CCL18 Gene

Aliases
for CCL18 gene

Previous GC identifers: GC17P034161 GC17P036427 GC17P034537 GC17P031415 GC17P030576

Summaries
for CCL18 gene

Genomic Views
for CCL18 gene

RefSeq DNA sequence:

NC_000017.10  NC_018928.2  NT_010799.15  

SwitchGear Promoter luciferase reporter plasmid: CCL18 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCL18

CCL18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P034391:  view genomic region     (about GC identifiers)

Proteins
for CCL18 gene

Explore the universe of human proteins at neXtProt for CCL18: NX_P55774

Explore proteomics data for CCL18 at MOPED 

CCL18 Protein expression data from MOPED¹, PaxDb² and MAXQB³ :    About this image 

	Browse Purified and Recombinant Proteins at EMD Millipore
	R&D Systems Recombinant & Natural Proteins for CCL18 (CCL18/PARC)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein for CCL18 OriGene Protein Over-expression Lysate for CCL18 OriGene MassSpec for CCL18  OriGene Custom Protein Services for CCL18
	GenScript Purified and Recombinant Proteins for CCL18
	Novus Biologicals CCL18 Proteins Novus Biologicals CCL18 Lysate
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	ProSpec Recombinant Protein for CCL18
	Browse Proteins at Cloud-Clone Corp.

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	R&D Systems Antibodies for CCL18 (CCL18/PARC)
	Browse OriGene Antibodies OriGene Custom Antibody Services for CCL18
	GenScript Custom Superior Antibodies Services for CCL18
	Novus Biologicals CCL18 Antibodies
	Abcam antibodies for CCL18
	Browse Antibodies at Cloud-Clone Corp.
	ThermoFisher Antibodies for CCL18
	LSBio Antibodies in human, mouse, rat for CCL18

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for CCL18
	R&D Systems ELISAs for CCL18 (CCL18/PARC)         (see all)
	GenScript Custom Assay Services for CCL18
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs at Cloud-Clone Corp.  Browse CLIAs at Cloud-Clone Corp.

Protein Domains /
Families
for CCL18 gene

ProtoNet protein and cluster: P55774

CCL18 for domains           About GeneDecksing

Function
for CCL18 gene

     Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

inGenious Targeting Laboratory - Custom generated mouse model solutions for CCL18

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CCL18

miRNA Products:
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CCL18
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CCL18
		SwitchGear 3'UTR luciferase reporter plasmid: CCL18 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for CCL18
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCL18
		Sirion Biotech Custom design and validation of potent shRNA sequences against CCL18

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for CCL18
			Sirion Biotech Customized adenovirus for overexpression of CCL18                      Customized adenovirus for potent knockdown of CCL18

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene clones in human, mouse for CCL18 (see all 5) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CCL18 (NM_002988)
		Sino Biological Human cDNA Clone for CCL18
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCL18
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCL18

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for CCL18
		Search LifeMap BioReagents cell lines for CCL18
		Sirion Biotech Customized stable knockdown cell line services for CCL18                      Customized inducible knockdown cell line services for CCL18                      Customized stable overexpressing cell line services for CCL18                      Customized inducible overexpressing cell line services for CCL18

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCL18

Pathways & Interactions
for CCL18 gene

	SuperPath	Selected contained pathways About (see all per SuperPath)
1	PEDF Induced Signaling	MIF Mediated Glucocorticoid Regulation 0.94 NFAT Signaling and Lymphocyte Interactions 0.57 MIF Regulation of Innate Immune Cells 0.94 PGC1Alpha Pathway 0.51 PEDF Induced Signaling 0.73 STAT3 Pathway 0.47 all-trans-Retinoic Acid Signaling in Brain 0.71 Endothelin-1 Signaling Pathway 0.46
2	Chemokine Signaling	Chemokine Signaling 0.33 Chemokine signaling pathway 0.33
3	TGF-Beta Pathway	TGF-Beta Pathway 0.60 JNK Pathway 0.51 MAPK Family Pathway 0.60 Regulation of eIF4 and p70S6K 0.43 JAK-STAT Pathway 0.57 SOCS Pathway 0.40
4	Akt Signaling	Akt Signaling 0.60 Tec Kinases Signaling 0.55 p38 Signaling 0.60
5	Rho Family GTPases	Rho Family GTPases 0.61 Molecular Mechanisms of Cancer 0.51 ERK Signaling 0.61

