Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CCDC65 Gene

protein-coding   GIFtS: 44
GCID: GC12P049297

Coiled-Coil Domain Containing 65

  See CCDC65-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Coiled-Coil Domain Containing 651 2
Testis Development Protein NYD-SP282 3
CILD272 5
FAP2502
NYD-SP282
Coiled-Coil Domain-Containing Protein 652

External Ids:    HGNC: 299371   Entrez Gene: 854782   Ensembl: ENSG000001395377   OMIM: 6110885   UniProtKB: Q8IXS23   

Export aliases for CCDC65 gene to outside databases

Previous GC identifers: GC12P047585 GC12P046329


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for CCDC65 Gene:
This gene encodes a sperm tail protein that is highly expressed in adult testis, spermatocytes and spermatids. The
protein plays a critical role in the assembly of the nexin-dynein regulatory complex. Mutations in this gene
result in primary ciliary dyskinesia. (provided by RefSeq, Nov 2013)

GeneCards Summary for CCDC65 Gene:
CCDC65 (coiled-coil domain containing 65) is a protein-coding gene. Diseases associated with CCDC65 include ciliary dyskinesia, primary, 27, and clear cell sarcoma.

UniProtKB/Swiss-Prot: CCD65_HUMAN, Q8IXS2
Function: May play a role in motile cilia function, possibly by acting on the assembly of the nexin-dynein
regulatory complex




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CCDC65 gene promoter:
         c-Fos   PPAR-gamma1   AP-1   HSF2   ATF-2   HSF1 (long)   c-Jun   MIF-1   AP-4   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCCDC65 promoter sequence
   Search Chromatin IP Primers for CCDC65

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC65


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.12   Ensembl cytogenetic band:  12q13.12   HGNC cytogenetic band: 12q13.12

CCDC65 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CCDC65 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P049297:  view genomic region     (about GC identifiers)

Start:
49,297,893 bp from pter      End:
49,325,623 bp from pter
Size:
27,731 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CCD65_HUMAN, Q8IXS2 (See protein sequence)
Recommended Name: Coiled-coil domain-containing protein 65  
Size: 484 amino acids; 57297 Da
Sequence caution: Sequence=BAC05324.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A6NJG5 B2RBE2 Q8N7G4 Q8NA91 Q96JA0
Alternative splicing: 2 isoforms:  Q8IXS2-1   Q8IXS2-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CCDC65: NX_Q8IXS2

Explore proteomics data for CCDC65 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CCDC65 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001273886.1  NP_149115.2  

    ENSEMBL proteins: 
     ENSP00000266984   ENSP00000446569   ENSP00000447157   ENSP00000312706  

    CCDC65 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for CCDC65
    OriGene Protein Over-expression Lysate for CCDC65
    OriGene Custom MassSpec
    OriGene Custom Protein Services for CCDC65
    GenScript Custom Purified and Recombinant Proteins Services for CCDC65
    Novus Biologicals CCDC65 Protein
    Novus Biologicals CCDC65 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CCDC65

     
    Search eBioscience for Proteins for CCDC65 

    CCDC65 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CCDC65
    Novus Biologicals CCDC65 Antibody
    Abcam antibodies for CCDC65
    Cloud-Clone Corp. Antibodies for CCDC65
    Search ThermoFisher Antibodies for CCDC65
    Search LSBio for Antibodies for CCDC65

    CCDC65 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CCDC65
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CCDC65
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CCDC65
    Cloud-Clone Corp. CLIAs for CCDC65
    Search eBioscience for ELISAs for CCDC65 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus

    ProtoNet protein and cluster: Q8IXS2


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CCD65_HUMAN, Q8IXS2
    Function: May play a role in motile cilia function, possibly by acting on the assembly of the nexin-dynein
    regulatory complex

    Phenotypes:
         1 GenomeRNAi human phenotype for CCDC65:

     Increased S DNA content, incre 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCDC65
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCDC65

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CCDC65
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CCDC65

    miRNA
    Products:
        
    miRTarBase miRNAs that target CCDC65:
    hsa-mir-7-5p (MIRT025751)

    Block miRNA regulation of human, mouse, rat CCDC65 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate CCDC65:
    hsa-miR-633 hsa-miR-3613-3p hsa-miR-513a-5p hsa-miR-616* hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmidCCDC65 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CCDC65
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC65

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CCDC65

    Clone
    Products:
         
    OriGene clones in human, mouse for CCDC65 (see all 6)
    OriGene ORF clones in mouse, rat for CCDC65
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CCDC65 (NM_033124)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC65
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC65

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CCDC65
    Browse ESI BIO Cell Lines and PureStem Progenitors for CCDC65 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC65


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CCDC65
    Interactions:

