CCDC71L Gene
protein-coding GIFtS: 35
GCID: GC07M106298
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coiled-coil domain containing 71-like(Previous name: chromosome 7 open reading frame 74 )
(Previous symbol: C7orf74)
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Aliases
for CCDC71L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Coiled-Coil Domain Containing 71-Like1 2 | | C7orf741 2 3 | | FLJ360311 | | Chromosome 7 Open Reading Frame 741 | | Coiled-Coil Domain-Containing Protein 71L2 |
| External Ids: | HGNC: 266851 | Entrez Gene: 1684552 | Ensembl: ENSG000002532767 | UniProtKB: Q8N9Z23 | | ORGUL members: | |
|---|
| NONCODE:n341294 | |
Export aliases for CCDC71L gene to outside databases
|---|
Summaries
for CCDC71L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCDC71L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for CCDC71L
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC71L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC71L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q22.3 Ensembl cytogenetic band: 7q22.3 HGNC cytogenetic band: 7q22.3CCDC71L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M106298: view genomic region
(about GC identifiers)
Start:
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106,297,211 bp from pter |
End:
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106,301,591 bp from pter |
Size:
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4,381 bases |
Orientation:
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minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 105,660,265-105,662,707 |
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Proteins
for CCDC71L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CC71L_HUMAN, Q8N9Z2 (See
protein sequence)Recommended Name: Coiled-coil domain-containing protein 71L Size: 235 amino acids; 26261 Da
Sequence caution: Sequence=AAH13906.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=EAL24398.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q7Z756Alternative splicing: 2 isoforms: Q8N9Z2-1 Q8N9Z2-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CCDC71L: NX_Q8N9Z2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N9Z2
CCDC71L Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_787080.2
ENSEMBL proteins: ENSP00000430897
Human Recombinant Protein Products:
CCDC71L Antibody Products:
Assay Products for CCDC71L: |
Protein
Domains /
Families
for CCDC71L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CCDC71L for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8N9Z2ProtoNet protein and cluster: Q8N9Z2 |
Function
for CCDC71L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC71L (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC71L
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for CCDC71L | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC71L | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC71L |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC71L |
1 GenomeRNAi human phenotype for CCDC71L:
|
Pathways & Interactions
for CCDC71L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC71L
|
Drugs & Compounds
for CCDC71L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCDC71L
Search CenterWatch for drugs/clinical trials and news about CCDC71L / CC71L
|
Transcripts
for CCDC71L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCDC71L gene: NM_175884.4 Unigene Clusters for CCDC71L: Coiled-coil domain containing 71-like Hs.29692 [show with all ESTs], Hs.633903 [show with all ESTs]Unigene Representative Sequences: NM_175884, AK0984221 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000523505(uc003vdt.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC71L (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC71L
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for CCDC71L | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC71L | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC71L |
Additional cDNA sequence: AK021498.1 AK098422.1 4 DOTS entries: DT.40208778 DT.312769 DT.100671132 DT.121110529 24/169 AceView cDNA sequences (see all 169): AA235301 AA234817 AI281339 BM128536 AI274215 AI825765 BF434080 AI384116 AA424813 CA397148 BF439215 AI350754 BE466274 BX095845 BE271810 AI671810 AK093350 BM068758 AI274384 AU117354 BE466269 CK904413 BC013906 AA187538
GeneLoc Exon Structure
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Expression
for CCDC71L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCDC71L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAAACTTTTG
About this image
See CCDC71L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCDC71L
SOURCE GeneReport for Unigene clusters: Hs.29692 Hs.633903
SABiosciences Custom PCR Arrays for CCDC71L
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC71L
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat CCDC71L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC71L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC71L | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC71L |
Orthologs
for CCDC71L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CCDC71L gene from 2/7 species (see all 7) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
C7orf746 |
-- |
50(a) |
1 ↔ 1 |
5(97069200-97069850) |
zebrafish
(Danio rerio) |
Actinopterygii |
si:dkeyp-87e7.46 |
si:dkeyp-87e7.4 |
14(a) |
1 → many |
22(10342677-10372591) |
ENSEMBL Gene Tree for CCDC71L (if available)
TreeFam Gene Tree for CCDC71L (if available) |
Paralogs
for CCDC71L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CCDC71L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCDC71L (106297211 - 106301591 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CCDC71L: -- | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for CCDC71L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CCDC71L for disorders About GeneDecksing
1  disease for CCDC71L: About MalaCardschoroiditis
Export disorders for CCDC71L gene to outside databases
|
Publications
for CCDC71L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCDC71L gene integrated from 9 sources:
(articles sorted by number of sources associating them with CCDC71L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
- Expressed sequence tag analysis of human RPE/choroid for the NEIBank project: over 6000 non-redundant transcripts, novel genes and splice variants. (PubMed id 12107410)1 Wistow G.... Peterson K. (2002)
- Generation and analysis of 280,000 human expressed sequence tags. (PubMed id 8889549)1 Hillier L.D....Marra M. (1996)
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External Searches for CCDC71L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCDC71L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC71L gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCDC71L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CCDC71L gene:
Search GeneIP for patents involving CCDC71L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC71L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CCDC71L | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCDC71L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC71L | | | OriGene Protein Over-expression Lysate for CCDC71L | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCDC71L | | OriGene 3'-UTR Clone for CCDC71L | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC71L | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC71L | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCDC71L | | OriGene Custom Protein Services for CCDC71L | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC71L | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC71L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC71L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCDC71L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC71L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC71L |
| |
 |  |  |  | |
| | | | Search Tocris compounds for CCDC71L |
| |  |  |  |  | | | | |
 |
 |
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 | | | CCDC71L Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC71L |
|  |  |  | | | | Search ThermoFisher Antibodies for CCDC71L |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC71L |
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