5/27 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CCL18

	Endothelin-1 Signaling Pathway
	Molecular Mechanisms of Cancer
	Antioxidant Action of Vitamin-C
	NFAT Signaling and Lymphocyte Interactions
	JNK Pathway

2         Kegg Pathways  (Kegg details for CCL18)

	Cytokine-cytokine receptor interaction
	Chemokine signaling pathway

Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

Drugs & Compounds
for CCL18 gene

Transcripts
for CCL18 gene

Expression
for CCL18 gene

CCL18 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GATCAATCAG

About this image

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for CCL18
		SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CCL18
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCL18
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCL18

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCL18

Orthologs
for CCL18 gene

Paralogs
for CCL18 gene

Paralogs for CCL18 gene

CCL15²  CCL16²  CCL14²  CCL4L1²  CCL3L1²  CCL4L2²  CCL26²  CCL3²  

CCL5²  CCL23²  CCL3L3²  CCL4²  CCL15-CCL14²  

18/27 SIMAP similar genes for CCL18 using alignment to 1 protein entry:     CCL18_HUMAN(see all similar genes):

CCL14    CCL3    CCL3L1    CCL3L3    CCL23    CCL4

CCL4L2    LOC728835    CCL4L1    CCL2    CCL13    CCL15

CCL16    CCL24    CCL5    CX3CL1    CCL26    CCL7

CCL18 for paralogs           About GeneDecksing

Genomic Variants
for CCL18 gene

2 SNPs in CCL18 are shown    About this table     

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs355110821,2	C	--	34395689(+)	TTTTA-/AAAAAA	1	--	int1		0	--	--	--	--
rs3770536801,2	--	--	34395745(+)	TTTTT-/TCAGGT	1	--	int1		0	--	--	--	--

HapMap Linkage Disequilibrium report for CCL18 (34391640 - 34399392 bp)

Structural Variations
     Database of Genomic Variants (DGV) 8 variations for CCL18:    About this table     

Variant ID	Type	Subtype	PubMed ID
nsv833427	CNV	Loss	17160897
dgv120e55	CNV	Gain	17911159
nsv833424	CNV	Gain	17160897
nsv428340	CNV	Gain	18775914
dgv945e1	CNV	Complex	17122850
dgv946e1	CNV	Complex	17122850
dgv947e1	CNV	Complex	17122850
dgv948e1	CNV	Complex	17122850

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCL18

DNA2.0 Custom Variant and Variant Library Synthesis for CCL18

Disorders / Diseases
for CCL18 gene

20/52 diseases for CCL18

Congresses - knowledge worth sharing:  

The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014

10/15 Novoseek inferred disease relationships for CCL18 gene (see all 15)    About this table

Publications
for CCL18 gene

PubMed articles for CCL18 gene, integrated from 9 sources (see all 148) (see top 10): (articles sorted by number of sources associating them with CCL18)

