Aliases for CCL15 Gene
External Ids for CCL15 Gene
Previous HGNC Symbols for CCL15 Gene
Previous GeneCards Identifiers for CCL15 Gene
This gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C-C chemokine receptor type 1 (CCR1). The proprotein is further processed into numerous smaller functional peptides. Naturally-occurring readthrough transcripts occur from this gene into the downstream gene, CCL14 (chemokine (C-C motif) ligand 14). [provided by RefSeq, Jan 2013]
GeneCards Summary for CCL15 Gene
CCL15 (Chemokine (C-C Motif) Ligand 15) is a Protein Coding gene. Among its related pathways are TGF-Beta Pathway and Akt Signaling. GO annotations related to this gene include receptor binding and chemokine activity.
UniProtKB/Swiss-Prot for CCL15 Gene
Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15.