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Aliases for CCDC89 Gene

Aliases for CCDC89 Gene

  • Coiled-Coil Domain Containing 89 2 3
  • Bc8 Orange-Interacting Protein 4
  • BOIP 4

External Ids for CCDC89 Gene

Previous GeneCards Identifiers for CCDC89 Gene

  • GC11M085073
  • GC11M085394
  • GC11M081692

Summaries for CCDC89 Gene

GeneCards Summary for CCDC89 Gene

CCDC89 (Coiled-Coil Domain Containing 89) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC89 Gene

Genomics for CCDC89 Gene

Regulatory Elements for CCDC89 Gene

Genomic Location for CCDC89 Gene

85,683,850 bp from pter
85,686,277 bp from pter
2,428 bases
Minus strand

Genomic View for CCDC89 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC89 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC89 Gene

Proteins for CCDC89 Gene

  • Protein details for CCDC89 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 89
    Protein Accession:
    Secondary Accessions:

    Protein attributes for CCDC89 Gene

    374 amino acids
    Molecular mass:
    43809 Da
    Quaternary structure:
    • Interacts with HEY1.

neXtProt entry for CCDC89 Gene

Proteomics data for CCDC89 Gene at MOPED

Post-translational modifications for CCDC89 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC89 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for CCDC89 Gene

Domains for CCDC89 Gene

Protein Domains for CCDC89 Gene


Suggested Antigen Peptide Sequences for CCDC89 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the CCDC89 family.
  • Belongs to the CCDC89 family.
genes like me logo Genes that share domains with CCDC89: view

No data available for Gene Families for CCDC89 Gene

Function for CCDC89 Gene

Gene Ontology (GO) - Molecular Function for CCDC89 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with CCDC89: view

Phenotypes for CCDC89 Gene

GenomeRNAi human phenotypes for CCDC89:
genes like me logo Genes that share phenotypes with CCDC89: view

Animal Model Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC89

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC89 Gene

Localization for CCDC89 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC89 Gene

Cytoplasm. Nucleus. Note=Uniformly distributed within the cell, but becomes recruited to the nucleus upon binding to HEY1. {ECO:0000250}.

Subcellular locations from

Jensen Localization Image for CCDC89 Gene COMPARTMENTS Subcellular localization image for CCDC89 gene
Compartment Confidence
cytosol 3
nucleus 3

Gene Ontology (GO) - Cellular Components for CCDC89 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with CCDC89: view

Pathways for CCDC89 Gene

SuperPathways for CCDC89 Gene

No Data Available

Interacting Proteins for CCDC89 Gene

Selected Interacting proteins: Q8N998-CCD89_HUMAN for CCDC89 Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for CCDC89 Gene


No data available for Pathways by source for CCDC89 Gene

Transcripts for CCDC89 Gene

mRNA/cDNA for CCDC89 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(12) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC89 Gene

Coiled-coil domain containing 89:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC89

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC89 Gene

No ASD Table

Relevant External Links for CCDC89 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC89 Gene

mRNA expression in normal human tissues for CCDC89 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC89 Gene

This gene is overexpressed in Testis (21.9).

Protein differential expression in normal tissues for CCDC89 Gene

This gene is overexpressed in Ovary (50.8) and Colon muscle (18.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC89 Gene

SOURCE GeneReport for Unigene cluster for CCDC89 Gene Hs.376241

genes like me logo Genes that share expressions with CCDC89: view

Expression partners for CCDC89 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for CCDC89 Gene

Orthologs for CCDC89 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC89 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC89 35
  • 82.36 (n)
  • 77.01 (a)
CCDC89 36
  • 76 (a)
(Canis familiaris)
Mammalia CCDC89 35
  • 87.03 (n)
  • 82.7 (a)
CCDC89 36
  • 82 (a)
(Mus musculus)
Mammalia Ccdc89 35
  • 80.27 (n)
  • 77.84 (a)
Ccdc89 16
Ccdc89 36
  • 78 (a)
(Rattus norvegicus)
Mammalia Ccdc89 35
  • 80.54 (n)
  • 78.38 (a)
(Monodelphis domestica)
Mammalia CCDC89 36
  • 67 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC89 36
  • 59 (a)
(Gallus gallus)
Aves CCDC89 35
  • 61.65 (n)
  • 50.64 (a)
CCDC89 36
  • 48 (a)
(Anolis carolinensis)
Reptilia CCDC89 36
  • 50 (a)
African clawed frog
(Xenopus laevis)
Amphibia boip 35
(Danio rerio)
Actinopterygii zgc:172182 35
  • 53.52 (n)
  • 46.06 (a)
CCDC89 36
  • 40 (a)
Species with no ortholog for CCDC89:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC89 Gene

Gene Tree for CCDC89 (if available)
Gene Tree for CCDC89 (if available)

Paralogs for CCDC89 Gene

No data available for Paralogs for CCDC89 Gene

Variants for CCDC89 Gene

Sequence variations from dbSNP and Humsavar for CCDC89 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs290185 -- 85,684,675(-) CTTCT(A/G)TGATT utr-variant-3-prime
rs290186 -- 85,684,609(-) ACCCA(C/T)TGTAG utr-variant-3-prime
rs370385 -- 85,683,418(-) AAGAA(A/G)CATAA downstream-variant-500B
rs619018 -- 85,684,485(-) TAGCT(G/T)GGAAA utr-variant-3-prime
rs558914987 -- 85,685,147(+) AGCTC(C/T)CTGAC synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for CCDC89 Gene

Variant ID Type Subtype PubMed ID
dgv1246n71 CNV Loss 21882294
essv7704 CNV CNV 17122850
esv678 CNV CNV 17122850
essv22464 CNV CNV 17122850
nsv468768 CNV Loss 19166990

Relevant External Links for CCDC89 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC89 Gene

Disorders for CCDC89 Gene

No disorders were found for CCDC89 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CCDC89 Gene

Publications for CCDC89 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Identification of BOIP, a novel cDNA highly expressed during spermatogenesis that encodes a protein interacting with the orange domain of the hairy-related transcription factor HRT1/Hey1 in Xenopus and mouse. (PMID: 14648848) Van Wayenbergh R. … Bellefroid E.J. (Dev. Dyn. 2003) 4
  5. Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry. (PMID: 15188402) Hassel S. … Souchelnytskyi S. (Proteomics 2004) 3

Products for CCDC89 Gene

Sources for CCDC89 Gene

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