten C. (2005)
    117. Primary human alveolar type II epithelial cell CCL20 (macrophage inflammatory protein-3alpha)-induced dendritic cell migration. (PubMed id 15618437)1 Thorley A.J....Tetley T.D. (2005)
    118. Chemokine CCL20 enhances the growth of HuH7 cells via phosphorylation of p44/42 MAPK in vitro. (PubMed id 15336571)1 Fujii H....Okanoue T. (2004)
    119. Astrocytes are the major intracerebral source of macrophage inflammatory protein-3alpha/CCL20 in relapsing experimental autoimmune encephalomyelitis and in vitro. (PubMed id 12528183)1 Ambrosini E....Aloisi F. (2003)
    120. Airway epithelial cells release MIP-3alpha/CCL20 in response to cytokines and ambient particulate matter. (PubMed id 12760962)1 Reibman J....Gordon T. (2003)
    121. Human B cells become highly responsive to macrophage-inflammatory protein-3 alpha/CC chemokine ligand-20 after cellular activation without changes in CCR6 expression or ligand binding. (PubMed id 11994436)1 Liao F....Farber J.M. (2002)
    122. HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication. (PubMed id 12089333)1 Cicala C....Fauci A.S. (2002)
    123. Influence of the mucosal epithelium microenvironment on Langerhans cells: implications for the development of squamous intraepitheli al lesions of the cervix. (PubMed id 11807793)1 Giannini S.L....Delvenne P. (2002)
    124. Macrophage inflammatory protein 3alpha-CC chemokine receptor 6 interactions play an important role in CD4+ T-cell accumulation in periodontal diseased tissue. (PubMed id 12067311)1 Hosokawa Y....Matsuo T. (2002)
    125. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    126. Versican interacts with chemokines and modulates cellular responses. (PubMed id 11083865)1 Hirose J....Miyasaka M. (2001)
    127. The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression. (PubMed id 8076819)1 Matoba R....Matsubara K. (1994)
    128. Co-localization of macrophage inflammatory protein-3alpha (Mip-3alpha) and its receptor, CCR6, promotes pancreatic cancer cell invasion. (PubMed id 15701269)9 Kimsey T.F....Wang T.N. (2004)
    129. Helicobacter pylori induces CCL20 expression. (PubMed id 17724069)9 Tomimori K....Mori N. (2007)
    130. Increase of CCL20 expression by human gingival fibroblasts upon stimulation with cytokines and bacterial endotoxin. (PubMed id 16232215)9 Hosokawa Y....Matsuo T. (2005)
    131. CCL20 is an inducible product of human airway epithelia with innate immune properties. (PubMed id 12748059)9 Starner T.D....McCray P.B. (2003)
    132. Macrophage inflammatory protein 3alpha deficiency in atopic dermatitis skin and role in innate immune response to vaccinia virus. (PubMed id 17141855)9 Kim B.E....Howell M.D. (2007)
    133. Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease. (PubMed id 17332482)9 Demedts I.K....Brusselle G.G. (2007)
    134. CCL20 produced in the cytokine network of rheumatoid arthritis recruits CCR6+ mononuclear cells and enhances the production of IL-6. (PubMed id 19535263)9 Tanida S....Nakamura T. (2009)
    135. Modulation of pathogen-induced CCL20 secretion from H T-29 human intestinal epithelial cells by commensal bacteria. (PubMed id 19814810)9 Sibartie S....Shanahan F. (2009)
    136. CCL20 production is induced in human dental pulp upon stimulation by Streptococcus mutans and proinflammatory cytokines. (PubMed id 18582332)9 Takahashi K....Matsuo T. (2008)
    137. Extravasation into synovial tissue induces CCL20 mRNA expression in polymorphonuclear neutrophils of patients with rheumatoid arthritis. (PubMed id 16331752)9 Schlenk J....Beuscher H.U. (2005)
    138. Corneal epithelial cells and stromal keratocytes efficently produce CC chemokine-ligand 20 (CCL20) and attract cells expressing its receptor CCR6 in mouse herpetic stromal keratitis. (PubMed id 15287366)9 Shirane J....Yoshie O. (2004)
    139. Lymphotoxin beta receptor signaling induces the chemokine CCL20 in intestinal epithelium. (PubMed id 15236187)9 Rumbo M....Finke D. (2004)
    140. Role of macrophage inflammatory protein-3alpha and its ligand CCR6 in rheumatoid arthritis. (PubMed id 12695561)9 Ruth J.H....Koch A.E. (2003)
    141. MCP-1 and MIP3-alpha serum levels in acute liver failure and molecular adsorbent recirculating system (MARS) treatment: a pilot study. (PubMed id 19247846)9 Roth G.A....Krenn C.G. (2009)
    142. Serum amyloid A protein stimulates CCL20 production i n rheumatoid synoviocytes. (PubMed id 19447772)9 Migita K....Ishibashi H. (2009)
    143. Substance P regulates macrophage inflammatory protein 3alpha/chemokine C-C ligand 20 (CCL20) with heme oxygenase-1 in human periodontal ligament cells. (PubMed id 17924972)9 Lee S.K....Kim E.C. (2007)
    144. Etanercept reduces the serum levels of interleukin-23 and macrophage inflammatory protein-3 alpha in patients with rheumatoid arthritis. (PubMed id 17619881)9 Kageyama Y....Nagano A. (2007)
    145. Increased expression of CCL20 in human inflammatory bowel disease. (PubMed id 14997037)9 Kaser A....Tilg H. (2004)
