CCL18 Gene

Aliases
for CCL18 gene

Previous GC identifers: GC17P034161 GC17P036427 GC17P034537 GC17P031415 GC17P030576

Summaries
for CCL18 gene

Genomic Views
for CCL18 gene

RefSeq DNA sequence:

NC_000017.11  NC_018928.2  NT_010783.16  NT_187614.1  NT_187661.1  

SwitchGear Promoter luciferase reporter plasmid: CCL18 promoter sequence

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCL18

CCL18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P034391:  view genomic region     (about GC identifiers)

Proteins
for CCL18 gene

Explore the universe of human proteins at neXtProt for CCL18: NX_P55774

Explore proteomics data for CCL18 at MOPED

Post-translational modifications: 

CCL18 Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	R&D Systems Recombinant & Natural Proteins for CCL18 (CCL18/PARC)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein for CCL18 OriGene Protein Over-expression Lysate for CCL18 OriGene MassSpec for CCL18 OriGene Custom Protein Services for CCL18
	GenScript Purified and Recombinant Proteins for CCL18
	Novus Biologicals CCL18 Proteins Novus Biologicals CCL18 Lysate
	Sino Biological Recombinant Protein for CCL18 Browse Sino Biological Cell Lysates
	ProSpec Recombinant Protein for CCL18
	Browse Proteins at Cloud-Clone Corp.

CCL18 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	R&D Systems Antibodies for CCL18 (CCL18/PARC)
	Browse OriGene Antibodies OriGene Custom Antibody Services for CCL18
	Novus Biologicals CCL18 Antibodies
	Search for Antibodies for CCL18 at Abcam
	Browse Antibodies at Cloud-Clone Corp.
	ThermoFisher Antibodies for CCL18
	LSBio Antibodies in human, mouse, rat for CCL18

CCL18 Assay Products:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for CCL18
	R&D Systems ELISAs for CCL18 (CCL18/PARC)         (see all)
	GenScript Custom Assay Services for CCL18
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs at Cloud-Clone Corp. Browse CLIAs at Cloud-Clone Corp.

Domains /
Families
for CCL18 gene

ProtoNet protein and cluster: P55774

CCL18 for domains           About GeneDecksing

Function
for CCL18 gene

     Gene Ontology (GO): 2 molecular function terms:    About this table

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCL18

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCL18

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCL18

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CCL18

miRNA Products:		Block miRNA regulation of human, mouse, rat CCL18 using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate CCL18
		SwitchGear 3'UTR luciferase reporter plasmid: CCL18 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for CCL18
		Predesigned siRNA for gene silencing in human, mouse, rat CCL18

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for CCL18

Clone Products:		OriGene clones in human, mouse for CCL18 (see all 5) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CCL18 (NM_002988)
		Sino Biological Human cDNA Clone for CCL18
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCL18
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCL18

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for CCL18
		Browse ESI BIO Cell Lines and PureStem Progenitors for CCL18

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCL18

Localization
for CCL18 gene

Subcellular locations from COMPARTMENTS: 

Compartment	Confidence
extracellular	5
nucleus	1

About this image

Gene Ontology (GO): 2 cellular component terms:    About this table

Pathways & Interactions
for CCL18 gene

	SuperPath	Selected contained pathways About (see all per SuperPath)
1	PEDF Induced Signaling	MIF Regulation of Innate Immune Cells 0.94 NFAT Signaling and Lymphocyte Interactions 0.57 MIF Mediated Glucocorticoid Regulation 0.94 PGC1Alpha Pathway 0.51 PEDF Induced Signaling 0.73 STAT3 Pathway 0.47 all-trans-Retinoic Acid Signaling in Brain 0.71 Endothelin-1 Signaling Pathway 0.46
2	Chemokine Signaling	Chemokine signaling pathway 0.33 Chemokine Signaling 0.33
3	TGF-Beta Pathway	TGF-Beta Pathway 0.60 JNK Pathway 0.51 MAPK Family Pathway 0.60 Regulation of eIF4 and p70S6K 0.43 JAK-STAT Pathway 0.57 SOCS Pathway 0.40
4	Akt Signaling	Akt Signaling 0.60 Tec Kinases Signaling 0.55 p38 Signaling 0.60
5	ERK Signaling	Rho Family GTPases 0.61 Molecular Mechanisms of Cancer 0.51 ERK Signaling 0.61

