CCL13 Gene
protein-coding GIFtS: 64
GCID: GC17P032684
|
|
chemokine (C-C motif) ligand 13(Previous names: small inducible cytokine subfamily A (Cys-Cys), member...)
(Previous symbol: SCYA13)
| |
Aliases
for CCL13 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chemokine (C-C Motif) Ligand 131 2 | | Monocyte Chemoattractant Protein 42 3 | | SCYA131 2 3 5 | | Monocyte Chemotactic Protein 42 3 | | MCP-41 2 3 | | Small-Inducible Cytokine A132 3 | | NCC-11 2 3 | | CK-Beta-101 | | NCC12 3 5 | | MGC171341 | | CKb101 2 | | C-C Motif Chemokine 132 | | SCYL11 2 | | New CC Chemokine 12 | | Small Inducible Cytokine Subfamily A (Cys-Cys), Member 131 2 | | MCP43 |
Export aliases for CCL13 gene to outside databasesPrevious GC identifers: GC17P032453 GC17P034723 GC17P032829 GC17P029707 GC17P028869 |
Summaries
for CCL13 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CCL13:
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a familyof secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteinscharacterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity formonocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation ofleukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall duringartherosclerosis. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CCL13_HUMAN, Q99616Function: Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils.Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic andnon-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the diseaseprocess of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenouspathogens
|
Genomic Views
for CCL13 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010799.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCL13 gene promoter:
E2F-3a E2F-4 E2F-5 AML1a E2F-2 Meis-1b E2F-1 E2F Meis-1a Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCL13
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCL13 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q11.2 Ensembl cytogenetic band: 17q12 HGNC cytogenetic band: 17q11.2CCL13 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P032684: view genomic region
(about GC identifiers)
Start:
|
32,683,471 bp from pter |
End:
|
32,685,629 bp from pter |
Size:
|
2,159 bases |
Orientation:
|
plus strand |
|
Proteins
for CCL13 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CCL13_HUMAN, Q99616 (See
protein sequence)Recommended Name: C-C motif chemokine 13 precursor Size: 98 amino acids; 10986 Da
Subcellular location: Secreted
Mass spectrometry: Mass=9314; Mass_error=30; Method=MALDI; Range=17-98; Source=PubMed:8642349;
Mass spectrometry: Mass=8760; Mass_error=30; Method=MALDI; Range=22-98; Source=PubMed:8642349;
Mass spectrometry: Mass=8575; Mass_error=30; Method=MALDI; Range=24-98; Source=PubMed:8642349;
Miscellaneous: This protein can bind heparin
1 PDB 3D structure from  and Proteopedia  for CCL13:2RA4 (3D)
Secondary accessions: O95689 Q6ICQ6Explore the universe of human proteins at neXtProt for CCL13: NX_Q99616
Post-translational modifications:
One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signalpeptide cleavage. The medium chain is about 30-fold less active than the long chain1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q99616
CCL13 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_005399.1
ENSEMBL proteins: ENSP00000225844 ENSP00000463667
Human Recombinant Protein Products for CCL13:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005615 | extracellular space |
IEA | -- |
CCL13 for ontologies About GeneDecksing
CCL13 Antibody Products:
Assay Products for CCL13: |
Protein
Domains /
Families
for CCL13 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CCL13 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q99616ProtoNet protein and cluster: Q99616 1 Blocks protein family: IPB000827 Small chemokine
UniProtKB/Swiss-Prot: CCL13_HUMAN, Q99616Similarity: Belongs to the intercrine beta (chemokine CC) family |
Function
for CCL13 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: CCL13_HUMAN, Q99616Function: Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils.Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic andnon-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the diseaseprocess of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenouspathogensInduction: By IL1/interleukin-1 and TNF Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
CCL13 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for CCL13:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCL13
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCL13 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CCL13 (NM_005408) | |  | Sino Biological Human cDNA Clone for CCL13 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCL13 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCL13 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCL13 |
|
Pathways & Interactions