    146. Induction of macrophage-inflammatory protein-3alpha g ene expression by TNF-dependent NF-kappaB activation. (PubMed id 12023359)9 Sugita S....Matsuyama T. (2002)
    147. Iron chelator differentially activates macrophage inflammatory protein-3alpha/CCL20 in immortalized and malignant human oral keratinocytes. (PubMed id 18328460)9 Lee S.K....Kim E.C. (2008)
    148. Expression and regulation of the CC-chemokine ligand 20 during human tuberculosis. (PubMed id 18052967)9 Lee J.S....Jo E.K. (2008)
    149. Odontoblast marker gene expression is enhanced by a CC-chemokine family protein MIP-3alpha in human mesenchymal stem cells. (PubMed id 17532291)9 Iejima D....Ueda M. (2007)
    150. Up-regulation of chemokine ligand 20 in chronic rhinosinusitis. (PubMed id 16702571)9 Lee J.H....Lee H.M. (2006)
    151. Iron chelator induces MIP-alpha/CCL20 in human intestinal epithelial cells: implication for triggering mucosal adaptive immunity. (PubMed id 16155407)9 Lee H.J....Jun C.D. (2005)
    152. Increased expression of MIP-3alpha/CCL20 in peripheral blood mononuclear cells from patients with ulcerative colitis and its down-regulation by sulfasalazine and glucocorticoid treatment. (PubMed id 16306769)9 Lee H.J....Jun C.D. (2005)
    153. A combination of MIP-3alpha and TGF-beta1 is required for the attraction of human Langerhans precursor cells through a dermal-epidermal barrier. (PubMed id 11432723)9 Godefroy S....Staquet M.J. (2001)
    154. Detection and localization of Mip-3alpha/LARC/Exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer. (PubMed id 10225458)9 Kleeff J....Korc M. (1999)
    155. Macrophage-inflammatory protein-3alpha/CCL-20 is tran scriptionally induced by the iron chelator desferrioxamine in human mononuclear phagocytes through nuclear factor (NF)-kappaB. (PubMed id 19939449)9 Varesio L....Bosco M.C. (2010)
    156. Macrophage inflammatory protein-3alpha promotes pancreatic cancer cell invasion. (PubMed id 15652956)9 Campbell A.S....Wang T.N. (2005)
    157. Interleukin-17 increases the effects of IL-1 beta on muscle cells: arguments for the role of T cells in the pathogenesis of myositis. (PubMed id 12667656)9 Chevrel G....Miossec P. (2003)
    158. Effects of leptin on the production of cytokines by cultured human endometrial stromal and epithelial cells. (PubMed id 14505754)9 Fukuda J....Miyakawa I. (2003)
    159. Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: mechanism for modulating mucosal immunity. (PubMed id 11254498)9 Izadpanah A....Kagnoff M.F. (2001)
    160. Enhancing effect of IL-1, IL-17, and TNF-alpha on macrophage inflammatory protein-3alpha production in rheumatoid arthritis: regulation by soluble receptors and Th2 cytokines. (PubMed id 11698482)9 Chabaud M....Miossec P. (2001)
    161. CC-chemokine receptor 6 is expressed on diverse memory subsets of T cells and determines responsiveness to macrophage inflammatory protein 3 alpha. (PubMed id 9886385)9 Liao F....Farber J.M. (1999)
    162. Increased migration of Langerhans cells in response to HPV16 E6 and E7 oncogene silencing: role of CCL20. (PubMed id 18438663)9 Caberg J.H....Delvenne P. (2009)
    163. Catechins inhibit CCL20 production in IL-17A-stimulat ed human gingival fibroblasts. (PubMed id 19910679)9 Hosokawa Y....Matsuo T. (2009)
    164. Function of liver activation-regulated chemokine/CC chemokine ligand 20 is differently affected by cathepsin B and cathepsin D processing. (PubMed id 16709808)9 Hasan L....Wolf M. (2006)
    165. The expression of interleukin-17, interferon-gamma, and macrophage inflammatory protein-3 alpha mRNA in patients with psoriasis vulgaris. (PubMed id 15315354)9 Li J....Tan Z. (2004)
    166. Macrophage inflammatory protein 3alpha is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors. (PubMed id 10974036)9 Dieu-Nosjean M.C....Caux C. (2000)
    167. A novel rat CC chemokine, identified by targeted differential display, is upregulated in brain inflammation. (PubMed id 9916893)9 Utans-Schneitz U....Lesslauer W. (1998)
    168. Chemokine receptor CCR6 expression level and aggressiveness of prostate cancer. (PubMed id 18465142)9 Ghadjar P....Keilholz U. (2008)
    169. The NF-kappaB, p38 MAPK and STAT1 pathways differentially regulate the dsRNA-mediated innate immune responses of epidermal keratinocytes. (PubMed id 18492658)9 Dai X....Hashimoto K. (2008)
    170. Ocular surface expression and in vitro activity of antimicrobial peptides. (PubMed id 17852183)9 Huang L.C....McDermott A.M. (2007)
    171. MIP-3alpha neutralizing monoclonal antibody protects against TNBS-induced colonic injury and inflammation in mice. (PubMed id 17272517)9 Katchar K....Keates A.C. (2007)
    172. Chemokine receptor CCR6 as a prognostic factor after hepatic resection for hepatocellular carcinoma. (PubMed id 16706828)9 Uchida H....Kitano S. (2006)
    173. Down-regulation of tristetraprolin expression results in enhanced IL-12 and MIP-2 production and reduced MIP-3alpha synthesis in activated macrophages. (PubMed id 17392586)9 Jalonen U....Moilanen E. (2006)