1 R&D Systems Pathway for CCL18

Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions

Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for CCL18

	Endothelin-1 Signaling Pathway
	Molecular Mechanisms of Cancer
	Antioxidant Action of Vitamin-C
	NFAT Signaling and Lymphocyte Interactions
	JNK Pathway

2 Kegg Pathways  (Kegg details for CCL18)

	Cytokine-cytokine receptor interaction
	Chemokine signaling pathway

Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

Drugs & Compounds
for CCL18 gene

Transcripts
for CCL18 gene

Expression
for CCL18 gene

CCL18 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GATCAATCAG

About this image

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for CCL18
		Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CCL18
		QuantiTect SYBR Green Assays in human, mouse, rat CCL18
		QuantiFast Probe-based Assays in human, mouse, rat CCL18

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCL18

Orthologs
for CCL18 gene

Paralogs
for CCL18 gene

Paralogs for CCL18 gene

CCL15²  CCL16²  CCL14²  CCL4L1²  CCL3L1²  CCL4L2²  CCL26²  CCL3²  

CCL5²  CCL23²  CCL3L3²  CCL4²  CCL15-CCL14²  

Selected SIMAP similar genes for CCL18 using alignment to 1 protein entry:     CCL18_HUMAN(see all similar genes):

CCL14    CCL3    CCL3L1    CCL3L3    CCL23    CCL4

CCL4L2    LOC728835    CCL4L1    CCL2    CCL13    CCL15

CCL16    CCL24    CCL5    CX3CL1    CCL26    CCL7

CCL18 for paralogs           About GeneDecksing

Genomic Variants
for CCL18 gene

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs355110821,2	C	--	34395689(+)	TTTTA-/AAAAAA	1	--	int1		0	--	--	--	--
rs3770536801,2	--	--	34395745(+)	TTTTT-/TCAGGT	1	--	int1		0	--	--	--	--

HapMap Linkage Disequilibrium report for CCL18 (34391640 - 34399392 bp)

Structural Variations
     Database of Genomic Variants (DGV) 8 variations for CCL18:    About this table    

Variant ID	Type	Subtype	PubMed ID
nsv833427	CNV	Loss	17160897
dgv120e55	CNV	Gain	17911159
nsv833424	CNV	Gain	17160897
nsv428340	CNV	Gain	18775914
dgv945e1	CNV	Complex	17122850
dgv946e1	CNV	Complex	17122850
dgv947e1	CNV	Complex	17122850
dgv948e1	CNV	Complex	17122850

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing CCL18

DNA2.0 Custom Variant and Variant Library Synthesis for CCL18

Disorders / Diseases
for CCL18 gene

Selected diseases for CCL18

Congresses - knowledge worth sharing:

The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014

Selected Novoseek inferred disease relationships for CCL18 gene (see all 15)    About this table

Publications
for CCL18 gene

PubMed articles for CCL18 gene, integrated from 10 sources (see all 154) (see top 10): (articles sorted by number of sources associating them with CCL18)