Utopia: connect your pdf to the dynamic world of online information

1. A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes. (PubMed id 9233607)^{1, 2, 3, 9} Hieshima K.... Nomiyama H. (1997)
2. Chemokine PARC gene (SCYA18) generated by fusion of two MIP- 1alpha/LD78alpha-like genes. (PubMed id 10049593)^{1, 2, 3, 9} Tasaki Y.... Nomiyama H. (1999)
3. Selective induction of CCL18/PARC by staphylococcal enterotoxins in mononuclear cells and enhanced levels in septic and rheumatoid arthritis. (PubMed id 11745396)^{1, 2, 9} Schutyser E.... Van Damme J. (2001)
4. Genomic organization and biological characterization of the novel human CC chemokine DC-CK-1/PARC/MIP-4/SCYA18. (PubMed id 10087196)^{1, 2, 9} Guan P.... McColl S.R. (1999)
5. A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells. (PubMed id 9192897)^{1, 2, 9} Adema G.J....Figdor C.G. (1997)
6. Alternative macrophage activation-associated CC-chemokine-1, a novel structural homologue of macrophage inflammatory protein-1 alpha with a Th2-associated expression pattern. (PubMed id 9570561)^{1, 2, 9} Kodelja V.... Goerdt S. (1998)
7. Risk of meningioma and common variation in genes rela ted to innate immunity. (PubMed id 20406964)^{1, 4} Rajaraman P....Inskip P.D. (2010)
8. Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)^{1, 4} Han S....Kang D. (2010)
9. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)^{1, 4} Bailey S.D....Anand S. (2010)
10. Interleukin-9 polymorphism in infants with respirator y syncytial virus infection: an opposite effect in boys and girls. (PubMed id 20503287)^{1, 4} Schuurhof A....Janssen R. (2010)
11. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923)^{1, 4} Siezen C.L....Janssen R. (2009)
12. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. (PubMed id 17703412)^{1, 4} Janssen R....Hoebee B. (2007)
13. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
14. Identification of biologically active chemokine isoforms from ascitic fluid and elevated levels of CCL18/pulmonary and activation-regulated chemokine in ovarian carcinoma. (PubMed id 11978786)^{1, 2} Schutyser E.... Van Damme J. (2002)
15. The chemokine information source: identification and characterization of novel chemokines using the WorldWideWeb and expressed sequence tag databases. (PubMed id 9129202)^{1, 2} Wells T.N.C. and Peitsch M.C. (1997)
16. Eosinophils and monocytes produce pulmonary and activation-regulated chemokine, which activates cultured monocytes/macrophages. (PubMed id 12716654)^{1, 9} Schraufstatter I....DiScipio R.G. (2004)
17. CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure. (PubMed id 15494534)^{1, 9} Pivarcsi A....Homey B. (2004)
18. Increased expression of CC chemokine ligand 18 in extrinsic atopic dermatitis patients. (PubMed id 17979978)^{1, 9} Park C.O....Lee K.H. (2008)
19. Plasma chitotriosidase and CCL18 as surrogate markers for granulomatous macrophages in sarcoidosis. (PubMed id 19808030)^{1, 9} Boot R.G....Aerts J.M. (2010)
20. Expression and regulation of CCL18 in synovial fluid neutrophils of patients with rheumatoid arthritis. (PubMed id 17875202)^{1, 9} Auer J....Beuscher H.U. (2007)
21. CC chemokine ligand-5 (CCL5/RANTES) and CC chemokine ligand-18 (CCL18/PARC) are specific markers of refractory unstable angina pectoris and are transiently raised during severe ischemic symptoms. (PubMed id 17909104)^{1, 9} Kraaijeveld A.O....Biessen E.A. (2007)
22. CCL18: a urinary marker of Gaucher cell burden in Gaucher patients. (PubMed id 16736095)^{1, 9} Boot R.G....Aerts J.M. (2006)
23. Plasma chitotriosidase and CCL18: early biochemical surrogate markers in type B Niemann-Pick disease. (PubMed id 15702402)^{1, 9} Brinkman J....Aerts J.M. (2005)