        Search GeneGlobe Interaction Network for CCDC65

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for CCDC65 (ENSP000003127064) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC39ENSP000004057084STRING: ENSP00000405708
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CCDC65 (CCD65)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for CCDC65 gene (2 alternative transcripts): 
    NM_001286957.1  NM_033124.4  

    Unigene Cluster for CCDC65:

    Coiled-coil domain containing 65
    Hs.512805  [show with all ESTs]
    Unigene Representative Sequence: NM_033124
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000266984 ENST00000552942 ENST00000547861 ENST00000320516(uc001rso.3)
    ENST00000552188
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CCDC65 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate CCDC65:
    hsa-miR-633 hsa-miR-3613-3p hsa-miR-513a-5p hsa-miR-616* hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmidCCDC65 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CCDC65
    Predesigned siRNA for gene silencing in human, mouse, rat CCDC65
    Clone
    Products:
         
    OriGene clones in human, mouse for CCDC65 (see all 6)
    OriGene ORF clones in mouse, rat for CCDC65
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CCDC65 (NM_033124)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CCDC65
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC65
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CCDC65
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC65
      QuantiTect SYBR Green Assays in human, mouse, rat CCDC65
      QuantiFast Probe-based Assays in human, mouse, rat CCDC65

    Additional mRNA sequence: 

    AF382188.1 AK093051.1 AK098529.1 AK302082.1 AK314623.1 BC039317.1 

    7 DOTS entries:

    DT.100774160  DT.97812076  DT.121151626  DT.95298694  DT.91993736  DT.91983112  DT.100774159 

    6 AceView cDNA sequences:

    BC039317 AK098529 AX747886 AF382188 NM_033124 AK093051 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    CCDC65 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGTTTAAAA
    CCDC65 Expression
    About this image


    CCDC65 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Brain (Nervous System)
             Choroid Plexus
     
     Testis (Reproductive System)
    CCDC65 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CCDC65 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.512805

    UniProtKB/Swiss-Prot: CCD65_HUMAN, Q8IXS2
    Tissue specificity: Highly expressed in adult testis, in spermatocytes and spermatids. Also observed in
    spermatogonia. Not detected in Leydig cells, nor in fetal testis (at protein level)

        Custom PCR Arrays for CCDC65
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for CCDC65
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC65
    QuantiTect SYBR Green Assays in human, mouse, rat CCDC65
    QuantiFast Probe-based Assays in human, mouse, rat CCDC65
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC65

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for CCDC65 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ccdc651 , 5 coiled-coil domain containing 651, 5 81.65(n)1
    83.01(a)1
      15 (54.65 cM)5
    1058331  NM_153518.11  NP_705738.11 
     987082275 
    chicken
    (Gallus gallus)
    Aves CCDC656
    coiled-coil domain containing 65
    43(a)
    1 ↔ 1
    AADN03021979.1(816-1746)
    lizard
    (Anolis carolinensis)
    Reptilia CCDC656
    coiled-coil domain containing 65
    61(a)
    1 ↔ 1
    2(94181178-94192131)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia ccdc651 coiled-coil domain containing 65 62.54(n)
    62.26(a)
      100491104  XM_002935105.2  XP_002935151.2 
    zebrafish
    (Danio rerio)
    Actinopterygii ccdc651 coiled-coil domain containing 65 53.23(n)
    43.39(a)
      368824  NM_001002603.2  NP_001002603.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG302591 CG30259 43.15(n)
    28.35(a)
      37606  NM_137864.2  NP_611708.2 


    ENSEMBL Gene Tree for CCDC65 (if available)
    TreeFam Gene Tree for CCDC65 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for CCDC65 gene

    Find genes that share paralogs with CCDC65           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for CCDC65
    PGOHUM00000245543


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for CCDC65 (see all 453)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1122947891,2
    C--46334217(+) CCAGGATTAT   
      TATT
    /-
    ATTAT
    1 -- int11Minor allele frequency- -:0.50CSA 2
    rs74890361,2
    C,F,A--49295949(+) aaaaaG/Agagag 1 -- us2k1 trp32Minor allele frequency- A:0.40NA EA 240
    rs1812487081,2
    --49295982(+) AGAGAC/GAAAGA 1 -- us2k10--------
    rs1861305531,2
    --49296026(+) TAATCG/TACTTT 1 -- us2k10--------
    rs44336141,2
    C,F,H--49296056(-) tatccG/Agaaaa 1 -- us2k110Minor allele frequency- A:0.31EA NS NA CSA WA 660
    rs1493219161,2
    --49296128(+) TAGGGG/TTTTTT 1 -- us2k10--------
    rs1917221681,2
    --49296143(+) CCGAAC/TATGGT 1 -- us2k10--------
    rs1821813541,2
    --49296178(+) TTTGGA/GAGGCC 1 -- us2k10--------
    rs1445671351,2
    C--49296398(+) TGACAA/GAGTGA 1 -- us2k10--------
    rs1876107241,2
    C--49296522(+) TTGACC/TTCTGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CCDC65 (49297893 - 49325623 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CCDC65:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv832404CNV Gain17160897