Utopia: connect your pdf to the dynamic world of online information

1. A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes. (PubMed id 9233607)^{1, 2, 3, 9} Hieshima K.... Nomiyama H. (J. Immunol. 1997)
2. Chemokine PARC gene (SCYA18) generated by fusion of two MIP- 1alpha/LD78alpha-like genes. (PubMed id 10049593)^{1, 2, 3, 9} Tasaki Y.... Nomiyama H. (Genomics 1999)
3. Selective induction of CCL18/PARC by staphylococcal enterotoxins in mononuclear cells and enhanced levels in septic and rheumatoid arthritis. (PubMed id 11745396)^{1, 2, 9} Schutyser E.... Van Damme J. (Eur. J. Immunol. 2001)
4. Genomic organization and biological characterization of the novel human CC chemokine DC-CK-1/PARC/MIP-4/SCYA18. (PubMed id 10087196)^{1, 2, 9} Guan P.... McColl S.R. (Genomics 1999)
5. A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells. (PubMed id 9192897)^{1, 2, 9} Adema G.J....Figdor C.G. (Nature 1997)
6. Alternative macrophage activation-associated CC-chemokine-1, a novel structural homologue of macrophage inflammatory protein-1 alpha with a Th2-associated expression pattern. (PubMed id 9570561)^{1, 2, 9} Kodelja V.... Goerdt S. (J. Immunol. 1998)
7. Risk of meningioma and common variation in genes related to innate immunity. (PubMed id 20406964)^{1, 4} Rajaraman P....Inskip P.D. (amp 2010)
8. Polymorphisms in innate immunity genes and risk of childhood leukemia. (PubMed id 20438785)^{1, 4} Han S....Kang D. (Hum. Immunol. 2010)
9. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)^{1, 4} Bailey S.D....Anand S. (Diabetes Care 2010)
10. Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. (PubMed id 20503287)^{1, 4} Schuurhof A....Janssen R. (Pediatr. Pulmonol. 2010)
11. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923)^{1, 4} Siezen C.L....Janssen R. (Pediatr. Infect. Dis. J. 2009)
12. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. (PubMed id 17703412)^{1, 4} Janssen R....Hoebee B. (J. Infect. Dis. 2007)
13. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
14. Identification of biologically active chemokine isoforms from ascitic fluid and elevated levels of CCL18/pulmonary and activation-regulated chemokine in ovarian carcinoma. (PubMed id 11978786)^{1, 2} Schutyser E.... Van Damme J. (J. Biol. Chem. 2002)
15. The chemokine information source: identification and characterization of novel chemokines using the WorldWideWeb and expressed sequence tag databases. (PubMed id 9129202)^{1, 2} Wells T.N.C. and Peitsch M.C. (J. Leukoc. Biol. 1997)
16. Eosinophils and monocytes produce pulmonary and activation-regulated chemokine, which activates cultured monocytes/macrophages. (PubMed id 12716654)^{1, 9} Schraufstatter I....DiScipio R.G. (Am. J. Physiol. Lung Cell Mol. Physiol. 2004)
17. CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure. (PubMed id 15494534)^{1, 9} Pivarcsi A....Homey B. (J. Immunol. 2004)
18. Increased expression of CC chemokine ligand 18 in extrinsic atopic dermatitis patients. (PubMed id 17979978)^{1, 9} Park C.O....Lee K.H. (Exp. Dermatol. 2008)
19. Plasma chitotriosidase and CCL18 as surrogate markers for granulomatous macrophages in sarcoidosis. (PubMed id 19808030)^{1, 9} Boot R.G....Aerts J.M. ( international journal of clinical chemistry 2010)
20. Expression and regulation of CCL18 in synovial fluid neutrophils of patients with rheumatoid arthritis. (PubMed id 17875202)^{1, 9} Auer J....Beuscher H.U. (amp 2007)
21. CC chemokine ligand-5 (CCL5/RANTES) and CC chemokine ligand-18 (CCL18/PARC) are specific markers of refractory unstable angina pectoris and are transiently raised during severe ischemic symptoms. (PubMed id 17909104)^{1, 9} Kraaijeveld A.O....Biessen E.A. (Circulation 2007)
22. CCL18: a urinary marker of Gaucher cell burden in Gaucher patients. (PubMed id 16736095)^{1, 9} Boot R.G....Aerts J.M. (J. Inherit. Metab. Dis. 2006)
