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Aliases for CCDC85A Gene

Aliases for CCDC85A Gene

  • Coiled-Coil Domain Containing 85A 2 3
  • KIAA1912 4

External Ids for CCDC85A Gene

Previous GeneCards Identifiers for CCDC85A Gene

  • GC02P056264
  • GC02P056411
  • GC02P056146

Summaries for CCDC85A Gene

GeneCards Summary for CCDC85A Gene

CCDC85A (Coiled-Coil Domain Containing 85A) is a Protein Coding gene. An important paralog of this gene is CCDC85C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC85A Gene

Genomics for CCDC85A Gene

Regulatory Elements for CCDC85A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CCDC85A Gene

56,184,123 bp from pter
56,386,174 bp from pter
202,052 bases
Plus strand

Genomic View for CCDC85A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC85A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC85A Gene

Proteins for CCDC85A Gene

  • Protein details for CCDC85A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 85A
    Protein Accession:
    Secondary Accessions:

    Protein attributes for CCDC85A Gene

    553 amino acids
    Molecular mass:
    59976 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB67805.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for CCDC85A Gene

Proteomics data for CCDC85A Gene at MOPED

Post-translational modifications for CCDC85A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC85A Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for CCDC85A Gene

Domains for CCDC85A Gene

Protein Domains for CCDC85A Gene


Suggested Antigen Peptide Sequences for CCDC85A Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the CCDC85 family.
  • Belongs to the CCDC85 family.
genes like me logo Genes that share domains with CCDC85A: view

No data available for Gene Families for CCDC85A Gene

Function for CCDC85A Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC85A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC85A Gene

Localization for CCDC85A Gene

Subcellular locations from

Jensen Localization Image for CCDC85A Gene COMPARTMENTS Subcellular localization image for CCDC85A gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC85A Gene

Pathways for CCDC85A Gene

SuperPathways for CCDC85A Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC85A Gene


No data available for Pathways by source for CCDC85A Gene

Transcripts for CCDC85A Gene

mRNA/cDNA for CCDC85A Gene

(2) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(41) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC85A Gene

Coiled-coil domain containing 85A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC85A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC85A Gene

No ASD Table

Relevant External Links for CCDC85A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC85A Gene

mRNA expression in normal human tissues for CCDC85A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC85A Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (6.0) and Brain - Anterior cingulate cortex (BA24) (5.4).

Protein differential expression in normal tissues for CCDC85A Gene

This gene is overexpressed in Frontal cortex (60.2) and Fetal Brain (8.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CCDC85A Gene

SOURCE GeneReport for Unigene cluster for CCDC85A Gene Hs.117136

genes like me logo Genes that share expressions with CCDC85A: view

Expression partners for CCDC85A Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for CCDC85A Gene

Orthologs for CCDC85A Gene

This gene was present in the common ancestor of animals.

Orthologs for CCDC85A Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia CCDC85A 35
  • 92.36 (n)
  • 94.22 (a)
CCDC85A 36
  • 94 (a)
(Mus musculus)
Mammalia Ccdc85a 35
  • 88.59 (n)
  • 92.62 (a)
Ccdc85a 16
Ccdc85a 36
  • 91 (a)
(Pan troglodytes)
Mammalia CCDC85A 35
  • 98.73 (n)
  • 98.73 (a)
CCDC85A 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ccdc85a 35
  • 88.56 (n)
  • 93.81 (a)
(Bos Taurus)
Mammalia CCDC85A 36
  • 86 (a)
(Monodelphis domestica)
Mammalia CCDC85A 36
  • 82 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC85A 36
  • 75 (a)
(Gallus gallus)
Aves CCDC85A 35
  • 77.92 (n)
  • 80.25 (a)
CCDC85A 36
  • 74 (a)
(Anolis carolinensis)
Reptilia CCDC85A 36
  • 76 (a)
(Danio rerio)
Actinopterygii ccdc85a 36
  • 51 (a)
ccdc85al 36
  • 46 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG17265 36
  • 17 (a)
(Caenorhabditis elegans)
Secernentea F29G9.2 36
  • 18 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4851 36
  • 45 (a)
Species with no ortholog for CCDC85A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for CCDC85A Gene

Gene Tree for CCDC85A (if available)
Gene Tree for CCDC85A (if available)

Paralogs for CCDC85A Gene

Paralogs for CCDC85A Gene

(2) SIMAP similar genes for CCDC85A Gene using alignment to 2 proteins: Pseudogenes for CCDC85A Gene

genes like me logo Genes that share paralogs with CCDC85A: view

Variants for CCDC85A Gene

Sequence variations from dbSNP and Humsavar for CCDC85A Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs214035 -- 56,313,797(-) CCCCT(A/G)TTCCT intron-variant
rs214036 -- 56,311,645(-) TCTCA(A/C)CAAAT intron-variant
rs214037 -- 56,310,262(-) CTTCT(C/T)CCTTG intron-variant
rs214038 -- 56,297,199(-) CCTCT(A/G)ATCAT intron-variant
rs214039 -- 56,288,371(-) ATTCC(C/T)GGTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC85A Gene

Variant ID Type Subtype PubMed ID
dgv1186e1 CNV Complex 17122850
nsv874162 CNV Gain 21882294
nsv874169 CNV Loss 21882294
nsv829431 CNV Gain 20364138
esv2669305 CNV Deletion 23128226
esv2720094 CNV Deletion 23290073
esv2211763 CNV Deletion 18987734
esv2720096 CNV Deletion 23290073
nsv522006 CNV Loss 19592680
nsv874170 CNV Gain 21882294
esv2663248 CNV Deletion 23128226
nsv834093 CNV Gain 17160897
nsv874171 CNV Gain 21882294
nsv522944 CNV Gain 19592680

Relevant External Links for CCDC85A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC85A Gene

Disorders for CCDC85A Gene

Relevant External Links for CCDC85A

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for CCDC85A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for CCDC85A Gene

Publications for CCDC85A Gene

  1. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PMID: 11572484) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  3. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. (PMID: 21102462) Elks C.E. … Murray A. (Nat. Genet. 2010) 3 48
  4. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3
  5. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PMID: 17903294) Yang Q. … O'Donnell C.J. (BMC Med. Genet. 2007) 48

Products for CCDC85A Gene

Sources for CCDC85A Gene

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