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Aliases for CCDC81 Gene

Aliases for CCDC81 Gene

  • Coiled-Coil Domain Containing 81 2 3 5

External Ids for CCDC81 Gene

Previous GeneCards Identifiers for CCDC81 Gene

  • GC11P085764
  • GC11P086085
  • GC11P082374

Summaries for CCDC81 Gene

GeneCards Summary for CCDC81 Gene

CCDC81 (Coiled-Coil Domain Containing 81) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC81 Gene

Genomics for CCDC81 Gene

Regulatory Elements for CCDC81 Gene

Enhancers for CCDC81 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CCDC81 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC81 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CCDC81 on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC81 Gene

86,374,736 bp from pter
86,423,109 bp from pter
48,374 bases
Plus strand

Genomic View for CCDC81 Gene

Genes around CCDC81 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC81 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC81 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC81 Gene

Proteins for CCDC81 Gene

  • Protein details for CCDC81 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 81
    Protein Accession:
    Secondary Accessions:
    • A0AVL7
    • Q53FW3
    • Q9H5E5

    Protein attributes for CCDC81 Gene

    652 amino acids
    Molecular mass:
    76084 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAD96888.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC81 Gene


neXtProt entry for CCDC81 Gene

Proteomics data for CCDC81 Gene at MOPED

Post-translational modifications for CCDC81 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC81 Gene

No data available for DME Specific Peptides for CCDC81 Gene

Domains & Families for CCDC81 Gene

Protein Domains for CCDC81 Gene

Suggested Antigen Peptide Sequences for CCDC81 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC81: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC81 Gene

Function for CCDC81 Gene

Phenotypes for CCDC81 Gene

genes like me logo Genes that share phenotypes with CCDC81: view

Animal Model Products

miRNA for CCDC81 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC81 Gene

Localization for CCDC81 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CCDC81 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Subcellular locations from

Jensen Localization Image for CCDC81 Gene COMPARTMENTS Subcellular localization image for CCDC81 gene
Compartment Confidence
cytoskeleton 5
cytosol 2
nucleus 2
plasma membrane 2

Gene Ontology (GO) - Cellular Components for CCDC81 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with CCDC81: view

Pathways & Interactions for CCDC81 Gene

SuperPathways for CCDC81 Gene

No Data Available

Interacting Proteins for CCDC81 Gene

Gene Ontology (GO) - Biological Process for CCDC81 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC81 Gene

Drugs & Compounds for CCDC81 Gene

No Compound Related Data Available

Transcripts for CCDC81 Gene

Unigene Clusters for CCDC81 Gene

Coiled-coil domain containing 81:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC81 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15a · 15b
SP1: - - - -
SP2: - -
SP3: - - - - -
SP4: - -
SP5: - - - -
SP6: - - - - - -

Relevant External Links for CCDC81 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC81 Gene

mRNA expression in normal human tissues for CCDC81 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC81 Gene

This gene is overexpressed in Testis (x5.5) and Fallopian Tube (x5.5).

SOURCE GeneReport for Unigene cluster for CCDC81 Gene Hs.144913

genes like me logo Genes that share expression patterns with CCDC81: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CCDC81 Gene

Orthologs for CCDC81 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC81 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC81 35
  • 85.02 (n)
  • 80.06 (a)
CCDC81 36
  • 80 (a)
(Canis familiaris)
Mammalia CCDC81 35
  • 87.3 (n)
  • 82.64 (a)
CCDC81 36
  • 82 (a)
(Mus musculus)
Mammalia Ccdc81 35
  • 83 (n)
  • 78.8 (a)
Ccdc81 16
Ccdc81 36
  • 79 (a)
(Pan troglodytes)
Mammalia CCDC81 35
  • 98.93 (n)
  • 98.47 (a)
CCDC81 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Ccdc81 35
  • 83.13 (n)
  • 79.48 (a)
(Monodelphis domestica)
Mammalia CCDC81 36
  • 61 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC81 36
  • 51 (a)
(Gallus gallus)
Aves -- 36
  • 38 (a)
-- 36
  • 23 (a)
-- 36
  • 22 (a)
-- 36
  • 28 (a)
(Anolis carolinensis)
Reptilia CCDC81 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc81 35
  • 58.41 (n)
  • 50.78 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 42 (a)
Species with no ortholog for CCDC81:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC81 Gene

Gene Tree for CCDC81 (if available)
Gene Tree for CCDC81 (if available)

Paralogs for CCDC81 Gene

No data available for Paralogs for CCDC81 Gene

Variants for CCDC81 Gene

Sequence variations from dbSNP and Humsavar for CCDC81 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs3741005 - 86,412,514(-) CTCTG(C/T)ATTGT reference, missense
rs539196 -- 86,402,071(+) tggag(C/G)ttgca intron-variant
rs563307 -- 86,417,625(+) CTTTG(G/T)TTCCA intron-variant
rs572982 -- 86,400,728(-) CACTT(G/T)GGCAG reference, missense, utr-variant-5-prime
rs576759 -- 86,421,931(+) aaTCC(A/C)CCCAT intron-variant

Variation tolerance for CCDC81 Gene

Residual Variation Intolerance Score: 83.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.81; 73.74% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CCDC81 Gene

Disorders for CCDC81 Gene

Relevant External Links for CCDC81

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC81 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC81 Gene

Publications for CCDC81 Gene

  1. Proteomic analysis of mammalian sperm cells identifies new components of the centrosome. (PMID: 25074808) Firat-Karalar E.N. … Stearns T. (J. Cell Sci. 2014) 2 3 4 67
  2. Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. (PMID: 25017104) Kottyan L.C. … Rothenberg M.E. (Nat. Genet. 2014) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PMID: 8125298) Maruyama K. … Sugano S. (Gene 1994) 3

Products for CCDC81 Gene

Sources for CCDC81 Gene