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Aliases for CCDC61 Gene

Aliases for CCDC61 Gene

  • Coiled-Coil Domain Containing 61 2 3 5

External Ids for CCDC61 Gene

Previous GeneCards Identifiers for CCDC61 Gene

  • GC19P051191
  • GC19P046498
  • GC19P042926

Summaries for CCDC61 Gene

GeneCards Summary for CCDC61 Gene

CCDC61 (Coiled-Coil Domain Containing 61) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CCDC61 Gene

Genomics for CCDC61 Gene

Regulatory Elements for CCDC61 Gene

Enhancers for CCDC61 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around CCDC61 on UCSC Golden Path with GeneCards custom track

Promoters for CCDC61 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for CCDC61 Gene

45,995,451 bp from pter
46,021,318 bp from pter
25,868 bases
Plus strand

Genomic View for CCDC61 Gene

Genes around CCDC61 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CCDC61 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CCDC61 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CCDC61 Gene

Proteins for CCDC61 Gene

  • Protein details for CCDC61 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Coiled-coil domain-containing protein 61
    Protein Accession:
    Secondary Accessions:
    • C8CAP4
    • Q9HDB6

    Protein attributes for CCDC61 Gene

    512 amino acids
    Molecular mass:
    57368 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAD38244.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAD38244.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAF98366.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for CCDC61 Gene


neXtProt entry for CCDC61 Gene

Post-translational modifications for CCDC61 Gene

  • Ubiquitination at Lys 364 and Lys 480
  • Modification sites at PhosphoSitePlus

Other Protein References for CCDC61 Gene

No data available for DME Specific Peptides for CCDC61 Gene

Domains & Families for CCDC61 Gene

Protein Domains for CCDC61 Gene


Suggested Antigen Peptide Sequences for CCDC61 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CCDC61: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CCDC61 Gene

Function for CCDC61 Gene

genes like me logo Genes that share phenotypes with CCDC61: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CCDC61 Gene

Localization for CCDC61 Gene

Subcellular locations from

Jensen Localization Image for CCDC61 Gene COMPARTMENTS Subcellular localization image for CCDC61 gene
Compartment Confidence
cytoskeleton 5
nucleus 4
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for CCDC61 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005813 centrosome IDA 21399614
genes like me logo Genes that share ontologies with CCDC61: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CCDC61 Gene

Pathways & Interactions for CCDC61 Gene

SuperPathways for CCDC61 Gene

No Data Available

Interacting Proteins for CCDC61 Gene

Selected Interacting proteins: Q9Y6R9-CCD61_HUMAN for CCDC61 Gene via IID

Gene Ontology (GO) - Biological Process for CCDC61 Gene


No data available for Pathways by source and SIGNOR curated interactions for CCDC61 Gene

Drugs & Compounds for CCDC61 Gene

No Compound Related Data Available

Transcripts for CCDC61 Gene

mRNA/cDNA for CCDC61 Gene

(5) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CCDC61 Gene

Coiled-coil domain containing 61:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CCDC61 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
SP3: -

Relevant External Links for CCDC61 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CCDC61 Gene

mRNA expression in normal human tissues for CCDC61 Gene

Protein differential expression in normal tissues from HIPED for CCDC61 Gene

This gene is overexpressed in Adrenal (53.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CCDC61 Gene

Protein tissue co-expression partners for CCDC61 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CCDC61 Gene:


SOURCE GeneReport for Unigene cluster for CCDC61 Gene:

genes like me logo Genes that share expression patterns with CCDC61: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CCDC61 Gene

Orthologs for CCDC61 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CCDC61 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC61 34
  • 89.22 (n)
  • 89.8 (a)
CCDC61 35
  • 88 (a)
(Canis familiaris)
Mammalia CCDC61 34
  • 87.61 (n)
  • 90.02 (a)
CCDC61 35
  • 89 (a)
(Mus musculus)
Mammalia Ccdc61 34
  • 84.38 (n)
  • 86.02 (a)
Ccdc61 16
Ccdc61 35
  • 85 (a)
(Pan troglodytes)
Mammalia CCDC61 34
  • 99.46 (n)
  • 99.46 (a)
CCDC61 35
  • 99 (a)
(Rattus norvegicus)
Mammalia Ccdc61 34
  • 83.53 (n)
  • 84.78 (a)
(Monodelphis domestica)
Mammalia CCDC61 35
  • 47 (a)
(Gallus gallus)
Aves CCDC61 35
  • 44 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 74 (a)
-- 35
  • 42 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100486261 34
  • 51.69 (n)
  • 48.94 (a)
(Danio rerio)
Actinopterygii ccdc61 34
  • 50.75 (n)
  • 45.9 (a)
ccdc61 35
  • 41 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 65 (a)
Species where no ortholog for CCDC61 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CCDC61 Gene

Gene Tree for CCDC61 (if available)
Gene Tree for CCDC61 (if available)

Paralogs for CCDC61 Gene

No data available for Paralogs for CCDC61 Gene

Variants for CCDC61 Gene

Sequence variations from dbSNP and Humsavar for CCDC61 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs17652384 -- 45,999,459(+) GCCCA(G/T)CTAGG intron-variant, utr-variant-5-prime
rs17652418 -- 45,999,536(+) AGGTG(C/T)GGGCT intron-variant, utr-variant-5-prime
rs4280360 -- 46,004,000(+) gtggc(A/G)ccatc intron-variant
rs11330181 -- 46,008,431(+) GAGAC(-/A)AGAGT intron-variant
rs28479346 -- 46,010,066(+) AACAT(G/T)TATGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CCDC61 Gene

Variant ID Type Subtype PubMed ID
esv25420 CNV loss 19812545

Variation tolerance for CCDC61 Gene

Residual Variation Intolerance Score: 88.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.84; 83.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CCDC61 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CCDC61 Gene

Disorders for CCDC61 Gene

Relevant External Links for CCDC61

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CCDC61 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CCDC61 Gene

Publications for CCDC61 Gene

  1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 46 65
  2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4 65
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4 65
  4. Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. (PMID: 25281560) Lambert J.P. … Gingras A.C. (J Proteomics 2015) 3 65
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 65

Products for CCDC61 Gene

Sources for CCDC61 Gene

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