24. Pulmonary and activation-regulated chemokine stimulates collagen production in lung fibroblasts. (PubMed id 12805086)^{1, 9} Atamas S.P....White B. (2003)
25. Expression of the chemokine PARC mRNA in bronchoalveolar cells of patients with sarcoidosis. (PubMed id 12161279)^{1, 9} Mrazek F....Petrek M. (2002)
26. Protein microarray analysis in patients with asthma: elevation of the chemokine PARC/CCL18 in sputum. (PubMed id 19017877)^{1, 9} Kim H.B....Kita H. (2009)
27. CC-chemokine ligand 18/pulmonary activation-regulated chemokine expression in the CNS with special reference to traumatic brain inju ries and neoplastic disorders. (PubMed id 19958819)^{1, 9} Chang C.Y....Wu C.H. (2010)
28. Upregulation of CC chemokine ligand 18 and downregulation of CX3C chemokine receptor 1 expression in human T-cell leukemia virus type 1-associated lymph node lesions: Results of chemokine and chemokine receptor DNA chip analysis. (PubMed id 17900259)^{1, 9} Shimizu K....Ohshima K. (2007)
29. Genetic variation in the CCL18-CCL3-CCL4 chemokine gene cluster influences HIV Type 1 transmission and AIDS disease progression. (PubMed id 16773571)^{1, 9} Modi W.S....Winkler C. (2006)
30. CCL18 production is decreased in alveolar macrophages from cigarette smokers. (PubMed id 19357939)^{1, 9} Kollert F....Prasse A. (2009)
31. Early cutaneous gene transcription changes in adult atopic dermatitis and potential clinical implications. (PubMed id 17181634)^{1, 9} Plager D.A....Pittelkow M.R. (2007)
32. A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18. (PubMed id 16415274)^{1, 9} Prasse A....Zissel G. (2006)
33. CC-chemokine ligand 18 induces epithelial to mesenchym al transition in lung cancer A549 cells and elevates the invasive potential. (PubMed id 23349697)¹ Ploenes T....Zissel G. (2013)
34. CCL18 as an independent favorable prognostic biomarker in patients with colorectal cancer. (PubMed id 23433718)¹ Yuan R....Lan P. (2013)
35. Segmental allergen challenge enhances chitinase activi ty and levels of CCL18 in mild atopic asthma. (PubMed id 23331560)¹ Gavala M.L....Jarjour N.N. (2013)
36. Increased CCL18 expression in patients with cutaneous T-cell lymphoma: association with disease severity and prognosis. (PubMed id 22404649)¹ Miyagaki T....Sato S. (2013)
37. Gene expression profiles in paired gingival biopsies f rom periodontitis-affected and healthy tissues revealed by massively parallel se quencing. (PubMed id 23029519)¹ Davanian H....Yucel-Lindberg T. (2012)
38. CCL18 in a multiplex urine-based assay for the detecti on of bladder cancer. (PubMed id 22629457)¹ Urquidi V....Goodison S. (2012)
39. Enhanced production of CCL18 by tolerogenic dendritic cells is associated with inhibition of allergic airway reactivity. (PubMed id 23102918)¹ Bellinghausen I....Saloga J. (2012)
40. Serum level of CC-chemokine ligand 18 is increased in patients with non-small-cell lung cancer and correlates with survival time in ad enocarcinomas. (PubMed id 22848587)¹ Plones T....Zissel G. (2012)
41. The chemokine CCL18 causes maturation of cultured mono cytes to macrophages in the M2 spectrum. (PubMed id 22117697)¹ Schraufstatter I.U....Discipio R.G. (2012)
42. Increased expression of CC chemokine ligand 18 in pati ents with chronic rhinosinusitis with nasal polyps. (PubMed id 21943944)¹ Peterson S....Kato A. (2012)
43. Chemokines CCL3/MIP1a, CCL5/RANTES and CCL18/PARC are independent risk predictors of short-term mortality in patients with acute coron ary syndromes. (PubMed id 23029252)¹ de Jager S.C....Biessen E.A. (2012)
44. CCL18 -- potential biomarker of fibroinflammatory acti vity in chronic periaortitis. (PubMed id 22589264)¹ Kollert F....Warnatz K. (2012)
