CCDC84 Gene
protein-coding GIFtS: 37
GCID: GC11P118868
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coiled-coil domain containing 84
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Aliases
for CCDC84 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Coiled-Coil Domain Containing 841 2 | | DLNB141 | | Coiled-Coil Domain-Containing Protein 842 |
Export aliases for CCDC84 gene to outside databasesPrevious GC identifers: GC11P118377 GC11P114808 |
Summaries
for CCDC84 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCDC84 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCDC84 gene promoter:
E2F-3a E2F-4 E2F-5 RP58 AML1a E2F-2 Roaz HEN1 E2F-1 E2F
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC84
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC84 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q23.3 Ensembl cytogenetic band: 11q23.3 HGNC cytogenetic band: 11q23.3CCDC84 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P118868: view genomic region
(about GC identifiers)
Start:
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118,868,852 bp from pter |
End:
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118,886,501 bp from pter |
Size:
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17,650 bases |
Orientation:
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plus strand |
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Proteins
for CCDC84 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CCD84_HUMAN, Q86UT8 (See
protein sequence)Recommended Name: Coiled-coil domain-containing protein 84 Size: 332 amino acids; 37974 DaExplore the universe of human proteins at neXtProt for CCDC84: NX_Q86UT8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86UT8
CCDC84 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_940891.1
ENSEMBL proteins: ENSP00000334767 ENSP00000436340 ENSP00000431889
Human Recombinant Protein Products:
CCDC84 Antibody Products:
Assay Products for CCDC84: |
Protein
Domains /
Families
for CCDC84 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q86UT8 |
Function
for CCDC84 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC84 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC84
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CCDC84 (NM_198489) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC84 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC84 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC84 |
|
Pathways & Interactions
for CCDC84 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC84
|
Drugs & Compounds
for CCDC84 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCDC84
Search CenterWatch for drugs/clinical trials and news about CCDC84 / CCD84
|
Transcripts
for CCDC84 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCDC84 gene: NM_198489.1 Unigene Cluster for CCDC84: Coiled-coil domain containing 84 Hs.534613 [show with all ESTs]Unigene Representative Sequence: BC14420810 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000334418(uc001pul.3 uc010ryk.2 uc010ryl.2) ENST00000524670
ENST00000526463(uc010rym.2) ENST00000532132 ENST00000534656 ENST00000580556
ENST00000528088 ENST00000583842 ENST00000527356 ENST00000533787
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC84 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC84
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CCDC84 (NM_198489) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC84 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC84 |
Additional cDNA sequence: AB094093.1 BC126469.1 BC126471.1 BC144208.1 BC144209.1 BC144210.1 17 DOTS entries: DT.95272257 DT.87016238 DT.100795737 DT.91747087 DT.120718661 DT.91804642 DT.95232829 DT.100795734 DT.120718651 DT.301568 DT.100036000 DT.91747085 DT.100795736 DT.99940039 DT.92383658 DT.120718579 DT.91861985 24/116 AceView cDNA sequences (see all 116): BQ007036 BU733404 BM929870 BX281470 AI697110 AI678463 BU608895 AI270685 BU608980 AI696295 BM975657 BG149789 CD171823 BM972124 BM729072 BF109076 BE796421 CA438335 NM_198489 CB241703 CA438500 BE644916 AI887619 BM684305
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for CCDC84 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 |
|---|
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| SP1: | | | | | | | | | - | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CCDC84
|
Expression
for CCDC84 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCDC84 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGCTAAAAG
About this image
See CCDC84 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCDC84
SOURCE GeneReport for Unigene cluster: Hs.534613
SABiosciences Custom PCR Arrays for CCDC84
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC84
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CCDC84 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC84 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC84 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC84 |
Orthologs
for CCDC84 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CCDC84 gene from 7/16 species (see all 16) About this table
ENSEMBL Gene Tree for CCDC84 (if available)
TreeFam Gene Tree for CCDC84 (if available) |
Paralogs
for CCDC84 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CCDC84 gene
CCDC84 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CCDC84
PGOHUM00000247446
|
Genomic Variants
for CCDC84 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCDC84 (118868852 - 118886501 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CCDC84
1 CNV: 39090 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC84 |
|
Disorders
/ Diseases
for CCDC84 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for CCDC84 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCDC84 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CCDC84) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
|
External Searches for CCDC84 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCDC84 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC84 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCDC84 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCDC84 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CCDC84 gene:
Search GeneIP for patents involving CCDC84
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC84 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CCDC84 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCDC84 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC84 | | | OriGene Protein Over-expression Lysate for CCDC84 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCDC84 | | OriGene 3'-UTR Clone for CCDC84 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC84 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC84 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCDC84 | | OriGene Custom Protein Services for CCDC84 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC84 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC84 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC84 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCDC84 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC84 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC84 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for CCDC84 |
| |  |  |  |  | | | | |
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 | | | CCDC84 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC84 |
|  |  |  | | | | Search ThermoFisher Antibodies for CCDC84 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC84 |
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