    174. DA-9601, a standardized extract of Artemisia asiatica, blocks TNF-alpha-induced IL-8 and CCL20 production by inhibiting p38 kinase and NF-kappaB pathways in human gastric epithelial cells. (PubMed id 16937467)9 Choi S.C....Jun C.D. (2006)
    175. Epigallocatechin-3-gallate impairs chemokine production in human colon epithelial cell lines. (PubMed id 16123309)9 Porath D....Schwager J. (2005)
    176. Differential induction of the toll-like receptor 4-MyD88-dependent and -independent signaling pathways by endotoxins. (PubMed id 15845500)9 Zughaier S.M....Stephens D.S. (2005)
    177. Characterization of CCL20 secretion by human epithelial vaginal cells: involvement in Langerhans cell precursor attraction. (PubMed id 15831560)9 Cremel M....Delezay O. (2005)
    178. MIP-3alpha transfection into a rodent tumor cell line increases intratumoral dendritic cell infiltration but enhances (facilitates) tumor growth and decreases immunogenicity. (PubMed id 15470034)9 Bonnotte B....Vile R.G. (2004)
    179. IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice. (PubMed id 12627325)9 Cardozo A.K....Eizirik D.L. (2003)
    180. CCL20/macrophage inflammatory protein-3alpha production in LPS-stimulated neutrophils is enhanced by the chemoattractant formyl-methionyl-leucyl-phenylalanine and IFN-gamma through independent mechanisms. (PubMed id 12442334)9 Scapini P....Cassatella M.A. (2002)
    181. Novel lymphocyte-specific CC chemokines and their receptors. (PubMed id 9365118)9 Yoshie O....Nomiyama H. (1997)
    182. Gene expression profiles of nasal polyps associated with allergic rhinitis. (PubMed id 19027509)9 Wu J....Jingping F. (2009)
    183. Chemokine expression in human erythroid leukemia cell line AS-E2: macrophage inflammatory protein-3alpha/CCL20 is induced by inflammatory cytokines. (PubMed id 16413387)9 Inoue Y....Tomonaga M. (2006)
    184. Modulation of toll-like receptor 7 and LL-37 expression in colon and breast epithelial cells by human beta-defensin-2. (PubMed id 16270724)9 Stroinigg N. and Srivastava M.D. (2005)
    185. Chemokine receptor CCR6 transduces signals that activate p130Cas and alter cAMP-stimulated ion transport in human intestinal epithelial cells. (PubMed id 15483227)9 Yang C.C....Kagnoff M.F. (2005)
    186. Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locus control region. (PubMed id 16217013)9 Mahajan M.C....Weissman S.M. (2005)
    187. Up-regulation of CC chemokine ligand 20 expression in human airway epithelium by IL-17 through a JAK-independent but MEK/NF-kappaB-dependent signaling pathway. (PubMed id 16272323)9 Kao C.Y....Wu R. (2005)
    188. Expression of CC chemokine ligand 20 and CC chemokine receptor 6 mRNA in patients with psoriasis vulgaris. (PubMed id 15315355)9 Wu Y. and Li J. (2004)
    189. Production of macrophage inflammatory protein 3alpha (MIP-3alpha) (CCL20) and MIP-3beta (CCL19) by human peripheral blood neutrophils in response to microbial pathogens. (PubMed id 12496204)9 Akahoshi T....Kondo H. (2003)
    190. CC chemokine ligand 20 partially controls adhesion of naive B cells to activated endothelial cells under shear stress. (PubMed id 12816871)9 Meissner A....Korner H. (2003)
    191. CC-chemokine receptor 6 and its ligand macrophage inflammatory protein 3alpha might be involved in the amplification of local necroinflammatory response in the liver. (PubMed id 11481616)9 Shimizu Y....Watanabe A. (2001)
    192. NMR solution structure of murine CCL20/MIP-3alpha, a chemokine that specifically chemoattracts immature dendritic cells and lymphocytes through its highly specific interaction with the beta-chemokine receptor CCR6. (PubMed id 11373289)9 Perez-Canadillas J.M....Bruix M. (2001)
    193. MIP-3alpha induces human eosinophil migration and activation of the mitogen-activated protein kinases (p42/p44 MAPK). (PubMed id 10534125)9 Sullivan S.K....Bacon K.B. (1999)
    194. The tight relationship between papillary thyroid canc er, autoimmunity and inflammation: clinical and molecular studies. (PubMed id 20447069)9 Muzza M....Fugazzola L. (2010)
    195. Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthrit is. (PubMed id 19804625)9 Nanki T....Miyasaka N. (2009)
    196. IL-17 and IL-22 mediate IL-20 subfamily cytokine prod uction in cultured keratinocytes via increased IL-22 receptor expression. (PubMed id 19731362)9 Tohyama M....Hashimoto K. (2009)
    197. Exuberant expression of chemokine genes by adult human articular chondrocytes in response to IL-1beta. (PubMed id 18565769)9 Sandell L.J....Patra D. (2008)
    198. Urinary fractalkine is a marker of acute rejection. (PubMed id 18800027)9 Peng W....Wang H. (2008)
    199. Differential regulation of chemokines by IL-17 in colonic epithelial cells. (PubMed id 18941244)9 Lee J.W....Straus D.S. (2008)
    200. IL-17RA and IL-17RC receptors are essential for IL-17A-induced ELR+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood. (PubMed id 18097068)9 Zrioual S....Miossec P. (2008)
