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Aliases for CCDC82 Gene

Aliases for CCDC82 Gene

  • Coiled-Coil Domain Containing 82 2 3 5
  • Coiled-Coil Domain-Containing Protein 82 3
  • HSPC048 3

External Ids for CCDC82 Gene

Previous GeneCards Identifiers for CCDC82 Gene

  • GC11M095726
  • GC11M096085
  • GC11M092152

Summaries for CCDC82 Gene

GeneCards Summary for CCDC82 Gene

CCDC82 (Coiled-Coil Domain Containing 82) is a Protein Coding gene.

Additional gene information for CCDC82 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC82 Gene

Genomics for CCDC82 Gene

Regulatory Elements for CCDC82 Gene

Enhancers for CCDC82 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H096388 1.1 ENCODE 83.4 +0.1 80 2 HDGF PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143 CCDC82 MAML2
GH11H096318 0.9 dbSUPER 47.5 +70.8 70845 0 HDAC1 ARNT TCF12 GATA2 EGR1 ZBTB2 ZBTB11 ZEB2 ZNF592 NFIC CCDC82 MAML2 GC11M096338 GC11P096202
GH11H096305 1.9 FANTOM5 Ensembl ENCODE dbSUPER 18.4 +79.2 79230 10 PKNOX1 ATF1 FEZF1 ZNF2 TCF12 GATA2 FOS MAFF SMARCA4 STAT3 CCDC82 MAML2 GC11M096338 GC11P096202
GH11H096153 1.9 FANTOM5 Ensembl ENCODE dbSUPER 13.2 +233.8 233843 5 HDGF PKNOX1 ATF1 ZFP64 SIN3A ZNF766 GATA2 FOS RUNX3 SP5 FAM76B CEP57 CCDC82 FGFR3P2 JRKL MAML2 GC11P096202 GC11M095989
GH11H096328 1.5 Ensembl ENCODE dbSUPER 15.3 +58.7 58714 5 PKNOX1 FOXA2 ARNT FEZF1 TCF12 ZNF766 GATA2 CAVIN1 ZNF592 MEF2D FGFR3P2 FAM76B CCDC82 CEP57 JRKL MAML2 GC11M096338 GC11P096202
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CCDC82 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC82 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000043765 131 2001 HDGF PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 ZNF207

Genomic Location for CCDC82 Gene

Chromosome:
11
Start:
96,352,765 bp from pter
End:
96,389,931 bp from pter
Size:
37,167 bases
Orientation:
Minus strand

Genomic View for CCDC82 Gene

Genes around CCDC82 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC82 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC82 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC82 Gene

Proteins for CCDC82 Gene

  • Protein details for CCDC82 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N4S0-CCD82_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 82
    Protein Accession:
    Q8N4S0
    Secondary Accessions:
    • B3KPU7
    • Q8WV71
    • Q9H2Q5
    • Q9H5E3

    Protein attributes for CCDC82 Gene

    Size:
    544 amino acids
    Molecular mass:
    64002 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB15683.1; Type=Frameshift; Positions=527; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC82 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC82 Gene

Post-translational modifications for CCDC82 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CCDC82 Gene

Domains & Families for CCDC82 Gene

Gene Families for CCDC82 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CCDC82 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC82 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC82: view

No data available for UniProtKB/Swiss-Prot for CCDC82 Gene

Function for CCDC82 Gene

Phenotypes From GWAS Catalog for CCDC82 Gene

Phenotypes for CCDC82 Gene

genes like me logo Genes that share phenotypes with CCDC82: view

Animal Model Products

CRISPR Products

miRNA for CCDC82 Gene

miRTarBase miRNAs that target CCDC82

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for CCDC82
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC82 Gene

Localization for CCDC82 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CCDC82 gene
Compartment Confidence
nucleus 4
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleus (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC82 Gene

Pathways & Interactions for CCDC82 Gene

SuperPathways for CCDC82 Gene

No Data Available

Interacting Proteins for CCDC82 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000278520%0d%0a9606.ENSP00000455169%0d%0a9606.ENSP00000354681%0d%0a
Selected Interacting proteins: ENSP00000278520 Q8N4S0-CCD82_HUMAN for CCDC82 Gene via STRING IID

Gene Ontology (GO) - Biological Process for CCDC82 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC82 Gene

Drugs & Compounds for CCDC82 Gene

No Compound Related Data Available

Transcripts for CCDC82 Gene

Unigene Clusters for CCDC82 Gene

Coiled-coil domain containing 82:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for CCDC82
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC82 Gene

No ASD Table

Relevant External Links for CCDC82 Gene

GeneLoc Exon Structure for
CCDC82
ECgene alternative splicing isoforms for
CCDC82

Expression for CCDC82 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CCDC82 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CCDC82 Gene

This gene is overexpressed in Kidney (53.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CCDC82 Gene



Protein tissue co-expression partners for CCDC82 Gene

NURSA nuclear receptor signaling pathways regulating expression of CCDC82 Gene:

CCDC82

SOURCE GeneReport for Unigene cluster for CCDC82 Gene:

Hs.525088

Evidence on tissue expression from TISSUES for CCDC82 Gene

  • Nervous system(2.8)
  • Pancreas(2.3)
genes like me logo Genes that share expression patterns with CCDC82: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CCDC82 Gene

Orthologs for CCDC82 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC82 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC82 33 34
  • 99.45 (n)
dog
(Canis familiaris)
Mammalia CCDC82 33 34
  • 89.21 (n)
cow
(Bos Taurus)
Mammalia CCDC82 33 34
  • 86.09 (n)
mouse
(Mus musculus)
Mammalia Ccdc82 33 16 34
  • 80.62 (n)
rat
(Rattus norvegicus)
Mammalia Ccdc82 33
  • 79.96 (n)
oppossum
(Monodelphis domestica)
Mammalia CCDC82 34
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC82 34
  • 48 (a)
OneToOne
chicken
(Gallus gallus)
Aves CCDC82 33 34
  • 57.96 (n)
lizard
(Anolis carolinensis)
Reptilia CCDC82 34
  • 39 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc82 33
  • 54.92 (n)
zebrafish
(Danio rerio)
Actinopterygii ccdc82 34
  • 32 (a)
OneToOne
Species where no ortholog for CCDC82 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC82 Gene

ENSEMBL:
Gene Tree for CCDC82 (if available)
TreeFam:
Gene Tree for CCDC82 (if available)

Paralogs for CCDC82 Gene

No data available for Paralogs for CCDC82 Gene

Variants for CCDC82 Gene

Sequence variations from dbSNP and Humsavar for CCDC82 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000079965 -- 96,365,614(+) ATCCT(C/T)CTATG intron-variant
rs1000084043 -- 96,373,671(+) CCAAA(C/G)TGTCT intron-variant
rs1000124578 -- 96,368,711(+) AATAC(A/G/T)AAAAA intron-variant
rs1000439490 -- 96,363,052(+) CTGCC(C/T)GCCGG intron-variant
rs1000491223 -- 96,356,227(+) CTTTG(A/C)GAAAC intron-variant, utr-variant-3-prime

Variation tolerance for CCDC82 Gene

Residual Variation Intolerance Score: 74.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.02; 87.46% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC82 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC82

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCDC82 Gene

Disorders for CCDC82 Gene

Relevant External Links for CCDC82

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC82

No disorders were found for CCDC82 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC82 Gene

Publications for CCDC82 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  4. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PMID: 10931946) Hu RM … Chen JL (Proceedings of the National Academy of Sciences of the United States of America 2000) 3 4 60
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60

Products for CCDC82 Gene

Sources for CCDC82 Gene

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