for CCL13 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | PEDF Induced Signaling | | | 2 | TGF-Beta Pathway | | | 3 | Akt Signaling | | | 4 | Rho Family GTPases | | | 5 | Immune response _CCR3 signaling in eosinophils | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for CCL13
5/28 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CCL13 (see all 28)
1  GeneGo (Thomson Reuters) Pathway for CCL13
2 
Kegg Pathways (Kegg details for CCL13):
CCL13 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CCL13
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
5/25 Interacting proteins for CCL13 (Q996162, 3 ENSP000002258444) via UniProtKB, MINT, STRING, and/or I2D (see all 25)About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
CCL13 for ontologies About GeneDecksing
|
Drugs & Compounds
for CCL13 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CCL13 for compounds About GeneDecksing
 Browse Tocris compounds for CCL13
7 Novoseek chemical compound relationships for CCL13 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| rantes |
90.5 |
86 |
10570327 (4), 10725746 (4), 9276730 (4), 10553092 (3) (see all 49) |
| tarc |
76.1 |
6 |
10419874 (1), 19236470 (1), 9430724 (1), 15644118 (1) (see all 5) |
| histamine |
31.9 |
2 |
8955214 (1), 9276730 (1) |
| calcium |
26.6 |
17 |
10069890 (2), 8955214 (1), 9365122 (1), 10072545 (1) (see all 11) |
| dexamethasone |
0.655 |
1 |
11597922 (1) |
| oxygen |
0 |
3 |
9367876 (1), 9551887 (1), 11286614 (1) |
| steroid |
0 |
3 |
15523430 (2) |
Search CenterWatch for drugs/clinical trials and news about CCL13
|
Transcripts
for CCL13 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCL13 gene: NM_005408.2 Unigene Cluster for CCL13: Chemokine (C-C motif) ligand 13 Hs.414629 [show with all ESTs]Unigene Representative Sequence: NM_0054082 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000225844(uc002hic.3) ENST00000577681
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCL13
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCL13 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CCL13 (NM_005408) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCL13 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCL13 |
Additional cDNA sequence: AJ001634.1 BC008621.1 BT007385.1 CR450337.1 U46767.1 U59808.1 X98306.1 Z77650.1 Z77651.1 1 DOTS entry: DT.110724 24/28 AceView cDNA sequences (see all 28): BC008621 CR450337 CK902425 U59808 BX119227 AA403048 BU071409 NM_005408 Z77651 AJ001634 BM991948 AW204819 BG620880 AI459919 U46767 AW015321 AA760939 AA404346 AA426245 BF339001 Z77650 BT007385 BU071645 AI925360
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for CCL13 About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 |
|---|
|
| SP1: | | | | | | | | | | | |
| SP2: | | | | | | | - | | | |
ECgene alternative splicing isoforms for CCL13
|
Expression
for CCL13 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCL13 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGGGATGCT
About this image
See CCL13 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCL13
SOURCE GeneReport for Unigene cluster: Hs.414629
UniProtKB/Swiss-Prot: CCL13_HUMAN, Q99616Tissue specificity: Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node.Low levels seen in the pulmonary artery smooth muscle cells
SABiosciences Expression via Pathway-Focused PCR Arrays including CCL13 (see all 17): | Cancer PathwayFinder in human mouse rat | | Inflammasomes in human mouse rat | | Th17 Response in human mouse rat | | Endothelial Cell Biology in human mouse rat | | NFKB Signaling Pathway in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCL13
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CCL13 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCL13 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCL13 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCL13 |
Orthologs
for CCL13 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CCL13 gene from 1/7 species (see all 7) About this table
ENSEMBL Gene Tree for CCL13 (if available)
TreeFam Gene Tree for CCL13 (if available) |
Paralogs
for CCL13 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CCL13 gene
- CCL152 CCL162 CCL22 CCL142 CCL242 CCL4L12 CCL112 CCL72
- CCL4L22 CCL3L12 CCL52 CCL232 CCL3L32 CCL42 CCL82 CCL262
- CCL32 CCL182
18/28 SIMAP similar genes for CCL13 using alignment to 3 protein entries: CCL13_HUMAN (see all proteins)
(see all similar genes):CCL2 CCL11 CCL7 MCP-3 CCL8 XCL1
XCL2 CCL3L1 CCL3L3 CCL3 CCL4 CCL4L2
LOC728835 CCL4L1 CCL18 CCL14 CCL5 CCL1
CCL13 for paralogs About GeneDecksing
|
Genomic Variants
for CCL13 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCL13 (32683471 - 32685629 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CCL13
1 CNV: 49841
Human Gene Mutation Database (HGMD): CCL13
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCL13 |
|
Disorders
/ Diseases
for CCL13 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CCL13 for disorders About GeneDecksing
OMIM gene information: 601391