    201. Macrophage inflammatory protein-3alpha influences growth of K562 leukemia cells in co-culture with anticancer drug-pretreated HS-5 stromal cells. (PubMed id 18538911)9 Lee Y.C....Chu S.T. (2008)
    202. Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis. (PubMed id 17615381)9 Facco M....Agostini C. (2007)
    203. Differential regulation of immune responses by odontoblasts. (PubMed id 17241164)9 Veerayutthwilai O....Dale B.A. (2007)
    204. Allergen-IgE complexes trigger CD23-dependent CCL20 release from human intestinal epithelial cells. (PubMed id 18054562)9 Li H....Berin M.C. (2007)
    205. Accumulation of immune cells and high expression of chemokines/chemokine receptors in the upstream shoulder of atherosclerotic carotid plaques. (PubMed id 17222820)9 Yilmaz A....Garlichs C.D. (2007)
    206. Monocyte chemoattractant protein-1 (MCP-1) inhibits the intestinal-like differentiation of monocytes. (PubMed id 16792690)9 Spoettl T....Rogler G. (2006)
    207. Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene. (PubMed id 16203990)9 Borrello M.G....Pierotti M.A. (2005)
    208. The chemokines CCL11, CCL20, CCL21, and CCL24 are preferentially expressed in polarized human secondary lymphoid follicles. (PubMed id 15376263)9 Buri C....Mueller C. (2004)
    209. Expression of macrophage inflammatory protein-3alpha, stromal cell-derived factor-1, and B-cell-attracting chemokine-1 identifies the tonsil crypt as an attractive site for B cells. (PubMed id 11389046)9 Casamayor-Palleja M....Defrance T. (2001)
    210. IL-10 induces CCR6 expression during Langerhans cell development while IL-4 and IFN-gamma suppress it. (PubMed id 11698430)9 Dieu-Nosjean M.C....Caux C. (2001)
    211. Influenza A and sendai viruses induce differential chemokine gene expression and transcription factor activation in human macrophages. (PubMed id 11022002)9 Matikainen S....Julkunen I. (2000)
    212. Macrophage inflammatory protein 3alpha transgene attr acts dendritic cells to established murine tumors and suppresses tumor growth. (PubMed id 10811846)9 Fushimi T....Crystal R.G. (2000)
    213. Cutting edge: C-C chemokine receptor 6 is essential for arrest of a subset of memory T cells on activated dermal microvascular endothelial cells under physiologic flow conditions in vitro. (PubMed id 11120783)9 Fitzhugh D.J....Hwang S.T. (2000)
    214. Expression and cellular localization of the CC chemokines PARC and ELC in human atherosclerotic plaques. (PubMed id 10027395)9 Reape T.J....Groot P.H. (1999)
    215. Opposing roles of IL-17A and IL-25 in the regulation of TSLP production in human nasal epithelial cells. (PubMed id 19968632)9 Xu G....Li H.B. (2010)
    216. Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cel ls are highly permissive to HIV-1 infection. (PubMed id 20042588)9 Gosselin A....Ancuta P. (2010)
    217. Interleukin-17 and its target genes: mechanisms of in terleukin-17 function in disease. (PubMed id 20409152)9 Onishi R.M. and Gaffen S.L. (2010)
    218. CCR6 is expressed on an IL-10-producing, autoreactive memory T cell population with context-dependent regulatory function. (PubMed id 20194631)9 Rivino L....Geginat J. (2010)
    219. Development of an in vitro dual-chamber model of the female genital tract as a screening tool for epithelial toxicity. (PubMed id 20138087)9 Gali Y....Vanham G. (2010)
    220. Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis. (PubMed id 19196728)9 Melis L....Elewaut D. (2010)
    221. Down-regulation of intestinal epithelial innate respo nse by probiotic yeasts isolated from kefir. (PubMed id 20471126)9 Romanin D....Rumbo M. (2010)
    222. [Th17 cells in the pathogenesis of multiple sclerosis ] (PubMed id 19940328)9 Juszczak M. and GA8abiA8ski A. (2009)
    223. The human antimicrobial peptide dermcidin activates normal human keratinocytes. (PubMed id 19014393)9 Niyonsaba F....Okumura K. (2009)
    224. Identification and functional characterization of a spliced rhesus rhadinovirus gene with homology to the K15 gene of Kaposi's sarcoma-associated herpesvirus. (PubMed id 19264656)9 Wang L....Schulz T.F. (2009)
    225. Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. (PubMed id 19273625)9 Boniface K....de Waal Malefyt R. (2009)
    226. Emerging role of tumour necrosis factor-related apopt osis-inducing ligand (TRAIL) as a key regulator of inflammatory responses. (PubMed id 19656161)9 Collison A....Mattes J. (2009)
    227. Secretory products from human adipocytes stimulate proinflammatory cytokine secretion from human endothelial cells. (PubMed id 19173302)9 Sommer G....Fasshauer M. (2009)
    228. Differential effects of cytokines and corticosteroids on toll-like receptor 2 expression and activity in human airway epithelia. (PubMed id 19835594)9 Winder A.A....McCray P.B. (2009)
    229. TRAIL receptor mediates inflammatory cytokine release in an NF-kappaB-dependent manner. (PubMed id 19434100)9 Tang W....Zheng D. (2009)
