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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CCHCR1 Gene

protein-coding   GIFtS: 55
GCID: GC06M031110

coiled-coil alpha-helical rod protein 1

(Previous name: chromosome 6 open reading frame 18 )
(Previous symbol: C6orf18)
 Explore 10 diseases affiliated with
CCHCR1 via
MalaCards
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 Human Malady Compendium 
Biological research products
for CCHCR1    

Aliases
for CCHCR1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Coiled-Coil Alpha-Helical Rod Protein 11 2     SBP2
HCR1 2 3 5     HCR (A-Helix Coiled-Coil Rod Homologue)2
C6orf181 2 3     Pg83
Alpha-Helical Coiled-Coil Rod Protein2 3     StAR-Binding Protein2
Putative Gene 8 Protein2 3     Pg83
Chromosome 6 Open Reading Frame 181     C6ORF185

External Ids:    HGNC: 139301   Entrez Gene: 545352   Ensembl: ENSG000002045367   OMIM: 6053105   UniProtKB: Q8TD313   

Export aliases for CCHCR1 gene to outside databases

Previous GC identifers: GC06M031219 GC06M030912


Summaries
for CCHCR1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: CCHCR_HUMAN, Q8TD31
Function: May be a regulator of keratinocyte proliferation or differentiation

Gene Wiki entry for CCHCR1


Genomic Views
for CCHCR1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  NT_113891.2  NT_167245.1  NT_167246.1  NT_167247.1  NT_167248.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CCHCR1 gene promoter:
         AP-1   ATF-2   STAT3   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CCHCR1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CCHCR1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCHCR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p21.33   HGNC cytogenetic band: 6p21.3

CCHCR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCHCR1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M031110:  view genomic region     (about GC identifiers)

Start:
 31,110,216 bp from pter      End:
 31,126,015 bp from pter
Size:
 15,800 bases      Orientation:
 minus strand

5 alternative locations:
Chr6-,ALT_REF_LOCI_3 31,103,949-31,130,784      Chr6-,ALT_REF_LOCI_2 31,102,772-31,157,756      Chr6-,ALT_REF_LOCI_5 31,103,575-31,119,395     
Chr6-,ALT_REF_LOCI_4 31,078,233-31,094,052      Chr6-,ALT_REF_LOCI_6 31,102,653-31,154,050     

Proteins
for CCHCR1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CCHCR_HUMAN, Q8TD31 (See protein sequence)
Recommended Name: Coiled-coil alpha-helical rod protein 1  
Size: 782 amino acids; 88671 Da
Subcellular location: Cytoplasm. Nucleus
Sequence caution: Sequence=AAF74221.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAA81890.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAA82158.1;
Type=Erroneous gene model prediction; Sequence=BAA91236.1; Type=Erroneous initiation; Note=Translation N-terminally
extended; Sequence=BAB63313.1; Type=Erroneous gene model prediction; Sequence=BAC54937.1; Type=Erroneous gene model
prediction;
Secondary accessions: A2ABH6 Q2TB67 Q5SQ82 Q5STE9 Q9NRK8 Q9NWY9 Q9NXJ4 Q9NXK3 Q9Y6W1 Q9Y6W2
Alternative splicing: 2 isoforms:  Q8TD31-1   Q8TD31-2   (Ref.6 (AAI10536) sequence differs from that shown due to erroneous termination (Translated as Trp in position 78))

Explore the universe of human proteins at neXtProt for CCHCR1: NX_Q8TD31

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8TD31

    • CCHCR1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001099033.1  NP_001099034.1  NP_061925.2  

    ENSEMBL proteins: 
     ENSP00000379566   ENSP00000365442   ENSP00000379561   ENSP00000397125   ENSP00000401039  
     ENSP00000426883   ENSP00000422844   ENSP00000422503   ENSP00000421523   ENSP00000414323  
     ENSP00000421393   ENSP00000390027   ENSP00000425682   ENSP00000421992   ENSP00000422975  
     ENSP00000420941   ENSP00000398715   ENSP00000413000   ENSP00000425595   ENSP00000402432  
     ENSP00000425377   ENSP00000420911   ENSP00000389303   ENSP00000424335   ENSP00000422000  
     ENSP00000424164   ENSP00000425435  

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    Uscn Proteins for CCHCR1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--
    GO:0043231intracellular membrane-bounded organelle IDA--


    CCHCR1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for CCHCR1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CCHCR1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR009800 HCR

    Graphical View of Domain Structure for InterPro Entry Q8TD31

    ProtoNet protein and cluster: Q8TD31

    1 Blocks protein family: IPB009800 Alpha helical coiled-coil rod


    Function
    for CCHCR1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CCHCR_HUMAN, Q8TD31
    Function: May be a regulator of keratinocyte proliferation or differentiation

    miRNA
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    Gene Editing
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    In Situ Assay
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----


    CCHCR1 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for CCHCR1:
     Increased gamma-H2AX phosphory  Synthetic lethal with Ras 


