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Aliases for CCDC83 Gene

Aliases for CCDC83 Gene

  • Coiled-Coil Domain Containing 83 2 3 5
  • CT148 3
  • HSD9 3

External Ids for CCDC83 Gene

Previous GeneCards Identifiers for CCDC83 Gene

  • GC11P085244
  • GC11P085566
  • GC11P081863

Summaries for CCDC83 Gene

GeneCards Summary for CCDC83 Gene

CCDC83 (Coiled-Coil Domain Containing 83) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC83 Gene

Genomics for CCDC83 Gene

Regulatory Elements for CCDC83 Gene

Promoters for CCDC83 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC83 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC83 Gene

Chromosome:
11
Start:
85,855,055 bp from pter
End:
85,920,021 bp from pter
Size:
64,967 bases
Orientation:
Plus strand

Genomic View for CCDC83 Gene

Genes around CCDC83 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC83 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC83 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC83 Gene

Proteins for CCDC83 Gene

  • Protein details for CCDC83 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IWF9-CCD83_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 83
    Protein Accession:
    Q8IWF9
    Secondary Accessions:
    • B2RA49
    • Q6X7T2
    • Q6ZVT5
    • Q8N9Y1

    Protein attributes for CCDC83 Gene

    Size:
    413 amino acids
    Molecular mass:
    48851 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04154.1; Type=Frameshift; Positions=225; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC83 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC83 Gene

Proteomics data for CCDC83 Gene at MOPED

Post-translational modifications for CCDC83 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC83 Gene

Antibody Products

No data available for DME Specific Peptides for CCDC83 Gene

Domains & Families for CCDC83 Gene

Protein Domains for CCDC83 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC83 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC83: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC83 Gene

Function for CCDC83 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC83 Gene

Localization for CCDC83 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC83 Gene COMPARTMENTS Subcellular localization image for CCDC83 gene
Compartment Confidence
cytosol 3
nucleus 3
mitochondrion 2
peroxisome 2
plasma membrane 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC83 Gene

Pathways & Interactions for CCDC83 Gene

SuperPathways for CCDC83 Gene

No Data Available

Interacting Proteins for CCDC83 Gene

Gene Ontology (GO) - Biological Process for CCDC83 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC83 Gene

Drugs & Compounds for CCDC83 Gene

No Compound Related Data Available

Transcripts for CCDC83 Gene

Unigene Clusters for CCDC83 Gene

Coiled-coil domain containing 83:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC83 Gene

No ASD Table

Relevant External Links for CCDC83 Gene

GeneLoc Exon Structure for
CCDC83
ECgene alternative splicing isoforms for
CCDC83

Expression for CCDC83 Gene

mRNA expression in normal human tissues for CCDC83 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC83 Gene

This gene is overexpressed in Testis (x52.2).

Protein differential expression in normal tissues from HIPED for CCDC83 Gene

This gene is overexpressed in Gallbladder (43.0), Breast (16.5), and Heart (9.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC83 Gene



SOURCE GeneReport for Unigene cluster for CCDC83 Gene Hs.567774

genes like me logo Genes that share expression patterns with CCDC83: view

Protein tissue co-expression partners for CCDC83 Gene

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for CCDC83 Gene

Orthologs for CCDC83 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC83 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC83 35
  • 99.35 (n)
  • 98.55 (a)
CCDC83 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC83 36
  • 59 (a)
OneToOne
CCDC83 35
  • 86.37 (n)
  • 79.32 (a)
dog
(Canis familiaris)
Mammalia CCDC83 35
  • 85.89 (n)
  • 79.56 (a)
CCDC83 36
  • 79 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc83 16
Ccdc83 35
  • 75.59 (n)
  • 64.62 (a)
Ccdc83 36
  • 64 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC83 36
  • 53 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC83 36
  • 45 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc83 35
  • 76.69 (n)
  • 67.91 (a)
chicken
(Gallus gallus)
Aves CCDC83 35
  • 56.67 (n)
  • 37.63 (a)
CCDC83 36
  • 35 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC83 36
  • 44 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc83 35
  • 50.76 (n)
  • 37.56 (a)
zebrafish
(Danio rerio)
Actinopterygii ccdc83 36
  • 21 (a)
OneToOne
ccdc83 35
  • 43.31 (n)
  • 25.58 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10447 36
  • 29 (a)
OneToOne
Species with no ortholog for CCDC83:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC83 Gene

ENSEMBL:
Gene Tree for CCDC83 (if available)
TreeFam:
Gene Tree for CCDC83 (if available)

Paralogs for CCDC83 Gene

No data available for Paralogs for CCDC83 Gene

Variants for CCDC83 Gene

Sequence variations from dbSNP and Humsavar for CCDC83 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs12362209 - 85,873,260(+) TAAAG(A/G)CACTT reference, missense
rs725459 -- 85,899,066(+) TTTAA(C/G)TGGAA intron-variant
rs1445496 -- 85,913,935(+) CTAGC(A/G)ATTAA intron-variant
rs1445502 -- 85,878,255(-) GTTAA(A/T)CTTGT intron-variant, upstream-variant-2KB
rs1445503 -- 85,873,968(-) GAAGC(C/T)AAAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC83 Gene

Variant ID Type Subtype PubMed ID
esv678 CNV CNV 17122850
essv22464 CNV CNV 17122850
nsv832222 CNV Gain 17160897
nsv898051 CNV Loss 21882294
dgv1247n71 CNV Loss 21882294
nsv418 CNV Insertion 18451855
esv2744853 CNV Deletion 23290073
esv2678670 CNV Deletion 23128226

Variation tolerance for CCDC83 Gene

Residual Variation Intolerance Score: 81.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.16; 75.79% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC83 Gene

HapMap Linkage Disequilibrium report
CCDC83

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC83 Gene

Disorders for CCDC83 Gene

Relevant External Links for CCDC83

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC83

No disorders were found for CCDC83 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC83 Gene

Publications for CCDC83 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. KP-CoT-23 (CCDC83) is a novel immunogenic cancer/testis antigen in colon cancer. (PMID: 22923163) Song M.H. … Lee S.Y. (Int. J. Oncol. 2012) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. [Characteristics of a novel human testis-specific gene, HSD-9, and its encoding protein]. (PMID: 17633455) Wang Y. … Wang L.F. (Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2007) 3

Products for CCDC83 Gene

Sources for CCDC83 Gene

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