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Aliases for CCDC64B Gene

Aliases for CCDC64B Gene

  • Coiled-Coil Domain Containing 64B 2 3 5
  • Coiled-Coil Domain-Containing Protein 64B 3 4
  • BICD-Related Protein 2 3 4
  • BICDR-2 3 4
  • BICDR2 4

External Ids for CCDC64B Gene

Previous GeneCards Identifiers for CCDC64B Gene

  • GC16M003018
  • GC16M003080

Summaries for CCDC64B Gene

GeneCards Summary for CCDC64B Gene

CCDC64B (Coiled-Coil Domain Containing 64B) is a Protein Coding gene. GO annotations related to this gene include signal transducer activity and Rab GTPase binding. An important paralog of this gene is CCDC64.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC64B Gene

Genomics for CCDC64B Gene

Regulatory Elements for CCDC64B Gene

Enhancers for CCDC64B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CCDC64B on UCSC Golden Path with GeneCards custom track

Genomic Location for CCDC64B Gene

3,027,682 bp from pter
3,036,963 bp from pter
9,282 bases
Minus strand

Genomic View for CCDC64B Gene

Genes around CCDC64B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC64B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC64B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC64B Gene

Proteins for CCDC64B Gene

  • Protein details for CCDC64B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Bicaudal D-related protein 2
    Protein Accession:
    Secondary Accessions:
    • Q658L9

    Protein attributes for CCDC64B Gene

    508 amino acids
    Molecular mass:
    56834 Da
    Quaternary structure:
    • Interacts with RAB13.

    Alternative splice isoforms for CCDC64B Gene


neXtProt entry for CCDC64B Gene

Proteomics data for CCDC64B Gene at MOPED

Post-translational modifications for CCDC64B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC64B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CCDC64B Gene

Domains & Families for CCDC64B Gene

Protein Domains for CCDC64B Gene


Suggested Antigen Peptide Sequences for CCDC64B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the BICDR family.
  • Belongs to the BICDR family.
genes like me logo Genes that share domains with CCDC64B: view

No data available for Gene Families for CCDC64B Gene

Function for CCDC64B Gene

Gene Ontology (GO) - Molecular Function for CCDC64B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0017137 Rab GTPase binding IEA --
genes like me logo Genes that share ontologies with CCDC64B: view

Phenotypes for CCDC64B Gene

GenomeRNAi human phenotypes for CCDC64B:
genes like me logo Genes that share phenotypes with CCDC64B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC64B Gene

Localization for CCDC64B Gene

Subcellular locations from

Jensen Localization Image for CCDC64B Gene COMPARTMENTS Subcellular localization image for CCDC64B gene
Compartment Confidence
cytosol 3
nucleus 3
cytoskeleton 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC64B Gene

Pathways & Interactions for CCDC64B Gene

SuperPathways for CCDC64B Gene

No Data Available

Gene Ontology (GO) - Biological Process for CCDC64B Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC64B Gene

Drugs & Compounds for CCDC64B Gene

No Compound Related Data Available

Transcripts for CCDC64B Gene

Unigene Clusters for CCDC64B Gene

Coiled-coil domain containing 64B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC64B Gene

No ASD Table

Relevant External Links for CCDC64B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC64B Gene

mRNA expression in normal human tissues for CCDC64B Gene

mRNA differential expression in normal tissues according to GTEx for CCDC64B Gene

This gene is overexpressed in Pancreas (x11.4), Esophagus - Mucosa (x8.9), and Minor Salivary Gland (x4.4).

Protein differential expression in normal tissues from HIPED for CCDC64B Gene

This gene is overexpressed in Cervix (48.1) and Urine (14.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CCDC64B Gene

SOURCE GeneReport for Unigene cluster for CCDC64B Gene Hs.513285

genes like me logo Genes that share expression patterns with CCDC64B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CCDC64B Gene

Orthologs for CCDC64B Gene

This gene was present in the common ancestor of animals.

Orthologs for CCDC64B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC64B 35
  • 85.08 (n)
  • 85.94 (a)
CCDC64B 36
  • 85 (a)
(Canis familiaris)
Mammalia CCDC64B 35
  • 86.34 (n)
  • 87.72 (a)
CCDC64B 36
  • 87 (a)
(Mus musculus)
Mammalia Ccdc64b 35
  • 80.96 (n)
  • 84.58 (a)
Ccdc64b 16
Ccdc64b 36
  • 84 (a)
(Pan troglodytes)
Mammalia CCDC64B 35
  • 99.34 (n)
  • 98.82 (a)
CCDC64B 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ccdc64b 35
  • 82.21 (n)
  • 86.56 (a)
(Monodelphis domestica)
Mammalia CCDC64B 36
  • 72 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC64B 36
  • 56 (a)
(Anolis carolinensis)
Reptilia CCDC64B 36
  • 42 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc64b 35
  • 50.47 (n)
  • 38.71 (a)
(Danio rerio)
Actinopterygii CCDC64B 36
  • 15 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG32137 36
  • 22 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 30 (a)
CSA.2341 36
  • 18 (a)
Species with no ortholog for CCDC64B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC64B Gene

Gene Tree for CCDC64B (if available)
Gene Tree for CCDC64B (if available)

Paralogs for CCDC64B Gene

Paralogs for CCDC64B Gene

(1) SIMAP similar genes for CCDC64B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CCDC64B: view

Variants for CCDC64B Gene

Sequence variations from dbSNP and Humsavar for CCDC64B Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs2244494 - 3,029,684(-) GCTGC(A/G)GCGGC reference, missense
VAR_060543 -
rs5815143 -- 3,028,616(+) GGATC(-/ATT)ATAAC intron-variant
rs2011561 -- 3,029,011(-) CCCCA(C/G)CCCGC intron-variant
rs2079244 -- 3,028,543(-) CGGGT(A/C)CAGAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC64B Gene

Variant ID Type Subtype PubMed ID
nsv905162 CNV Gain 21882294
nsv905170 CNV Loss 21882294
dgv2575n71 CNV Loss 21882294
dgv2576n71 CNV Loss 21882294
nsv509588 CNV Insertion 20534489
nsv510673 CNV Loss 20534489
nsv905185 CNV Loss 21882294
dgv2577n71 CNV Loss 21882294
dgv2578n71 CNV Loss 21882294
dgv2579n71 CNV Loss 21882294
nsv833125 CNV Loss 17160897

Variation tolerance for CCDC64B Gene

Gene Damage Index Score: 15.77; 97.35% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for CCDC64B Gene

Disorders for CCDC64B Gene

Relevant External Links for CCDC64B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC64B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC64B Gene

Publications for CCDC64B Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 67
  2. Large-scale analysis of the human ubiquitin-related proteome. (PMID: 16196087) Matsumoto M. … Nakayama K.I. (Proteomics 2005) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CCDC64B Gene

Sources for CCDC64B Gene