Aliases for CCL18 Gene
Aliases for CCL18 Gene
- C-C Motif Chemokine Ligand 18 2 3 5
- Small Inducible Cytokine Subfamily A (Cys-Cys), Member 18, Pulmonary And Activation-Regulated 2 3
- Chemokine (C-C Motif) Ligand 18 (Pulmonary And Activation-Regulated) 2 3
- Alternative Macrophage Activation-Associated CC Chemokine 1 3 4
- Pulmonary And Activation-Regulated Chemokine 3 4
- Macrophage Inflammatory Protein 4 3 4
- Dendritic Cell Chemokine 1 3 4
- CC Chemokine PARC 3 4
- SCYA18 3 4
- AMAC-1 3 4
- DC-CK1 3 4
- AMAC1 3 4
- DCCK1 3 4
External Ids for CCL18 Gene
- HGNC: 10616
- Entrez Gene: 6362
- Ensembl: ENSG00000275385
- OMIM: 603757
- UniProtKB: P55774
Previous HGNC Symbols for CCL18 Gene
- SCYA18
Previous GeneCards Identifiers for CCL18 Gene
- GC17P034161
- GC17P036427
- GC17P034537
- GC17P031415
- GC17P034391
- GC17P030576
Summaries for CCL18 Gene
-
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq, Sep 2014]
GeneCards Summary for CCL18 Gene
CCL18 (C-C Motif Chemokine Ligand 18) is a Protein Coding gene. Diseases associated with CCL18 include Gaucher's Disease and Pulmonary Fibrosis. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include chemokine activity. An important paralog of this gene is CCL3.
UniProtKB/Swiss-Prot for CCL18 Gene
-
Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses.
Additional gene information for CCL18 Gene
- Monarch Initiative
- Search for CCL18 at DataMed
- Search for CCL18 at HumanCyc
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCL18 Gene
Genomics for CCL18 Gene
GeneHancer (GH) Regulatory Elements for CCL18 Gene
Regulatory Element Products
Genomic Locations for CCL18 Gene
- chr17:36,064,272-36,072,032
- (GRCh38/hg38)
- Size:
- 7,761 bases
- Orientation:
- Plus strand
- chr17:34,391,640-34,399,392
- (GRCh37/hg19)
Genomic View for CCL18 Gene
- Cytogenetic band:
-
- 17q12 by Ensembl
- 17q12 by Entrez Gene
- 17q12 by HGNC


RefSeq DNA sequence for CCL18 Gene
Proteins for CCL18 Gene
-
Protein details for CCL18 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P55774-CCL18_HUMAN
- Recommended name:
- C-C motif chemokine 18
- Protein Accession:
- P55774
- B5BUM2
- Q53X71
Protein attributes for CCL18 Gene
- Size:
- 89 amino acids
- Molecular mass:
- 9849 Da
- Quaternary structure:
- No Data Available
Protein Expression for CCL18 Gene
Post-translational modifications for CCL18 Gene
- The Cys-30/Cys-54 disulfide bond is required for activity.
Other Protein References for CCL18 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for CCL18 (CCL18/PARC)
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-
Abcam antibodies for CCL18
-
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- Invitrogen Antibodies for CCL18
- antibodies-online: Search results for 63 available AMAC1 Antibodies ranked by validation data
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-
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- ABIN256469
- ABIN5555099
- ABIN117956
- ABIN396042
- ABIN2666359
- ABIN250681
- ABIN4343683
- ABIN4343682
- ABIN213963
- ABIN152323
- ABIN256469
- ABIN5555099
- ABIN117956
- ABIN396042
- ABIN2666359
- ABIN250681
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- Search GeneTex for Antibodies for CCL18
-
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- Sino Biological Antibodies for CCL18
Protein Products
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-
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- Search GeneTex for Proteins for CCL18
-
Abcam proteins for CCL18
Assay Products
-
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-
Abcam assays for CCL18
No data available for DME Specific Peptides for CCL18 Gene
Domains & Families for CCL18 Gene
Gene Families for CCL18 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Plasma proteins
- Predicted secreted proteins
Protein Domains for CCL18 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CCL18 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P55774- Family:
-
- Belongs to the intercrine beta (chemokine CC) family.
Function for CCL18 Gene
Molecular function for CCL18 Gene
- UniProtKB/Swiss-Prot Function:
- Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses.