    Pathways & Interactions
    for CCHCR1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CCHCR1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/9 Interacting proteins for CCHCR1 (Q8TD312, 3 ENSP000003795664) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRKCGP051292, 3, ENSP000002634314MINT-2873755 I2D: score=3 STRING: ENSP00000263431
    POLR2CP193873, ENSP000002192524I2D: score=3 STRING: ENSP00000219252
    STARP496753, ENSP000002764494I2D: score=2 STRING: ENSP00000276449
    TRAF4Q9BUZ43, ENSP000002623954I2D: score=3 STRING: ENSP00000262395
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006611protein export from nucleus IEA--
    GO:0007275multicellular organismal development IEA--
    GO:0030154cell differentiation IEA--


    CCHCR1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CCHCR1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CCHCR1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CCHCR1
    2 Novoseek chemical compound relationships for CCHCR1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    steroid 21.5 3 17221218 (2)
    cholesterol 11.1 1 17221218 (1)

    1 PharmGKB related drug/compound annotation for CCHCR1 gene
    Drug/compound PharmGKB Annotation
    allopurinolCA  
    About this table

    Search CenterWatch for drugs/clinical trials and news about CCHCR1 / CCHCR 

    Transcripts
    for CCHCR1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CCHCR1 gene (3 alternative transcripts): 
    NM_001105563.1  NM_001105564.1  NM_019052.3  

    Unigene Cluster for CCHCR1:

    Coiled-coil alpha-helical rod protein 1
    Hs.485075  [show with all ESTs]
    Unigene Representative Sequence: NM_001105564
    18/35 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 35):
    ENST00000396268(uc003nsq.4 uc003nsp.4) ENST00000376266(uc003nsr.4)
    ENST00000396263 ENST00000440185(uc011dne.2) ENST00000451521 ENST00000467553
    ENST00000486060 ENST00000509859 ENST00000509552(uc010jsk.1) ENST00000480060
    ENST00000512418 ENST00000502672 ENST00000508852 ENST00000507459 ENST00000464012
    ENST00000505392 ENST00000448141 ENST00000508683

    miRNA
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    Inhib. RNA
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AB029331.1 AB112474.1 AB112475.1 AF216493.1 AK000204.1 AK000217.1 AK000533.1 AK289446.1 
    AK295494.1 AK310626.1 AY029160.1 BC110534.1 BC110535.1 CR457227.1 

    18 DOTS entries:

    DT.411976  DT.100648749  DT.91752756  DT.121337487  DT.91752761  DT.95356762  DT.100748104  DT.121337480 
    DT.91752755  DT.100815372  DT.100766123  DT.121337491  DT.121337509  DT.411974  DT.75102096  DT.91737395 
    DT.95093399  DT.95278560 

    20 AceView cDNA sequences:

    BX094003 AB112475 BV178608 AK000217 AB112474 AW365870 NM_019052 BX386673 
    AW375340 CR457227 BX372240 AF216493 BX444927 AK000533 AY029160 AB029331 
    AK000204 BX435108 AW009022 BF901504 

    GeneLoc Exon Structure


    Expression
    for CCHCR1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CCHCR1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTGGCCACCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See CCHCR1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CCHCR1

    SOURCE GeneReport for Unigene cluster: Hs.485075

    UniProtKB/Swiss-Prot: CCHCR_HUMAN, Q8TD31
    Tissue specificity: Found in all tissues tested, abundantly expressed in heart, liver, skeletal muscle, kidney and
    pancreas, and to a lesser extent in lung and placenta. Overexpressed in keratinocytes of psoriatic lesions

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    In Situ
    Assay Products:     
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    Orthologs
    for CCHCR1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for CCHCR1 gene from 3/11 species (see all 11)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Cchcr11 , 5 coiled-coil alpha-helical rod protein 11, 5 80.68(n)1
    75.36(a)1    		   17 (18.69 cM)5
    2400841  NM_146248.21  NP_666360.21 
     355171005 
    lizard
    (Anolis carolinensis)    		 Reptilia CCHCR16
    		 --
    		 38(a)
    		 1 ↔ 1
    		 GL343623.1(264676-282718)
    zebrafish
    (Danio rerio)    		 Actinopterygii si:dkeyp-20g2.31 si:dkeyp-20g2.3 44.39(n)
    32.51(a)    		   567236  XM_690528.4  XP_695620.2 


    ENSEMBL Gene Tree for CCHCR1 (if available)
    TreeFam Gene Tree for CCHCR1 (if available) 

    Paralogs
    for CCHCR1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for CCHCR1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: CCHCR_HUMAN, Q8TD31
    Polymorphism: HCR*WWCC is associated with susceptibility to psoriasis. Psoriasis is a chronic inflammatory dermatosis
    that affects approximately 2% of the population. It is a multifactorial disease characterized by red, scaly skin
    lesions that are usually found on the scalp, elbows, and knees, and may be associated with severe arthritis. The
    lesions are caused by hyperproliferative keratinocytes and infiltration of inflammatory cells into the dermis and
    epidermis. The usual age of onset of psoriasis is between 15 and 30 years, although it can present at any age.
    Association of HCR with psoriasis seem to be due to linkage disequilibrium with Cw*06:02 (PubMed:11348465). HCR is
    unlikely to be directly involved in psoriasis development