23. Plasma chitotriosidase and CCL18: early biochemical surrogate markers in type B Niemann-Pick disease. (PubMed id 15702402)^{1, 9} Brinkman J....Aerts J.M. (J. Inherit. Metab. Dis. 2005)
24. Pulmonary and activation-regulated chemokine stimulates collagen production in lung fibroblasts. (PubMed id 12805086)^{1, 9} Atamas S.P....White B. (Am. J. Respir. Cell Mol. Biol. 2003)
25. Expression of the chemokine PARC mRNA in bronchoalveolar cells of patients with sarcoidosis. (PubMed id 12161279)^{1, 9} Mrazek F....Petrek M. (Immunol. Lett. 2002)
26. Protein microarray analysis in patients with asthma: elevation of the chemokine PARC/CCL18 in sputum. (PubMed id 19017877)^{1, 9} Kim H.B....Kita H. (Chest 2009)
27. CC-chemokine ligand 18/pulmonary activation-regulated chemokine expression in the CNS with special reference to traumatic brain injuries and neoplastic disorders. (PubMed id 19958819)^{1, 9} Chang C.Y....Wu C.H. (Neuroscience 2010)
28. Upregulation of CC chemokine ligand 18 and downregulation of CX3C chemokine receptor 1 expression in human T-cell leukemia virus type 1-associated lymph node lesions: Results of chemokine and chemokine receptor DNA chip analysis. (PubMed id 17900259)^{1, 9} Shimizu K....Ohshima K. (Cancer Sci. 2007)
29. Genetic variation in the CCL18-CCL3-CCL4 chemokine gene cluster influences HIV Type 1 transmission and AIDS disease progression. (PubMed id 16773571)^{1, 9} Modi W.S....Winkler C. (Am. J. Hum. Genet. 2006)
30. CCL18 production is decreased in alveolar macrophages from cigarette smokers. (PubMed id 19357939)^{1, 9} Kollert F....Prasse A. (Inflammation 2009)
31. Early cutaneous gene transcription changes in adult atopic dermatitis and potential clinical implications. (PubMed id 17181634)^{1, 9} Plager D.A....Pittelkow M.R. (Exp. Dermatol. 2007)
32. A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18. (PubMed id 16415274)^{1, 9} Prasse A....Zissel G. (Am. J. Respir. Crit. Care Med. 2006)
33. Genome-wide association study of lung function phenotypes in a founder population. (PubMed id 23932459)¹ Yao T.C....Ober C. (J. Allergy Clin. Immunol. 2014)
34. Nir1 promotes invasion of breast cancer cells by binding to chemokine (C-C motif) ligand 18 through the PI3K/Akt/GSK3I^/Snail signalling pathway. (PubMed id 24001613)¹ Zhang B....Qi Y. (Eur. J. Cancer 2013)
35. The disulfide bond between cysteine 10 and cysteine 34 is required for CCL18 activity. (PubMed id 23742785)² Legendre B....Lassalle P. (Cytokine 2013)
36. CC-chemokine ligand 18 induces epithelial to mesenchymal transition in lung cancer A549 cells and elevates the invasive potential. (PubMed id 23349697)¹ Ploenes T....Zissel G. (PLoS ONE 2013)
37. CCL18 as an independent favorable prognostic biomarker in patients with colorectal cancer. (PubMed id 23433718)¹ Yuan R....Lan P. (J. Surg. Res. 2013)
38. Segmental allergen challenge enhances chitinase activity and levels of CCL18 in mild atopic asthma. (PubMed id 23331560)¹ Gavala M.L....Jarjour N.N. (Clin. Exp. Allergy 2013)
39. Role of CCL18 in asthma and lung immunity. (PubMed id 23786278)¹ Tsicopoulos A....Chenivesse C. (Clin. Exp. Allergy 2013)
40. Can serum surfactant protein D or CC-chemokine ligand 18 predict outcome of interstitial lung disease in patients with early systemic sclerosis? (PubMed id 23588945)¹ Elhaj M....Assassi S. (J. Rheumatol. 2013)
41. Increased CCL18 expression in patients with cutaneous T-cell lymphoma: association with disease severity and prognosis. (PubMed id 22404649)¹ Miyagaki T....Sato S. (J Eur Acad Dermatol Venereol 2013)
42. Identification of human CCR8 as a CCL18 receptor. (PubMed id 23999500)¹ Islam S.A....Luster A.D. (J. Exp. Med. 2013)
43. Gene expression profiles in paired gingival biopsies from periodontitis-affected and healthy tissues revealed by massively parallel sequencing. (PubMed id 23029519)¹ Davanian H....Yucel-Lindberg T. (PLoS ONE 2012)
44. CCL18 in a multiplex urine-based assay for the detection of bladder cancer. (PubMed id 22629457)¹ Urquidi V....Goodison S. (PLoS ONE 2012)
