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Aliases for CCDC87 Gene

Aliases for CCDC87 Gene

  • Coiled-Coil Domain Containing 87 2 3 5

External Ids for CCDC87 Gene

Previous GeneCards Identifiers for CCDC87 Gene

  • GC11M066115
  • GC11M066357
  • GC11M062685

Summaries for CCDC87 Gene

GeneCards Summary for CCDC87 Gene

CCDC87 (Coiled-Coil Domain Containing 87) is a Protein Coding gene. GO annotations related to this gene include microtubule binding.

Additional gene information for CCDC87 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC87 Gene

Genomics for CCDC87 Gene

Regulatory Elements for CCDC87 Gene

Enhancers for CCDC87 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H066591 1.6 Ensembl ENCODE dbSUPER 0.7 -1.0 -975 4 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143 MXD4 ACTN3 ENSG00000250105 C11orf80 CCDC87 GC11P066598
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCDC87 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC87 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000040986 -117 801 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143 MXD4

Genomic Location for CCDC87 Gene

Chromosome:
11
Start:
66,590,169 bp from pter
End:
66,593,083 bp from pter
Size:
2,915 bases
Orientation:
Minus strand

Genomic View for CCDC87 Gene

Genes around CCDC87 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC87 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC87 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC87 Gene

Proteins for CCDC87 Gene

  • Protein details for CCDC87 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NVE4-CCD87_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 87
    Protein Accession:
    Q9NVE4
    Secondary Accessions:
    • Q8NE76

    Protein attributes for CCDC87 Gene

    Size:
    849 amino acids
    Molecular mass:
    96402 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC87 Gene

Post-translational modifications for CCDC87 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC87 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC87 Gene

Domains & Families for CCDC87 Gene

Gene Families for CCDC87 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC87 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CCDC87 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC87: view

No data available for UniProtKB/Swiss-Prot for CCDC87 Gene

Function for CCDC87 Gene

Phenotypes From GWAS Catalog for CCDC87 Gene

Gene Ontology (GO) - Molecular Function for CCDC87 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CCDC87: view

Phenotypes for CCDC87 Gene

GenomeRNAi human phenotypes for CCDC87:
genes like me logo Genes that share phenotypes with CCDC87: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for CCDC87
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC87 Gene

Localization for CCDC87 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC87 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CCDC87 Gene

Pathways & Interactions for CCDC87 Gene

SuperPathways for CCDC87 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC87 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC87 Gene

Drugs & Compounds for CCDC87 Gene

No Compound Related Data Available

Transcripts for CCDC87 Gene

mRNA/cDNA for CCDC87 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(30) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC87 Gene

Coiled-coil domain containing 87:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for CCDC87
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC87 Gene

No ASD Table

Relevant External Links for CCDC87 Gene

GeneLoc Exon Structure for
CCDC87
ECgene alternative splicing isoforms for
CCDC87

Expression for CCDC87 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC87 Gene

Protein differential expression in normal tissues from HIPED for CCDC87 Gene

This gene is overexpressed in Spinal cord (38.3), NK cells (7.7), and Blymphocyte (6.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CCDC87 Gene



NURSA nuclear receptor signaling pathways regulating expression of CCDC87 Gene:

CCDC87

SOURCE GeneReport for Unigene cluster for CCDC87 Gene:

Hs.121072
genes like me logo Genes that share expression patterns with CCDC87: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC87 Gene

Orthologs for CCDC87 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC87 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC87 33 34
  • 99.25 (n)
dog
(Canis familiaris)
Mammalia CCDC87 33 34
  • 80.66 (n)
cow
(Bos Taurus)
Mammalia CCDC87 33 34
  • 78.65 (n)
rat
(Rattus norvegicus)
Mammalia Ccdc87 33
  • 74.09 (n)
mouse
(Mus musculus)
Mammalia Ccdc87 33 16 34
  • 73.31 (n)
oppossum
(Monodelphis domestica)
Mammalia CCDC87 34
  • 47 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC87 34
  • 32 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100486794 33
  • 43.18 (n)
zebrafish
(Danio rerio)
Actinopterygii ccdc87 34
  • 21 (a)
OneToOne
Species where no ortholog for CCDC87 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC87 Gene

ENSEMBL:
Gene Tree for CCDC87 (if available)
TreeFam:
Gene Tree for CCDC87 (if available)

Paralogs for CCDC87 Gene

No data available for Paralogs for CCDC87 Gene

Variants for CCDC87 Gene

Sequence variations from dbSNP and Humsavar for CCDC87 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000727023 -- 66,594,179(+) CAGTT(A/G)AATCC intron-variant, upstream-variant-2KB
rs1001942552 -- 66,594,791(+) AAAAA(A/T)AAACA intron-variant, upstream-variant-2KB
rs1002857887 -- 66,592,715(+) AAGTT(C/T)GGCGG upstream-variant-2KB, reference, missense
rs1003140973 -- 66,592,929(+) GACGT(A/C)GTCCT upstream-variant-2KB, reference, synonymous-codon
rs1003191553 -- 66,593,926(+) TGTCT(C/T)GTTGT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CCDC87 Gene

Variant ID Type Subtype PubMed ID
nsv522277 CNV loss 19592680

Variation tolerance for CCDC87 Gene

Residual Variation Intolerance Score: 88.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.16; 51.65% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC87 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC87

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC87 Gene

Disorders for CCDC87 Gene

Relevant External Links for CCDC87

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC87

No disorders were found for CCDC87 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC87 Gene

Publications for CCDC87 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  3. Phospho-tyrosine dependent protein-protein interaction network. (PMID: 25814554) Grossmann A … Stelzl U (Molecular systems biology 2015) 3 60
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 60
  5. LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. (PMID: 23443559) Fogeron ML … Lange BM (Nature communications 2013) 3 60

Products for CCDC87 Gene

Sources for CCDC87 Gene

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