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Aliases for CCDC92 Gene

Aliases for CCDC92 Gene

  • Coiled-Coil Domain Containing 92 2 3 5
  • Limkain Beta 2 2
  • Limkain Beta-2 4

External Ids for CCDC92 Gene

Previous GeneCards Identifiers for CCDC92 Gene

  • GC12M122986
  • GC12M124420
  • GC12M121383
  • GC12M124403

Summaries for CCDC92 Gene

GeneCards Summary for CCDC92 Gene

CCDC92 (Coiled-Coil Domain Containing 92) is a Protein Coding gene.

Additional gene information for CCDC92 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC92 Gene

Genomics for CCDC92 Gene

Regulatory Elements for CCDC92 Gene

Enhancers for CCDC92 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12H124029 1.3 Ensembl ENCODE dbSUPER 20 -57.8 -57779 1.8 PKNOX1 ZNF146 MAX ZIC2 FOSL1 CTBP1 FOXK2 EGR1 POLR2A SCRT2 CCDC92 RFLNA ZNF664 DNAH10OS PIR55353 ENSG00000275389
GH12H123937 0.9 Ensembl ENCODE 27 +34.8 34791 2 CTCF PKNOX1 MAZ MAFG RAD21 CTBP1 ZNF316 ZNF341 RUNX3 SPI1 CCDC92 DNAH10OS ZNF664 PIR47036 PIR34615
GH12H124913 2.2 FANTOM5 Ensembl ENCODE dbSUPER 10.4 -946.2 -946198 12.7 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF548 SP3 NFYC NCOR2 DHX37 ENSG00000269938 ENSG00000270130 ENSG00000269997 ENSG00000270061 DNAH10OS LOC100131779 ENSG00000256814 SCARB1
GH12H123988 1.1 ENCODE dbSUPER 16.5 -18.4 -18374 5 ATF1 FEZF1 GATA2 ZNF366 SCRT2 ATF7 CREM CEBPB NFIC IKZF1 DNAH10 DNAH10OS CCDC92 ZNF664 ENSG00000256827 ENSG00000274874
GH12H123968 1 Ensembl ENCODE dbSUPER 17.4 +3.7 3663 1 ZNF362 FOS MAFK CCDC92 ENSG00000270061 ENSG00000269938
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCDC92 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC92 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000058798 -15 3201 ARID4B SIN3A YY1 ETS1 GLIS2 ELK1 ZNF143 RUNX3 SP3 YY2

Genomic Locations for CCDC92 Gene

Genomic Locations for CCDC92 Gene
54,326 bases
Minus strand

Genomic View for CCDC92 Gene

Genes around CCDC92 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC92 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC92 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC92 Gene

Proteins for CCDC92 Gene

  • Protein details for CCDC92 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 92
    Protein Accession:
    Secondary Accessions:
    • B3KNQ0
    • Q9H697

    Protein attributes for CCDC92 Gene

    331 amino acids
    Molecular mass:
    36961 Da
    Quaternary structure:
    • Interacts with CEP164.
    • Sequence=BAD96381.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC92 Gene


neXtProt entry for CCDC92 Gene

Post-translational modifications for CCDC92 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC92 Gene

Domains & Families for CCDC92 Gene

Gene Families for CCDC92 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC92 Gene


Suggested Antigen Peptide Sequences for CCDC92 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC92: view

No data available for UniProtKB/Swiss-Prot for CCDC92 Gene

Function for CCDC92 Gene

Phenotypes From GWAS Catalog for CCDC92 Gene

Gene Ontology (GO) - Molecular Function for CCDC92 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 22458338
genes like me logo Genes that share ontologies with CCDC92: view
genes like me logo Genes that share phenotypes with CCDC92: view

Animal Models for CCDC92 Gene

MGI Knock Outs for CCDC92:

miRNA for CCDC92 Gene

miRTarBase miRNAs that target CCDC92

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CCDC92 Gene

Localization for CCDC92 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC92 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC92 gene
Compartment Confidence
cytoskeleton 5
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Centrosome (3)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CCDC92 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IEA --
GO:0005813 centrosome IDA --
GO:0005814 centriole IDA,IEA 22863007
GO:0005856 cytoskeleton IEA --
genes like me logo Genes that share ontologies with CCDC92: view