45. Enhanced production of CCL18 by tolerogenic dendritic cells is associated with inhibition of allergic airway reactivity. (PubMed id 23102918)¹ Bellinghausen I....Saloga J. (J. Allergy Clin. Immunol. 2012)
46. Serum level of CC-chemokine ligand 18 is increased in patients with non-small-cell lung cancer and correlates with survival time in adenocarcinomas. (PubMed id 22848587)¹ PlAPnes T....Zissel G. (PLoS ONE 2012)
47. The chemokine CCL18 causes maturation of cultured monocytes to macrophages in the M2 spectrum. (PubMed id 22117697)¹ Schraufstatter I.U....Discipio R.G. (Immunology 2012)
48. Increased expression of CC chemokine ligand 18 in patients with chronic rhinosinusitis with nasal polyps. (PubMed id 21943944)¹ Peterson S....Kato A. (J. Allergy Clin. Immunol. 2012)
49. Chemokines CCL3/MIP1I+, CCL5/RANTES and CCL18/PARC are independent risk predictors of short-term mortality in patients with acute coronary syndromes. (PubMed id 23029252)¹ de Jager S.C....Biessen E.A. (PLoS ONE 2012)
50. CCL18 -- potential biomarker of fibroinflammatory activity in chronic periaortitis. (PubMed id 22589264)¹ Kollert F....Warnatz K. (J. Rheumatol. 2012)
51. Pulmonary CCL18 recruits human regulatory T cells. (PubMed id 22649201)¹ Chenivesse C....Tsicopoulos A. (J. Immunol. 2012)
52. Expression of CCL18 and interleukin-6 in the plasma of breast cancer patients as compared with benign tumor patients and healthy controls. (PubMed id 22203932)¹ NariALa D....Anghel A. (Rom J Morphol Embryol 2011)
53. Evaluation of proteomics-identified CCL18 and CXCL1 as circulating tumor markers for differential diagnosis between ovarian carcinomas and benign pelvic masses. (PubMed id 21928244)¹ Wang Q....Li L. (Int. J. Biol. Markers 2011)
54. CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3. (PubMed id 21481794)¹ Chen J....Song E. (Cancer Cell 2011)
55. Serum CC chemokine ligand-18 predicts lung disease worsening in systemic sclerosis. (PubMed id 21778167)¹ Tiev K.P....Dinh-Xuan A.T. (Eur. Respir. J. 2011)
56. Alternative activation of macrophages in human peritoneum: implications for peritoneal fibrosis. (PubMed id 21324976)¹ BellA^n T....Bajo M.A. (Nephrol. Dial. Transplant. 2011)
57. CCL2, CCL18 and sIL-4R in renal, meningeal and pulmonary TB; a 2 year study of patients and contacts. (PubMed id 21251883)¹ Mendez A....Rook G.A. (Tuberculosis (Edinb) 2011)
58. Exploring CCL18, eczema severity and atopy. (PubMed id 21539615)¹ Hon K.L....Leung T.F. (Pediatr Allergy Immunol 2011)
59. Chemokine CCL18 predicts intraventricular hemorrhage in very preterm infants. (PubMed id 20608885)¹ Kallankari H....Hallman M. (Ann. Med. 2010)
60. Cardiovascular determinants and prognostic significance of CC Chemokine Ligand-18 (CCL18/PARC) in patients with stable coronary artery disease. (PubMed id 20674579)¹ De Sutter J....Van Damme J. (J. Mol. Cell. Cardiol. 2010)
61. Clinical utility of circulating matrix metalloproteinase-7 (MMP-7), CC chemokine ligand 18 (CCL18) and CC chemokine ligand 11 (CCL11) as markers for diagnosis of epithelial ovarian cancer. (PubMed id 19937162)¹ Zohny S.F. and Fayed S.T. (Med. Oncol. 2010)
62. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)¹ Davila S....Seielstad M. (Genes Immun. 2010)
63. Attenuation of CXCR4 responses by CCL18 in acute lymphocytic leukemia B cells. (PubMed id 20568229)¹ Catusse J....Burger M. (J. Cell. Physiol. 2010)
64. Expression of chemokine (C-C motif) ligand 18 in human macrophages and atherosclerotic plaques. (PubMed id 19036375)¹ HAogg D.A....Svensson P.A. (Atherosclerosis 2009)
65. Common variation in genes related to innate immunity and risk of adult glioma. (PubMed id 19423540)¹ Rajaraman P....Chanock S.J. (amp 2009)
66. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (Am. J. Hum. Genet. 2009)
67. Human protein factory for converting the transcriptome into an in vitro-expressed proteome. (PubMed id 19054851)² Goshima N.... Nomura N. (Nat. Methods 2008)
