CCDC64B Gene
protein-coding GIFtS: 38
GCID: GC16M003080
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|
coiled-coil domain containing 64B
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Aliases
for CCDC64B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Coiled-Coil Domain Containing 64B1 2 | | Coiled-Coil Domain-Containing Protein 64B2 3 | | BICDR-22 3 | | BICD-Related Protein 22 3 | | Bicaudal D-Related Protein 22 | | BICDR23 |
Export aliases for CCDC64B gene to outside databasesPrevious GC identifer: GC16M003018 |
Summaries
for CCDC64B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCDC64B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCDC64B gene promoter:
STAT3 HNF-4alpha2 HNF-4alpha1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC64B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC64B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3CCDC64B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M003080: view genomic region
(about GC identifiers)
Start:
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3,077,683 bp from pter |
End:
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3,086,927 bp from pter |
Size:
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9,245 bases |
Orientation:
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minus strand |
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Proteins
for CCDC64B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: BICR2_HUMAN, A1A5D9 (See
protein sequence)Recommended Name: Bicaudal D-related protein 2 Size: 508 amino acids; 56834 Da
Subunit: Interacts with RAB13 (By similarity)
Secondary accessions: Q658L9Alternative splicing: 2 isoforms: A1A5D9-1 A1A5D9-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CCDC64B: NX_A1A5D9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A1A5D9
CCDC64B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001096645.1
ENSEMBL proteins: ENSP00000461724 ENSP00000459043 ENSP00000373998
Human Recombinant Protein Products:
CCDC64B Antibody Products:
Assay Products for CCDC64B: |
Protein
Domains /
Families
for CCDC64B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: A1A5D9 UniProtKB/Swiss-Prot: BICR2_HUMAN, A1A5D9Similarity: Belongs to the BICDR family |
Function
for CCDC64B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC64B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC64B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CCDC64B (NM_001103175) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC64B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC64B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC64B |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0017137 | Rab GTPase binding |
IEA | -- |
CCDC64B for ontologies About GeneDecksing
|
Pathways & Interactions
for CCDC64B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC64B
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
5/10 Interacting proteins for CCDC64B (A1A5D93 ENSP000003739984) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
|
Drugs & Compounds
for CCDC64B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCDC64B
Search CenterWatch for drugs/clinical trials and news about CCDC64B / BICR2
|
Transcripts
for CCDC64B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCDC64B gene: NM_001103175.1 Unigene Cluster for CCDC64B: Coiled-coil domain containing 64B Hs.513285 [show with all ESTs]Unigene Representative Sequence: NM_0011031755 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000572240 ENST00000573514(uc002cte.4) ENST00000572449 ENST00000576826(uc010bta.1)
ENST00000389347(uc002ctf.4)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC64B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC64B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CCDC64B (NM_001103175) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC64B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC64B |
Additional cDNA sequence: AK307181.1 BC015446.2 BC128602.1 6 DOTS entries: DT.408652 DT.408651 DT.92434372 DT.120679676 DT.91954078 DT.97821943 24/37 AceView cDNA sequences (see all 37): AI734167 BM920276 AA454758 AW044349 AI734191 AI732781 AW044375 AA459895 AW087259 BM977046 BM310479 BG142147 AL833717 AI271468 BG747439 AI732810 BG680744 AW089793 AI689487 BX118386 AL833749 AI631651 BE552074 BM981506
GeneLoc Exon Structure
|
Expression
for CCDC64B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCDC64B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTAAAAAAGC
About this image
See CCDC64B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCDC64B
SOURCE GeneReport for Unigene cluster: Hs.513285
SABiosciences Custom PCR Arrays for CCDC64B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC64B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CCDC64B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC64B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC64B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC64B |
Orthologs
for CCDC64B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CCDC64B gene from 3/16 species (see all 16) About this table
ENSEMBL Gene Tree for CCDC64B (if available)
TreeFam Gene Tree for CCDC64B (if available) |
Paralogs
for CCDC64B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CCDC64B gene
- CCDC642
1 SIMAP similar gene for CCDC64B using alignment to 1 protein entry: BICR2_HUMAN:CCDC64
CCDC64B for paralogs About GeneDecksing
|
Genomic Variants
for CCDC64B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCDC64B (3077683 - 3086927 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CCDC64B: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC64B |
|
Disorders
/ Diseases
for CCDC64B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for CCDC64B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCDC64B gene integrated from 9 sources:
(articles sorted by number of sources associating them with CCDC64B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Large-scale analysis of the human ubiquitin-related p roteome. (PubMed id 16196087)1 Matsumoto M....Nakayama K.I. (2005)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for CCDC64B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCDC64B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC64B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCDC64B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCDC64B | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for CCDC64B gene:
Search GeneIP for patents involving CCDC64B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC64B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CCDC64B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCDC64B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC64B | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCDC64B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC64B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC64B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCDC64B | | OriGene Custom Protein Services for CCDC64B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC64B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC64B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC64B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCDC64B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC64B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC64B |
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 |  |  |  | |
| | | | Search Tocris compounds for CCDC64B |
| |  |  |  |  | | | | |
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 | | | CCDC64B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC64B |
|  |  |  | | | | Search ThermoFisher Antibodies for CCDC64B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CCDC64B |
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