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Aliases for CCDC69 Gene

Aliases for CCDC69 Gene

  • Coiled-Coil Domain Containing 69 2 3

External Ids for CCDC69 Gene

Previous GeneCards Identifiers for CCDC69 Gene

  • GC05M150541
  • GC05M145706
  • GC05M150560

Summaries for CCDC69 Gene

GeneCards Summary for CCDC69 Gene

CCDC69 (Coiled-Coil Domain Containing 69) is a Protein Coding gene. An important paralog of this gene is MTUS2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC69 Gene

Genomics for CCDC69 Gene

Regulatory Elements for CCDC69 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CCDC69 Gene

151,181,052 bp from pter
151,224,145 bp from pter
43,094 bases
Minus strand

Genomic View for CCDC69 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC69 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC69 Gene

Proteins for CCDC69 Gene

  • Protein details for CCDC69 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 69
    Protein Accession:
    Secondary Accessions:
    • A8K9X6

    Protein attributes for CCDC69 Gene

    296 amino acids
    Molecular mass:
    34796 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC69 Gene

Proteomics data for CCDC69 Gene at MOPED

Post-translational modifications for CCDC69 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC69 Gene

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for CCDC69

No data available for DME Specific Peptides for CCDC69 Gene

Domains for CCDC69 Gene

Protein Domains for CCDC69 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC69: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC69 Gene

Function for CCDC69 Gene

Animal Model Products

miRNA for CCDC69 Gene

miRTarBase miRNAs that target CCDC69

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CCDC69 Gene

Localization for CCDC69 Gene

Subcellular locations from

Jensen Localization Image for CCDC69 Gene COMPARTMENTS Subcellular localization image for CCDC69 gene
Compartment Confidence
nucleus 3
cytosol 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for CCDC69 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum --
genes like me logo Genes that share ontologies with CCDC69: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CCDC69 Gene

Pathways for CCDC69 Gene

SuperPathways for CCDC69 Gene

No Data Available

Interacting Proteins for CCDC69 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: A6NI79-CCD69_HUMAN ENSP00000347586 for CCDC69 Gene via MINT STRING I2D

Gene Ontology (GO) - Biological Process for CCDC69 Gene


No data available for Pathways by source for CCDC69 Gene

Transcripts for CCDC69 Gene

Unigene Clusters for CCDC69 Gene

Coiled-coil domain containing 69:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CCDC69

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC69 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b · 9c ^ 10a · 10b ^ 11
SP1: - -
SP2: - -
SP3: - - - - - -
SP4: - - -
SP5: - - -
SP6: - -
SP7: -

Relevant External Links for CCDC69 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC69 Gene

mRNA expression in normal human tissues for CCDC69 Gene

mRNA differential expression in normal tissues according to GTEx for CCDC69 Gene

This gene is overexpressed in Whole Blood (4.2).

Protein differential expression in normal tissues for CCDC69 Gene

This gene is overexpressed in Plasma (28.9), Serum (17.0), and Monocytes (11.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CCDC69 Gene

SOURCE GeneReport for Unigene cluster for CCDC69 Gene Hs.655336

genes like me logo Genes that share expressions with CCDC69: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Expression partners for CCDC69 Gene

Orthologs for CCDC69 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC69 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC69 35
  • 85.49 (n)
  • 82.99 (a)
CCDC69 36
  • 82 (a)
(Canis familiaris)
Mammalia CCDC69 35
  • 86.51 (n)
  • 83.67 (a)
CCDC69 36
  • 79 (a)
(Pan troglodytes)
Mammalia CCDC69 35
  • 99.43 (n)
  • 99.29 (a)
CCDC69 36
  • 95 (a)
(Mus musculus)
Mammalia Ccdc69 16
Ccdc69 36
  • 48 (a)
(Monodelphis domestica)
Mammalia CCDC69 36
  • 60 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC69 36
  • 50 (a)
(Gallus gallus)
Aves CCDC69 35
  • 66.53 (n)
  • 56.54 (a)
CCDC69 36
  • 44 (a)
(Anolis carolinensis)
Reptilia CCDC69 36
  • 76 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc69 35
  • 55.76 (n)
  • 43.88 (a)
(Danio rerio)
Actinopterygii ccdc69 35
  • 54.48 (n)
  • 37.82 (a)
CABZ01005777.1 36
  • 27 (a)
Species with no ortholog for CCDC69:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC69 Gene

Gene Tree for CCDC69 (if available)
Gene Tree for CCDC69 (if available)

Paralogs for CCDC69 Gene

Paralogs for CCDC69 Gene

Selected SIMAP similar genes for CCDC69 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with CCDC69: view

Variants for CCDC69 Gene

Sequence variations from dbSNP and Humsavar for CCDC69 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs152264 -- 151,220,524(-) GCTGG(A/T)GCAGG intron-variant
rs152265 -- 151,220,413(-) CAGTC(C/T)TGACT intron-variant
rs153462 -- 151,225,509(+) ATGAG(A/G)CCTCA upstream-variant-2KB
rs153463 -- 151,225,139(+) AATAA(A/T)ACTAA upstream-variant-2KB
rs153464 -- 151,222,804(+) ATTTC(A/G)ATCTG intron-variant

Relevant External Links for CCDC69 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CCDC69 Gene

Disorders for CCDC69 Gene

No disorders were found for CCDC69 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CCDC69 Gene

Publications for CCDC69 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Role of a novel coiled-coil domain-containing protein CCDC69 in regulating central spindle assembly. (PMID: 20962590) Pal D. … Wei Q. (Cell Cycle 2010) 3
  4. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3
  5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3

Products for CCDC69 Gene

Sources for CCDC69 Gene

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