CCDC69 Gene
protein-coding GIFtS: 41
GCID: GC05M150560
|
|
coiled-coil domain containing 69
| |
Aliases
for CCDC69 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Coiled-Coil Domain Containing 691 2 | | DKFZP434C1711 | | FLJ137051 | | Coiled-Coil Domain-Containing Protein 692 |
Export aliases for CCDC69 gene to outside databasesPrevious GC identifers: GC05M150541 GC05M145706 |
Summaries
for CCDC69 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCDC69 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_029289.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCDC69 gene promoter:
USF1 NRSF form 1 SREBP-1c NRSF form 2 Tal-1beta SREBP-1b SREBP-1a USF-1 MRF-2 ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC69
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC69 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q33.1 Ensembl cytogenetic band: 5q33.1 HGNC cytogenetic band: 5q33.1CCDC69 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M150560: view genomic region
(about GC identifiers)
Start:
|
150,560,613 bp from pter |
End:
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150,603,706 bp from pter |
Size:
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43,094 bases |
Orientation:
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minus strand |
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Proteins
for CCDC69 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CCD69_HUMAN, A6NI79 (See
protein sequence)Recommended Name: Coiled-coil domain-containing protein 69 Size: 296 amino acids; 34796 Da
Secondary accessions: A8K9X6Explore the universe of human proteins at neXtProt for CCDC69: NX_A6NI79
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A6NI79
CCDC69 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_056436.2
ENSEMBL proteins: ENSP00000347586 ENSP00000430549 ENSP00000428588 ENSP00000430436
Human Recombinant Protein Products:
CCDC69 Antibody Products:
Assay Products for CCDC69: |
Protein
Domains /
Families
for CCDC69 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: A6NI79 |
Function
for CCDC69 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC69 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC69 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CCDC69 (NM_015621) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC69 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC69 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC69 |
|
Pathways & Interactions
for CCDC69 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC69
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for CCDC69 (A6NI792, 3 ENSP000003475864) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for CCDC69 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCDC69
Search CenterWatch for drugs/clinical trials and news about CCDC69 / CCD69
|
Transcripts
for CCDC69 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCDC69 gene: NM_015621.2 Unigene Cluster for CCDC69: Coiled-coil domain containing 69 Hs.655336 [show with all ESTs]Unigene Representative Sequence: AL7137428 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000521308(uc010jhu.3) ENST00000355417(uc011dcq.2 uc003ltq.3)
ENST00000519448 ENST00000518189 ENST00000522964 ENST00000524344 ENST00000522179
ENST00000519740
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC69 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC69 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CCDC69 (NM_015621) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC69 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC69 |
Additional cDNA sequence: AK023767.1 AK225826.1 AK292841.1 AK298063.1 AL080169.1 AL713742.1 AY538626.1 BC013053.1 BC016647.1 12 DOTS entries: DT.453731 DT.100782322 DT.92429372 DT.120847922 DT.306546 DT.91881493 DT.92028136 DT.91770177 DT.92429370 DT.95131091 DT.121230324 DT.305299 24/107 AceView cDNA sequences (see all 107): BI226966 AW401675 AY538626 BG177199 F34826 AA100957 AA808337 CA425459 BM472455 T40652 BI225268 AI287485 BQ955316 BM466120 CD517324 CR613734 AA344102 AW405271 BF338246 AW575165 AI301273 BG832083 BF917183 BE561998
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CCDC69 (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | ^ | 11 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | - | | | | |
| SP3: | | | | | - | | - | | - | | - | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CCDC69
|
Expression
for CCDC69 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCDC69 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CGGCACCTTA
About this image
See CCDC69 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCDC69
SOURCE GeneReport for Unigene cluster: Hs.655336
SABiosciences Custom PCR Arrays for CCDC69
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC69
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CCDC69 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC69 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC69 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC69 |
Orthologs
for CCDC69 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CCDC69 gene from 5/13 species (see all 13) About this table
ENSEMBL Gene Tree for CCDC69 (if available)
TreeFam Gene Tree for CCDC69 (if available) |
Paralogs
for CCDC69 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CCDC69 gene
- MTUS12 MTUS22
1 SIMAP similar gene for CCDC69 using alignment to 6 protein entries: CCD69_HUMAN (see all proteins):MTUS2
CCDC69 for paralogs About GeneDecksing
|
Genomic Variants
for CCDC69 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCDC69 (150560613 - 150603706 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CCDC69: -- | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for CCDC69 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for CCDC69 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCDC69 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CCDC69) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- Role of a novel coiled-coil domain-containing protein CCDC69 in regulating central spindle assembly. (PubMed id 20962590)1 Pal D....Wei Q. (2010)
- The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (2004)
- Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)
|
External Searches for CCDC69 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCDC69 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC69 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCDC69 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCDC69 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CCDC69 gene:
Search GeneIP for patents involving CCDC69
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC69 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for CCDC69 | | OriGene shRNA RFP for CCDC69 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCDC69 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC69 | | | OriGene Protein Over-expression Lysate for CCDC69 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCDC69 | | OriGene 3'-UTR Clone for CCDC69 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC69 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC69 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CCDC69 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCDC69 | | OriGene Custom Protein Services for CCDC69 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC69 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC69 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC69 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCDC69 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC69 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC69 |
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 |  |  |  | |
| | | | Search Tocris compounds for CCDC69 |
| |  |  |  |  | | | | |
 |
 |
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 | | | CCDC69 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC69 |
|  |  |  | | | | ThermoFisher Antibody for CCDC69 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC69 |
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