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Aliases for CCDC7 Gene

Aliases for CCDC7 Gene

  • Coiled-Coil Domain Containing 7 2 3
  • Chromosome 10 Open Reading Frame 68 2
  • Uncharacterized Protein C10orf68 3
  • Protein BIOT2 4
  • C16orf25 6
  • C10orf68 3
  • BioT2-A 3
  • BioT2-B 3
  • BioT2-C 3
  • CCDC78 6
  • BIOT2 4
  • CNM4 6

External Ids for CCDC7 Gene

Previous Symbols for CCDC7 Gene

  • C10orf68

Summaries for CCDC7 Gene

GeneCards Summary for CCDC7 Gene

CCDC7 (Coiled-Coil Domain Containing 7) is a Protein Coding gene.

UniProtKB/Swiss-Prot for CCDC7 Gene

  • May play a role in tumorigenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC7 Gene

Genomics for CCDC7 Gene

Genomic Location for CCDC7 Gene

Start:
32,446,082 bp from pter
End:
32,882,874 bp from pter
Size:
436,793 bases
Orientation:
Plus strand

Genomic View for CCDC7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC7 Gene

Regulatory Elements for CCDC7 Gene

Proteins for CCDC7 Gene

  • Protein details for CCDC7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96M83-CCDC7_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 7
    Protein Accession:
    Q96M83
    Secondary Accessions:
    • Q5VW55
    • Q8IVQ0
    • Q8NEQ0

    Protein attributes for CCDC7 Gene

    Size:
    486 amino acids
    Molecular mass:
    55780 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CCDC7 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC7 Gene

Proteomics data for CCDC7 Gene at MOPED

Post-translational modifications for CCDC7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC7 Gene

No data available for DME Specific Peptides for CCDC7 Gene

Domains for CCDC7 Gene

Protein Domains for CCDC7 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CCDC7 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC7: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC7 Gene

Function for CCDC7 Gene

Molecular function for CCDC7 Gene

UniProtKB/Swiss-Prot Function: May play a role in tumorigenesis.

miRNA for CCDC7 Gene

miRTarBase miRNAs that target CCDC7

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCDC7 Gene

Localization for CCDC7 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC7 Gene COMPARTMENTS Subcellular localization image for CCDC7 gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC7 Gene

Pathways for CCDC7 Gene

SuperPathways for CCDC7 Gene

No Data Available

Interacting Proteins for CCDC7 Gene

Selected Interacting proteins: Q96M83-CCDC7_HUMAN for CCDC7 Gene via MINT I2D

Gene Ontology (GO) - Biological Process for CCDC7 Gene

None

No data available for Pathways by source for CCDC7 Gene

Transcripts for CCDC7 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC7 Gene

No ASD Table

Relevant External Links for CCDC7 Gene

GeneLoc Exon Structure for
CCDC7
ECgene alternative splicing isoforms for
CCDC7

Expression for CCDC7 Gene

mRNA expression in normal human tissues for CCDC7 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC7 Gene

This gene is overexpressed in Testis (10.5).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CCDC7 Gene

mRNA Expression by UniProt/SwissProt for CCDC7 Gene

Q96M83-CCDC7_HUMAN
Tissue specificity: Expressed in epithelium of normal cervix and cervical cancer. Overexpressed in early and interim cervical cancer.
genes like me logo Genes that share expressions with CCDC7: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for CCDC7 Gene

Orthologs for CCDC7 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CCDC7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 89 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC7 35
  • 83.05 (n)
  • 69.49 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 34 (a)
OneToOne
CCDC7 35
  • 83.02 (n)
  • 69.13 (a)
mouse
(Mus musculus)
Mammalia 1700008F21Rik 35
  • 64.34 (n)
  • 43.7 (a)
rat
(Rattus norvegicus)
Mammalia Ccdc7 35
  • 68.46 (n)
  • 53.74 (a)
Species with no ortholog for CCDC7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC7 Gene

ENSEMBL:
Gene Tree for CCDC7 (if available)
TreeFam:
Gene Tree for CCDC7 (if available)

Paralogs for CCDC7 Gene

Selected SIMAP similar genes for CCDC7 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with CCDC7: view

No data available for Paralogs for CCDC7 Gene

Variants for CCDC7 Gene

Sequence variations from dbSNP and Humsavar for CCDC7 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs881034 -- 32,865,982(+) CAAAC(A/G)CACAC intron-variant
rs885116 -- 32,472,847(+) CACCT(C/G/T)GGGCT intron-variant
rs928701 -- 32,726,854(+) TAGAT(A/G)ACTTT intron-variant
rs944823 -- 32,468,590(+) CTGAT(A/T)GCTCT intron-variant
rs944824 -- 32,475,313(+) TTCCA(C/G)TTTAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC7 Gene

Variant ID Type Subtype PubMed ID
esv275237 CNV Gain+Loss 21479260
dgv631n71 CNV Gain 21882294
nsv895005 CNV Loss 21882294
esv24286 CNV Gain 19812545

Relevant External Links for CCDC7 Gene

HapMap Linkage Disequilibrium report
CCDC7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC7 Gene

Disorders for CCDC7 Gene

(1) OMIM Diseases for CCDC7 Gene (614666)

Relevant External Links for CCDC7

Genetic Association Database (GAD)
CCDC7
Human Genome Epidemiology (HuGE) Navigator
CCDC7
genes like me logo Genes that share disorders with CCDC7: view

No data available for UniProtKB/Swiss-Prot for CCDC7 Gene

Publications for CCDC7 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  5. Overexpression of the hBiot2 gene is associated with development of human cervical cancer. (PMID: 21109960) Shen Y.M. … Zhao X. (Oncol. Rep. 2011) 3 4

Products for CCDC7 Gene

Sources for CCDC7 Gene

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