Aliases for CCL17 Gene
External Ids for CCL17 Gene
Previous HGNC Symbols for CCL17 Gene
Previous GeneCards Identifiers for CCL17 Gene
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014]
GeneCards Summary for CCL17 Gene
CCL17 (Chemokine (C-C Motif) Ligand 17) is a Protein Coding gene. Diseases associated with CCL17 include mycosis fungoides and paragonimiasis. Among its related pathways are Signaling by GPCR and TGF-Beta Pathway. GO annotations related to this gene include receptor binding and chemokine activity.
UniProtKB/Swiss-Prot for CCL17 Gene
Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.