45. Pulmonary CCL18 recruits human regulatory T cells. (PubMed id 22649201)¹ Chenivesse C....Tsicopoulos A. (2012)
46. Expression of CCL18 and interleukin-6 in the plasma of breast cancer patients as compared with benign tumor patients and healthy contr ols. (PubMed id 22203932)¹ Narita D....Anghel A. (2011)
47. Evaluation of proteomics-identified CCL18 and CXCL1 as circulating tumor markers for differential diagnosis between ovarian carcinomas and benign pelvic masses. (PubMed id 21928244)¹ Wang Q....Li L. (2011)
48. CCL18 from tumor-associated macrophages promotes brea st cancer metastasis via PITPNM3. (PubMed id 21481794)¹ Chen J....Song E. (2011)
49. Serum CC chemokine ligand-18 predicts lung disease wor sening in systemic sclerosis. (PubMed id 21778167)¹ Tiev K.P....Dinh-Xuan A.T. (2011)
50. Alternative activation of macrophages in human perito neum: implications for peritoneal fibrosis. (PubMed id 21324976)¹ BellA^n T....Bajo M.A. (2011)
51. CCL2, CCL18 and sIL-4R in renal, meningeal and pulmon ary TB; a 2 year study of patients and contacts. (PubMed id 21251883)¹ Mendez A....Rook G.A. (2011)
52. Exploring CCL18, eczema severity and atopy. (PubMed id 21539615)¹ Hon K.L....Leung T.F. (2011)
53. Chemokine CCL18 predicts intraventricular hemorrhage in very preterm infants. (PubMed id 20608885)¹ Kallankari H....Hallman M. (2010)
54. Cardiovascular determinants and prognostic significan ce of CC Chemokine Ligand-18 (CCL18/PARC) in patients with stable coronary arte ry disease. (PubMed id 20674579)¹ De Sutter J....Van Damme J. (2010)
55. Clinical utility of circulating matrix metalloprotein ase-7 (MMP-7), CC chemokine ligand 18 (CCL18) and CC chemokine ligand 11 (CCL11 ) as markers for diagnosis of epithelial ovarian cancer. (PubMed id 19937162)¹ Zohny S.F. and Fayed S.T. (2010)
56. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)¹ Davila S....Seielstad M. (2010)
57. Attenuation of CXCR4 responses by CCL18 in acute lymp hocytic leukemia B cells. (PubMed id 20568229)¹ Catusse J....Burger M. (2010)
58. Expression of chemokine (C-C motif) ligand 18 in huma n macrophages and atherosclerotic plaques. (PubMed id 19036375)¹ HAogg D.A....Svensson P.A. (2009)
59. Common variation in genes related to innate immunity and risk of adult glioma. (PubMed id 19423540)¹ Rajaraman P....Chanock S.J. (2009)
60. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
61. Human protein factory for converting the transcriptome into an in vitro-expressed proteome. (PubMed id 19054851)² Goshima N.... Nomura N. (2008)
62. CCL18 as an indicator of pulmonary fibrotic activity in idiopathic interstitial pneumonias and systemic sclerosis. (PubMed id 17469163)¹ Prasse A....Muller-Quernheim J. (2007)
63. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)¹ Lamesch P.... Vidal M. (2007)
64. Novel insights in the regulation of CCL18 secretion by monocytes and dendritic cells via cytokines, toll-like receptors and rheumatoid synovial fluid. (PubMed id 16984635)¹ van Lieshout A.W....Radstake T.R. (2006)
65. Involvement of CCL18 in allergic asthma. (PubMed id 16670340)¹ de Nadai P....Tsicopoulos A. (2006)
66. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)¹ Stelzl U.... Wanker E.E. (2005)
67. CCL18 is expressed in atopic dermatitis and mediates skin homing of human memory T cells. (PubMed id 15661937)¹ Gunther C....Carballido J.M. (2005)
68. PARC/CCL18 is a plasma CC chemokine with increased levels in childhood acute lymphoblastic leukemia. (PubMed id 14578205)¹ Struyf S....Laureys G. (2003)
69. The dendritic cell-specific chemokine, dendritic cell-derived CC chemokine 1, enhances protective cell-mediated immunity to murine malaria. (PubMed id 12626578)¹ Bruna-Romero O....Tsuji M. (2003)