    230. Innate immune responses of airway epithelium to house dust mite are mediated through beta-glucan-dependent pathways. (PubMed id 19178937)9 Nathan A.T....Wills-Karp M. (2009)
    231. Liver transcriptome profiles associated with strain-specific Ehrlichia chaffeensis-induced hepatitis in SCID mice. (PubMed id 19001077)9 Miura K. and Rikihisa Y. (2009)
    232. Differential innate immune responses of a living skin equivalent model colonized by Staphylococcus epidermidis or Staphylococcus aureus. (PubMed id 19054079)9 Holland D.B....Holland K.T. (2009)
    233. Interaction analyses of human monocytes co-cultured with different forms of Aspergillus fumigatus. (PubMed id 19074652)9 Loeffler J....Hebart H. (2009)
    234. Plasmodium falciparum-infected erythrocytes induce NF -kappaB regulated inflammatory pathways in human cerebral endothelium. (PubMed id 19713460)9 Tripathi A.K....Sullivan D.J. (2009)
    235. [Regulation of immune suppressive cytokines by TLR4 a ctivation in colon cancer cells] (PubMed id 19598032)9 Qi H.M....Wang J. (2009)
    236. Up-regulation of CC chemokine receptor 6 on tonsillar T cells and its induction by in vitro stimulation with alpha-streptococci in p atients with pustulosis palmaris et plantaris. (PubMed id 19659772)9 Yoshizaki T....Harabuchi Y. (2009)
    237. Lactobacillus rhamnosus GG and Lactobacillus casei suppress Escherichia coli-induced chemokine expression in intestinal epithelial cells. (PubMed id 18716403)9 Toki S....Matsumoto K. (2009)
    238. CXC and CC chemokines induced in human renal epitheli al cells by inflammatory cytokines. (PubMed id 19594487)9 Thorburn E....Striz I. (2009)
    239. Conditioning vaccination site with irradiated MIP-3alpha-transfected tumor cells enhances efficacy of dendritic cell-based cancer vaccine. (PubMed id 19342969)9 Shih N.Y....Liu K.J. (2009)
    240. A novel Toll-like receptor 4 antagonist antibody amel iorates inflammation but impairs mucosal healing in murine colitis. (PubMed id 19359427)9 Ungaro R....Abreu M.T. (2009)
    241. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced chemokine release in both TRAIL-resistant and TRAIL-sensitive cells via nuclear factor kappa B. (PubMed id 19120450)9 Tang W....Zheng D. (2009)
    242. Interleukin-1 regulates keratinocyte expression of T cell targeting chemokines through interleukin-1 receptor associated kinase-1 (IRAK1) dependent and independent pathways. (PubMed id 19166933)9 Sanmiguel J.C....Jensen L.E. (2009)
    243. Development and function of TH17 cells in health and disease. (PubMed id 19410689)9 Louten J....de Waal Malefyt R. (2009)
    244. Activation of the extrinsic apoptotic pathway by TNF- alpha in human salivary gland (HSG) cells in vitro, suggests a role for the TNF receptor (TNF-R) and intercellular adhesion molecule-1 (ICAM-1) in SjAPgren's s yndrome-associated autoimmune sialadenitis. (PubMed id 19716548)9 Wang Y....McArthur C. (2009)
    245. Cytokine and chemokine expression patterns in lung epithelial cells exposed to components characteristic of particulate air pollution. (PubMed id 19428942)9 Ovrevik J....Refsnes M. (2009)
    246. The anti-inflammatory effect of low-dose radiation therapy involves a diminished CCL20 chemokine expression and granulocyte/endothelial cell adhesion. (PubMed id 18188522)9 Rodel F....Beuscher H.U. (2008)
    247. Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study. (PubMed id 18205922)9 Andreas K....Sittinger M. (2008)
    248. Microarray analysis of amphotericin B-treated THP-1 monocytic cells identifies unique gene expression profiles among lipid and non-lipid drug formulations. (PubMed id 18606588)9 Turtinen L.W....Obr A. (2008)
    249. Ex vivo simulation of IgG Fc and T-cell receptor functions: an application to inflammatory bowel disease. (PubMed id 18340639)9 Mitsuhashi M. and Targan S.R. (2008)
    250. Activation of an immunoregulatory and antiviral gene expression program in poly(I:C)-transfected human neutrophils. (PubMed id 18941247)9 Tamassia N....Cassatella M.A. (2008)
    251. CCR6 regulates the migration of inflammatory and regulatory T cells. (PubMed id 19050256)9 Yamazaki T....Dong C. (2008)
    252. Decreased expression of intestinal chemokine TECK/CCL25 in experimental obstructive jaundice and its reversal following internal biliary drainage. (PubMed id 18592157)9 Matsumoto T....Ku Y. (2008)
    253. Identification of cellular pathways of 'type 1,' Th17 T cells, and TNF- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis. (PubMed id 18209089)9 Haider A.S....Krueger J.G. (2008)
    254. Characterization and partial purification of Candida albicans Secretory IL-12 Inhibitory Factor. (PubMed id 18282300)9 Wang M....Ghannoum M.A. (2008)
    255. Interleukin (IL)-1 promotes allogeneic T cell intimal infiltration and IL-17 production in a model of human artery rejection. (PubMed id 19075290)9 Rao D.A....Pober J.S. (2008)
    256. Capture of an activated receptor complex from the surface of live cells by affinity receptor chromatography. (PubMed id 18601892)9 Jankowski A....Marshall J.G. (2008)
