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Aliases for CCDC92 Gene

Aliases for CCDC92 Gene

  • Coiled-Coil Domain Containing 92 2 3 5
  • Limkain Beta 2 2
  • Limkain Beta-2 4

External Ids for CCDC92 Gene

Previous GeneCards Identifiers for CCDC92 Gene

  • GC12M122986
  • GC12M124420
  • GC12M121383
  • GC12M124403

Summaries for CCDC92 Gene

GeneCards Summary for CCDC92 Gene

CCDC92 (Coiled-Coil Domain Containing 92) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC92 Gene

Genomics for CCDC92 Gene

Regulatory Elements for CCDC92 Gene

Promoters for CCDC92 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC92 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC92 Gene

Chromosome:
12
Start:
123,918,660 bp from pter
End:
123,972,985 bp from pter
Size:
54,326 bases
Orientation:
Minus strand

Genomic View for CCDC92 Gene

Genes around CCDC92 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC92 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC92 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC92 Gene

Proteins for CCDC92 Gene

  • Protein details for CCDC92 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q53HC0-CCD92_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 92
    Protein Accession:
    Q53HC0
    Secondary Accessions:
    • B3KNQ0
    • Q9H697

    Protein attributes for CCDC92 Gene

    Size:
    331 amino acids
    Molecular mass:
    36961 Da
    Quaternary structure:
    • Interacts with CEP164.
    SequenceCaution:
    • Sequence=BAD96381.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC92 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC92 Gene

Proteomics data for CCDC92 Gene at MOPED

Post-translational modifications for CCDC92 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for CCDC92 Gene

Domains & Families for CCDC92 Gene

Protein Domains for CCDC92 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CCDC92 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC92: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC92 Gene

Function for CCDC92 Gene

Phenotypes for CCDC92 Gene

genes like me logo Genes that share phenotypes with CCDC92: view

Animal Models for CCDC92 Gene

MGI Knock Outs for CCDC92:

Animal Model Products

miRNA for CCDC92 Gene

miRTarBase miRNAs that target CCDC92

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CCDC92 Gene

Localization for CCDC92 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC92 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC92 Gene COMPARTMENTS Subcellular localization image for CCDC92 gene
Compartment Confidence
cytoskeleton 5
nucleus 3
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for CCDC92 Gene

Pathways & Interactions for CCDC92 Gene

SuperPathways for CCDC92 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC92 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC92 Gene

Drugs & Compounds for CCDC92 Gene

No Compound Related Data Available

Transcripts for CCDC92 Gene

mRNA/cDNA for CCDC92 Gene

(7) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC92 Gene

Coiled-coil domain containing 92:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC92 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c · 10d · 10e · 10f · 10g · 10h
SP1: - - - - - - - -
SP2: - - - -
SP3: - - - -
SP4: - - - - - - - - -
SP5: - - - - - - - - - -
SP6: - - - - - - -
SP7: - - - - - -
SP8: - - - - - -
SP9:
SP10:

Relevant External Links for CCDC92 Gene

GeneLoc Exon Structure for
CCDC92
ECgene alternative splicing isoforms for
CCDC92

Expression for CCDC92 Gene

mRNA expression in normal human tissues for CCDC92 Gene

Protein differential expression in normal tissues from HIPED for CCDC92 Gene

This gene is overexpressed in Ovary (31.3) and Monocytes (9.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for CCDC92 Gene



SOURCE GeneReport for Unigene cluster for CCDC92 Gene Hs.713131

genes like me logo Genes that share expression patterns with CCDC92: view

Protein tissue co-expression partners for CCDC92 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CCDC92 Gene

Orthologs for CCDC92 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC92 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC92 35
  • 98.29 (n)
  • 97.88 (a)
CCDC92 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC92 36
  • 90 (a)
OneToOne
CCDC92 35
  • 87.15 (n)
  • 90.76 (a)
dog
(Canis familiaris)
Mammalia CCDC92 35
  • 86.52 (n)
  • 88.89 (a)
CCDC92 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc92 16
Ccdc92 35
  • 81.58 (n)
  • 87.22 (a)
Ccdc92 36
  • 87 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC92 36
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC92 36
  • 83 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc92 35
  • 82 (n)
  • 87.54 (a)
chicken
(Gallus gallus)
Aves CCDC92 35
  • 75.48 (n)
  • 86.94 (a)
CCDC92 36
  • 83 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC92 36
  • 85 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc92 35
  • 72.9 (n)
  • 79.03 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.7515 35
zebrafish
(Danio rerio)
Actinopterygii ccdc92 36
  • 60 (a)
OneToOne
ccdc92 35
  • 66.77 (n)
  • 70.51 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 30 (a)
OneToOne
Species with no ortholog for CCDC92:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC92 Gene

ENSEMBL:
Gene Tree for CCDC92 (if available)
TreeFam:
Gene Tree for CCDC92 (if available)

Paralogs for CCDC92 Gene

No data available for Paralogs for CCDC92 Gene

Variants for CCDC92 Gene

Sequence variations from dbSNP and Humsavar for CCDC92 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs11057401 - 123,942,759(+) CGAAC(A/T)TTTGA reference, missense
rs17886730 - 123,937,212(+) TTTCG(C/T)GGGCC reference, missense
rs35935939 - 123,937,297(+) CTCGG(C/T)GGACT reference, missense
rs9863 -- 123,936,906(-) TTCAC(A/G)CCAAA utr-variant-3-prime
rs939464 -- 123,949,799(+) GGAAG(C/T)GCACT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC92 Gene

Variant ID Type Subtype PubMed ID
nsv522321 CNV Loss 19592680
esv259727 OTHER Complex 20981092
esv1305470 CNV Insertion 17803354

Variation tolerance for CCDC92 Gene

Residual Variation Intolerance Score: 41.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.63; 86.29% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC92 Gene

HapMap Linkage Disequilibrium report
CCDC92
Human Gene Mutation Database (HGMD)
CCDC92

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC92 Gene

Disorders for CCDC92 Gene

Relevant External Links for CCDC92

Genetic Association Database (GAD)
CCDC92
Human Genome Epidemiology (HuGE) Navigator
CCDC92
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC92

No disorders were found for CCDC92 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC92 Gene

Publications for CCDC92 Gene

  1. Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. (PMID: 22863007) Chaki M. … Hildebrandt F. (Cell 2012) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses. (PMID: 22458338) Simonis N. … Twizere J.C. (Retrovirology 2012) 3

Products for CCDC92 Gene

Sources for CCDC92 Gene

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