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Aliases for CCDC90B Gene

Aliases for CCDC90B Gene

  • Coiled-Coil Domain Containing 90B 2 3 5
  • MDS011 3
  • MDS025 3

External Ids for CCDC90B Gene

Previous GeneCards Identifiers for CCDC90B Gene

  • GC11M082651
  • GC11M082972
  • GC11M079269

Summaries for CCDC90B Gene

GeneCards Summary for CCDC90B Gene

CCDC90B (Coiled-Coil Domain Containing 90B) is a Protein Coding gene. An important paralog of this gene is MCUR1.

Gene Wiki entry for CCDC90B Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC90B Gene

Genomics for CCDC90B Gene

Regulatory Elements for CCDC90B Gene

Promoters for CCDC90B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC90B on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC90B Gene

Chromosome:
11
Start:
83,259,093 bp from pter
End:
83,286,407 bp from pter
Size:
27,315 bases
Orientation:
Minus strand

Genomic View for CCDC90B Gene

Genes around CCDC90B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC90B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC90B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC90B Gene

Proteins for CCDC90B Gene

  • Protein details for CCDC90B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9GZT6-CC90B_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 90B, mitochondrial
    Protein Accession:
    Q9GZT6
    Secondary Accessions:
    • A8K8I4
    • B3KP87
    • B4E3L2
    • Q3B781
    • Q9GZU6

    Protein attributes for CCDC90B Gene

    Size:
    254 amino acids
    Molecular mass:
    29506 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC90B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC90B Gene

Proteomics data for CCDC90B Gene at MOPED

Post-translational modifications for CCDC90B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC90B Gene

Domains & Families for CCDC90B Gene

Protein Domains for CCDC90B Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q9GZT6

UniProtKB/Swiss-Prot:

CC90B_HUMAN :
  • Belongs to the CCDC90 family.
Family:
  • Belongs to the CCDC90 family.
genes like me logo Genes that share domains with CCDC90B: view

No data available for Gene Families for CCDC90B Gene

Function for CCDC90B Gene

Phenotypes for CCDC90B Gene

genes like me logo Genes that share phenotypes with CCDC90B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC90B Gene

Localization for CCDC90B Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC90B Gene

Mitochondrion. Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC90B Gene COMPARTMENTS Subcellular localization image for CCDC90B gene
Compartment Confidence
mitochondrion 5
cytosol 1
endoplasmic reticulum 1
nucleus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for CCDC90B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IDA --
genes like me logo Genes that share ontologies with CCDC90B: view

Pathways & Interactions for CCDC90B Gene

SuperPathways for CCDC90B Gene

No Data Available

Interacting Proteins for CCDC90B Gene

Gene Ontology (GO) - Biological Process for CCDC90B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC90B Gene

Drugs & Compounds for CCDC90B Gene

No Compound Related Data Available

Transcripts for CCDC90B Gene

Unigene Clusters for CCDC90B Gene

Coiled-coil domain containing 90B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC90B Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c · 2d · 2e · 2f ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
SP1: - - - - - - - -
SP2: - - - -
SP3: - -
SP4: - - -
SP5: - - - -
SP6: - - - - - -
SP7: - - - - -
SP8: - - - -
SP9: - -
SP10: - - - - -
SP11: - - -

Relevant External Links for CCDC90B Gene

GeneLoc Exon Structure for
CCDC90B
ECgene alternative splicing isoforms for
CCDC90B

Expression for CCDC90B Gene

mRNA expression in normal human tissues for CCDC90B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CCDC90B Gene

This gene is overexpressed in Bone (8.0) and Placenta (7.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for CCDC90B Gene



SOURCE GeneReport for Unigene cluster for CCDC90B Gene Hs.368866

genes like me logo Genes that share expression patterns with CCDC90B: view

Protein tissue co-expression partners for CCDC90B Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CCDC90B Gene

Orthologs for CCDC90B Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC90B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC90B 35
  • 99.74 (n)
  • 99.21 (a)
CCDC90B 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC90B 36
  • 85 (a)
OneToOne
CCDC90B 35
  • 90.64 (n)
  • 88.09 (a)
dog
(Canis familiaris)
Mammalia CCDC90B 35
  • 88.06 (n)
  • 86.22 (a)
CCDC90B 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc90b 16
Ccdc90b 36
  • 86 (a)
OneToOne
Ccdc90b 35
  • 85.96 (n)
  • 87.01 (a)
oppossum
(Monodelphis domestica)
Mammalia CCDC90B 36
  • 67 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC90B 36
  • 81 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc90b 35
  • 85.43 (n)
  • 84.65 (a)
chicken
(Gallus gallus)
Aves CCDC90B 35
  • 78.03 (n)
  • 84.33 (a)
CCDC90B 36
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC90B 36
  • 76 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc90b 35
  • 65.48 (n)
  • 68.37 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.494 35
zebrafish
(Danio rerio)
Actinopterygii ccdc90b 36
  • 58 (a)
OneToOne
ccdc90b 35
  • 63.56 (n)
  • 61.13 (a)
Species with no ortholog for CCDC90B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC90B Gene

ENSEMBL:
Gene Tree for CCDC90B (if available)
TreeFam:
Gene Tree for CCDC90B (if available)

Paralogs for CCDC90B Gene

Paralogs for CCDC90B Gene

Pseudogenes.org Pseudogenes for CCDC90B Gene

genes like me logo Genes that share paralogs with CCDC90B: view

Variants for CCDC90B Gene

Sequence variations from dbSNP and Humsavar for CCDC90B Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
VAR_033322 -
rs496690 -- 83,260,227(+) ATGTC(A/T)CTCTC utr-variant-3-prime
rs476717 -- 83,279,235(+) GAGAT(C/T)GCGCC intron-variant
rs498013 -- 83,262,985(-) ATACC(A/C)CCAAT intron-variant
rs509233 -- 83,275,520(-) ttttt(G/T)ggaat intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC90B Gene

Variant ID Type Subtype PubMed ID
esv33531 CNV Loss 17666407

Variation tolerance for CCDC90B Gene

Residual Variation Intolerance Score: 87% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.02; 37.13% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC90B Gene

HapMap Linkage Disequilibrium report
CCDC90B
Human Gene Mutation Database (HGMD)
CCDC90B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC90B Gene

Disorders for CCDC90B Gene

Relevant External Links for CCDC90B

Genetic Association Database (GAD)
CCDC90B
Human Genome Epidemiology (HuGE) Navigator
CCDC90B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC90B

No disorders were found for CCDC90B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC90B Gene

Publications for CCDC90B Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3
  4. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for CCDC90B Gene

Sources for CCDC90B Gene

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