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Aliases for CCDC97 Gene

Aliases for CCDC97 Gene

  • Coiled-Coil Domain Containing 97 2 3 5

External Ids for CCDC97 Gene

Previous GeneCards Identifiers for CCDC97 Gene

  • GC19P046508
  • GC19P041816
  • GC19P038249

Summaries for CCDC97 Gene

GeneCards Summary for CCDC97 Gene

CCDC97 (Coiled-Coil Domain Containing 97) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC97 Gene

Genomics for CCDC97 Gene

Regulatory Elements for CCDC97 Gene

Enhancers for CCDC97 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G040713 2.1 FANTOM5 Ensembl ENCODE dbSUPER 38.1 -591.8 -591842 9.2 CREB3L1 DMAP1 FEZF1 YY1 ZNF143 ZNF416 ZNF548 SP3 NFYC SSRP1 SNRPA FBL ITPKC ENSG00000205041 ENSG00000269843 CCDC97 PSMC4 NUMBL COQ8B ENSG00000269069
GH19G040747 1.8 FANTOM5 ENCODE dbSUPER 29.3 -557.4 -557428 9.8 MLX CREB3L1 ZFP64 DMAP1 YBX1 FEZF1 YY1 ZNF416 ZNF143 ZNF263 ENSG00000269843 SNRPA ENSG00000205041 FBL COQ8B ITPKC CCDC97 NUMBL C19orf54 SERTAD3
GH19G041348 1.5 ENCODE dbSUPER 33.9 +41.4 41425 6.9 CREB3L1 AGO1 ZFP64 YBX1 DMAP1 FEZF1 YY1 ZNF143 ZNF263 SP3 ZNF526 ZNF574 SNRPA CCDC97 ITPKC ENSG00000269843 NUMBL MEGF8 TMEM91 SERTAD3
GH19G040830 1.6 Ensembl ENCODE dbSUPER 26 -477.4 -477403 4.6 PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SNRPA ENSG00000269843 FBL ITPKC CCDC97 ENSG00000205041 PSMC4 COQ8B ENSG00000269069 RNU6-195P
GH19G041294 2.1 FANTOM5 Ensembl ENCODE dbSUPER 15.1 -6.9 -6893 16.8 MLX CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YBX1 YY1 ZNF416 ZNF143 SNRPA ZNF526 ENSG00000269843 ZNF574 TGFB1 TMEM91 ITPKC HNRNPUL1 CCDC97 B9D2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCDC97 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC97 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000109639 211 1601 MLX CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YBX1 YY1 ZNF416 ZNF143

Genomic Location for CCDC97 Gene

Chromosome:
19
Start:
41,310,189 bp from pter
End:
41,324,883 bp from pter
Size:
14,695 bases
Orientation:
Plus strand

Genomic View for CCDC97 Gene

Genes around CCDC97 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC97 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC97 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC97 Gene

Proteins for CCDC97 Gene

  • Protein details for CCDC97 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96F63-CCD97_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 97
    Protein Accession:
    Q96F63
    Secondary Accessions:
    • Q658N6
    • Q96IF3

    Protein attributes for CCDC97 Gene

    Size:
    343 amino acids
    Molecular mass:
    38947 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC97 Gene

Post-translational modifications for CCDC97 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC97 Gene

No data available for DME Specific Peptides for CCDC97 Gene

Domains & Families for CCDC97 Gene

Protein Domains for CCDC97 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC97 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC97: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC97 Gene

Function for CCDC97 Gene

Phenotypes for CCDC97 Gene

genes like me logo Genes that share phenotypes with CCDC97: view

Animal Model Products

CRISPR Products

miRNA for CCDC97 Gene

miRTarBase miRNAs that target CCDC97

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC97 Gene

Localization for CCDC97 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC97 gene
Compartment Confidence
nucleus 5
cytosol 3
plasma membrane 2

Gene Ontology (GO) - Cellular Components for CCDC97 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005686 U2 snRNP IBA --
genes like me logo Genes that share ontologies with CCDC97: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CCDC97 Gene

Pathways & Interactions for CCDC97 Gene

SuperPathways for CCDC97 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC97 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC97 Gene

Transcripts for CCDC97 Gene

Unigene Clusters for CCDC97 Gene

Coiled-coil domain containing 97:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC97 Gene

No ASD Table

Relevant External Links for CCDC97 Gene

GeneLoc Exon Structure for
CCDC97
ECgene alternative splicing isoforms for
CCDC97

Expression for CCDC97 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC97 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CCDC97 Gene

This gene is overexpressed in Blymphocyte (19.5) and Testis (11.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CCDC97 Gene



Protein tissue co-expression partners for CCDC97 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CCDC97 Gene:

CCDC97

SOURCE GeneReport for Unigene cluster for CCDC97 Gene:

Hs.437497

Evidence on tissue expression from TISSUES for CCDC97 Gene

  • Stomach(4.2)
genes like me logo Genes that share expression patterns with CCDC97: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC97 Gene

Orthologs for CCDC97 Gene

This gene was present in the common ancestor of animals.

Orthologs for CCDC97 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC97 35
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC97 34 35
  • 87.29 (n)
cow
(Bos Taurus)
Mammalia CCDC97 34 35
  • 85.92 (n)
rat
(Rattus norvegicus)
Mammalia Ccdc97 34
  • 79.94 (n)
mouse
(Mus musculus)
Mammalia Ccdc97 34 16 35
  • 79.74 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC97 35
  • 64 (a)
OneToOne
chicken
(Gallus gallus)
Aves LOC101748852 34
  • 57.58 (n)
lizard
(Anolis carolinensis)
Reptilia CCDC97 35
  • 56 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc97 34
  • 60.08 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC793800 34
  • 54.58 (n)
CCDC97 35
  • 40 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG7810 35
  • 26 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea R10D12.13 35
  • 27 (a)
OneToOne
Species where no ortholog for CCDC97 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CCDC97 Gene

ENSEMBL:
Gene Tree for CCDC97 (if available)
TreeFam:
Gene Tree for CCDC97 (if available)

Paralogs for CCDC97 Gene

No data available for Paralogs for CCDC97 Gene

Variants for CCDC97 Gene

Sequence variations from dbSNP and Humsavar for CCDC97 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000226840 -- 41,323,608(+) ACTCT(A/C)CCCTT utr-variant-3-prime
rs1000263906 -- 41,320,887(+) CTGCA(C/G/T)TGGCT intron-variant, utr-variant-3-prime
rs1000317775 -- 41,309,546(+) TGACG(A/G)AAGTA nc-transcript-variant, upstream-variant-2KB
rs1000491727 -- 41,315,920(+) AATAC(A/C/T)CTGTC intron-variant
rs1000558823 -- 41,317,272(+) AAACC(A/G)TGAAG intron-variant

Variation tolerance for CCDC97 Gene

Residual Variation Intolerance Score: 55.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.15; 23.31% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC97 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC97

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCDC97 Gene

Disorders for CCDC97 Gene

Relevant External Links for CCDC97

Genetic Association Database (GAD)
CCDC97
Human Genome Epidemiology (HuGE) Navigator
CCDC97
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC97

No disorders were found for CCDC97 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC97 Gene

Publications for CCDC97 Gene

  1. Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey L.T. … Malats N. (Eur. Urol. 2010) 3 46 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  4. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3 64
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64

Products for CCDC97 Gene

Sources for CCDC97 Gene

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