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Aliases for CCDC71 Gene

Aliases for CCDC71 Gene

  • Coiled-Coil Domain Containing 71 2 3 5
  • Coiled-Coil Domain-Containing Protein 71 3
  • 2600016J21Rik 3

External Ids for CCDC71 Gene

Previous GeneCards Identifiers for CCDC71 Gene

  • GC03M049174

Summaries for CCDC71 Gene

GeneCards Summary for CCDC71 Gene

CCDC71 (Coiled-Coil Domain Containing 71) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC71 Gene

Genomics for CCDC71 Gene

Regulatory Elements for CCDC71 Gene

Enhancers for CCDC71 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F049356 0.2 ENCODE 25.9 -191.9 -191935 4.2 HDGF MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF143 AMT QRICH1 CCDC71 LAMB2 IMPDH2 RHOA-IT1 TMEM89 SEMA3F-AS1 FAM212A DAG1
GH03F049217 1.3 Ensembl ENCODE 23.4 -52.3 -52330 2.1 MLX ZNF133 ARID4B DMAP1 ZNF48 GTF3C2 SLC30A9 FOS SP5 PPARG AMT WDR6 QRICH1 CCDC71 NME6 MRPS18AP1 ZNF589 SEMA3F-AS1 RHOA-IT1 CCDC36
GH03F049409 1 Ensembl ENCODE 22.2 -247.5 -247455 8.9 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF207 ZNF143 AMT CCDC71 WDR6 SEMA3F-AS1 QRICH1 FAM212A RNA5SP130 DAG1 TMEM115 USP4
GH03F048917 1 ENCODE 21.7 +247.5 247534 3.4 PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 SP3 SP5 ZHX2 MXD4 REST WDR6 QRICH1 CCDC71 NME6 RHOA-IT1 ZNF589 AMT ARIH2 SLC25A20
GH03F049428 0.4 ENCODE 21.3 -263.1 -263149 1.8 PKNOX1 CREB3L1 MLX ARID4B SIN3A YBX1 DMAP1 ZNF2 YY1 ZNF766 AMT TMEM115 QRICH1 LAMB2 CCDC71 IMPDH2 NICN1 WDR6 RHOA-IT1 SEMA3F-AS1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around CCDC71 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC71 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001363586 252 1401 HDGF PKNOX1 MLX ARID4B SIN3A DMAP1 ETS1 YY1 GTF3C2 ELK1

Genomic Location for CCDC71 Gene

Chromosome:
3
Start:
49,162,535 bp from pter
End:
49,166,352 bp from pter
Size:
3,818 bases
Orientation:
Minus strand

Genomic View for CCDC71 Gene

Genes around CCDC71 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC71 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC71 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC71 Gene

Proteins for CCDC71 Gene

  • Protein details for CCDC71 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IV32-CCD71_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 71
    Protein Accession:
    Q8IV32
    Secondary Accessions:
    • Q6IPE2
    • Q9H8H4
    • Q9H9F1

    Protein attributes for CCDC71 Gene

    Size:
    467 amino acids
    Molecular mass:
    49648 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14642.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for CCDC71 Gene

Post-translational modifications for CCDC71 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC71 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC71 Gene

Domains & Families for CCDC71 Gene

Protein Domains for CCDC71 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC71 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC71: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC71 Gene

Function for CCDC71 Gene

genes like me logo Genes that share phenotypes with CCDC71: view

Animal Model Products

miRNA for CCDC71 Gene

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC71 Gene

Localization for CCDC71 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC71 Gene COMPARTMENTS Subcellular localization image for CCDC71 gene
Compartment Confidence
nucleus 4
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC71 Gene

Pathways & Interactions for CCDC71 Gene

SuperPathways for CCDC71 Gene

No Data Available

Interacting Proteins for CCDC71 Gene

Gene Ontology (GO) - Biological Process for CCDC71 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CCDC71 Gene

Transcripts for CCDC71 Gene

mRNA/cDNA for CCDC71 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(46) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC71 Gene

Coiled-coil domain containing 71:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC71 Gene

No ASD Table

Relevant External Links for CCDC71 Gene

GeneLoc Exon Structure for
CCDC71
ECgene alternative splicing isoforms for
CCDC71

Expression for CCDC71 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CCDC71 Gene

Protein differential expression in normal tissues from HIPED for CCDC71 Gene

This gene is overexpressed in Saliva (27.1), Placenta (15.7), Esophagus (11.3), and Frontal cortex (8.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CCDC71 Gene



NURSA nuclear receptor signaling pathways regulating expression of CCDC71 Gene:

CCDC71

SOURCE GeneReport for Unigene cluster for CCDC71 Gene:

Hs.211472
genes like me logo Genes that share expression patterns with CCDC71: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for CCDC71 Gene

Orthologs for CCDC71 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC71 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC71 34 35
  • 96.94 (n)
dog
(Canis familiaris)
Mammalia CCDC71 35
  • 86 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC71 35
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc71 35
  • 76 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC71 35
  • 57 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC71 35
  • 47 (a)
OneToOne
chicken
(Gallus gallus)
Aves CCDC71 35
  • 48 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC71 35
  • 47 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CCDC71 35
  • 28 (a)
OneToOne
Species where no ortholog for CCDC71 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC71 Gene

ENSEMBL:
Gene Tree for CCDC71 (if available)
TreeFam:
Gene Tree for CCDC71 (if available)

Paralogs for CCDC71 Gene

No data available for Paralogs for CCDC71 Gene

Variants for CCDC71 Gene

Sequence variations from dbSNP and Humsavar for CCDC71 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs112499314 -- 49,166,909(+) CAAGC(A/G)CACAT upstream-variant-2KB
rs11308803 -- 49,166,144(+) GGGGG(-/G)TCTCG intron-variant
rs1134043 -- 49,162,704(-) ACTCC(A/C)GGTGC utr-variant-3-prime
rs113754979 -- 49,162,865(+) ACGCG(A/G)AGGAT reference, synonymous-codon
rs115337389 -- 49,163,307(+) GTGTT(C/G)GAGCC reference, missense

Structural Variations from Database of Genomic Variants (DGV) for CCDC71 Gene

Variant ID Type Subtype PubMed ID
nsv834686 CNV loss 17160897

Variation tolerance for CCDC71 Gene

Residual Variation Intolerance Score: 58.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.47; 28.78% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC71 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CCDC71

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC71 Gene

Disorders for CCDC71 Gene

Relevant External Links for CCDC71

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CCDC71

No disorders were found for CCDC71 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC71 Gene

Publications for CCDC71 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  5. The central role of EED in the orchestration of polycomb group complexes. (PMID: 24457600) Cao Q. … Chinnaiyan A.M. (Nat Commun 2014) 3 64

Products for CCDC71 Gene

Sources for CCDC71 Gene

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