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Aliases for CCDC96 Gene

Aliases for CCDC96 Gene

  • Coiled-Coil Domain Containing 96 2 3 5

External Ids for CCDC96 Gene

Previous GeneCards Identifiers for CCDC96 Gene

  • GC04M007093

Summaries for CCDC96 Gene

GeneCards Summary for CCDC96 Gene

CCDC96 (Coiled-Coil Domain Containing 96) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC96 Gene

Genomics for CCDC96 Gene

Regulatory Elements for CCDC96 Gene

Enhancers for CCDC96 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04G006961 1.6 FANTOM5 Ensembl ENCODE dbSUPER 5.4 +79.2 79206 4.2 HDGF BMI1 RAD21 ZBTB40 RARA ZNF143 FOS RELB ETV6 IKZF2 GRPEL1 TBC1D14 CCDC96 GC04P006943 GC04M006985
GH04G007041 1 ENCODE 0.7 -0.5 -480 3.5 HDGF PKNOX1 ATF1 CREB3L1 ZFP64 WRNIP1 ARID4B SIN3A DMAP1 GLI4 GRPEL1 CCDC96 LOC100129931
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCDC96 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC96 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000165515 -499 2201 HDGF PKNOX1 ATF1 ZFP64 ARID4B SIN3A GLI4 ZNF48 YY1 GLIS2

Genomic Location for CCDC96 Gene

Chromosome:
4
Start:
7,040,849 bp from pter
End:
7,043,001 bp from pter
Size:
2,153 bases
Orientation:
Minus strand

Genomic View for CCDC96 Gene

Genes around CCDC96 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC96 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC96 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC96 Gene

Proteins for CCDC96 Gene

  • Protein details for CCDC96 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q2M329-CCD96_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 96
    Protein Accession:
    Q2M329
    Secondary Accessions:
    • Q8N2I7

    Protein attributes for CCDC96 Gene

    Size:
    555 amino acids
    Molecular mass:
    62711 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC96 Gene

Post-translational modifications for CCDC96 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC96 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC96 Gene

Domains & Families for CCDC96 Gene

Protein Domains for CCDC96 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC96 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC96: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC96 Gene

Function for CCDC96 Gene

genes like me logo Genes that share phenotypes with CCDC96: view

Animal Model Products

CRISPR Products

miRNA for CCDC96 Gene

miRTarBase miRNAs that target CCDC96

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC96 Gene

Localization for CCDC96 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC96 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC96 gene
Compartment Confidence
cytoskeleton 3
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for CCDC96 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005815 microtubule organizing center IEA --
GO:0005856 cytoskeleton IEA --
genes like me logo Genes that share ontologies with CCDC96: view

Pathways & Interactions for CCDC96 Gene

SuperPathways for CCDC96 Gene

No Data Available

Interacting Proteins for CCDC96 Gene

Gene Ontology (GO) - Biological Process for CCDC96 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC96 Gene

Drugs & Compounds for CCDC96 Gene

No Compound Related Data Available

Transcripts for CCDC96 Gene

mRNA/cDNA for CCDC96 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(17) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC96 Gene

Coiled-coil domain containing 96:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC96 Gene

No ASD Table

Relevant External Links for CCDC96 Gene

GeneLoc Exon Structure for
CCDC96
ECgene alternative splicing isoforms for
CCDC96

Expression for CCDC96 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC96 Gene

Protein differential expression in normal tissues from HIPED for CCDC96 Gene

This gene is overexpressed in Plasma (45.4) and Lymph node (10.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC96 Gene



Protein tissue co-expression partners for CCDC96 Gene

NURSA nuclear receptor signaling pathways regulating expression of CCDC96 Gene:

CCDC96

SOURCE GeneReport for Unigene cluster for CCDC96 Gene:

Hs.656757

Evidence on tissue expression from TISSUES for CCDC96 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with CCDC96: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC96 Gene

Orthologs for CCDC96 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC96 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC96 34 35
  • 98.32 (n)
dog
(Canis familiaris)
Mammalia CCDC96 34 35
  • 83.91 (n)
cow
(Bos Taurus)
Mammalia CCDC96 34 35
  • 82.37 (n)
mouse
(Mus musculus)
Mammalia Ccdc96 34 16 35
  • 76.74 (n)
rat
(Rattus norvegicus)
Mammalia Ccdc96 34
  • 76.67 (n)
oppossum
(Monodelphis domestica)
Mammalia CCDC96 35
  • 62 (a)
OneToOne
chicken
(Gallus gallus)
Aves CCDC96 34 35
  • 55.38 (n)
lizard
(Anolis carolinensis)
Reptilia CCDC96 35
  • 43 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.11474 34
zebrafish
(Danio rerio)
Actinopterygii ccdc96 35
  • 35 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 40 (a)
OneToOne
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.14252 34
Species where no ortholog for CCDC96 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC96 Gene

ENSEMBL:
Gene Tree for CCDC96 (if available)
TreeFam:
Gene Tree for CCDC96 (if available)

Paralogs for CCDC96 Gene

No data available for Paralogs for CCDC96 Gene

Variants for CCDC96 Gene

Sequence variations from dbSNP and Humsavar for CCDC96 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1000019212 -- 7,040,909(+) CTTGC(C/T)CATTC intron-variant, utr-variant-3-prime
rs1000346404 -- 7,042,451(+) CCCGC(C/T)CTGTC intron-variant, upstream-variant-2KB, reference, missense
rs1001641969 -- 7,043,021(+) CTGGG(C/T)CCGGC intron-variant, upstream-variant-2KB
rs1002654447 -- 7,044,775(+) TCTTC(C/T)CCTGC intron-variant, upstream-variant-2KB
rs1002792615 -- 7,043,949(+) GCTCG(C/T)TCCGC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CCDC96 Gene

Variant ID Type Subtype PubMed ID
dgv8941n54 CNV gain 21841781
esv26516 CNV loss 19812545
esv2759221 CNV gain 17122850
esv34033 CNV loss 18971310
esv34196 OTHER inversion 12058347
nsv4217 CNV deletion 18451855
nsv428436 CNV gain 18775914
nsv469847 CNV gain 16826518
nsv593548 CNV loss 21841781
nsv593549 CNV gain+loss 21841781
nsv593550 CNV gain 21841781
nsv593556 CNV gain 21841781

Variation tolerance for CCDC96 Gene

Residual Variation Intolerance Score: 30.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.49; 43.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC96 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC96

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC96 Gene

Disorders for CCDC96 Gene

Relevant External Links for CCDC96

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC96

No disorders were found for CCDC96 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC96 Gene

Publications for CCDC96 Gene

  1. Proteomic analysis of mammalian sperm cells identifies new components of the centrosome. (PMID: 25074808) Firat-Karalar E.N. … Stearns T. (J. Cell Sci. 2014) 2 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for CCDC96 Gene

Sources for CCDC96 Gene

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