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Aliases for CCDC81 Gene

Aliases for CCDC81 Gene

  • Coiled-Coil Domain Containing 81 2 3

External Ids for CCDC81 Gene

Previous GeneCards Identifiers for CCDC81 Gene

  • GC11P085764
  • GC11P086085
  • GC11P082374

Summaries for CCDC81 Gene

GeneCards Summary for CCDC81 Gene

CCDC81 (Coiled-Coil Domain Containing 81) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC81 Gene

Genomics for CCDC81 Gene

Regulatory Elements for CCDC81 Gene

Genomic Location for CCDC81 Gene

86,374,736 bp from pter
86,423,109 bp from pter
48,374 bases
Plus strand

Genomic View for CCDC81 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC81 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC81 Gene

Proteins for CCDC81 Gene

  • Protein details for CCDC81 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 81
    Protein Accession:
    Secondary Accessions:
    • A0AVL7
    • Q53FW3
    • Q9H5E5

    Protein attributes for CCDC81 Gene

    652 amino acids
    Molecular mass:
    76084 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAD96888.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC81 Gene


neXtProt entry for CCDC81 Gene

Proteomics data for CCDC81 Gene at MOPED

Post-translational modifications for CCDC81 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC81 Gene

No data available for DME Specific Peptides for CCDC81 Gene

Domains for CCDC81 Gene

Protein Domains for CCDC81 Gene

Suggested Antigen Peptide Sequences for CCDC81 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC81: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC81 Gene

Function for CCDC81 Gene

Gene Ontology (GO) - Molecular Function for CCDC81 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding --
genes like me logo Genes that share ontologies with CCDC81: view

Phenotypes for CCDC81 Gene

GenomeRNAi human phenotypes for CCDC81:
genes like me logo Genes that share phenotypes with CCDC81: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC81

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC81 Gene

Localization for CCDC81 Gene

Subcellular locations from

Jensen Localization Image for CCDC81 Gene COMPARTMENTS Subcellular localization image for CCDC81 gene
Compartment Confidence
cytosol 2
nucleus 2
plasma membrane 2

Gene Ontology (GO) - Cellular Components for CCDC81 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005813 centrosome IDA 25074808
genes like me logo Genes that share ontologies with CCDC81: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CCDC81 Gene

Pathways for CCDC81 Gene

SuperPathways for CCDC81 Gene

No Data Available

Interacting Proteins for CCDC81 Gene

Gene Ontology (GO) - Biological Process for CCDC81 Gene


No data available for Pathways by source for CCDC81 Gene

Transcripts for CCDC81 Gene

Unigene Clusters for CCDC81 Gene

Coiled-coil domain containing 81:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC81

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC81 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15a · 15b
SP1: - - - -
SP2: - -
SP3: - - - - -
SP4: - -
SP5: - - - -
SP6: - - - - - -

Relevant External Links for CCDC81 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC81 Gene

mRNA expression in normal human tissues for CCDC81 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC81 Gene

This gene is overexpressed in Testis (5.5) and Fallopian Tube (5.5).

SOURCE GeneReport for Unigene cluster for CCDC81 Gene Hs.144913

genes like me logo Genes that share expressions with CCDC81: view

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for CCDC81 Gene

Orthologs for CCDC81 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC81 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC81 35
  • 85.02 (n)
  • 80.06 (a)
CCDC81 36
  • 80 (a)
(Canis familiaris)
Mammalia CCDC81 35
  • 87.3 (n)
  • 82.64 (a)
CCDC81 36
  • 82 (a)
(Mus musculus)
Mammalia Ccdc81 35
  • 83 (n)
  • 78.8 (a)
Ccdc81 16
Ccdc81 36
  • 79 (a)
(Pan troglodytes)
Mammalia CCDC81 35
  • 98.93 (n)
  • 98.47 (a)
CCDC81 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Ccdc81 35
  • 83.13 (n)
  • 79.48 (a)
(Monodelphis domestica)
Mammalia CCDC81 36
  • 61 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC81 36
  • 51 (a)
(Gallus gallus)
Aves -- 36
  • 38 (a)
-- 36
  • 23 (a)
-- 36
  • 22 (a)
-- 36
  • 28 (a)
(Anolis carolinensis)
Reptilia CCDC81 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc81 35
  • 58.41 (n)
  • 50.78 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 42 (a)
Species with no ortholog for CCDC81:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC81 Gene

Gene Tree for CCDC81 (if available)
Gene Tree for CCDC81 (if available)

Paralogs for CCDC81 Gene

No data available for Paralogs for CCDC81 Gene

Variants for CCDC81 Gene

Sequence variations from dbSNP and Humsavar for CCDC81 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs167109 -- 86,377,645(-) aacac(A/T)aagaa intron-variant
rs176762 -- 86,399,104(+) ttaaa(A/T)gttga intron-variant
rs292091 -- 86,376,182(-) TGTGA(C/T)TATTT intron-variant
rs292092 -- 86,375,539(-) CAGCG(A/G)GTGGT intron-variant
rs292093 -- 86,375,351(-) GCCAC(G/T)GCAGG intron-variant

Relevant External Links for CCDC81 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCDC81 Gene

Disorders for CCDC81 Gene

Relevant External Links for CCDC81

Genetic Association Database (GAD)

No disorders were found for CCDC81 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for CCDC81 Gene

Publications for CCDC81 Gene

  1. Proteomic analysis of mammalian sperm cells identifies new components of the centrosome. (PMID: 25074808) Firat-Karalar E.N. … Stearns T. (J. Cell Sci. 2014) 2 3
  2. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PMID: 17903296) Kiel D.P. … Karasik D. (BMC Med. Genet. 2007) 48
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PMID: 8125298) Maruyama K. … Sugano S. (Gene 1994) 3

Products for CCDC81 Gene

Sources for CCDC81 Gene

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