    Human Gene Mutation Database (HGMD): CCDC65
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CCDC65
    DNA2.0 Custom Variant and Variant Library Synthesis for CCDC65

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 611088   
    OMIM disorders: 615504  
    UniProtKB/Swiss-Prot: CCD65_HUMAN, Q8IXS2
  • Ciliary dyskinesia, primary, 27 (CILD27) [MIM:615504]: A disorder characterized by abnormalities of
    motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to
    defects in the respiratory cilia. Patients may exhibit randomization of left-right body asymmetry and situs
    inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs
    inversus is referred to as Kartagener syndrome. Note=The disease is caused by mutations affecting the gene
    represented in this entry. Cilia ultrastructure show normal outer dynein arms, radial spokes and central pairs,
    but a reduction in inner dynein arms and nexin links. In 5%-15% of cilia, microtubules are disorganized. Nasal
    epithelial cilia reveal a stiff, dyskinetic cilia waveform

  • 3 diseases for CCDC65:    
    About MalaCards
    ciliary dyskinesia, primary, 27    clear cell sarcoma    ciliary dyskinesia, primary, 19

    1 disease from the University of Copenhagen DISEASES database for CCDC65:
    Clear cell sarcoma

    Find genes that share disorders with CCDC65           About GenesLikeMe


    Export disorders for CCDC65 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for CCDC65 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with CCDC65)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of a novel sperm tail protein, NYD- SP28. (PubMed id 17089017)1, 2, 3 Zheng Y.... Sha J.-H. (Int. J. Mol. Med. 2006)
    2. Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia. (PubMed id 24094744)1, 2 Austin-Tse C....Hildebrandt F. (Am. J. Hum. Genet. 2013)
    3. Building blocks of the nexin-dynein regulatory complex in Chlamydomonas flagella. (PubMed id 21700706)1, 3 Lin J....Nicastro D. (J. Biol. Chem. 2011)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. CCDC65 mutation causes primary ciliary dyskinesia with normal ultrastructure and hyperkinetic cilia. (PubMed id 23991085)1 Horani A....Kerem E. (PLoS ONE 2013)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    7. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (Nature 2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (Genome Res. 1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 85478 HGNC: 29937 AceView: NYD-SP28 Ensembl:ENSG00000139537 euGenes: HUgn85478
    ECgene: CCDC65 H-InvDB: CCDC65

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for CCDC65 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for CCDC65 gene:
    Search GeneIP for patents involving CCDC65

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CCDC65  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for CCDC65  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for CCDC65  
     OriGene qSTAR qPCR primer pairs in human, mouse for CCDC65   OriGene Purified Protein for CCDC65  
     OriGene ORF clones in mouse, rat for CCDC65   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CCDC65   OriGene Custom Protein Services for CCDC65  

     
     
     Block miRNA regulation of human, mouse, rat CCDC65 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CCDC65
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CCDC65 Predesigned siRNA for gene silencing in human, mouse, rat CCDC65
     QuantiFast Probe-based Assays in human, mouse, rat CCDC65 QuantiTect SYBR Green Assays in human, mouse, rat CCDC65
     Custom PCR Arrays for CCDC65 Search Chromatin IP Primers for CCDC65
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CCDC65  Search GeneGlobe Interaction Network for CCDC65
     Regulatory tfbs in CCDC65 promoter
     GenScript Custom Purified and Recombinant Proteins Services for CCDC65 GenScript cDNA clones with any tag delivered in your preferred vector for CCDC65
     GenScript Custom Assay Services for CCDC65 GenScript Custom overexpressing Cell Line Services for CCDC65
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for CCDC65 (CCD65)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     CCDC65 antibodies
     CCDC65 proteins
     CCDC65 lysates
     Antibodies for CCDC65
     See all of Abcam's Antibodies, Kits and Proteins for CCDC65
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for CCDC65
     Antibodies for CCDC65
     ELISAs for CCDC65
     CLIAs for CCDC65



     Browse ESI BIO Cell Lines and PureStem Progenitors for CCDC65
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC65
     SwitchGear 3'UTR luciferase reporter plasmids for CCDC65
     SwitchGear Promoter luciferase reporter plasmids for CCDC65
     Search ThermoFisher Antibodies for CCDC65
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC65
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CCDC65
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CCDC65
     Search LSBio for Antibodies for CCDC65
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for CCDC65
      Search eBioscience for proteins for CCDC65
      Search eBioscience for elisas for CCDC65
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CCDC65 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4