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Aliases for CCDC86 Gene

Aliases for CCDC86 Gene

  • Coiled-Coil Domain Containing 86 2 3
  • Cyclon 3 4 6
  • Cytokine-Induced Protein With Coiled-Coil Domain 3 4
  • Coiled-Coil Domain-Containing Protein 86 3

External Ids for CCDC86 Gene

Summaries for CCDC86 Gene

GeneCards Summary for CCDC86 Gene

CCDC86 (Coiled-Coil Domain Containing 86) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC86 Gene

Genomics for CCDC86 Gene

Genomic Location for CCDC86 Gene

Start:
60,841,956 bp from pter
End:
60,851,088 bp from pter
Size:
9,133 bases
Orientation:
Plus strand

Genomic View for CCDC86 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC86 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC86 Gene

Regulatory Elements for CCDC86 Gene

Proteins for CCDC86 Gene

  • Protein details for CCDC86 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H6F5-CCD86_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 86
    Protein Accession:
    Q9H6F5
    Secondary Accessions:
    • B4DY99

    Protein attributes for CCDC86 Gene

    Size:
    360 amino acids
    Molecular mass:
    40236 Da
    Quaternary structure:
    • Interacts with hepatitis C virus (HCV) protein NS5A.

    Alternative splice isoforms for CCDC86 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC86 Gene

Proteomics data for CCDC86 Gene at MOPED

Post-translational modifications for CCDC86 Gene

Other Protein References for CCDC86 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC86 Gene

Domains for CCDC86 Gene

Protein Domains for CCDC86 Gene

ProtoNet:
genes like me logo Genes that share domains with CCDC86: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC86 Gene

Function for CCDC86 Gene

Gene Ontology (GO) - Molecular Function for CCDC86 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 15607035
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with CCDC86: view
genes like me logo Genes that share phenotypes with CCDC86: view

Animal Models for CCDC86 Gene

MGI Knock Outs for CCDC86:

miRNA for CCDC86 Gene

miRTarBase miRNAs that target CCDC86

No data available for Molecular function , Enzyme Numbers (IUBMB) , Transcription Factor Targeting and HOMER Transcription for CCDC86 Gene

Localization for CCDC86 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC86 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC86 Gene COMPARTMENTS Subcellular localization image for CCDC86 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for CCDC86 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005654 nucleoplasm IDA --
GO:0005730 nucleolus IDA --
genes like me logo Genes that share ontologies with CCDC86: view

Pathways for CCDC86 Gene

SuperPathways for CCDC86 Gene

No Data Available

Interacting Proteins for CCDC86 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000227520%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000329466%0d%0a
Selected Interacting proteins: Q9H6F5-CCD86_HUMAN ENSP00000227520 for CCDC86 Gene via MINT STRING UniProtKB I2D

Gene Ontology (GO) - Biological Process for CCDC86 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016032 viral process IEA --
genes like me logo Genes that share ontologies with CCDC86: view

No data available for Pathways by source for CCDC86 Gene

Transcripts for CCDC86 Gene

mRNA/cDNA for CCDC86 Gene

Unigene Clusters for CCDC86 Gene

Coiled-coil domain containing 86:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC86 Gene

No ASD Table

Relevant External Links for CCDC86 Gene

GeneLoc Exon Structure for
CCDC86
ECgene alternative splicing isoforms for
CCDC86

Expression for CCDC86 Gene

mRNA expression in normal human tissues for CCDC86 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CCDC86 Gene

SOURCE GeneReport for Unigene cluster for CCDC86 Gene Hs.4253

genes like me logo Genes that share expressions with CCDC86: view

Orthologs for CCDC86 Gene

This gene was present in the common ancestor of animals.

Orthologs for CCDC86 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC86 36
  • 98.98 (n)
  • 98.89 (a)
CCDC86 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 76 (a)
OneToMany
-- 37
  • 63 (a)
OneToMany
CCDC86 36
  • 83.62 (n)
  • 76.84 (a)
dog
(Canis familiaris)
Mammalia CCDC86 37
  • 66 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc86 36
  • 77.4 (n)
  • 74.5 (a)
Ccdc86 16
Ccdc86 37
  • 59 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC86 37
  • 50 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc86 36
  • 77.97 (n)
  • 73.45 (a)
chicken
(Gallus gallus)
Aves CCDC86 37
  • 37 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC86 37
  • 67 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733466 36
  • 65.61 (n)
  • 71.58 (a)
Str.10541 36
zebrafish
(Danio rerio)
Actinopterygii CCDC86 37
  • 35 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG14210 37
  • 44 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y40B1B.7 37
  • 42 (a)
OneToOne
Species with no ortholog for CCDC86:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CCDC86 Gene

ENSEMBL:
Gene Tree for CCDC86 (if available)
TreeFam:
Gene Tree for CCDC86 (if available)

Paralogs for CCDC86 Gene

Pseudogenes.org Pseudogenes for CCDC86 Gene

genes like me logo Genes that share paralogs with CCDC86: view

No data available for Paralogs for CCDC86 Gene

Variants for CCDC86 Gene

Sequence variations from dbSNP and Humsavar for CCDC86 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs478886 -- 60,846,874(-) AAGAT(C/T)agccg intron-variant
rs480081 -- 60,848,441(-) ATGGA(G/T)TTCAA intron-variant
rs488731 -- 60,844,362(-) TGCAT(A/G)CTCTG intron-variant
rs495949 -- 60,850,173(-) AGTGC(A/G)GCTGC intron-variant
rs500595 -- 60,849,685(+) CTCAG(C/T)CCCTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC86 Gene

Variant ID Type Subtype PubMed ID
nsv897598 CNV Loss 21882294

Relevant External Links for CCDC86 Gene

HapMap Linkage Disequilibrium report
CCDC86

Disorders for CCDC86 Gene

Relevant External Links for CCDC86

Genetic Association Database (GAD)
CCDC86
Human Genome Epidemiology (HuGE) Navigator
CCDC86
genes like me logo Genes that share disorders with CCDC86: view

No data available for UniProtKB/Swiss-Prot for CCDC86 Gene

Publications for CCDC86 Gene

  1. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PMID: 20198315) Yoshida T. … Yamada Y. (Int. J. Mol. Med. 2010) 3 49
  2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 49
  3. Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus. (PMID: 15607035) Ahn J. … Hoe K.-L. (J. Biochem. Mol. Biol. 2004) 3 4
  4. Redundant promoter elements mediate IL-3-induced expression of a novel cytokine-inducible gene, cyclon. (PMID: 17300783) Hoshino A. … Fujii H. (FEBS Lett. 2007) 3 4
  5. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PMID: 19851296) Oguri M. … Yamada Y. (Am. J. Hypertens. 2010) 3 49

Products for CCDC86 Gene

Sources for CCDC86 Gene

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