- UniProtKB/Swiss-Prot Induction:
- Specifically induced in macrophages by IL4/interleukin-4, IL13/interleukin-13, and IL10/interleukin-10. Expression is inhibited by IFNG/IFN-gamma while glucocorticoids exert a slightly positive synergistic effect in combination with IL4/interleukin-4. Strongly induced in several human cell lines, including monocytic U-937 cells, by phorbol myristate acetate (PMA). Induced in PBMC by staphylococcal enterotoxins SEA and SEB.
Phenotypes From GWAS Catalog for CCL18 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005125 | cytokine activity | IEA | -- |
GO:0005515 | protein binding | IPI | 21481794 |
GO:0008009 | chemokine activity | IBA,TAS | -- |
GO:0048020 | CCR chemokine receptor binding | IBA | -- |
Phenotypes for CCL18 Gene
- GenomeRNAi human phenotypes for CCL18:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCL18
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CCL18 gene
-
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- Search ViGene Biosciences for CCL18
CRISPR Products
-
OriGene CRISPR knockouts for CCL18
- genomics-online: gRNA clones - Search results for 56 available AMAC1 gene related products
- Overview of 56 available AMAC1 gene related products
-
Recommended
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- pCMV6-AC-GFP
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- pDONR223
- pLenti-C-mGFP
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- pCMV6-Entry
- Applied Biological Materials CRISPR for CCL18
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCL18
- GenScript: Design CRISPR guide RNA sequences for CCL18
miRNA Products
- Search ViGene Biosciences for CCL18
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CCL18
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- genomics-online: shRNA clones - Search results for 56 available AMAC1 gene related products
- Overview of 56 available AMAC1 gene related products
-
Recommended
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
-
ViGene Biosciences ready-to-package AAV shRNAs for CCL18 gene
Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for 56 available AMAC1 gene related products
- Overview of 56 available AMAC1 gene related products
-
Recommended
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- orf clones - Search results for 56 available AMAC1 gene related products
- Overview of 56 available AMAC1 gene related products
-
Recommended
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- Applied Biological Materials Clones for CCL18
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for CCL18
-
ViGene Biosciences adenoviral particle packaged cDNA for CCL18 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CCL18 gene
-
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCL18 Gene
Localization for CCL18 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CCL18 Gene
- Secreted.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | IEA | -- |
GO:0005615 | extracellular space | IBA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CCL18 Gene
Pathways & Interactions for CCL18 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | PEDF Induced Signaling |
.61
|
.47
|
2 | TGF-Beta Pathway |
.60
.57
|
.51
.40
|
3 | Akt Signaling |
.60
.60
|
|
4 | ERK Signaling |
.61
|
|
5 | CCR5 Pathway in Macrophages |
Pathways by source for CCL18 Gene
2 KEGG pathways for CCL18 Gene
1 R&D Systems pathway for CCL18 Gene
27 Qiagen pathways for CCL18 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0002548 | monocyte chemotaxis | IBA | -- |
GO:0006935 | chemotaxis | TAS | 9192897 |
GO:0006954 | inflammatory response | IBA | -- |
GO:0006955 | immune response | TAS | 9192897 |
GO:0007154 | cell communication | TAS | 9192897 |
No data available for SIGNOR curated interactions for CCL18 Gene
Transcripts for CCL18 Gene
mRNA/cDNA for CCL18 Gene
- (1) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (73) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CCL18 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CCL18
- genomics-online: gRNA clones - Search results for 56 available AMAC1 gene related products
- Overview of 56 available AMAC1 gene related products
-
Recommended
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- Applied Biological Materials CRISPR for CCL18
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CCL18
- GenScript: Design CRISPR guide RNA sequences for CCL18
miRNA Products
- Search ViGene Biosciences for CCL18
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CCL18
- Browse OriGene Inhibitory RNA Products For CCL18
- genomics-online: shRNA clones - Search results for 56 available AMAC1 gene related products
- Overview of 56 available AMAC1 gene related products
-
Recommended
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
-
ViGene Biosciences ready-to-package AAV shRNAs for CCL18 gene
Clone Products
