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CCDC97 Gene

protein-coding   GIFtS: 46
GCID: GC19P041816

Coiled-Coil Domain Containing 97

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disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Coiled-Coil Domain Containing 971 2
Coiled-Coil Domain-Containing Protein 972

External Ids:    HGNC: 282891   Entrez Gene: 903242   Ensembl: ENSG000001420397   UniProtKB: Q96F633   

Export aliases for CCDC97 gene to outside databases

Previous GC identifers: GC19P046508 GC19P038249


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CCDC97 Gene:
CCDC97 (coiled-coil domain containing 97) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CCDC97 gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-2   Max   E2F   E2F-1   FOXO4   ZIC2/Zic2   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCDC97 promoter sequence
   Search Chromatin IP Primers for CCDC97

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC97


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.2   Ensembl cytogenetic band:  19q13.2   HGNC cytogenetic band: 19q13.2

CCDC97 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCDC97 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P041816:  view genomic region     (about GC identifiers)

Start:
41,816,094 bp from pter      End:
41,830,788 bp from pter
Size:
14,695 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CCD97_HUMAN, Q96F63 (See protein sequence)
Recommended Name: Coiled-coil domain-containing protein 97  
Size: 343 amino acids; 38947 Da
Secondary accessions: Q658N6 Q96IF3

Explore the universe of human proteins at neXtProt for CCDC97: NX_Q96F63

Explore proteomics data for CCDC97 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CCDC97 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_443080.1  
    ENSEMBL proteins: 
     ENSP00000269967   ENSP00000470858   ENSP00000469348  

    CCDC97 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for CCDC97

     
    Search eBioscience for Proteins for CCDC97 

     
    antibodies-online proteins for CCDC97 (3 products) 

     
    antibodies-online peptides for CCDC97

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    antibodies-online antibodies for CCDC97 (11 products) 

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    Cloud-Clone Corp. CLIAs for CCDC97
    Search eBioscience for ELISAs for CCDC97 
    antibodies-online kits for CCDC97 (16 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR018613 DUF2052_coiled-coil

    Graphical View of Domain Structure for InterPro Entry Q96F63

    ProtoNet protein and cluster: Q96F63


    Find genes that share domains with CCDC97           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for CCDC97

    miRNA
    Products:
        
    miRTarBase miRNAs that target CCDC97:
    hsa-let-7e-5p (MIRT051643), hsa-mir-484 (MIRT042047)

    Block miRNA regulation of human, mouse, rat CCDC97 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CCDC97 (see all 35):
    hsa-miR-1260b hsa-miR-486-3p hsa-miR-30d hsa-miR-30a hsa-miR-149 hsa-miR-637 hsa-miR-510 hsa-miR-3175
    SwitchGear 3'UTR luciferase reporter plasmidCCDC97 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CCDC97
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC97

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    GenScript: all cDNA clones in your preferred vector: CCDC97 (NM_052848)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC97
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC97

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC97


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3
    plasma membrane3

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CCDC97
    Interactions:

        Search GeneGlobe Interaction Network for CCDC97

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for CCDC97 (Q96F633 ENSP000002699674) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APBB1O002133, ENSP000002994024I2D: score=2 STRING: ENSP00000299402
    MAPK14Q165393, ENSP000002297944I2D: score=3 STRING: ENSP00000229794
    SF3B1ENSP000003353214STRING: ENSP00000335321
    SF3B3ENSP000003057904STRING: ENSP00000305790
    SF3B5ENSP000003565414STRING: ENSP00000356541
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CCDC97 (CCD97)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CCDC97 gene: 
    NM_052848.1  

    Unigene Cluster for CCDC97:

    Coiled-coil domain containing 97
    Hs.437497  [show with all ESTs]
    Unigene Representative Sequence: BC011577
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000269967(uc002oqg.3) ENST00000596882 ENST00000600918
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CCDC97 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CCDC97 (see all 35):
    hsa-miR-1260b hsa-miR-486-3p hsa-miR-30d hsa-miR-30a hsa-miR-149 hsa-miR-637 hsa-miR-510 hsa-miR-3175
    SwitchGear 3'UTR luciferase reporter plasmidCCDC97 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CCDC97
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC97
    Clone
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    OriGene clones in human, mouse for CCDC97 (see all 7)
    OriGene ORF clones in mouse, rat for CCDC97
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CCDC97 (NM_052848)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC97
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC97
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CCDC97
    OriGene qSTAR qPCR primer pairs in human, mouse for CCDC97
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC97
      QuantiTect SYBR Green Assays in human, mouse, rat CCDC97
      QuantiFast Probe-based Assays in human, mouse, rat CCDC97

    Additional mRNA sequence: 