    257. Human dendritic cells differentiated in hypoxia down-modulate antigen uptake and change their chemokine expression profile. (PubMed id 18725395)9 Elia A.R....Giovarelli M. (2008)
    258. Comparison of expression profiles induced by dust mite in airway epithelia reveals a common pathway. (PubMed id 18315734)9 Vroling A.B....van Drunen C.M. (2008)
    259. Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion. (PubMed id 18698005)9 Chizzolini C....Dayer J.M. (2008)
    260. Decreased cytokine and chemokine mRNA expression in bronchoalveolar lavage in asymptomatic smoking subjects. (PubMed id 18230951)9 Meuronen A....Laitinen A. (2008)
    261. Leukocyte adhesion molecule and chemokine production through lipoteichoic acid recognition by toll-like receptor 2 in cultured human lymphatic endothelium. (PubMed id 18523807)9 Sawa Y....Yoshida S. (2008)
    262. Expression analysis of CCL27 and CCL28 mRNA in lesional and non-lesional skin of dogs with atopic dermatitis. (PubMed id 18250572)9 Maeda S....Kitagawa H. (2008)
    263. A pilot study to explore the usefulness of antibody array in childhood atopic dermatitis. (PubMed id 18507202)9 Hon K.L....Leung A.K. (2008)
    264. Modulation of chemokine gene expression by Shiga-toxin producing Escherichia coli belonging to various origins and serotypes. (PubMed id 18248761)9 Gobert A.P....Martin C. (2008)
    265. Augmentation of UVB radiation-mediated early gene expression by the epidermal platelet-activating factor receptor. (PubMed id 17928889)9 Travers J.B....Konger R.L. (2008)
    266. Tyrosine phosphatase SHP-1 in oxidative stress and development of allergic airway inflammation. (PubMed id 18441283)9 Cho Y.S....Zhu Z. (2008)
    267. S100A8/A9, a key mediator for positive feedback growth stimulation of normal human keratinocytes. (PubMed id 18044712)9 Nukui T....Huh N.H. (2008)
    268. Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells. (PubMed id 18364398)9 Spadaro M....Giovarelli M. (2008)
    269. [Gene expression profiles in human nasal polyps studied by DNA microarray] (PubMed id 18727517)9 Liu B....Peng Y. (2008)
    270. Anthrax lethal toxin suppresses chemokine production in human neutrophil NB-4 cells. (PubMed id 18625197)9 Barson H.V....Rijpkema S. (2008)
    271. Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates Up-regulation of CCL20 and the migration of regulatory T cells. (PubMed id 18502823)9 Baumforth K.R....Murray P.G. (2008)
    272. Leptin induces an Apc genotype-associated colon epithelial cell chemokine production pattern associated with macrophage chemotaxis and activation. (PubMed id 16891627)9 Fenton J.I....Hord N.G. (2007)
    273. Dissecting genetic predisposition to inflammatory bow el disease: current progress and prospective application. (PubMed id 20477673)9 Annese V....Andriulli A. (2007)
    274. Shiga toxin produced by enterohemorrhagic Escherichia coli inhibits PI3K/NF-kappaB signaling pathway in globotriaosylceramide-3-negative human intestinal epithelial cells. (PubMed id 17548655)9 Gobert A.P....Martin C. (2007)
    275. Keratinocyte chemoattractant (KC)/human growth-regulated oncogene (GRO) chemokines and pro-inflammatory chemokine networks in mouse and human ovarian epithelial cancer cells. (PubMed id 17712227)9 Son D.S....Khabele D. (2007)
    276. Protease-activated receptor 2 mediates human beta-defensin 2 and CC chemokine ligand 20 mRNA expression in response to proteases secreted by Porphyromonas gingivalis. (PubMed id 17591792)9 Dommisch H....Dale B.A. (2007)
    277. Dendritic cells accumulate in human fibrotic interstitial lung disease. (PubMed id 17717200)9 Marchal-SommAc J....Soler P. (2007)
    278. Modulation of chemokines by staphylococcal superantigen in atopic dermatitis. (PubMed id 17369706)9 Homey B....Lauerma A. (2007)
    279. Hev b 6.01 and Hev b 5 induce pro-inflammatory cytokines and chemokines from peripheral blood mononuclear cells in latex allergy. (PubMed id 17210051)9 Lehto M....Alenius H. (2007)
    280. Mucosal safety of PHI-443 and stampidine as a combination microbicide to prevent genital transmission of HIV-1. (PubMed id 17498709)9 D'Cruz O.J. and Uckun F.M. (2007)
    281. CC-chemokine receptors in chronic obstructive pulmonary disease. (PubMed id 17692030)9 Bracke K.R....Brusselle G.G. (2007)
    282. Correlation of dendritic cell infiltration with active crypt inflammation in ulcerative colitis. (PubMed id 17178254)9 Watanabe S....Kimura O. (2007)
    283. Human keratinocytes express functional Toll-like receptor 3, 4, 5, and 9. (PubMed id 17068485)9 Lebre M.C....de Jong E.C. (2007)
    284. Dual effect of butyrate on IL-1beta--mediated intestinal epithelial cell inflammatory response. (PubMed id 17417942)9 Blais M....Asselin C. (2007)
    285. Malignant B cells from patients with primary central nervous system lymphoma express stromal cell-derived factor-1. (PubMed id 17369141)9 Smith J.R....Braziel R.M. (2007)