- Sino Biological Human cDNA Clone for CCL18
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CCL18
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCL18
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for 56 available AMAC1 gene related products
- Overview of 56 available AMAC1 gene related products
-
Recommended
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- orf clones - Search results for 56 available AMAC1 gene related products
- Overview of 56 available AMAC1 gene related products
-
Recommended
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- Applied Biological Materials Clones for CCL18
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for CCL18 Gene
mRNA differential expression in normal tissues according to GTEx for CCL18 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCL18 Gene
NURSA nuclear receptor signaling pathways regulating expression of CCL18 Gene:
CCL18SOURCE GeneReport for Unigene cluster for CCL18 Gene:
Hs.143961mRNA Expression by UniProt/SwissProt for CCL18 Gene:
P55774-CCL18_HUMANEvidence on tissue expression from TISSUES for CCL18 Gene
- Lung(4.6)
- Lymph node(4.6)
- Spleen(4.5)
- Blood(4.4)
Primer Products
-
OriGene qPCR primer pairs for CCL18
- genomics-online: primer clones - Search results for 56 available CUL9 gene related products
- Overview of 56 available CCL18 gene related products
-
Recommended
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
- pRS
- pCMV6-AC-GFP
- pPB-C-His
- pPB-N-His
- pPB-His-MBP
- pPB-His-GST
- pGFP-C-shLenti
- pGFP-V-RS
- pRFP-C-RS
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pCMV6-Entry
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCL18 Gene
Orthologs for CCL18 Gene
This gene was present in the common ancestor of human and chimp.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | CCL18 33 |
|
- Species where no ortholog for CCL18 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for CCL18 Gene
(27) SIMAP similar genes for CCL18 Gene using alignment to 1 proteins:
Variants for CCL18 Gene
SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000201843 | -- | 36,063,621(+) | G/A | upstream_transcript_variant | |
rs1000304885 | -- | 36,063,049(+) | A/G | upstream_transcript_variant | |
rs1000358603 | -- | 36,063,372(+) | C/G | upstream_transcript_variant | |
rs1000930741 | -- | 36,062,339(+) | G/T | upstream_transcript_variant | |
rs1001058493 | -- | 36,068,151(+) | T/G | intron_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv120e55 | CNV | gain | 17911159 |
dgv3143n100 | CNV | gain | 25217958 |
esv2762388 | CNV | gain+loss | 21179565 |
nsv1059795 | CNV | gain | 25217958 |
nsv574755 | CNV | gain | 21841781 |
nsv833424 | CNV | gain | 17160897 |
nsv833427 | CNV | loss | 17160897 |
Additional Variant Information for CCL18 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CCL18
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCL18 Gene
Disorders for CCL18 Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
gaucher's disease |
|
|
pulmonary fibrosis |
|
|
dermatitis, atopic |
|
|
sarcoidosis 1 |
|
|
pulmonary fibrosis, idiopathic |
|
|
Additional Disease Information for CCL18
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for CCL18 Gene
Publications for CCL18 Gene
- Chemokine PARC gene (SCYA18) generated by fusion of two MIP-1alpha/LD78alpha-like genes. (PMID: 10049593) Tasaki Y … Nomiyama H (Genomics 1999) 2 3 4 22 58
- A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes. (PMID: 9233607) Hieshima K … Nomiyama H (Journal of immunology (Baltimore, Md. : 1950) 1997) 2 3 4 22 58
- Selective induction of CCL18/PARC by staphylococcal enterotoxins in mononuclear cells and enhanced levels in septic and rheumatoid arthritis. (PMID: 11745396) Schutyser E … Van Damme J (European journal of immunology 2001) 3 4 22 58
- Genomic organization and biological characterization of the novel human CC chemokine DC-CK-1/PARC/MIP-4/SCYA18. (PMID: 10087196) Guan P … McColl SR (Genomics 1999) 3 4 22 58
- Alternative macrophage activation-associated CC-chemokine-1, a novel structural homologue of macrophage inflammatory protein-1 alpha with a Th2-associated expression pattern. (PMID: 9570561) Kodelja V … Goerdt S (Journal of immunology (Baltimore, Md. : 1950) 1998) 3 4 22 58
Products for CCL18 Gene
- R&D Systems Antibodies for CCL18 (CCL18/PARC)
- R&D Systems Proteins and Enzymes for CCL18 (CCL18/PARC)
- R&D Systems ELISAs, Luminex Assays, Proteome Profiler Antibody Arrays, and other biochemical assays for CCL18 (CCL18/PARC)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Custom Assay ServicesOriGene ELISA Kits for CCL18
- Search Origene for MassSpec and Protein Over-expression Lysates for CCL18
- Origene Custom Protein Services for CCL18
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CCL18
- Browse OriGene Inhibitory RNA Products For CCL18
- OriGene qPCR primer pairs for CCL18
