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Aliases for CCDC85A Gene

Aliases for CCDC85A Gene

  • Coiled-Coil Domain Containing 85A 2 3
  • KIAA1912 4

External Ids for CCDC85A Gene

Summaries for CCDC85A Gene

GeneCards Summary for CCDC85A Gene

CCDC85A (Coiled-Coil Domain Containing 85A) is a Protein Coding gene. An important paralog of this gene is CCDC85C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC85A Gene

Genomics for CCDC85A Gene

Genomic Location for CCDC85A Gene

Start:
56,184,123 bp from pter
End:
56,386,174 bp from pter
Size:
202,052 bases
Orientation:
Plus strand

Genomic View for CCDC85A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC85A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC85A Gene

Regulatory Elements for CCDC85A Gene

Proteins for CCDC85A Gene

  • Protein details for CCDC85A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96PX6-CC85A_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 85A
    Protein Accession:
    Q96PX6
    Secondary Accessions:

    Protein attributes for CCDC85A Gene

    Size:
    553 amino acids
    Molecular mass:
    59976 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB67805.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for CCDC85A Gene

Proteomics data for CCDC85A Gene at MOPED

Post-translational modifications for CCDC85A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC85A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC85A Gene

Domains for CCDC85A Gene

Protein Domains for CCDC85A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

CC85A_HUMAN
Family:
  • Belongs to the CCDC85 family.:
    • Q96PX6
genes like me logo Genes that share domains with CCDC85A: view

No data available for Gene Families for CCDC85A Gene

Function for CCDC85A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC85A Gene

Localization for CCDC85A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC85A Gene COMPARTMENTS Subcellular localization image for CCDC85A gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1

No data available for Gene Ontology (GO) - Cellular Components for CCDC85A Gene

Pathways for CCDC85A Gene

SuperPathways for CCDC85A Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC85A Gene

None

No data available for Pathways by source for CCDC85A Gene

Transcripts for CCDC85A Gene

mRNA/cDNA for CCDC85A Gene

(2) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(41) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC85A Gene

Coiled-coil domain containing 85A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC85A Gene

No ASD Table

Relevant External Links for CCDC85A Gene

GeneLoc Exon Structure for
CCDC85A
ECgene alternative splicing isoforms for
CCDC85A

Expression for CCDC85A Gene

mRNA expression in normal human tissues for CCDC85A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC85A Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (6.0) and Brain - Anterior cingulate cortex (BA24) (5.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CCDC85A Gene

SOURCE GeneReport for Unigene cluster for CCDC85A Gene Hs.117136

genes like me logo Genes that share expressions with CCDC85A: view

Orthologs for CCDC85A Gene

This gene was present in the common ancestor of animals.

Orthologs for CCDC85A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC85A 36
  • 98.73 (n)
  • 98.73 (a)
CCDC85A 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC85A 37
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC85A 36
  • 92.36 (n)
  • 94.22 (a)
CCDC85A 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc85a 36
  • 88.59 (n)
  • 92.62 (a)
Ccdc85a 16
Ccdc85a 37
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC85A 37
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC85A 37
  • 75 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc85a 36
  • 88.56 (n)
  • 93.81 (a)
chicken
(Gallus gallus)
Aves CCDC85A 36
  • 77.92 (n)
  • 80.25 (a)
CCDC85A 37
  • 74 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC85A 37
  • 76 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ccdc85a 37
  • 51 (a)
OneToMany
ccdc85al 37
  • 46 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG17265 37
  • 17 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F29G9.2 37
  • 18 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4851 37
  • 45 (a)
OneToMany
Species with no ortholog for CCDC85A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for CCDC85A Gene

ENSEMBL:
Gene Tree for CCDC85A (if available)
TreeFam:
Gene Tree for CCDC85A (if available)

Paralogs for CCDC85A Gene

Paralogs for CCDC85A Gene

Selected SIMAP similar genes for CCDC85A Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for CCDC85A Gene

genes like me logo Genes that share paralogs with CCDC85A: view

Variants for CCDC85A Gene

Sequence variations from dbSNP and Humsavar for CCDC85A Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs214035 -- 56,313,797(-) CCCCT(A/G)TTCCT intron-variant
rs214036 -- 56,311,645(-) TCTCA(A/C)CAAAT intron-variant
rs214037 -- 56,310,262(-) CTTCT(C/T)CCTTG intron-variant
rs214038 -- 56,297,199(-) CCTCT(A/G)ATCAT intron-variant
rs214039 -- 56,288,371(-) ATTCC(C/T)GGTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC85A Gene

Variant ID Type Subtype PubMed ID
dgv1186e1 CNV Complex 17122850
nsv874162 CNV Gain 21882294
nsv874169 CNV Loss 21882294
nsv829431 CNV Gain 20364138
esv2669305 CNV Deletion 23128226
esv2720094 CNV Deletion 23290073
esv2211763 CNV Deletion 18987734
esv2720096 CNV Deletion 23290073
nsv522006 CNV Loss 19592680
nsv874170 CNV Gain 21882294
esv2663248 CNV Deletion 23128226
nsv834093 CNV Gain 17160897
nsv874171 CNV Gain 21882294
nsv522944 CNV Gain 19592680

Relevant External Links for CCDC85A Gene

HapMap Linkage Disequilibrium report
CCDC85A

Disorders for CCDC85A Gene

Relevant External Links for CCDC85A

Genetic Association Database (GAD)
CCDC85A
Human Genome Epidemiology (HuGE) Navigator
CCDC85A
genes like me logo Genes that share disorders with CCDC85A: view

No data available for UniProtKB/Swiss-Prot for CCDC85A Gene

Publications for CCDC85A Gene

  1. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PMID: 11572484) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  3. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. (PMID: 21102462) Elks C.E. … Murray A. (Nat. Genet. 2010) 3 49
  4. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3
  5. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PMID: 17903294) Yang Q. … O'Donnell C.J. (BMC Med. Genet. 2007) 49

Products for CCDC85A Gene

Sources for CCDC85A Gene

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