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Aliases for CCDC73 Gene

Aliases for CCDC73 Gene

  • Coiled-Coil Domain Containing 73 2 3
  • Sarcoma Antigen NY-SAR-79 3 4
  • Coiled-Coil Domain-Containing Protein 73 3
  • NY-SAR-79 3

External Ids for CCDC73 Gene

Previous GeneCards Identifiers for CCDC73 Gene

  • GC11M032582
  • GC11M032318

Summaries for CCDC73 Gene

GeneCards Summary for CCDC73 Gene

CCDC73 (Coiled-Coil Domain Containing 73) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC73 Gene

Genomics for CCDC73 Gene

Regulatory Elements for CCDC73 Gene

Genomic Location for CCDC73 Gene

Start:
32,602,080 bp from pter
End:
32,794,658 bp from pter
Size:
192,579 bases
Orientation:
Minus strand

Genomic View for CCDC73 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC73 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC73 Gene

Proteins for CCDC73 Gene

  • Protein details for CCDC73 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZRK6-CCD73_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 73
    Protein Accession:
    Q6ZRK6
    Secondary Accessions:
    • Q6P5Q7
    • Q6ZMW0
    • Q86WE7

    Protein attributes for CCDC73 Gene

    Size:
    1079 amino acids
    Molecular mass:
    124154 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH62749.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAO65175.1; Type=Frameshift; Positions=Several; Evidence={ECO:0000305}; Sequence=BAC87304.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAD18615.1; Type=Frameshift; Positions=448; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC73 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC73 Gene

Proteomics data for CCDC73 Gene at MOPED

Post-translational modifications for CCDC73 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC73 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC73 Gene

Domains for CCDC73 Gene

Protein Domains for CCDC73 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CCDC73 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC73: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC73 Gene

Function for CCDC73 Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC73

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC73 Gene

Localization for CCDC73 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC73 Gene COMPARTMENTS Subcellular localization image for CCDC73 gene
Compartment Confidence
nucleus 2
cytosol 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC73 Gene

Pathways for CCDC73 Gene

SuperPathways for CCDC73 Gene

No Data Available

Interacting Proteins for CCDC73 Gene

Gene Ontology (GO) - Biological Process for CCDC73 Gene

None

No data available for Pathways by source for CCDC73 Gene

Transcripts for CCDC73 Gene

mRNA/cDNA for CCDC73 Gene

(5) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC73 Gene

Coiled-coil domain containing 73:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC73

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for CCDC73

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC73 Gene

No ASD Table

Relevant External Links for CCDC73 Gene

GeneLoc Exon Structure for
CCDC73
ECgene alternative splicing isoforms for
CCDC73

Expression for CCDC73 Gene

mRNA expression in normal human tissues for CCDC73 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC73 Gene

This gene is overexpressed in Testis (22.5).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC73 Gene

SOURCE GeneReport for Unigene cluster for CCDC73 Gene Hs.706808

genes like me logo Genes that share expressions with CCDC73: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for CCDC73 Gene

Orthologs for CCDC73 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC73 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC73 35
  • 99.47 (n)
  • 99.07 (a)
CCDC73 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC73 35
  • 86.64 (n)
  • 76.27 (a)
CCDC73 36
  • 76 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC73 35
  • 87.1 (n)
  • 77.7 (a)
CCDC73 36
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc73 35
  • 77.41 (n)
  • 62.92 (a)
Ccdc73 16
Ccdc73 36
  • 61 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC73 36
  • 47 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC73 36
  • 50 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc73 35
  • 76.65 (n)
  • 62.64 (a)
chicken
(Gallus gallus)
Aves CCDC73 36
  • 39 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC73 36
  • 64 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ccdc73 36
  • 31 (a)
OneToOne
Species with no ortholog for CCDC73:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC73 Gene

ENSEMBL:
Gene Tree for CCDC73 (if available)
TreeFam:
Gene Tree for CCDC73 (if available)

Paralogs for CCDC73 Gene

No data available for Paralogs for CCDC73 Gene

Variants for CCDC73 Gene

Sequence variations from dbSNP and Humsavar for CCDC73 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs156160 -- 32,752,023(-) tgagc(A/G)gaagt intron-variant
rs156161 -- 32,750,653(-) agtgg(C/T)accct intron-variant
rs156162 -- 32,748,827(-) gaata(C/G)tatgt intron-variant
rs156163 -- 32,743,082(-) gctac(C/T)tgact intron-variant
rs172100 -- 32,644,526(+) aggtg(C/T)ataat intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC73 Gene

Variant ID Type Subtype PubMed ID
nsv832109 CNV Gain 17160897
nsv897189 CNV Gain 21882294
essv7540 CNV CNV 17122850
esv2744317 CNV Deletion 23290073
esv270137 CNV Insertion 20981092
esv2646311 CNV Deletion 19546169
esv2744318 CNV Deletion 23290073
esv1483356 CNV Deletion 17803354
essv6421 CNV CNV 17122850
esv34742 CNV Gain 17911159
nsv897190 CNV Gain 21882294
nsv897191 CNV Gain 21882294

Relevant External Links for CCDC73 Gene

HapMap Linkage Disequilibrium report
CCDC73

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC73 Gene

Disorders for CCDC73 Gene

Relevant External Links for CCDC73

Genetic Association Database (GAD)
CCDC73
Human Genome Epidemiology (HuGE) Navigator
CCDC73
genes like me logo Genes that share disorders with CCDC73: view

No data available for UniProtKB/Swiss-Prot for CCDC73 Gene

Publications for CCDC73 Gene

  1. Immunomic analysis of human sarcoma. (PMID: 12601173) Lee S.-Y. … Scanlan M.J. (Proc. Natl. Acad. Sci. U.S.A. 2003) 3 4
  2. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. (PMID: 18519826) Uhl G.R. … Lerman C. (Arch. Gen. Psychiatry 2008) 3 48
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for CCDC73 Gene

Sources for CCDC73 Gene

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