70. Unique regulation of CCL18 production by maturing dendritic cells. (PubMed id 12646652)¹ Vulcano M....Sozzani S. (2003)
71. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
72. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)
73. Involvement of CC chemokine ligand 18 (CCL18) in normal and pathological processes. (PubMed id 15784687)⁹ Schutyser E....Van Damme J. (2005)
74. Pseudoexons and regulatory elements in the genomic sequence of the beta-chemokine, alternative macrophage activation-associated CC-chemokine (AMAC)-1. (PubMed id 10671296)⁹ Politz O....Goerdt S. (2000)
75. Complex regulation of pulmonary inflammation and fibrosis by CCL18. (PubMed id 17569779)⁹ Pochetuhen K....Atamas S.P. (2007)
76. Serum pulmonary and activation-regulated chemokine/CCL18 levels in patients with systemic sclerosis: a sensitive indicator of active pulmonary fibrosis. (PubMed id 16142750)⁹ Kodera M....Sato S. (2005)
77. The dendritic cell-specific CC-chemokine DC-CK1 is expressed by germinal center dendritic cells and attracts CD38-negative mantle zone B lymphocytes. (PubMed id 11207283)⁹ Lindhout E....Adema G.J. (2001)
78. Expression and cellular localization of the CC chemokines PARC and ELC in human atherosclerotic plaques. (PubMed id 10027395)⁹ Reape T.J....Groot P.H. (1999)
79. Mycobacterium tuberculosis induces CCL18 expression i n human macrophages. (PubMed id 18959625)⁹ Ferrara G....Condos R. (2008)
80. Mechanism of DNA segregation in prokaryotes: replicon pairing by parC of plasmid R1. (PubMed id 9671715)⁹ Jensen R.B....Gerdes K. (1998)
81. PKCalpha mediates CCL18-stimulated collagen production in pulmonary fibroblasts. (PubMed id 16601239)⁹ Luzina I.G....Atamas S.P. (2006)
82. Clinical evaluation of chemokine and enzymatic biomarkers of Gaucher disease. (PubMed id 16125420)⁹ Deegan P.B....Cox T.M. (2005)
83. Langerhans cells do not express alternative macrophage activation-associated CC chemokine (AMAC)-1. (PubMed id 9851514)⁹ Kodelja V....Goerdt S. (1998)
84. [Evaluation of the chemokine variation in tears of contact lens wearers] (PubMed id 17025230)⁹ Iwasaki Y....Sawa M. (2006)
85. C-C chemokine receptor 3 antagonism by the beta-chemokine macrophage inflammatory protein 4, a property strongly enhanced by an amino-terminal alanine-methionine swap. (PubMed id 10640766)⁹ Nibbs R.J....Graham G.J. (2000)
86. Lactic acid bacteria enhance autophagic ability of mo nonuclear phagocytes by increasing Th1 autophagy-promoting cytokine (IFN-gamma) and nitric oxide (NO) levels and reducing Th2 autophagy-restraining cytokines (IL-4 and IL-13) in response to Mycobacterium tuberculosis antigen. (PubMed id 20381647)⁹ Ghadimi D....Schrezenmeir J. (2010)
87. Influence of measles vaccination on the progression of atopic dermatitis in infants. (PubMed id 17617807)⁹ Hennino A....Horvat B. (2007)
88. Expression of C-C chemokines is associated with portal and periportal inflammation in the liver of patients with chronic hepatitis C. (PubMed id 10744077)⁹ Kusano F....Sato C. (2000)
89. Circulating monocytes from systemic sclerosis patient s with interstitial lung disease show an enhanced profibrotic phenotype. (PubMed id 20404807)⁹ Mathai S.K....Herzog E.L. (2010)
90. Alternatively activated and immunoregulatory monocyte s in human filarial infections. (PubMed id 19456233)⁹ Babu S....Nutman T.B. (2009)
91. A pilot study to explore the usefulness of antibody array in childhood atopic dermatitis. (PubMed id 18507202)⁹ Hon K.L....Leung A.K. (2008)
92. Clinical evaluation of biomarkers in Gaucher disease. (PubMed id 15895712)⁹ Deegan P.B. and Cox T.M. (2005)
93. BLC (CXCL13) is expressed by different dendritic cell subsets in vitro and in vivo. (PubMed id 11465112)⁹ Vissers J.L....Adema G.J. (2001)