    AK097586.1 AL833726.1 BC007575.1 BC011577.1 BC019597.1 

    10 DOTS entries:

    DT.92462604  DT.100816245  DT.100816243  DT.87017399  DT.121637306  DT.75169165  DT.97823041  DT.100816253 
    DT.92462564  DT.95101717 

    Selected AceView cDNA sequences (see all 202):

    AI478301 BE906847 AI263807 AW087414 BU738495 AI417216 BM802063 CD360006 
    BC019597 BM713037 BQ057906 AI701431 BQ186354 CF264742 BF811124 BC007575 
    NM_052848 AL833726 BM718385 BU553866 AI470486 AA622438 AI709059 BU956121 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CCDC97 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGATGTCCT
    CCDC97 Expression
    About this image


    CCDC97 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Brain (Nervous System)
             Cerebellum
    CCDC97 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CCDC97 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.437497
        Custom PCR Arrays for CCDC97
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CCDC97
    OriGene qSTAR qPCR primer pairs in human, mouse for CCDC97
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC97
    QuantiTect SYBR Green Assays in human, mouse, rat CCDC97
    QuantiFast Probe-based Assays in human, mouse, rat CCDC97
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC97

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CCDC97 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccdc971 , 5 coiled-coil domain containing 971, 5 79.74(n)1
    79.06(a)1
      7 (13.99 cM)5
    521321  NM_028771.21  NP_083047.11 
     257111065 
    chicken
    (Gallus gallus)
    Aves LOC1017488521 coiled-coil domain-containing protein 97-like 57.58(n)
    50.76(a)
      101748852  XM_004950443.1  XP_004950500.1 
    lizard
    (Anolis carolinensis)
    Reptilia CCDC976
    coiled-coil domain containing 97
    56(a)
    1 ↔ 1
    LGf(3685735-3693025)
    African clawed frog
    (Xenopus laevis)
    Amphibia CF289743.12   -- 76.94(n)    CF289743.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC7938001 coiled-coil domain-containing protein 97-like 54.58(n)
    49.3(a)
      793800  XM_001333080.3  XP_001333116.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG78106
    --
    26(a)
    1 ↔ 1
    2L(8309876-8311195)
    worm
    (Caenorhabditis elegans)
    Secernentea R10D12.136
    Protein R10D12.13, isoform b
    27(a)
    1 ↔ 1
    V(13962417-13963840) WBGene00011194


    ENSEMBL Gene Tree for CCDC97 (if available)
    TreeFam Gene Tree for CCDC97 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CCDC97 (see all 363)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs18650531,2
    C,F,O,A,H--41814412(-) TGCCCA/GTCTCC 1 -- us2k125Minor allele frequency- G:0.26MN NS EA NA WA CSA 2851
    rs1130487181,2
    C--41814445(+) GACTAA/GTCTCA 1 -- us2k10--------
    rs1504210801,2
    --41814514(+) CCCTAC/GAATGC 1 -- us2k10--------
    rs621209671,2
    C,F--41814516(+) CTAGAA/GTGCGC 1 -- us2k12Minor allele frequency- G:0.02NA 122
    rs1891785951,2
    --41814553(+) TCTGGA/GAAGTC 1 -- us2k10--------
    rs1452691131,2
    C--41814560(+) AGTCCC/TCTTCC 1 -- us2k10--------
    rs1148249671,2
    F--41814593(+) ACAGCG/ACCCTC 1 -- us2k11Minor allele frequency- A:0.02WA 118
    rs1491338461,2
    --41814738(+) CACGTC/GTCATC 1 -- us2k10--------
    rs22176561,2
    C,F,O,H--41814897(-) CCTCAG/TAACAA 1 -- us2k119Minor allele frequency- T:0.10NA NS EA WA 2254
    rs790895681,2
    C,F--41815092(+) GAACCG/ATCCGT 1 -- us2k12Minor allele frequency- A:0.04NA 122

    HapMap Linkage Disequilibrium report for CCDC97 (41816094 - 41830788 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CCDC97:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv911769CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CCDC97
    DNA2.0 Custom Variant and Variant Library Synthesis for CCDC97

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with CCDC97           About GenesLikeMe

    Genetic Association Database (GAD): CCDC97
    Human Genome Epidemiology (HuGE) Navigator: CCDC97 (1 document)

    Export disorders for CCDC97 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CCDC97 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with CCDC97)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic susceptibility to distinct bladder cancer subphenotypes. (PubMed id 19692168)1, 4 Guey L.T....Malats N. (Eur. Urol. 2010)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    6. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (Nat. Methods 2010)
    7. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R.... Peters J.M. (Science 2010)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    9. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 90324 HGNC: 28289 AceView: MGC20255 Ensembl:ENSG00000142039 euGenes: HUgn90324
    ECgene: CCDC97 H-InvDB: CCDC97

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CCDC97 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CCDC97 gene:
    Search GeneIP for patents involving CCDC97

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
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