68. CCL18 as an indicator of pulmonary fibrotic activity in idiopathic interstitial pneumonias and systemic sclerosis. (PubMed id 17469163)¹ Prasse A....MA1ller-Quernheim J. (Arthritis Rheum. 2007)
69. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)¹ Lamesch P.... Vidal M. (Genomics 2007)
70. Novel insights in the regulation of CCL18 secretion by monocytes and dendritic cells via cytokines, toll-like receptors and rheumatoid synovial fluid. (PubMed id 16984635)¹ van Lieshout A.W....Radstake T.R. (BMC Immunol. 2006)
71. Involvement of CCL18 in allergic asthma. (PubMed id 16670340)¹ de NadaA^ P....Tsicopoulos A. (J. Immunol. 2006)
72. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)¹ Stelzl U.... Wanker E.E. (Cell 2005)
73. CCL18 is expressed in atopic dermatitis and mediates skin homing of human memory T cells. (PubMed id 15661937)¹ GA1nther C....Carballido J.M. (J. Immunol. 2005)
74. PARC/CCL18 is a plasma CC chemokine with increased levels in childhood acute lymphoblastic leukemia. (PubMed id 14578205)¹ Struyf S....Laureys G. (Am. J. Pathol. 2003)
75. The dendritic cell-specific chemokine, dendritic cell-derived CC chemokine 1, enhances protective cell-mediated immunity to murine malaria. (PubMed id 12626578)¹ Bruna-Romero O....Tsuji M. (J. Immunol. 2003)
76. Unique regulation of CCL18 production by maturing dendritic cells. (PubMed id 12646652)¹ Vulcano M....Sozzani S. (J. Immunol. 2003)
77. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
78. (PubMed id )² 
79. Involvement of CC chemokine ligand 18 (CCL18) in normal and pathological processes. (PubMed id 15784687)⁹ Schutyser E....Van Damme J. (J. Leukoc. Biol. 2005)
80. Pseudoexons and regulatory elements in the genomic sequence of the beta-chemokine, alternative macrophage activation-associated CC-chemokine (AMAC)-1. (PubMed id 10671296)⁹ Politz O....Goerdt S. (Cytokine 2000)
81. Complex regulation of pulmonary inflammation and fibrosis by CCL18. (PubMed id 17569779)⁹ Pochetuhen K....Atamas S.P. (Am. J. Pathol. 2007)
82. Serum pulmonary and activation-regulated chemokine/CCL18 levels in patients with systemic sclerosis: a sensitive indicator of active pulmonary fibrosis. (PubMed id 16142750)⁹ Kodera M....Sato S. (Arthritis Rheum. 2005)
83. The dendritic cell-specific CC-chemokine DC-CK1 is expressed by germinal center dendritic cells and attracts CD38-negative mantle zone B lymphocytes. (PubMed id 11207283)⁹ Lindhout E....Adema G.J. (J. Immunol. 2001)
84. Expression and cellular localization of the CC chemokines PARC and ELC in human atherosclerotic plaques. (PubMed id 10027395)⁹ Reape T.J....Groot P.H. (Am. J. Pathol. 1999)
85. Mycobacterium tuberculosis induces CCL18 expression in human macrophages. (PubMed id 18959625)⁹ Ferrara G....Condos R. (Scand. J. Immunol. 2008)
86. Mechanism of DNA segregation in prokaryotes: replicon pairing by parC of plasmid R1. (PubMed id 9671715)⁹ Jensen R.B....Gerdes K. (Proc. Natl. Acad. Sci. U.S.A. 1998)
87. PKCalpha mediates CCL18-stimulated collagen production in pulmonary fibroblasts. (PubMed id 16601239)⁹ Luzina I.G....Atamas S.P. (Am. J. Respir. Cell Mol. Biol. 2006)
88. Clinical evaluation of chemokine and enzymatic biomarkers of Gaucher disease. (PubMed id 16125420)⁹ Deegan P.B....Cox T.M. (amp 2005)
89. Langerhans cells do not express alternative macrophage activation-associated CC chemokine (AMAC)-1. (PubMed id 9851514)⁹ Kodelja V....Goerdt S. (Res. Immunol. 1998)
90. [Evaluation of the chemokine variation in tears of contact lens wearers]. (PubMed id 17025230)⁹ Iwasaki Y....Sawa M. (Nippon Ganka Gakkai Zasshi 2006)
91. C-C chemokine receptor 3 antagonism by the beta-chemokine macrophage inflammatory protein 4, a property strongly enhanced by an amino-terminal alanine-methionine swap. (PubMed id 10640766)⁹ Nibbs R.J....Graham G.J. (J. Immunol. 2000)
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