94. The divergent promoters mediating transcription of th e par locus of plasmid RP4 are subject to autoregulation. (PubMed id 1508044)⁹ Eberl L....Schwab H. (1992)
95. New topoisomerase essential for chromosome segregation in E. coli. (PubMed id 2170028)⁹ Kato J....Suzuki H. (1990)
96. CC chemokines as potential immunologic markers correl ated with clinical improvement of atopic dermatitis patients by immunotherapy. (PubMed id 19758316)⁹ Kwon Y.S....Lee K.H. (2010)
97. Regulation of pulmonary inflammation and fibrosis through expression of integrins alphaVbeta3 and alphaVbeta5 on pulmonary T lymphocytes. (PubMed id 19404954)⁹ Luzina I.G....Atamas S.P. (2009)
98. Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosis. (PubMed id 19179488)⁹ Prasse A....MA1ller-Quernheim J. (2009)
99. Interplay in the selection of fluoroquinolone resista nce and bacterial fitness. (PubMed id 19662169)⁹ Marcusson L.L....Hughes D. (2009)
100. The anti-inflammatory effect of low-dose radiation therapy involves a diminished CCL20 chemokine expression and granulocyte/endothelial cell adhesion. (PubMed id 18188522)⁹ Rodel F....Beuscher H.U. (2008)
101. Distinct effect of CD40 and TNF-signaling on the chemokine/chemokine receptor expression and function of the human monocyte-derived dendritic cells. (PubMed id 18445342)⁹ Xia Y....Zhang X. (2008)
102. Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis. (PubMed id 17472813)⁹ Guttman-Yassky E....Krueger J.G. (2007)
103. Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2). (PubMed id 16735693)⁹ Sironi M....Mantovani A. (2006)
104. Cytokine profile in synovial fluid from patients with internal derangement of the temporomandibular joint: a preliminary study. (PubMed id 17082335)⁹ Matsumoto K....Otsuka K. (2006)
105. Profiling the cytokines in gingival crevicular fluid using a cytokine antibody array. (PubMed id 16671879)⁹ Sakai A....Ito K. (2006)
106. Infiltration of activated dendritic cells and T cells in renal cell carcinoma following combined cytokine immunotherapy. (PubMed id 16115526)⁹ Verra N....Vyth-Dreese F. (2005)
107. Haplotype structure and linkage disequilibrium in chemokine and chemokine receptor genes. (PubMed id 15588486)⁹ Clark V.J. and Dean M. (2004)
108. Phenotypical and functional characterization of clinical grade dendritic cells. (PubMed id 12218781)⁹ de Vries I.J....Figdor C.G. (2002)
109. Quantitative analysis of chemokine expression by dendritic cell subsets in vitro and in vivo. (PubMed id 11358988)⁹ Vissers J.L....Adema G.J. (2001)
110. Generation of functional human dendritic cells from adherent peripheral blood monocytes by CD40 ligation in the absence of granulocyte-macrophage colony-stimulating factor. (PubMed id 9834229)⁹ Brossart P....Brugger W. (1998)
111. Novel lymphocyte-specific CC chemokines and their receptors. (PubMed id 9365118)⁹ Yoshie O....Nomiyama H. (1997)
112. Activation of human eosinophils and epidermal keratin ocytes by Th2 cytokine IL-31: implication for the immunopathogenesis of atopic dermatitis. (PubMed id 20410259)⁹ Cheung P.F....Lam C.W. (2010)
113. Transferable quinolone resistance in Vibrio cholerae. (PubMed id 19949057)⁹ Kim H.B....Hooper D.C. (2010)
114. Molecular emm genotyping and antibiotic susceptibilit y of Streptococcus dysgalactiae subsp. equisimilis isolated from invasive and n on-invasive infections. (PubMed id 19745030)⁹ Sunaoshi K....Ubukata K. (2010)
115. The effects of inhaled and oral corticosteroids on se rum inflammatory biomarkers in COPD: an exploratory study. (PubMed id 19465442)⁹ Man S.F....Sin D.D. (2009)
116. Corticotropin-releasing factor decreases IL-18 in the monocyte-derived dendritic cell. (PubMed id 18803662)⁹ Lee H.J....Lee K.H. (2009)