- OriGene CRISPR knockouts for CCL18
- OriGene ORF clones in human for CCL18
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CCL18
- GenScript: Next-day shipping of latest version cDNA ORF clones for CCL18 in any vector
- GenScript Purified and Recombinant Proteins for CCL18
- GenScript Custom Purified and Recombinant Proteins Services for CCL18
- GenScript Custom Assay Services for CCL18
- GenScript Custom overexpressing Cell Line Services for CCL18
- GenScript: Design CRISPR guide RNA sequences for CCL18
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CCL18
- Sino Biological Human cDNA Clone for CCL18
- Sino Biological Recombinant Proteins for CCL18
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for CCL18
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for CCL18
- Novus Biologicals proteins and lysates for CCL18
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for CCL18
- Abcam proteins for CCL18
- Abcam assays for CCL18
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ProSpec Recombinant Proteins for CCL18
- Cloud-Clone Corp. Antibodies for CCL18
- Cloud-Clone Corp. Proteins for CCL18
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for CCL18
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for CCL18
- VectorBuilder custom plasmid, inducible vectors for CCL18
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CCL18
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 63 available CCL18 Antibodies ranked by validation data
- Compare Top CCL18 Antibodies
- Quality Products:
- ABIN117956
- ABIN5555099
- ABIN256469
- ABIN152323
- ABIN213963
- ABIN4343682
- ABIN4343683
- ABIN250681
- ABIN2666359
- ABIN396042
- ABIN117956
- ABIN5555099
- ABIN256469
- ABIN152323
- ABIN213963
- ABIN4343682
- ABIN4343683
- ABIN250681
- ABIN2666359
- ABIN396042
- ABIN117956
- ABIN5555099
- ABIN256469
- ABIN152323
- ABIN213963
- ABIN4343682
- ABIN4343683
- ABIN250681
- ABIN2666359
- ABIN396042
- antibodies-online: Search results for 43 available CCL18 Elisa Kits ranked by validation data
- Compare Top CCL18 Elisa Kits
- Quality Products:
- ABIN1672771
- ABIN627280
- ABIN5594247
- ABIN628443
- ABIN628791
- ABIN628094
- ABIN1558820
- ABIN1050203
- ABIN993624
- ABIN778164
- ABIN1672771
- ABIN627280
- ABIN5594247
- ABIN628443
- ABIN628791
- ABIN628094
- ABIN1558820
- ABIN1050203
- ABIN993624
- ABIN778164
- ABIN1672771
- ABIN627280
- ABIN5594247
- ABIN628443
- ABIN628791
- ABIN628094
- ABIN1558820
- ABIN1050203
- ABIN993624
- ABIN778164
- antibodies-online: Search results for 43 available CCL18 Proteins ranked by validation data
- Compare Top CCL18 Proteins
- Quality Products:
- ABIN3091085
- ABIN666793
- ABIN780720
- ABIN2726055
- ABIN1692045
- ABIN5509376
- ABIN2726054
- ABIN413647
- ABIN2002965
- ABIN4887820
- ABIN3091085
- ABIN666793
- ABIN780720
- ABIN2726055
- ABIN1692045
- ABIN5509376
- ABIN2726054
- ABIN413647
- ABIN2002965
- ABIN4887820
- ABIN3091085
- ABIN666793
- ABIN780720
- ABIN2726055
- ABIN1692045
- ABIN5509376
- ABIN2726054
- ABIN413647
- ABIN2002965
- ABIN4887820
- Search GeneTex for Antibodies for CCL18
- Search GeneTex for Proteins for CCL18
- ViGene Biosciences adenoviral particle packaged cDNA for CCL18 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CCL18 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CCL18 gene
- Search ViGene Biosciences for CCL18
- Santa Cruz Biotechnology (SCBT) Antibodies for CCL18
- Search Santa Cruz Biotechnology (SCBT) for CCL18 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CCL18
- Horizon Cell Lines for CCL18
- genomics-online: cdna clones - Search results for 56 available CCL18 gene related products
- Overview of 56 available CCL18 gene related products
- Recommended
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- orf clones - Search results for 56 available CCL18 gene related products
- Overview of 56 available CCL18 gene related products
- Recommended
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- genomics-online: gRNA clones - Search results for 56 available CCL18 gene related products
- Overview of 56 available CCL18 gene related products
- Recommended
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- genomics-online: primer clones - Search results for 56 available CCL18 gene related products
- Overview of 56 available CCL18 gene related products
- Recommended
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- genomics-online: shRNA clones - Search results for 56 available CCL18 gene related products
- Overview of 56 available CCL18 gene related products
- Recommended
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
- pCMV6-Entry
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pPB-His-GST
- pPB-His-MBP
- pPB-N-His
- pPB-C-His
- pCMV6-AC-GFP
- pRS
Sources for CCL18 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
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