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Aliases for CCDC63 Gene

Aliases for CCDC63 Gene

  • Coiled-Coil Domain Containing 63 2 3
  • Outer Row Dynein Assembly 5 Homolog (Chlamydomonas) 2
  • Coiled-Coil Domain-Containing Protein 63 3
  • Outer Row Dynein Assembly 5 Homolog 3
  • ODA5 3

External Ids for CCDC63 Gene

Previous GeneCards Identifiers for CCDC63 Gene

  • GC12P109748
  • GC12P111284
  • GC12P108301

Summaries for CCDC63 Gene

GeneCards Summary for CCDC63 Gene

CCDC63 (Coiled-Coil Domain Containing 63) is a Protein Coding gene. An important paralog of this gene is CCDC114.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC63 Gene

Genomics for CCDC63 Gene

Regulatory Elements for CCDC63 Gene

Genomic Location for CCDC63 Gene

Start:
110,846,769 bp from pter
End:
110,907,535 bp from pter
Size:
60,767 bases
Orientation:
Plus strand

Genomic View for CCDC63 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CCDC63 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC63 Gene

Proteins for CCDC63 Gene

  • Protein details for CCDC63 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NA47-CCD63_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 63
    Protein Accession:
    Q8NA47
    Secondary Accessions:
    • B4DY03
    • Q0P603
    • Q6P2E1

    Protein attributes for CCDC63 Gene

    Size:
    563 amino acids
    Molecular mass:
    66250 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH44815.1; Type=Frameshift; Positions=241; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC63 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CCDC63 Gene

Proteomics data for CCDC63 Gene at MOPED

Post-translational modifications for CCDC63 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CCDC63 Gene

No data available for DME Specific Peptides for CCDC63 Gene

Domains for CCDC63 Gene

Protein Domains for CCDC63 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CCDC63 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC63: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC63 Gene

Function for CCDC63 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CCDC63 Gene

Localization for CCDC63 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CCDC63 Gene COMPARTMENTS Subcellular localization image for CCDC63 gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CCDC63 Gene

Pathways for CCDC63 Gene

SuperPathways for CCDC63 Gene

No Data Available

Interacting Proteins for CCDC63 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000312399%0d%0a9606.ENSP00000308312%0d%0a9606.ENSP00000242317%0d%0a9606.ENSP00000262455%0d%0a
Selected Interacting proteins: ENSP00000312399 Q8NA47-CCD63_HUMAN for CCDC63 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for CCDC63 Gene

None

No data available for Pathways by source for CCDC63 Gene

Transcripts for CCDC63 Gene

Unigene Clusters for CCDC63 Gene

Coiled-coil domain containing 63:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC63 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
SP1:
SP2: - -
SP3:
SP4:

Relevant External Links for CCDC63 Gene

GeneLoc Exon Structure for
CCDC63
ECgene alternative splicing isoforms for
CCDC63

Expression for CCDC63 Gene

mRNA expression in normal human tissues for CCDC63 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CCDC63 Gene

This gene is overexpressed in Testis (49.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CCDC63 Gene

SOURCE GeneReport for Unigene cluster for CCDC63 Gene Hs.437141

genes like me logo Genes that share expressions with CCDC63: view

No data available for mRNA Expression by UniProt/SwissProt for CCDC63 Gene

Orthologs for CCDC63 Gene

This gene was present in the common ancestor of animals.

Orthologs for CCDC63 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CCDC63 35
  • 98.93 (n)
  • 99.11 (a)
CCDC63 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CCDC63 35
  • 84.44 (n)
  • 79.82 (a)
CCDC63 36
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC63 35
  • 83.24 (n)
  • 77.96 (a)
CCDC63 36
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc63 35
  • 76.33 (n)
  • 72.45 (a)
Ccdc63 16
Ccdc63 36
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CCDC63 36
  • 59 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC63 36
  • 58 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc63 35
  • 79.08 (n)
  • 76.41 (a)
chicken
(Gallus gallus)
Aves CCDC63 35
  • 59.96 (n)
  • 45.79 (a)
CCDC63 36
  • 43 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC63 36
  • 45 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG14905 36
  • 23 (a)
ManyToMany
CG17083 36
  • 16 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 32 (a)
OneToOne
Species with no ortholog for CCDC63:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CCDC63 Gene

ENSEMBL:
Gene Tree for CCDC63 (if available)
TreeFam:
Gene Tree for CCDC63 (if available)

Paralogs for CCDC63 Gene

Paralogs for CCDC63 Gene

genes like me logo Genes that share paralogs with CCDC63: view

Variants for CCDC63 Gene

Sequence variations from dbSNP and Humsavar for CCDC63 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs756838 -- 110,854,781(+) CAGGA(A/T)GGGGA intron-variant
rs886132 -- 110,853,067(+) TCTGT(C/G)CTCAC intron-variant
rs1011300 -- 110,906,526(+) CTTGC(A/G)TGACT intron-variant
rs1468131 -- 110,878,890(-) AAGTT(G/T)TTTTT intron-variant
rs1858881 -- 110,896,313(-) TAAAG(A/G)TGCAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC63 Gene

Variant ID Type Subtype PubMed ID
nsv509476 CNV Insertion 20534489
nsv7236 OTHER Inversion 18451855
esv1606344 CNV Deletion 17803354
nsv513365 CNV Insertion 21212237
esv2171541 CNV Deletion 18987734
esv1606463 CNV Insertion 17803354

Relevant External Links for CCDC63 Gene

HapMap Linkage Disequilibrium report
CCDC63

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC63 Gene

Disorders for CCDC63 Gene

Relevant External Links for CCDC63

Genetic Association Database (GAD)
CCDC63
Human Genome Epidemiology (HuGE) Navigator
CCDC63
genes like me logo Genes that share disorders with CCDC63: view

No data available for UniProtKB/Swiss-Prot for CCDC63 Gene

Publications for CCDC63 Gene

  1. Genome-wide association studies identify genetic loci related to alcohol consumption in Korean men. (PMID: 21270382) Baik I. … Shin C. (Am. J. Clin. Nutr. 2011) 3 48
  2. Confirmation of ALDH2 as a Major locus of drinking behavior and of its variants regulating multiple metabolic phenotypes in a Japanese population. (PMID: 21372407) Takeuchi F. … Kato N. (Circ. J. 2011) 3 48
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CCDC63 Gene

Sources for CCDC63 Gene

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