117. Remodeling phenotype of human subcutaneous adipose tissue macrophages. (PubMed id 18227385)⁹ Bourlier V....Bouloumie A. (2008)
118. CD30 expression on CD1a+ and CD8+ cells in atopic dermatitis and correlation with disease severity. (PubMed id 18086588)⁹ Oflazoglu E....Gerber H.P. (2008)
119. Plasma glucosylceramide and ceramide in type 1 Gaucher disease patients: correlations with disease severity and response to therapeutic intervention. (PubMed id 18155675)⁹ Groener J.E....Aerts J.M. (2008)
120. [Alternatively activated macrophages/mononuclear phagocytes promote growth and invasion of breast cancer cell line SKBR3] (PubMed id 17545016)⁹ Guo J.J....Chen J.S. (2007)
121. High CCL18/PARC expression in articular cartilage and synovial tissue of patients with rheumatoid arthritis. (PubMed id 17304652)⁹ Momohara S....Tomatsu T. (2007)
122. Modulation of chemokines by staphylococcal superantigen in atopic dermatitis. (PubMed id 17369706)⁹ Homey B....Lauerma A. (2007)
123. Short-term effect of miglustat in every day clinical use in treatment-naive or previously treated patients with type 1 Gaucher's disease. (PubMed id 16627252)⁹ Giraldo P....Pocovi M. (2006)
124. Identification of genes involved in the suppression of antibody production from human peripheral blood lymphocytes. (PubMed id 16636465)⁹ Aiba Y....Shirahata S. (2006)
125. Microarray and protein analysis of human pterygium. (PubMed id 16446702)⁹ John-Aryankalayil M....Carper D.A. (2006)
126. Chemokine networks in atopic dermatitis: traffic signals of disease. (PubMed id 15967069)⁹ Pivarcsi A. and Homey B. (2005)
127. Patterns of protein expression in infectious meningitis: a cerebrospinal fluid protein array analysis. (PubMed id 15885808)⁹ Kastenbauer S....Koedel U. (2005)
128. Chemokines and gelatinases in the aqueous humor of patients with active uveitis. (PubMed id 15364222)⁹ Abu El-Asrar A.M....Geboes K. (2004)
129. The inflammatory side of human chondrocytes unveiled by antibody microarrays. (PubMed id 15381094)⁹ De Ceuninck F....Anract P. (2004)
130. Transcriptional analysis of human peripheral blood mononuclear cells after influenza immunization. (PubMed id 15364265)⁹ Diaz-Mitoma F....Giulivi A. (2004)
131. Emergence of levofloxacin-resistant pneumococci in im munocompromised adults after therapy for community-acquired pneumonia. (PubMed id 12884162)⁹ Anderson K.B....Low D.E. (2003)
132. Cefotaxime acts synergistically with levofloxacin in experimental meningitis due to penicillin-resistant pneumococci and prevents selection of levofloxacin-resistant mutants in vitro. (PubMed id 12878509)⁹ Kuhn F....Cottagnoud P. (2003)
133. Serum of patients with Behcet's disease induces classical (pro-inflammatory) activation of human macrophages in vitro. (PubMed id 12673080)⁹ Alpsoy E....Zouboulis C.h.C. (2003)
134. High expression of chemokines Gro-alpha (CXCL-1), IL-8 (CXCL-8), and MCP-1 (CCL-2) in inflamed human corneas in vivo. (PubMed id 12796254)⁹ Spandau U.H....Kruse F.E. (2003)
135. Cytokine regulation of pulmonary fibrosis in scleroderma. (PubMed id 14563355)⁹ Atamas S.P. and White B. (2003)
136. Use of cDNA arrays to generate differential expression profiles for inflammatory genes in human gestational membranes delivered at term and preterm. (PubMed id 11912289)⁹ Marvin K.W....Mitchell M.D. (2002)
137. Blockade of B7/CD28 in mixed lymphocyte reaction cultures results in the generation of alternatively activated macrophages, which suppress T-cell responses. (PubMed id 11830501)⁹ Tzachanis D....Boussiotis V.A. (2002)
138. Expression of lymphocyte-specific chemokines in human malignant glioma: Essential role of LARC in cellular immunity of malignant glioma. (PubMed id 12239608)⁹ Kimura T....Ushio Y. (2002)

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