CCDC61 Gene
protein-coding GIFtS: 34
GCID: GC19P046498
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coiled-coil domain containing 61
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Aliases
for CCDC61 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Coiled-Coil Domain Containing 611 2 | | Coiled-Coil Domain-Containing Protein 612 |
Export aliases for CCDC61 gene to outside databasesPrevious GC identifers: GC19P051191 GC19P042926 |
Summaries
for CCDC61 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CCDC61 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CCDC61 gene promoter:
E2F-4 E2F-3a STAT1 E2F-5 p53 E2F-2 STAT1alpha GATA-2 E2F E2F-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CCDC61
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC61 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.32 Ensembl cytogenetic band: 19q13.32 HGNC cytogenetic band: 19q13.32CCDC61 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P046498: view genomic region
(about GC identifiers)
Start:
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46,498,339 bp from pter |
End:
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46,521,874 bp from pter |
Size:
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23,536 bases |
Orientation:
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plus strand |
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Proteins
for CCDC61 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CCD61_HUMAN, Q9Y6R9 (See
protein sequence)Recommended Name: Coiled-coil domain-containing protein 61 Size: 474 amino acids; 53207 Da
Sequence caution: Sequence=AAD38244.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=AAF98366.1; Type=Erroneous gene model prediction;
Secondary accessions: Q9HDB6Explore the universe of human proteins at neXtProt for CCDC61: NX_Q9Y6R9
CCDC61 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001254652.1
ENSEMBL proteins: ENSP00000263284 ENSP00000444279
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005813 | centrosome |
IDA | -- |
CCDC61 for ontologies About GeneDecksing
CCDC61 Antibody Products:
Assay Products for CCDC61: |
Protein
Domains /
Families
for CCDC61 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9Y6R9 |
Function
for CCDC61 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC61
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC61
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CCDC61 (NM_001080402) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC61 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CCDC61 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC61 |
|
Pathways & Interactions
for CCDC61 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CCDC61
|
Drugs & Compounds
for CCDC61 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CCDC61
Search CenterWatch for drugs/clinical trials and news about CCDC61 / CCD61
|
Transcripts
for CCDC61 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CCDC61 gene (2 alternative transcripts): NM_001080402.1 NM_001267723.1 Unigene Cluster for CCDC61: Coiled-coil domain containing 61 Hs.515479 [show with all ESTs]Unigene Representative Sequence: NM_0012677232 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000263284(uc002pdw.3 uc021uwd.1) ENST00000536603
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC61
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC61
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CCDC61 (NM_001080402) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CCDC61 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CCDC61 |
Additional cDNA sequence: GQ375050.1 6 DOTS entries: DT.307996 DT.434098 DT.95305974 DT.95354295 DT.100743969 DT.91715679
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for CCDC61 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 |
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| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | - | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CCDC61
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Expression
for CCDC61 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CCDC61 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGGGAGGGA
About this image
See CCDC61 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CCDC61
SOURCE GeneReport for Unigene cluster: Hs.515479
SABiosciences Custom PCR Arrays for CCDC61
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC61
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CCDC61 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC61 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC61 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC61 |
Orthologs
for CCDC61 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CCDC61 gene from 4/13 species (see all 13) About this table
Species with no ortholog for CCDC61
ENSEMBL Gene Tree for CCDC61 (if available)
TreeFam Gene Tree for CCDC61 (if available) |
Paralogs
for CCDC61 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CCDC61 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CCDC61 (46498339 - 46521874 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CCDC61
1 Indel: 67567 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC61 |
|
Disorders
/ Diseases
for CCDC61 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 CCDC61 for disorders About MalaCards
CCDC61 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: CCDC61 (3 documents)
Export disorders for CCDC61 gene to outside databases
|
Publications
for CCDC61 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CCDC61 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CCDC61) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
|
External Searches for CCDC61 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CCDC61 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CCDC61 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CCDC61 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CCDC61 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CCDC61 gene:
Search GeneIP for patents involving CCDC61
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CCDC61 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CCDC61 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CCDC61 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CCDC61 | | | OriGene Protein Over-expression Lysate for CCDC61 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CCDC61 | | OriGene 3'-UTR Clone for CCDC61 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC61 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CCDC61 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CCDC61 | | OriGene Custom Protein Services for CCDC61 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CCDC61 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CCDC61 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CCDC61 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CCDC61 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CCDC61 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CCDC61 |
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 |  |  |  | |
| | | | Search Tocris compounds for CCDC61 |
| |  |  |  |  | | | | |
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 | | | CCDC61 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CCDC61 |
|  |  |  | | | | Search ThermoFisher Antibodies for CCDC61 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CCDC61 |
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