OMIM disorders: --
20/32  diseases for CCL13 (see all 32): About MalaCardsfar eastern spotted fever human immunodeficiency virus infectious disease allergic rhinitis bullous pemphigoid
amyotrophic lateral sclerosis lateral sclerosis atopic dermatitis rhinitis
eosinophilia dermatitis bronchiolitis nephrotic syndrome
rheumatoid arthritis asthma multiple sclerosis atopy
tonsillitis gastric adenocarcinoma hepatitis b encephalomyelitis
4 diseases from the University of Copenhagen DISEASES database for CCL13:Asthma Atopic dermatitis Eosinophilia Far Eastern spotted fever 10/14 Novoseek disease relationships for CCL13 gene (see all 14) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| inflammation |
54.5 |
21 |
11400154 (2), 8955214 (1), 10808183 (1), 11391951 (1) (see all 15) |
| asthma |
48.5 |
34 |
15046375 (8), 10934112 (4), 10069883 (3), 12805085 (1) (see all 5) |
| eosinophilia |
41.1 |
2 |
10415058 (1), 10491000 (1) |
| nasal polyps |
38.4 |
6 |
15523430 (2), 17851891 (2), 10415058 (1) |
| allergic reaction |
35.5 |
2 |
10934112 (1), 10491000 (1) |
| necrosis |
30.8 |
8 |
10934112 (1), 9060459 (1), 20139115 (1), 19643942 (1) (see all 7) |
| allergy |
29.5 |
3 |
9800627 (1), 10875484 (1), 10640766 (1) |
| allergic rhinitis |
23.5 |
2 |
10359883 (1), 17982926 (1) |
| asthma allergic |
18.4 |
2 |
10934112 (1) |
| dermatitis atopic |
4.84 |
1 |
10808183 (1) |
Human Genome Epidemiology (HuGE) Navigator: CCL13 (13 documents)
Export disorders for CCL13 gene to outside databases
|
Publications
for CCL13 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCL13 gene, integrated from 9 sources (see all 139):
(articles sorted by number of sources associating them with CCL13) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin. (PubMed id 8642349)1, 2, 9 Uguccioni M.... Baggiolini M. (1996)
- Cloning, in vitro expression, and functional characterization of a novel human CC chemokine of the monocyte chemotactic protein (MCP) family (MCP-4) that binds and signals through the CC chemokine receptor 2B. (PubMed id 9195948)1, 2, 9 Berkhout T.A.... Macphee C. (1997)
- Monocyte chemotactic protein-4: tissue-specific expression and signaling through CC chemokine receptor-2. (PubMed id 9060459)1, 2, 9 Godiska R....Gray P.W. (1997)
- Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3. (PubMed id 8955214)1, 2, 9 Garcia-Zepeda E.A.... Luster A.D. (1996)
- Genomic organization, sequence analysis and transcriptional regulation of the human MCP-4 chemokine gene (SCYA13) in dermal fibroblasts: a comparison to other eosinophilic beta-chemokines. (PubMed id 10049733)1, 2, 9 Hein H....Bartels J. (1999)
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)1, 2 Zody M.C.... Nusbaum C. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A YAC contig of the human CC chemokine genes clustered on chromosome 17q11.2. (PubMed id 8661057)1, 3 Naruse K....Miura R. (1996)
- Monocyte chemoattractant protein-4 core promoter genetic variants: influence on YY-1 affinity and plasma levels. (PubMed id 12805085)1, 9 Kalayci O....Lilly C.M. (2003)
- Induction of CCL13 expression in synovial fibroblasts highlights a significant role of oncostatin M in rheumatoid arthritis. (PubMed id 19565514)1, 9 Hintzen C....Hermanns H.M. (2009)
|
External Searches for CCL13 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCL13 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCL13 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCL13 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCL13 | Pharmacogenomics, SNPs, Pathways | | Wikipedia | http://en.wikipedia.org/wiki/CCL13 |
|
| | |
About This Section
| Patent Information for CCL13 gene:
Search GeneIP for patents involving CCL13
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCL13 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CCL13 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCL13 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCL13 | | | OriGene Protein Over-expression Lysate for CCL13 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCL13 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCL13 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCL13 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCL13 | | OriGene Custom Protein Services for CCL13 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCL13 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCL13 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCL13 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCL13 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCL13 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCL13 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for CCL13 |
| |  |  |  |  | | | | | | Recombinant Protein for CCL13 |
|
 |
 |
 |
 | | | CCL13 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCL13 |
|  |  |  |  | | | | ThermoFisher Antibodies for CCL13 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCL13 |
| |  | |
|
|
|