    10/391 NCBI SNPs in CCHCR1 are shown (see all 391)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1420564111,2
    		--31109739(+) CCCACC/TTCAGG 3 -- int10--------
    rs92637381,2
    		C,F,H,--31109767(+) TCCCCT/CGCTCA 3 -- int110Minor allele frequency- C:0.14NS EA WA NA CSA 784
    rs666378291,2
    		C,--31109799(+) TTTCTATC/-ATATC 3 -- int11Minor allele frequency- -:0.50CSA 2
    rs12650871,2
    		C,F,A,H,--31109810(-) CAGTAA/C/G/T 
                GATGA     		3 -- int128MN NS EA NA CSA WA 3124
    rs1876141331,2
    		--31109846(+) AAACGA/CTCTCG 3 -- int10--------
    rs1431573581,2
    		--31109851(+) ATCTCA/GTTCAT 3 -- int10--------
    rs12650861,2
    		C,F,A,H,--31109882(-) GAGAGC/AGAGCG 3 -- int125Minor allele frequency- A:0.49NS EA MN NA WA CSA 2529
    rs1482414461,2
    		--31109909(+) TCTCAA/GGGTCC 3 -- int10--------
    rs1918917621,2
    		--31109941(+) AGTGCC/TTAGCT 3 -- int10--------
    rs31325401,2
    		C,F,A,H,--31109943(-) AGAGCC/TAGGCA 3 -- int112Minor allele frequency- T:0.17EA NS NA WA CSA 548

    HapMap Linkage Disequilibrium report for CCHCR1 (31110216 - 31126015 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for CCHCR1
         2 CNVs: 3601 7560
    Human Gene Mutation Database (HGMD): CCHCR1

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCHCR1
    DNA2.0 Custom Variant and Variant Library Synthesis for CCHCR1

    Disorders / Diseases
    for CCHCR1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CCHCR1 for disorders           About GeneDecksing

    OMIM gene information: 605310    OMIM disorders: --

    10 diseases for CCHCR1:    About MalaCards
    systemic lupus erythematosus    lupus erythematosus    psoriatic arthritis    ulcerative colitis
    psoriasis    skin cancer    arthritis    ataxia
    cholesterol    sepsis

    1 disease from the University of Copenhagen DISEASES database for CCHCR1:
    Psoriasis

    1 Novoseek disease relationship for CCHCR1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    psoriasis 68.4 24 17221218 (5), 11348465 (4), 10888604 (3), 11875053 (2) (see all 6)

    Genetic Association Database (GAD): CCHCR1
    Human Genome Epidemiology (HuGE) Navigator: CCHCR1 (12 documents)

    Export disorders for CCHCR1 gene to outside databases

    Publications
    for CCHCR1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CCHCR1 gene, integrated from 9 sources (see all 40):
    (articles sorted by number of sources associating them with CCHCR1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A candidate gene for psoriasis near HLA-C, HCR (Pg8), is highly polymorphic with a disease-associated susceptibility allele. (PubMed id 10888604)1, 2, 3, 9 Asumalahti K.... Kere J. (2000)
    2. Association analysis using refined microsatellite markers localizes a susceptibility locus for psoriasis vulgaris within a 111 kb segment telomeric to the HLA-C gene. (PubMed id 10545595)1, 2, 3 Oka A....Inoko H. (1999)
    3. The HCR gene on 6p21 is unlikely to be a psoriasis susceptibility gene. (PubMed id 11348465)1, 2, 9 O'Brien K.P.... Staahle-Baeckdahl M. (2001)
    4. Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus. (PubMed id 11875053)1, 2, 9 Asumalahti K.... Kere J. (2002)
    5. The major psoriasis susceptibility locus PSORS1 is not a risk factor for late-onset psoriasis. (PubMed id 15654960)1, 4 Allen M.H....Barker J.N. (2005)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. HCR, a candidate gene for psoriasis, is expressed differently in psoriasis and other hyperproliferative skin disorders and is downregulated by interferon-gamma in keratinocytes. (PubMed id 14675183)1, 2 Suomela S.... Saarialho-Kere U. (2003)
    8. The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes. (PubMed id 17221218)1, 9 Tiala I....Elomaa O. (2007)
    9. Steroidogenic acute regulatory protein-binding protein cloned by a yeast two-hybrid system. (PubMed id 12909641)1, 9 Sugawara T....Fujimoto S. (2003)
    10. A whole-genome association study of major determinants for allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients. (PubMed id 21912425)1 Tohkin M....Ikezawa Z. (2013)

    External Searches for CCHCR1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    Genome Databases showing CCHCR1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54535 HGNC: 13930 AceView: C6orf18 Ensembl:ENSG00000204536 euGenes: HUgn54535
    ECgene: CCHCR1 H-InvDB: CCHCR1

    Other Databases showing CCHCR1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CCHCR1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CCHCR1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CCHCR1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CCHCR1 gene:
    Search GeneIP for patents involving CCHCR1

    GeneCards and IP:
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