Pathways & Interactions for CCDC92 Gene

SuperPathways for CCDC92 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC92 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC92 Gene

Drugs & Compounds for CCDC92 Gene

No Compound Related Data Available

Transcripts for CCDC92 Gene

mRNA/cDNA for CCDC92 Gene

(8) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC92 Gene

Coiled-coil domain containing 92:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC92 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c · 10d · 10e · 10f · 10g · 10h
SP1: - - - - - - - -
SP2: - - - -
SP3: - - - -
SP4: - - - - - - - - -
SP5: - - - - - - - - - -
SP6: - - - - - - -
SP7: - - - - - -
SP8: - - - - - -

Relevant External Links for CCDC92 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC92 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC92 Gene

Protein differential expression in normal tissues from HIPED for CCDC92 Gene

This gene is overexpressed in Ovary (31.3) and Monocytes (9.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CCDC92 Gene

Protein tissue co-expression partners for CCDC92 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CCDC92 Gene:


SOURCE GeneReport for Unigene cluster for CCDC92 Gene:


Evidence on tissue expression from TISSUES for CCDC92 Gene

  • Nervous system(4.8)
  • Intestine(4.2)
  • Liver(4.2)
genes like me logo Genes that share expression patterns with CCDC92: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC92 Gene

Orthologs for CCDC92 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC92 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CCDC92 33 34
  • 98.29 (n)
(Bos Taurus)
Mammalia CCDC92 33 34
  • 87.15 (n)
(Canis familiaris)
Mammalia CCDC92 33 34
  • 86.52 (n)
(Ornithorhynchus anatinus)
Mammalia CCDC92 34
  • 83 (a)
(Rattus norvegicus)
Mammalia Ccdc92 33
  • 82 (n)
(Mus musculus)
Mammalia Ccdc92 33 16 34
  • 81.58 (n)
(Monodelphis domestica)
Mammalia CCDC92 34
  • 78 (a)
(Gallus gallus)
Aves CCDC92 33 34
  • 75.48 (n)
(Anolis carolinensis)
Reptilia CCDC92 34
  • 85 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc92 33
  • 72.9 (n)
(Danio rerio)
Actinopterygii ccdc92 33 34
  • 66.77 (n)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.7515 33
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 30 (a)
Species where no ortholog for CCDC92 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC92 Gene

Gene Tree for CCDC92 (if available)
Gene Tree for CCDC92 (if available)

Paralogs for CCDC92 Gene

No data available for Paralogs for CCDC92 Gene

Variants for CCDC92 Gene

Sequence variations from dbSNP and Humsavar for CCDC92 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1000003607 -- 123,937,694(+) GTGTT(C/T)TCCAG reference, synonymous-codon
rs1000089831 -- 123,938,910(+) CCAGC(A/C/T)GGCCT intron-variant
rs1000176913 -- 123,957,649(+) CCAAA(C/T)TTCTA intron-variant, upstream-variant-2KB
rs1000246229 -- 123,963,021(+) GTGCC(C/T)CCAGG intron-variant
rs1000351428 -- 123,973,221(+) GCTGT(-/C)CCCCC upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for CCDC92 Gene

Variant ID Type Subtype PubMed ID
nsv522321 CNV loss 19592680
nsv1116712 CNV tandem duplication 24896259
nsv1115971 CNV insertion 24896259
esv3302753 CNV tandem duplication 20981092
esv1305470 CNV insertion 17803354

Variation tolerance for CCDC92 Gene

Residual Variation Intolerance Score: 41.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.63; 86.29% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC92 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC92 Gene

Disorders for CCDC92 Gene

Relevant External Links for CCDC92

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC92 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC92 Gene

Publications for CCDC92 Gene

  1. Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. (PMID: 22863007) Chaki M … Hildebrandt F (Cell 2012) 3 4 60
  2. Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis. (PMID: 19936222) Chasman DI … Ridker PM (PLoS genetics 2009) 3 45 60
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60

Products for CCDC92 Gene

Sources for CCDC92 Gene

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