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Aliases for CCDC68 Gene

Aliases for CCDC68 Gene

  • Coiled-Coil Domain Containing 68 2 3
  • Cutaneous T-Cell Lymphoma-Associated Antigen Se57-1 3 4
  • Cutaneous T-Cell Lymphoma Associated Antigen 2 3
  • CTCL-Associated Antigen Se57-1 3 4
  • Coiled-Coil Domain-Containing Protein 68 3
  • CTCL Tumor Antigen Se57-1 3
  • SE57-1 3

External Ids for CCDC68 Gene

Previous GeneCards Identifiers for CCDC68 Gene

  • GC18M050720
  • GC18M052568
  • GC18M049277

Summaries for CCDC68 Gene

GeneCards Summary for CCDC68 Gene

CCDC68 (Coiled-Coil Domain Containing 68) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC68 Gene

Genomics for CCDC68 Gene

Regulatory Elements for CCDC68 Gene

Genomic Location for CCDC68 Gene

54,901,509 bp from pter
54,959,508 bp from pter
58,000 bases
Minus strand

Genomic View for CCDC68 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC68 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC68 Gene

Proteins for CCDC68 Gene

  • Protein details for CCDC68 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 68
    Protein Accession:
    Secondary Accessions:
    • B2R9I3

    Protein attributes for CCDC68 Gene

    335 amino acids
    Molecular mass:
    38869 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CCDC68 Gene

Proteomics data for CCDC68 Gene at MOPED

Post-translational modifications for CCDC68 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC68 Gene

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for CCDC68

No data available for DME Specific Peptides for CCDC68 Gene

Domains for CCDC68 Gene

Protein Domains for CCDC68 Gene


Suggested Antigen Peptide Sequences for CCDC68 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC68: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC68 Gene

Function for CCDC68 Gene

Gene Ontology (GO) - Molecular Function for CCDC68 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CCDC68: view

Phenotypes for CCDC68 Gene

GenomeRNAi human phenotypes for CCDC68:
genes like me logo Genes that share phenotypes with CCDC68: view

Animal Model Products

miRNA for CCDC68 Gene

miRTarBase miRNAs that target CCDC68

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for CCDC68 Gene

Localization for CCDC68 Gene

Subcellular locations from

Jensen Localization Image for CCDC68 Gene COMPARTMENTS Subcellular localization image for CCDC68 gene
Compartment Confidence
nucleus 3
cytosol 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC68 Gene

Pathways for CCDC68 Gene

SuperPathways for CCDC68 Gene

No Data Available

Interacting Proteins for CCDC68 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000337209 Q9H2F9-CCD68_HUMAN for CCDC68 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for CCDC68 Gene


No data available for Pathways by source for CCDC68 Gene

Transcripts for CCDC68 Gene

Unigene Clusters for CCDC68 Gene

Coiled-coil domain containing 68:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC68 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
SP1: - -

Relevant External Links for CCDC68 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC68 Gene

mRNA expression in normal human tissues for CCDC68 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC68 Gene

This gene is overexpressed in Colon - Transverse (4.3).

Protein differential expression in normal tissues for CCDC68 Gene

This gene is overexpressed in Adipocyte (45.0) and Platelet (16.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CCDC68 Gene

SOURCE GeneReport for Unigene cluster for CCDC68 Gene Hs.120790

mRNA Expression by UniProt/SwissProt for CCDC68 Gene

Tissue specificity: Expressed in bone marrow, colon, small intestine, spleen, testis, trachea and cutaneous T-cell lymphoma (CTCL).
genes like me logo Genes that share expressions with CCDC68: view

Expression partners for CCDC68 Gene

* - Elite partner

Primer Products

In Situ Assay Products

Orthologs for CCDC68 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC68 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC68 35
  • 86.17 (n)
  • 81.49 (a)
CCDC68 36
  • 81 (a)
(Canis familiaris)
Mammalia CCDC68 35
  • 87.36 (n)
  • 82.99 (a)
CCDC68 36
  • 83 (a)
(Mus musculus)
Mammalia Ccdc68 35
  • 78.58 (n)
  • 72.67 (a)
Ccdc68 16
Ccdc68 36
  • 72 (a)
(Pan troglodytes)
Mammalia CCDC68 35
  • 99.8 (n)
  • 99.4 (a)
CCDC68 36
  • 99 (a)
(Monodelphis domestica)
Mammalia CCDC68 36
  • 61 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 67 (a)
-- 36
  • 69 (a)
-- 36
  • 51 (a)
(Anolis carolinensis)
Reptilia CCDC68 36
  • 43 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc68 35
  • 57.17 (n)
  • 48.48 (a)
Species with no ortholog for CCDC68:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC68 Gene

Gene Tree for CCDC68 (if available)
Gene Tree for CCDC68 (if available)

Paralogs for CCDC68 Gene

(1) SIMAP similar genes for CCDC68 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with CCDC68: view

No data available for Paralogs for CCDC68 Gene

Variants for CCDC68 Gene

Sequence variations from dbSNP and Humsavar for CCDC68 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs62091549 -- 54,932,373(+) TTTAG(G/T)AGAGA intron-variant
rs62091531 -- 54,925,620(+) CCCTA(A/C)ATAGA intron-variant
rs62091530 -- 54,923,458(+) AAAAT(A/T)GAAAT intron-variant
rs62091529 -- 54,922,806(+) AACAT(A/G)GTGAG intron-variant
rs62091527 -- 54,920,264(+) TGTTG(G/T)TTTGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC68 Gene

Variant ID Type Subtype PubMed ID
esv268797 CNV Insertion 20981092

Relevant External Links for CCDC68 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC68 Gene

Disorders for CCDC68 Gene

Relevant External Links for CCDC68

Genetic Association Database (GAD)

No disorders were found for CCDC68 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for CCDC68 Gene

Publications for CCDC68 Gene

  1. Tissue expression and sero-reactivity of tumor-specific antigens in colorectal cancer. (PMID: 15142679) Gerhardt A. … Eichmueller S. (Cancer Lett. 2004) 2 3 4
  2. Serological detection of cutaneous T-cell lymphoma-associated antigens. (PMID: 11149944) Eichmueller S. … Schadendorf D. (Proc. Natl. Acad. Sci. U.S.A. 2001) 2 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Genome-wide meta-analysis for severe diabetic retinopathy. (PMID: 21441570) Grassi M.A. … Nicolae D.L. (Hum. Mol. Genet. 2011) 3

Products for CCDC68 Gene

Sources for CCDC68 Gene

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