    286. Caspase-4 interacts with TNF receptor-associated factor 6 and mediates lipopolysaccharide-induced NF-kappaB-dependent production of IL-8 and CC chemokine ligand 4 (macrophage-inflammatory protein-1 ). (PubMed id 18056395)9 Lakshmanan U. and Porter A.G. (2007)
    287. Requirement for both JAK-mediated PI3K signaling and ACT1/TRAF6/TAK1-dependent NF-kappaB activation by IL-17A in enhancing cytokine expression in human airway epithelial cells. (PubMed id 17982039)9 Huang F....Wu R. (2007)
    288. Functional genomics of innate host defense molecules in normal human monocytes in response to Aspergillus fumigatus. (PubMed id 16552065)9 Cortez K.J....Walsh T.J. (2006)
    289. Characterization of the divergent wound-healing responses occurring in the pathergy reaction and normal healthy volunteers. (PubMed id 17056573)9 Melikoglu M....Oliver S. (2006)
    290. Increased number of mature dendritic cells in Crohn's disease: evidence for a chemokine mediated retention mechanism. (PubMed id 16118351)9 Middel P....Radzun H.J. (2006)
    291. The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors. (PubMed id 16982885)9 Hirahara K....Kupper T.S. (2006)
    292. Control of cytokine gene expression by PG101, a water-soluble extract prepared from Lentinus lepideus. (PubMed id 16344041)9 Choi J.J....Kim S. (2006)
    293. Tumor necrosis factor-alpha- and IL-4-independent development of Langerhans cell-like dendritic cells from M-CSF-conditioned precursors. (PubMed id 16417226)9 Barbaroux J.B....Mueller C.G. (2006)
    294. Involvement of chemokine receptor CCR6 in colorectal cancer metastasis. (PubMed id 16641550)9 Rubie C....Schilling M. (2006)
    295. Polysaccharide purified from Ganoderma lucidum induces gene expression changes in human dendritic cells and promotes T helper 1 immune response in BALB/c mice. (PubMed id 16670374)9 Lin Y.L....Chiang B.L. (2006)
    296. Detection of up-regulated genes in thrombin-stimulated human umbilical vein endothelial cells. (PubMed id 16356540)9 Okada M....Shinohara T. (2006)
    297. Identification of proteins differentially expressed in human monocytes exposed to Porphyromonas gingivalis and its purified components by high-throughput immunoblotting. (PubMed id 16428770)9 Zhou Q. and Amar S. (2006)
    298. Mesothelioma environment comprises cytokines and T-regulatory cells that suppress immune responses. (PubMed id 16540497)9 Hegmans J.P....Lambrecht B.N. (2006)
    299. Biocompatibility of solid-dosage forms of anti-human immunodeficiency virus type 1 microbicides with the human cervicovaginal mucosa modeled ex vivo. (PubMed id 17030562)9 Trifonova R.T....Fichorova R.N. (2006)
    300. The multifaceted roles of chemokines in malignancy. (PubMed id 17016763)9 Ben-Baruch A. (2006)
    301. Identification of specific gene expression profiles in fibroblasts derived from middle ear cholesteatoma. (PubMed id 16847181)9 Yoshikawa M....Moriyama H. (2006)
    302. Synthetic double-stranded RNA induces multiple genes related to inflammation through Toll-like receptor 3 depending on NF-kappaB and/or IRF-3 in airway epithelial cells. (PubMed id 16911361)9 Matsukura S....Adachi M. (2006)
    303. Gene-inducing program of human dendritic cells in response to BCG cell-wall skeleton (CWS), which reflects adjuvancy required for tumor immunotherapy. (PubMed id 15860229)9 Ishii K....Seya T. (2005)
    304. Astrocytes produce dendritic cell-attracting chemokines in vitro and in multiple sclerosis lesions. (PubMed id 16106219)9 Ambrosini E....Coccia E.M. (2005)
    305. Three-dimensional culture of melanoma cells profoundly affects gene expression profile: a high density oligonucleotide array study. (PubMed id 15744745)9 Ghosh S....Reschner A. (2005)
    306. TNF inhibition rapidly down-regulates multiple proinflammatory pathways in psoriasis plaques. (PubMed id 16081850)9 Gottlieb A.B....Krueger J.G. (2005)
    307. CXCL12 and CXCR4 expression by human gingival fibroblasts in periodontal disease. (PubMed id 16045736)9 Hosokawa Y....Matsuo T. (2005)
    308. Patterns of protein expression in infectious meningitis: a cerebrospinal fluid protein array analysis. (PubMed id 15885808)9 Kastenbauer S....Koedel U. (2005)
    309. Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory response. (PubMed id 16316467)9 Ritter M....Seither P. (2005)
    310. Novel markers of the human follicle-associated epithelium identified by genomic profiling and microdissection. (PubMed id 16012957)9 Anderle P....Kraehenbuhl J.P. (2005)
    311. Cytokine interactions in mesenchymal stem cells from cord blood. (PubMed id 16377203)9 Liu C.H. and Hwang S.M. (2005)
    312. An optimized method for intensive screening of molecules that stimulate beta-defensin 2 or 3 (hBD2 or hBD3) expression in cultured normal human keratinocytes. (PubMed id 18492183)9 Pernet I....Perrier E. (2005)
    313. The inflammatory side of human chondrocytes unveiled by antibody microarrays. (PubMed id 15381094)9 De Ceuninck F....Anract P. (2004)
    314. Human beta-defensin-2 functions as a chemotactic agent for tumour necrosis factor-alpha-treated human neutrophils. (PubMed id 15009427)9 Niyonsaba F....Nagaoka I. (2004)
