CCDC92 Gene
protein-coding GIFtS : 45
GCID: GC12 M124403
coiled-coil domain containing 92
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Aliasesfor CCDC92 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Coiled-Coil Domain Containing 92 1 2 Limkain Beta-22 3 FLJ224711 Coiled-Coil Domain-Containing Protein 922 Limkain Beta 22
Export aliases for CCDC92 gene to outside databases Previous GC identifers: GC12M122986 GC12M124420 GC12M121383
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Summariesfor CCDC92 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor CCDC92 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000012.11 NC_018923.1 NT_009755.19 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the CCDC92 gene promoter: STAT5A E4BP4 c-Ets-1 Evi-1 Arnt Hand1 Sox9 Pax-4a ATF Other transcription factors Search SABiosciences Chromatin IP Primers for CCDC92 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC92
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 12q24.31 Ensembl cytogenetic band: 12q24.31 HGNC cytogenetic band: 12q24.31 CCDC92 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 12 GeneLoc Exon Structure
GeneLoc location for GC12M124403: view genomic region
(about GC identifiers )
Start:
124,403,207 bp from pter
End:
124,457,378 bp from pter
Size:
54,172 bases
Orientation:
minus strand
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Proteinsfor CCDC92 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: CCD92_HUMAN, Q53HC0 (See
protein sequence )Recommended Name: Coiled-coil domain-containing protein 92 Size : 331 amino acids; 36961 Da
Subunit : Interacts with CEP164
Subcellular location : Cytoplasm, cytoskeleton, centrosome, centriole
Caution : It is uncertain whether Met-1 or Met-18 is the initiator
Sequence caution : Sequence=BAD96381.1; Type=Erroneous initiation;
Secondary accessions : Q9H697Explore the universe of human proteins at neXtProt for CCDC92: NX_Q53HC0 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q53HC0 CCDC92 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_079416.1 ENSEMBL proteins: ENSP00000238156 ENSP00000439526 ENSP00000440024 ENSP00000439441 ENSP00000438281 ENSP00000442369 ENSP00000440203 Human Recombinant Protein Products for CCDC92: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005814 centriole
IDA --
CCDC92 for ontologies About GeneDecksing CCDC92 Antibody Products: Assay Products for CCDC92:
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Protein
Domains / Familiesfor CCDC92 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section ProtoNet protein and cluster: Q53HC0
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Functionfor CCDC92 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Gene Ontology (GO): 1 molecular function term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005515 protein binding
IPI --
CCDC92 for ontologies About GeneDecksing Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for CCDC92 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for CCDC92OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: CCDC92 (NM_025140 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC92 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CCDC92
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC92
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Pathways & Interactionsfor CCDC92 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC92 STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)5 Interacting proteins for CCDC92 (Q53HC0 1 , 2 , 3 ENSP00000238156 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table
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Drugs & Compoundsfor CCDC92 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for CCDC92 Search CenterWatch for drugs/clinical trials and news about CCDC92 / CCD92
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Transcriptsfor CCDC92 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for CCDC92 gene: NM_025140.1 Unigene Cluster for CCDC92:
Coiled-coil domain containing 92 Hs.713131 [show with all ESTs ] Unigene Representative Sequence: AK125866 9 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000542348 ENST00000544798 ENST00000238156 (uc001ufw.1 uc001ufx.1 )ENST00000545135 (uc001ufv.1 ) ENST00000545891 ENST00000539761 ENST00000535556 ENST00000539551 ENST00000545037 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for CCDC92 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for CCDC92OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: CCDC92 (NM_025140 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC92 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CCDC92
Additional cDNA sequence: AB015292.1 AK026124.1 AK054680.1 AK124358.1 AK125866.1 AK222661.1 BC017186.2
16 DOTS entries : DT.100807651 DT.116997
DT.100807652 DT.121181357 DT.95188846 DT.97824143 DT.101957962 DT.92431952 DT.121181342 DT.92431949 DT.100694037 DT.121181388 DT.97803349 DT.100807653 DT.40254034 DT.95186409 1 AceView cDNA sequence :
NM_025140 GeneLoc Exon Structure 5/10 Alternative Splicing Database (ASD) splice patterns (SP) for CCDC92 (see all 10 ) About this scheme ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c · 10d · 10e · 10f · 10g · 10h SP1 :     -   -   -   -   -     -   -   -                             SP2 :         -   -   -     -                                 SP3 :               -   -   -   -                             SP4 :     -   -   -   -   -   -   -   -   -                             SP5 :     -   -   -   -   -   -   -   -   -   -                          
ECgene alternative splicing isoforms for CCDC92
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Expression for CCDC92 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section CCDC92 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: CCAAACACTTAbout this image CCDC92 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
See CCDC92 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CCDC92 SOURCE GeneReport for Unigene cluster: Hs.713131 SABiosciences Custom PCR Arrays for CCDC92 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for CCDC92Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat CCDC92 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat CCDC92 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat CCDC92 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC92
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Orthologsfor CCDC92 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for CCDC92 gene from 4/15 species (see all 15 ) About this table
ENSEMBL Gene Tree for CCDC92 (if available)TreeFam Gene Tree for CCDC92 (if available)
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Paralogsfor CCDC92 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor CCDC92 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 12 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for CCDC92 (124403207 - 124457378 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for CCDC92: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing CCDC92
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Disorders
/ Diseasesfor CCDC92 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
CCDC92 for disorders About GeneDecksing 1 disease for CCDC92 : About MalaCards cholesterol Human Genome Epidemiology (HuGE) Navigator: CCDC92 (1 document)Export disorders for CCDC92 gene to outside databases
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Publicationsfor CCDC92 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for CCDC92 gene, integrated from 9 sources (see all 12 ): (articles sorted by number of sources associating them with CCDC92) Utopia : connect your pdf to the dynamic world of online information
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 , 3 Strausberg R.L....Marra M.A. (2002) Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. (PubMed id 22863007) 2 Chaki M....Hildebrandt F. (2012) A human MAP kinase interactome. (PubMed id 20936779) 1 Bandyopadhyay S....Ideker T. (2010) Biological, clinical and population relevance of 95 l oci for blood lipids. (PubMed id 20686565) 1 Teslovich T.M....Kathiresan S. (2010) Forty-three loci associated with plasma lipoprotein s ize, concentration, and cholesterol content in genome-wide analysis. (PubMed id 19936222) 1 Chasman D.I....Ridker P.M. (2009) Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201) 1 Abdelmohsen K....Gorospe M. (2009) hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965) 1 Lamesch P.... Vidal M. (2007) A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070) 1 Stelzl U.... Wanker E.E. (2005)
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External Searches for CCDC92 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing CCDC92 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing CCDC92 gene
(According to HUGE )
About This Section --
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Specialized Databases showing CCDC92 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for CCDC92 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for CCDC92 gene: Search GeneIP for patents involving CCDC92 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor CCDC92 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for CCDC92 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for CCDC92 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for CCDC92 Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for CCDC92 OriGene 3'-UTR Clone for CCDC92 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for CCDC92 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for CCDC92 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for CCDC92 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for CCDC92 OriGene Custom Protein Services for CCDC92 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC92 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing CCDC92 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC92 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat CCDC92 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat CCDC92 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat CCDC92
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CCDC92 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC92
ThermoFisher Antibodies for CCDC92
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CCDC92
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