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Aliases for CCDC91 Gene

Aliases for CCDC91 Gene

  • Coiled-Coil Domain Containing 91 2 3
  • P56 Accessory Protein 3 4
  • GGA Binding Partner 2 3
  • GGA-Binding Partner 3 4
  • Coiled-Coil Domain-Containing Protein 91 3
  • GGABP 4
  • HSD8 3
  • P56 3

External Ids for CCDC91 Gene

Summaries for CCDC91 Gene

GeneCards Summary for CCDC91 Gene

CCDC91 (Coiled-Coil Domain Containing 91) is a Protein Coding gene. GO annotations related to this gene include identical protein binding.

UniProtKB/Swiss-Prot for CCDC91 Gene

  • Involved in the regulation of membrane traffic through the trans-Golgi network (TGN)

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC91 Gene

Genomics for CCDC91 Gene

Genomic Location for CCDC91 Gene

Start:
28,133,249 bp from pter
End:
28,581,511 bp from pter
Size:
448,263 bases
Orientation:
Plus strand

Genomic View for CCDC91 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC91 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC91 Gene

Regulatory Elements for CCDC91 Gene

Proteins for CCDC91 Gene

  • Protein details for CCDC91 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z6B0-CCD91_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 91
    Protein Accession:
    Q7Z6B0
    Secondary Accessions:
    • B3KSA3
    • C9JR07
    • Q68D43
    • Q6IA78
    • Q8NEN7
    • Q9NUW9

    Protein attributes for CCDC91 Gene

    Size:
    441 amino acids
    Molecular mass:
    49971 Da
    Quaternary structure:
    • Homodimer. Interacts with GGA1, GGA2 and AP1G1.
    SequenceCaution:
    • Sequence=BAA91995.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for CCDC91 Gene

    Alternative splice isoforms for CCDC91 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC91 Gene

Proteomics data for CCDC91 Gene at MOPED

Post-translational modifications for CCDC91 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC91 Gene

Domains for CCDC91 Gene

Protein Domains for CCDC91 Gene

ProtoNet:
genes like me logo Genes that share domains with CCDC91: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC91 Gene

Function for CCDC91 Gene

Molecular function for CCDC91 Gene

UniProtKB/Swiss-Prot Function: Involved in the regulation of membrane traffic through the trans-Golgi network (TGN)

Gene Ontology (GO) - Molecular Function for CCDC91 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042802 identical protein binding IEA --
genes like me logo Genes that share ontologies with CCDC91: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC91 Gene

Localization for CCDC91 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC91 Gene

Membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Colocalizes with GGA1 and GGA2. May be recruited to the TGN by GGA1 and GGA2.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC91 Gene COMPARTMENTS Subcellular localization image for CCDC91 gene
Compartment Confidence
golgi apparatus 4
nucleus 4
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for CCDC91 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005654 nucleoplasm IDA --
GO:0005794 Golgi apparatus IDA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with CCDC91: view

Pathways for CCDC91 Gene

SuperPathways for CCDC91 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC91 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015031 protein transport IEA --
genes like me logo Genes that share ontologies with CCDC91: view

No data available for Pathways by source for CCDC91 Gene

Transcripts for CCDC91 Gene

Unigene Clusters for CCDC91 Gene

Coiled-coil domain containing 91:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC91 Gene

No ASD Table

Relevant External Links for CCDC91 Gene

GeneLoc Exon Structure for
CCDC91
ECgene alternative splicing isoforms for
CCDC91

Expression for CCDC91 Gene

mRNA expression in normal human tissues for CCDC91 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CCDC91 Gene

SOURCE GeneReport for Unigene cluster for CCDC91 Gene Hs.653125

mRNA Expression by UniProt/SwissProt for CCDC91 Gene

Q7Z6B0-CCD91_HUMAN
Tissue specificity: Widely expressed.
genes like me logo Genes that share expressions with CCDC91: view

Orthologs for CCDC91 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC91 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC91 36
  • 97.1 (n)
  • 95.64 (a)
CCDC91 37
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC91 36
  • 92.52 (n)
  • 93.2 (a)
CCDC91 37
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC91 36
  • 94.56 (n)
  • 94.33 (a)
CCDC91 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc91 36
  • 77.4 (n)
  • 79.14 (a)
Ccdc91 16
Ccdc91 37
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC91 37
  • 64 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC91 37
  • 53 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc91 36
  • 76.57 (n)
  • 78.23 (a)
chicken
(Gallus gallus)
Aves CCDC91 36
  • 69.3 (n)
  • 58.7 (a)
lizard
(Anolis carolinensis)
Reptilia CCDC91 37
  • 52 (a)
OneToOne
Species with no ortholog for CCDC91:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC91 Gene

ENSEMBL:
Gene Tree for CCDC91 (if available)
TreeFam:
Gene Tree for CCDC91 (if available)

Paralogs for CCDC91 Gene

No data available for Paralogs for CCDC91 Gene

Variants for CCDC91 Gene

Sequence variations from dbSNP and Humsavar for CCDC91 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs716687 -- 28,261,517(-) ACCTC(C/T)CTAAT intron-variant
rs786708 -- 28,420,338(-) GTGCT(A/C)AAACA intron-variant
rs786709 -- 28,411,121(-) AATTT(A/G)CCATC intron-variant
rs786710 -- 28,410,703(-) ctcta(A/C)taaaa intron-variant
rs786711 -- 28,406,330(-) AAGAC(C/T)TGTAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC91 Gene

Variant ID Type Subtype PubMed ID
esv268389 CNV Insertion 20981092
esv1402084 CNV Insertion 17803354
nsv653 CNV Loss 18451855
esv271912 CNV Insertion 20981092
nsv527047 CNV Loss 19592680
nsv469179 CNV Loss 19166990
nsv523622 CNV Gain 19592680
dgv1398n71 CNV Loss 21882294
dgv93n21 CNV Loss 19592680
esv268834 CNV Insertion 20981092
nsv469181 CNV Loss 19166990
dgv1399n71 CNV Loss 21882294
dgv190n27 CNV Loss 19166990
esv271570 CNV Insertion 20981092
nsv523992 CNV Loss 19592680
nsv898948 CNV Loss 21882294
dgv191n27 CNV Loss 19166990
nsv898949 CNV Loss 21882294
nsv521777 CNV Loss 19592680
nsv654 CNV Insertion 18451855
nsv519119 CNV Gain 19592680
nsv469188 CNV Loss 19166990
nsv516088 CNV Gain 19592680
nsv826290 CNV Loss 20364138
nsv898950 CNV Gain 21882294
nsv469189 CNV Gain 19166990

Relevant External Links for CCDC91 Gene

HapMap Linkage Disequilibrium report
CCDC91

Disorders for CCDC91 Gene

Relevant External Links for CCDC91

Genetic Association Database (GAD)
CCDC91
Human Genome Epidemiology (HuGE) Navigator
CCDC91
genes like me logo Genes that share disorders with CCDC91: view

No data available for UniProtKB/Swiss-Prot for CCDC91 Gene

Publications for CCDC91 Gene

  1. Structural basis for binding of accessory proteins by the appendage domain of GGAs. (PMID: 12858163) Collins B.M. … Owen D.J. (Nat. Struct. Biol. 2003) 3 4 23
  2. Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin. (PMID: 12808037) Lui W.W.Y. … Robinson M.S. (Mol. Biol. Cell 2003) 2 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. The trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting. (PMID: 17596511) Mardones G.A. … Bonifacino J.S. (Mol. Biol. Cell 2007) 3 23

Products for CCDC91 Gene

Sources for CCDC91 Gene

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