    315. Description of B lymphocytes and plasma cells, complement, and chemokines/receptors in acute liver allograft rejection. (PubMed id 15257040)9 Krukemeyer M.G....Krenn V. (2004)
    316. Treatment of cerebellar granule cell neurons with the neurotrophic factor pigment epithelium-derived factor in vitro enhances expression of other neurotrophic factors as well as cytokines and chemokines. (PubMed id 15352210)9 Yabe T....Schwartz J.P. (2004)
    317. The characterization of chemokine production and chemokine receptor expression reveals possible functional cross-talks in AML blasts with monocytic differentiation. (PubMed id 12829025)9 Cignetti A....Ghia P. (2003)
    318. Exacerbated and prolonged allergic and non-allergic inflammatory cutaneous reaction in mice with targeted interleukin-18 expression in the skin. (PubMed id 12925208)9 Kawase Y....Yoshino K. (2003)
    319. Coincident expression of the chemokine receptors CCR6 and CCR7 by pathologic Langerhans cells in Langerhans cell histiocytosis. (PubMed id 12642342)9 Fleming M.D....Rollins B.J. (2003)
    320. The CC chemokine CCL20 and its receptor CCR6. (PubMed id 12948524)9 Schutyser E....Van Damme J. (2003)
    321. Lactobacilli and streptococci induce inflammatory chemokine production in human macrophages that stimulates Th1 cell chemotaxis. (PubMed id 12949243)9 Veckman V....Julkunen I. (2003)
    322. LPS and Freund's adjuvant initiate different inflammatory circuits in experimental autoimmune thyroiditis. (PubMed id 12799214)9 Damotte D....Carnaud C. (2003)
    323. IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling. (PubMed id 11884467)9 Zhu Z....Elias J.A. (2002)
    324. CCR6 is a functional chemokine receptor that serves to identify select B-cell non-Hodgkin's lymphomas. (PubMed id 12514792)9 Rodig S.J....Dorfman D.M. (2002)
    325. Chemotaxis of human tonsil B lymphocytes to CC chemokine receptor (CCR) 1, CCR2 and CCR4 ligands is restricted to non-germinal center cells. (PubMed id 12147625)9 Corcione A....Pistoia V. (2002)
    326. Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in type 1 diabetes mellitus. (PubMed id 11897677)9 Liu D....Eizirik D.L. (2002)
    327. Gene expression profiles for Fc epsilon RI, cytokines and chemokines upon Fc epsilon RI activation in human cultured mast cells derived from peripheral blood. (PubMed id 11792124)9 Wakahara S....Ra C. (2001)
    328. Changes in gene expression in macrophages infected with Mycobacterium tuberculosis: a combined transcriptomic and proteomic approach. (PubMed id 11576227)9 Ragno S....Colston M.J. (2001)
    329. Identification, mapping, and phylogenetic analysis of three novel chicken CC chemokines. (PubMed id 11797102)9 Hughes S....Bumstead N. (2001)
    330. Angioimmunoblastic lymphadenopathy-type peripheral T-cell lymphoma with cutaneous infiltration: report of a case and its gene expression profile. (PubMed id 11298554)9 Murakami T....Nakagawa H. (2001)
    331. Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells. (PubMed id 11717433)9 Sierro F....Sirard J.C. (2001)
    332. Chemokine receptor expressions and responsiveness of cord blood T cells. (PubMed id 11160208)9 Sato K....Takahashi T. (2001)
    333. Selective attraction of naive and memory B cells by dendritic cells. (PubMed id 11590201)9 Dubois B....Caux C. (2001)
    334. TGF-beta 1 reciprocally controls chemotaxis of human peripheral blood monocyte-derived dendritic cells via chemokine receptors. (PubMed id 10679062)9 Sato K....Takahashi T.A. (2000)
    335. Molecular analysis of the hematopoiesis supporting osteoblastic cell line U2-OS. (PubMed id 10781900)9 Nelissen J.M....Figdor C.G. (2000)
    336. Comprehensive gene expression profile of LPS-stimulated human monocytes by SAGE. (PubMed id 11001915)9 Suzuki T....Matsushima K. (2000)
    337. Expression of CCR6 and CD83 by cytokine-activated human neutrophils. (PubMed id 11090084)9 Yamashiro S....Yoshimura T. (2000)
    338. Papillary carcinoma of the thyroid: hepatocyte growth factor (HGF) stimulates tumor cells to release chemokines active in recruiting dendritic cells. (PubMed id 10702399)9 Scarpino S....Ruco L.P. (2000)
    339. Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes. (PubMed id 10934220)9 Tilton B....Thelen M. (2000)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6364 HGNC: 10619 AceView: CCL20 Ensembl:ENSG00000115009 euGenes: HUgn6364
    ECgene: CCL20 Kegg: 6364 H-InvDB: CCL20

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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    About This Section
    NameDescription
    PharmGKB entry for CCL20 Pharmacogenomics, SNPs, Pathways
    Wikipedia http://en.wikipedia.org/wiki/CCL20

    (Patent information from GeneIP,
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    Patent Information for CCL20 gene:
    Search GeneIP for patents involving CCL20

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